Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02963:Vmn1r167'

365415

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r167

Ensembl Gene

ENSMUSG00000090715

Gene Name

vomeronasal 1 receptor 167

Synonyms

Gm6279

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.052) question?

Stock #

IGL02963

Quality Score

Status

Chromosome

Chromosomal Location

23503646-23507206 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 23505550 bp

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 14 (S14P)

Ref Sequence

ENSEMBL: ENSMUSP00000153774 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000164527] [ENSMUST00000227713]

Predicted Effect

possibly damaging
Transcript: ENSMUST00000164527
AA Change: S14P

PolyPhen 2 Score 0.598 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000129193
Gene: ENSMUSG00000090715
AA Change: S14P

Domain	Start	End	E-Value	Type
Pfam:TAS2R	19	307	1.5e-13	PFAM
Pfam:7tm_1	41	299	3.8e-6	PFAM
Pfam:V1R	52	306	2.1e-18	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000227713
AA Change: S14P

PolyPhen 2 Score 0.598 (Sensitivity: 0.87; Specificity: 0.91)

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca3	T	A	17: 24,384,529	L565Q	probably damaging	Het
Ap1b1	G	T	11: 5,033,738	A664S	possibly damaging	Het
Arhgap44	A	T	11: 65,031,663	I348N	probably damaging	Het
Bahcc1	T	C	11: 120,274,932	S1005P	possibly damaging	Het
Cdh20	T	A	1: 104,934,098	M1K	probably null	Het
Cpsf3	T	C	12: 21,302,422	S387P	probably damaging	Het
Cyp2j6	T	C	4: 96,518,184	E450G	probably damaging	Het
Cyr61	A	G	3: 145,647,875	Y311H	probably damaging	Het
Dusp13	T	C	14: 21,733,807	T147A	possibly damaging	Het
Eif3c	T	C	7: 126,556,820	T493A	probably benign	Het
Ell2	T	C	13: 75,769,643	V564A	possibly damaging	Het
Gm4788	G	A	1: 139,731,596	Q732*	probably null	Het
Gtf2ird1	T	G	5: 134,389,687	E478D	probably benign	Het
Gys2	A	T	6: 142,449,428		probably null	Het
H2-T3	T	C	17: 36,189,634	T104A	probably damaging	Het
Herc1	T	C	9: 66,388,823	S567P	probably damaging	Het
Kcnq3	A	T	15: 66,285,826		probably benign	Het
Kdm7a	T	C	6: 39,143,230	H935R	probably damaging	Het
Lcat	A	T	8: 105,939,956	F311L	probably damaging	Het
Manf	A	G	9: 106,891,139	S49P	possibly damaging	Het
Med25	T	C	7: 44,892,256	K37E	probably damaging	Het
Ms4a4b	T	A	19: 11,454,698	I61K	probably damaging	Het
Muc5b	T	C	7: 141,864,264	I3649T	probably damaging	Het
Myo18a	T	G	11: 77,842,018		probably benign	Het
Ncoa4	T	C	14: 32,176,509	C429R	probably damaging	Het
Olfr113	A	G	17: 37,574,854	S190P	probably benign	Het
Pigk	G	T	3: 152,766,461	E337*	probably null	Het
Pigz	A	T	16: 31,944,535	Y137F	probably damaging	Het
Ppp1r12b	A	G	1: 134,886,548	L339P	probably damaging	Het
Rasa2	C	A	9: 96,570,785	L349F	probably damaging	Het
Reep4	A	G	14: 70,547,970	S186G	possibly damaging	Het
Rfx7	A	G	9: 72,617,616	K696R	probably benign	Het
Rnf220	A	G	4: 117,490,192	F8L	probably damaging	Het
Rprm	T	C	2: 54,085,214	T31A	probably benign	Het
Sez6	T	A	11: 77,962,949	L148Q	possibly damaging	Het
Sh2d6	C	T	6: 72,517,601	V96I	probably benign	Het
Slc16a9	G	T	10: 70,267,136	V81F	probably damaging	Het
Slc9a9	T	A	9: 95,020,714		probably null	Het
Sppl3	T	A	5: 115,061,603	L22Q	probably damaging	Het
Ssc5d	T	C	7: 4,944,327	S1227P	probably benign	Het
Tbc1d1	T	A	5: 64,264,366	V238E	probably damaging	Het
Tmco6	G	A	18: 36,738,745		probably null	Het
Tyr	A	G	7: 87,483,997	V287A	probably benign	Het
Uvrag	A	T	7: 98,906,490		probably null	Het
Vmn1r171	A	G	7: 23,632,688	T113A	possibly damaging	Het
Wnk4	A	G	11: 101,276,213		probably benign	Het
Zan	T	C	5: 137,456,250	T1431A	unknown	Het

Other mutations in Vmn1r167

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02137:Vmn1r167	APN	7	23505439	missense	probably damaging	0.98
IGL02261:Vmn1r167	APN	7	23504836	missense	probably benign	0.17
R0054:Vmn1r167	UTSW	7	23504909	missense	possibly damaging	0.89
R0555:Vmn1r167	UTSW	7	23505087	missense	probably damaging	1.00
R0766:Vmn1r167	UTSW	7	23505123	missense	probably benign	0.01
R1312:Vmn1r167	UTSW	7	23505123	missense	probably benign	0.01
R1464:Vmn1r167	UTSW	7	23505256	missense	possibly damaging	0.62
R1464:Vmn1r167	UTSW	7	23505256	missense	possibly damaging	0.62
R1532:Vmn1r167	UTSW	7	23504779	missense	probably benign	0.01
R1937:Vmn1r167	UTSW	7	23505027	missense	probably benign	0.25
R2162:Vmn1r167	UTSW	7	23504799	missense	possibly damaging	0.91
R4639:Vmn1r167	UTSW	7	23505586	missense	probably benign	0.00
R4661:Vmn1r167	UTSW	7	23504692	missense	probably damaging	1.00
R4845:Vmn1r167	UTSW	7	23504733	missense	probably benign	0.01
R4868:Vmn1r167	UTSW	7	23504736	missense	probably benign
R4993:Vmn1r167	UTSW	7	23505228	missense	probably damaging	1.00
R5693:Vmn1r167	UTSW	7	23505221	nonsense	probably null
R6622:Vmn1r167	UTSW	7	23505589	start codon destroyed	probably null
R7800:Vmn1r167	UTSW	7	23504644	makesense	probably null
R8297:Vmn1r167	UTSW	7	23504790	missense	probably damaging	1.00
R8365:Vmn1r167	UTSW	7	23504775	missense	probably benign	0.03
R8411:Vmn1r167	UTSW	7	23505556	missense	possibly damaging	0.86

Posted On

2015-12-18