Incidental Mutation 'IGL02337:Ceacam11'
ID288899
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ceacam11
Ensembl Gene ENSMUSG00000030368
Gene Namecarcinoembryonic antigen-related cell adhesion molecule 11
SynonymsCeacam11-C1, Ceacam11-C3, Ceacam11-C4, 1600015D01Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.034) question?
Stock #IGL02337
Quality Score
Status
Chromosome7
Chromosomal Location17972124-17978556 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 17973625 bp
ZygosityHeterozygous
Amino Acid Change Serine to Arginine at position 111 (S111R)
Ref Sequence ENSEMBL: ENSMUSP00000092393 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000094799]
Predicted Effect probably benign
Transcript: ENSMUST00000094799
AA Change: S111R

PolyPhen 2 Score 0.094 (Sensitivity: 0.93; Specificity: 0.85)
SMART Domains Protein: ENSMUSP00000092393
Gene: ENSMUSG00000030368
AA Change: S111R

DomainStartEndE-ValueType
IG_like 40 141 8.06e0 SMART
IG_like 160 261 8.5e0 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aaas A G 15: 102,339,227 V403A probably benign Het
Afm A G 5: 90,547,911 T426A probably benign Het
Atp8a2 T C 14: 59,998,002 D697G probably benign Het
Barhl1 G T 2: 28,911,419 S204R probably damaging Het
Cenpe A G 3: 135,220,276 probably benign Het
Cnot11 G A 1: 39,544,883 probably benign Het
Ctc1 A G 11: 69,026,131 T284A probably damaging Het
Ephb3 A G 16: 21,221,503 probably null Het
Fsip1 T A 2: 118,251,714 K80* probably null Het
Gaa G T 11: 119,277,603 G220C probably damaging Het
Gna15 T C 10: 81,514,410 S53G probably damaging Het
Hfm1 A T 5: 106,904,267 M321K possibly damaging Het
Hgfac C A 5: 35,042,378 T68K probably benign Het
Hmgxb4 C T 8: 74,999,631 R35W probably damaging Het
Itfg2 T C 6: 128,413,570 D184G probably benign Het
Kirrel G A 3: 87,089,212 T360I possibly damaging Het
Lrp1 T C 10: 127,576,887 Q1240R possibly damaging Het
Lrrk1 G T 7: 66,279,416 T1156N possibly damaging Het
Olfm1 A G 2: 28,229,685 Y429C probably damaging Het
Olfr1093 T A 2: 86,786,174 M148K probably damaging Het
Olfr1283 T G 2: 111,369,151 V173G probably benign Het
Pafah1b2 C T 9: 45,972,989 V122I probably benign Het
Pdcd1 T C 1: 94,040,857 T151A probably benign Het
Pkd1l1 T C 11: 8,942,079 S697G probably damaging Het
Rgs12 T A 5: 35,020,353 F96I probably damaging Het
Sptbn4 T C 7: 27,428,247 D176G probably benign Het
Tarbp2 C A 15: 102,521,993 Q148K probably damaging Het
Txk T C 5: 72,707,546 R329G possibly damaging Het
Unc79 T A 12: 103,156,446 probably benign Het
Vmn1r73 C A 7: 11,756,713 P153T possibly damaging Het
Zeb2 G A 2: 44,997,230 T605I probably damaging Het
Zfp654 A G 16: 64,785,149 S897P probably benign Het
Other mutations in Ceacam11
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00844:Ceacam11 APN 7 17973670 missense possibly damaging 0.82
IGL01161:Ceacam11 APN 7 17978510 missense possibly damaging 0.95
IGL01744:Ceacam11 APN 7 17973398 missense possibly damaging 0.95
IGL02052:Ceacam11 APN 7 17973623 missense probably benign 0.09
IGL03079:Ceacam11 APN 7 17978436 missense probably benign 0.02
R1902:Ceacam11 UTSW 7 17975327 missense probably benign 0.05
R2204:Ceacam11 UTSW 7 17975348 missense possibly damaging 0.92
R2851:Ceacam11 UTSW 7 17978526 missense probably benign 0.01
R3237:Ceacam11 UTSW 7 17973454 missense probably benign 0.02
R4786:Ceacam11 UTSW 7 17972314 critical splice donor site probably null
R8097:Ceacam11 UTSW 7 17975530 nonsense probably null
Posted On2015-04-16