Mutagenetix > Incidental Mutation

Incidental Mutation 'R2301:Gm16380'

244427

Institutional Source

Beutler Lab

Gene Symbol

Gm16380

Ensembl Gene

ENSMUSG00000059830

Gene Name

predicted pseudogene 16380

Synonyms

MMRRC Submission

040300-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.162) question?

Stock #

R2301 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

53791368-53791845 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

A to G at 53791484 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000077997

SMART Domains

Protein: ENSMUSP00000129245
Gene: ENSMUSG00000059830

Domain	Start	End	E-Value	Type
Pfam:Siva	1	152	6.6e-65	PFAM

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.1%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 27 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Catsper1	A	G	19: 5,390,426 (GRCm39)	K602E	probably benign	Het
Chst13	A	T	6: 90,295,271 (GRCm39)	S47R	probably damaging	Het
Clrn1	T	G	3: 58,753,773 (GRCm39)	Y196S	probably damaging	Het
Csmd3	A	G	15: 47,595,394 (GRCm39)	S2022P	probably damaging	Het
Dnhd1	T	A	7: 105,354,606 (GRCm39)	F3123I	probably damaging	Het
Dpp9	C	T	17: 56,501,973 (GRCm39)	E532K	probably benign	Het
Eif4g3	T	A	4: 137,899,970 (GRCm39)	D970E	probably damaging	Het
Fam222b	T	C	11: 78,045,369 (GRCm39)	V310A	probably damaging	Het
Gtf2a1l	G	T	17: 89,018,900 (GRCm39)	R328L	probably benign	Het
Hectd4	T	A	5: 121,491,600 (GRCm39)	F3679L	probably benign	Het
Itgb8	T	C	12: 119,166,190 (GRCm39)	I114V	probably benign	Het
Klf10	A	G	15: 38,297,326 (GRCm39)	V223A	possibly damaging	Het
Lyn	G	A	4: 3,780,959 (GRCm39)	R345H	probably damaging	Het
Med13l	T	A	5: 118,731,512 (GRCm39)	C63S	probably damaging	Het
Nlrp1a	T	C	11: 70,996,927 (GRCm39)	T960A	possibly damaging	Het
Ogfod1	C	T	8: 94,763,996 (GRCm39)	S27L	probably damaging	Het
Or4k51	T	A	2: 111,584,621 (GRCm39)	V9E	probably benign	Het
Pcdha1	A	G	18: 37,289,236 (GRCm39)	Y864C	probably damaging	Het
Pkd1	A	G	17: 24,793,586 (GRCm39)	K1758E	probably benign	Het
Polk	T	C	13: 96,620,652 (GRCm39)	E516G	probably benign	Het
Shroom3	G	T	5: 93,090,945 (GRCm39)	V1151F	probably damaging	Het
Slco5a1	C	T	1: 12,949,486 (GRCm39)	G635S	probably damaging	Het
Sptbn2	G	A	19: 4,784,166 (GRCm39)	R636Q	probably benign	Het
Tmem139	G	T	6: 42,240,364 (GRCm39)	C57F	possibly damaging	Het
Traf5	T	C	1: 191,729,926 (GRCm39)	N375S	probably benign	Het
Tti2	T	C	8: 31,645,823 (GRCm39)	V379A	probably benign	Het
Zfp106	T	C	2: 120,366,131 (GRCm39)	E92G	probably benign	Het

Other mutations in Gm16380

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL02207:Gm16380	APN	9	53,791,823 (GRCm39)	exon	noncoding transcript
R0386:Gm16380	UTSW	9	53,791,727 (GRCm39)	exon	noncoding transcript
R0398:Gm16380	UTSW	9	53,791,453 (GRCm39)	exon	noncoding transcript
R0512:Gm16380	UTSW	9	53,791,529 (GRCm39)	exon	noncoding transcript
R1419:Gm16380	UTSW	9	53,791,471 (GRCm39)	exon	noncoding transcript
R3697:Gm16380	UTSW	9	53,791,736 (GRCm39)	exon	noncoding transcript
R5128:Gm16380	UTSW	9	53,791,397 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- ATCTAGTGACGTGTGCTCG -3'
(R):5'- TCATGCACGATGAACAAGCG -3'

Sequencing Primer
(F):5'- TGTGTGATACCCGCTAC -3'
(R):5'- CTGAGCTTGGCACCATGTCAG -3'

Posted On

2014-10-30