Mutagenetix > Incidental Mutation

Incidental Mutation 'R4862:Zfa-ps'

374597

Institutional Source

Beutler Lab

Gene Symbol

Zfa-ps

Ensembl Gene

ENSMUSG00000049576

Gene Name

zinc finger protein, autosomal, pseudogene

Synonyms

Zfa

MMRRC Submission

043260-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.218) question?

Stock #

R4862 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

52418416-52421835 bp(-) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

G to T at 52419192 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000180526

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000180673

Meta Mutation Damage Score

0.6907

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.2%
20x: 95.0%

Validation Efficiency

95% (40/42)

Allele List at MGI

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acox3	A	G	5: 35,747,083 (GRCm39)	T167A	probably benign	Het
Aox1	T	G	1: 58,134,316 (GRCm39)	D1096E	probably damaging	Het
Arid4a	A	T	12: 71,122,721 (GRCm39)	D1034V	probably damaging	Het
Ccdc168	G	A	1: 44,097,178 (GRCm39)	P1307S	possibly damaging	Het
Chaf1b	T	A	16: 93,684,022 (GRCm39)	L91Q	probably damaging	Het
Copb2	G	T	9: 98,463,320 (GRCm39)	D512Y	probably damaging	Het
Daam1	A	G	12: 71,988,981 (GRCm39)	E127G	unknown	Het
Dhx16	A	G	17: 36,194,154 (GRCm39)	I422V	probably benign	Het
Dnah6	C	T	6: 73,098,771 (GRCm39)	V2043I	probably damaging	Het
Dnase1l1	C	T	X: 73,320,644 (GRCm39)		probably null	Het
Dync2h1	A	G	9: 7,147,717 (GRCm39)	V971A	probably benign	Het
Elapor1	A	G	3: 108,375,149 (GRCm39)	S573P	probably benign	Het
Elmo1	A	G	13: 20,633,682 (GRCm39)	H448R	probably benign	Het
Fndc1	A	T	17: 7,988,567 (GRCm39)	V1165D	unknown	Het
Hapln1	G	A	13: 89,749,571 (GRCm39)	G39S	possibly damaging	Het
Igkv6-13	C	A	6: 70,434,765 (GRCm39)	V27L	probably benign	Het
Krt28	A	T	11: 99,255,936 (GRCm39)	I441N	possibly damaging	Het
Lgr5	A	T	10: 115,298,669 (GRCm39)	D286E	probably damaging	Het
Mapkap1	A	G	2: 34,513,442 (GRCm39)	Y448C	probably damaging	Het
Or2f1	T	C	6: 42,721,489 (GRCm39)	Y173H	possibly damaging	Het
Or5t9	T	A	2: 86,659,876 (GRCm39)	V260E	probably damaging	Het
Ppt1	A	C	4: 122,738,242 (GRCm39)	N89T	probably damaging	Het
Prss3b	T	G	6: 41,009,345 (GRCm39)	D163A	possibly damaging	Het
Ptgs1	G	T	2: 36,127,267 (GRCm39)	R51L	probably damaging	Het
Slc47a2	A	G	11: 61,204,520 (GRCm39)	F277S	possibly damaging	Het
Smcr8	A	G	11: 60,668,897 (GRCm39)	E15G	probably benign	Het
Tbce	A	G	13: 14,173,004 (GRCm39)	S476P	possibly damaging	Het
Tmem131l	A	T	3: 83,805,517 (GRCm39)		probably benign	Het
Unc5c	T	C	3: 141,495,534 (GRCm39)	Y468H	probably damaging	Het
Ush1c	A	T	7: 45,878,664 (GRCm39)	L117H	probably damaging	Het
Wdfy4	A	G	14: 32,822,860 (GRCm39)		probably null	Het
Zfat	C	A	15: 68,051,959 (GRCm39)	A605S	probably benign	Het
Zfp853	T	A	5: 143,275,416 (GRCm39)	Q68L	unknown	Het
Zfyve16	G	A	13: 92,644,764 (GRCm39)	T1146I	probably damaging	Het

Other mutations in Zfa-ps

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL00960:Zfa-ps	APN	10	52,420,043 (GRCm39)	exon	noncoding transcript
R0057:Zfa-ps	UTSW	10	52,421,202 (GRCm39)	exon	noncoding transcript
R0057:Zfa-ps	UTSW	10	52,421,202 (GRCm39)	exon	noncoding transcript
R1159:Zfa-ps	UTSW	10	52,419,654 (GRCm39)	exon	noncoding transcript
R2145:Zfa-ps	UTSW	10	52,419,373 (GRCm39)	exon	noncoding transcript
R2290:Zfa-ps	UTSW	10	52,421,112 (GRCm39)	exon	noncoding transcript
R2509:Zfa-ps	UTSW	10	52,420,339 (GRCm39)	exon	noncoding transcript
R3738:Zfa-ps	UTSW	10	52,420,636 (GRCm39)	exon	noncoding transcript
R4035:Zfa-ps	UTSW	10	52,420,636 (GRCm39)	exon	noncoding transcript
R4290:Zfa-ps	UTSW	10	52,419,807 (GRCm39)	exon	noncoding transcript
R4545:Zfa-ps	UTSW	10	52,421,032 (GRCm39)	exon	noncoding transcript
R5135:Zfa-ps	UTSW	10	52,419,118 (GRCm39)	exon	noncoding transcript
R5270:Zfa-ps	UTSW	10	52,419,552 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- GTATGTGAACAAGACTGATTGGCTTC -3'
(R):5'- GATCCGTTTGTACTAAGTCGCC -3'

Sequencing Primer
(F):5'- GAACAAGACTGATTGGCTTCTAAATG -3'
(R):5'- TCGGTTCATACAAAGGACCTTC -3'

Posted On

2016-03-17