Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02337:Ceacam11'

288899

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ceacam11

Ensembl Gene

ENSMUSG00000030368

Gene Name

CEA cell adhesion molecule 11

Synonyms

Ceacam11-C1, Ceacam11-C3, Ceacam11-C4, 1600015D01Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.050) question?

Stock #

IGL02337

Quality Score

Status

Chromosome

Chromosomal Location

17706092-17712481 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 17707550 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Arginine at position 111 (S111R)

Ref Sequence

ENSEMBL: ENSMUSP00000092393 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094799]

AlphaFold

Q9D0Z8

Predicted Effect

probably benign
Transcript: ENSMUST00000094799
AA Change: S111R

PolyPhen 2 Score 0.094 (Sensitivity: 0.93; Specificity: 0.85)

SMART Domains

Protein: ENSMUSP00000092393
Gene: ENSMUSG00000030368
AA Change: S111R

Domain	Start	End	E-Value	Type
IG_like	40	141	8.06e0	SMART
IG_like	160	261	8.5e0	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aaas	A	G	15: 102,247,662 (GRCm39)	V403A	probably benign	Het
Afm	A	G	5: 90,695,770 (GRCm39)	T426A	probably benign	Het
Atp8a2	T	C	14: 60,235,451 (GRCm39)	D697G	probably benign	Het
Barhl1	G	T	2: 28,801,431 (GRCm39)	S204R	probably damaging	Het
Cenpe	A	G	3: 134,926,037 (GRCm39)		probably benign	Het
Cnot11	G	A	1: 39,583,964 (GRCm39)		probably benign	Het
Ctc1	A	G	11: 68,916,957 (GRCm39)	T284A	probably damaging	Het
Ephb3	A	G	16: 21,040,253 (GRCm39)		probably null	Het
Fsip1	T	A	2: 118,082,195 (GRCm39)	K80*	probably null	Het
Gaa	G	T	11: 119,168,429 (GRCm39)	G220C	probably damaging	Het
Gna15	T	C	10: 81,350,244 (GRCm39)	S53G	probably damaging	Het
Hfm1	A	T	5: 107,052,133 (GRCm39)	M321K	possibly damaging	Het
Hgfac	C	A	5: 35,199,722 (GRCm39)	T68K	probably benign	Het
Hmgxb4	C	T	8: 75,726,259 (GRCm39)	R35W	probably damaging	Het
Itfg2	T	C	6: 128,390,533 (GRCm39)	D184G	probably benign	Het
Kirrel1	G	A	3: 86,996,519 (GRCm39)	T360I	possibly damaging	Het
Lrp1	T	C	10: 127,412,756 (GRCm39)	Q1240R	possibly damaging	Het
Lrrk1	G	T	7: 65,929,164 (GRCm39)	T1156N	possibly damaging	Het
Olfm1	A	G	2: 28,119,697 (GRCm39)	Y429C	probably damaging	Het
Or4k77	T	G	2: 111,199,496 (GRCm39)	V173G	probably benign	Het
Or5t5	T	A	2: 86,616,518 (GRCm39)	M148K	probably damaging	Het
Pafah1b2	C	T	9: 45,884,287 (GRCm39)	V122I	probably benign	Het
Pdcd1	T	C	1: 93,968,582 (GRCm39)	T151A	probably benign	Het
Pkd1l1	T	C	11: 8,892,079 (GRCm39)	S697G	probably damaging	Het
Rgs12	T	A	5: 35,177,697 (GRCm39)	F96I	probably damaging	Het
Sptbn4	T	C	7: 27,127,672 (GRCm39)	D176G	probably benign	Het
Tarbp2	C	A	15: 102,430,428 (GRCm39)	Q148K	probably damaging	Het
Txk	T	C	5: 72,864,889 (GRCm39)	R329G	possibly damaging	Het
Unc79	T	A	12: 103,122,705 (GRCm39)		probably benign	Het
Vmn1r73	C	A	7: 11,490,640 (GRCm39)	P153T	possibly damaging	Het
Zeb2	G	A	2: 44,887,242 (GRCm39)	T605I	probably damaging	Het
Zfp654	A	G	16: 64,605,512 (GRCm39)	S897P	probably benign	Het

Other mutations in Ceacam11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00844:Ceacam11	APN	7	17,707,595 (GRCm39)	missense	possibly damaging	0.82
IGL01161:Ceacam11	APN	7	17,712,435 (GRCm39)	missense	possibly damaging	0.95
IGL01744:Ceacam11	APN	7	17,707,323 (GRCm39)	missense	possibly damaging	0.95
IGL02052:Ceacam11	APN	7	17,707,548 (GRCm39)	missense	probably benign	0.09
IGL03079:Ceacam11	APN	7	17,712,361 (GRCm39)	missense	probably benign	0.02
R1902:Ceacam11	UTSW	7	17,709,252 (GRCm39)	missense	probably benign	0.05
R2204:Ceacam11	UTSW	7	17,709,273 (GRCm39)	missense	possibly damaging	0.92
R2851:Ceacam11	UTSW	7	17,712,451 (GRCm39)	missense	probably benign	0.01
R3237:Ceacam11	UTSW	7	17,707,379 (GRCm39)	missense	probably benign	0.02
R4786:Ceacam11	UTSW	7	17,706,239 (GRCm39)	critical splice donor site	probably null
R8097:Ceacam11	UTSW	7	17,709,455 (GRCm39)	nonsense	probably null
R8109:Ceacam11	UTSW	7	17,709,243 (GRCm39)	missense	probably benign	0.01
R8476:Ceacam11	UTSW	7	17,707,618 (GRCm39)	missense	probably benign	0.03
R8878:Ceacam11	UTSW	7	17,709,536 (GRCm39)	missense	probably benign	0.01
R9492:Ceacam11	UTSW	7	17,709,468 (GRCm39)	missense	probably benign	0.00

Posted On

2015-04-16