Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00959:Vmn2r29'

27882

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r29

Ensembl Gene

ENSMUSG00000095730

Gene Name

vomeronasal 2, receptor 29

Synonyms

6430701C03Rik

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL00959

Quality Score

Status

Chromosome

Chromosomal Location

7234326-7250327 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 7244855 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Arginine at position 340 (W340R)

Ref Sequence

ENSEMBL: ENSMUSP00000131990 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000170922] [ENSMUST00000173842] [ENSMUST00000209325] [ENSMUST00000209833] [ENSMUST00000210333]

AlphaFold

L7N2D4

Predicted Effect

probably benign
Transcript: ENSMUST00000170922
AA Change: W340R

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)

SMART Domains

Protein: ENSMUSP00000131990
Gene: ENSMUSG00000095730
AA Change: W340R

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	73	469	2e-34	PFAM
Pfam:NCD3G	512	565	1.4e-20	PFAM
Pfam:7tm_3	598	833	2e-55	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000173842

Predicted Effect

probably benign
Transcript: ENSMUST00000209325

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000209613

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000209788

Predicted Effect

probably benign
Transcript: ENSMUST00000209833

Predicted Effect

probably benign
Transcript: ENSMUST00000210333

Predicted Effect

probably benign
Transcript: ENSMUST00000211433

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Alox12b	A	T	11: 69,057,069 (GRCm39)	H430L	probably damaging	Het
Aox4	G	T	1: 58,278,333 (GRCm39)	V443F	probably damaging	Het
Bmpr2	A	T	1: 59,854,474 (GRCm39)	I108F	possibly damaging	Het
Cflar	G	A	1: 58,768,321 (GRCm39)		probably null	Het
Chchd3	A	G	6: 32,945,188 (GRCm39)	V106A	probably benign	Het
Chl1	G	T	6: 103,686,211 (GRCm39)		probably null	Het
Clvs2	C	T	10: 33,404,459 (GRCm39)	M252I	probably benign	Het
Cntnap5a	T	A	1: 116,112,057 (GRCm39)	L449Q	probably benign	Het
Col6a2	T	A	10: 76,450,368 (GRCm39)	I188F	probably damaging	Het
Cyp2c55	A	G	19: 39,026,587 (GRCm39)	D398G	probably benign	Het
Dennd1b	T	C	1: 139,071,626 (GRCm39)		probably benign	Het
Dop1a	T	A	9: 86,369,484 (GRCm39)	Y106N	probably damaging	Het
Dpy19l1	A	T	9: 24,334,493 (GRCm39)		probably null	Het
Extl3	C	T	14: 65,314,361 (GRCm39)	V274I	probably benign	Het
Fras1	G	A	5: 96,929,140 (GRCm39)	R3848H	probably damaging	Het
Gm11437	A	C	11: 84,039,448 (GRCm39)		probably benign	Het
Gss	T	A	2: 155,423,871 (GRCm39)	D2V	probably damaging	Het
Hnrnpm	C	A	17: 33,868,876 (GRCm39)	R517L	probably damaging	Het
Ilvbl	G	A	10: 78,419,739 (GRCm39)	D548N	probably damaging	Het
Jmjd6	A	T	11: 116,733,202 (GRCm39)	D115E	possibly damaging	Het
Kidins220	T	A	12: 25,101,132 (GRCm39)	S1110R	possibly damaging	Het
Kmt2c	T	A	5: 25,481,227 (GRCm39)	I4784F	probably damaging	Het
Mrpl52	T	C	14: 54,664,494 (GRCm39)	V11A	possibly damaging	Het
Myo3b	A	G	2: 70,144,636 (GRCm39)	Y1036C	probably damaging	Het
Omp	T	C	7: 97,794,357 (GRCm39)	D90G	probably damaging	Het
Or6c2b	T	A	10: 128,947,893 (GRCm39)	M134L	probably benign	Het
Osmr	T	C	15: 6,854,086 (GRCm39)	I541V	probably benign	Het
Ppp2r1a	A	T	17: 21,181,840 (GRCm39)		probably benign	Het
Ptpn13	T	A	5: 103,665,437 (GRCm39)		probably null	Het
Rock2	C	A	12: 17,028,056 (GRCm39)	N1429K	probably benign	Het
Saxo4	A	T	19: 10,454,887 (GRCm39)		probably null	Het
Slc25a20	T	G	9: 108,559,198 (GRCm39)	M188R	possibly damaging	Het
Slc28a1	T	C	7: 80,818,816 (GRCm39)		probably benign	Het
Sult2a6	T	C	7: 13,988,634 (GRCm39)	Y42C	probably damaging	Het
Tgfb2	A	G	1: 186,436,784 (GRCm39)	V63A	probably benign	Het
Ugt2b38	A	T	5: 87,559,682 (GRCm39)	N403K	probably damaging	Het
Wnt5a	C	T	14: 28,244,866 (GRCm39)	T351M	probably damaging	Het

Other mutations in Vmn2r29

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02232:Vmn2r29	APN	7	7,244,810 (GRCm39)	missense	probably damaging	1.00
R2262:Vmn2r29	UTSW	7	7,243,085 (GRCm39)	missense	possibly damaging	0.49
R3775:Vmn2r29	UTSW	7	7,243,011 (GRCm39)	missense	probably damaging	1.00
R6173:Vmn2r29	UTSW	7	7,234,369 (GRCm39)	missense	probably benign	0.13
R6604:Vmn2r29	UTSW	7	7,234,858 (GRCm39)	missense	probably damaging	1.00
R6747:Vmn2r29	UTSW	7	7,234,421 (GRCm39)	missense	probably benign	0.00
R6878:Vmn2r29	UTSW	7	7,244,863 (GRCm39)	missense	probably benign	0.05
R6899:Vmn2r29	UTSW	7	7,244,641 (GRCm39)	missense	probably damaging	1.00
R7533:Vmn2r29	UTSW	7	7,244,656 (GRCm39)	missense	probably damaging	1.00
R7578:Vmn2r29	UTSW	7	7,234,441 (GRCm39)	missense	probably damaging	0.99
R7703:Vmn2r29	UTSW	7	7,234,864 (GRCm39)	missense	probably benign	0.01
R7917:Vmn2r29	UTSW	7	7,234,727 (GRCm39)	missense	probably damaging	1.00
R8325:Vmn2r29	UTSW	7	7,244,941 (GRCm39)	missense	probably damaging	0.98
R8335:Vmn2r29	UTSW	7	7,234,445 (GRCm39)	missense	probably damaging	1.00
R8418:Vmn2r29	UTSW	7	7,244,939 (GRCm39)	missense	probably benign
R9562:Vmn2r29	UTSW	7	7,244,855 (GRCm39)	missense	probably benign	0.00
R9565:Vmn2r29	UTSW	7	7,244,855 (GRCm39)	missense	probably benign	0.00
R9734:Vmn2r29	UTSW	7	7,234,492 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-04-17