Incidental Mutation 'IGL03103:Olfr913'
ID418817
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Olfr913
Ensembl Gene ENSMUSG00000059189
Gene Nameolfactory receptor 913
SynonymsMOR165-9P, GA_x6K02T2PVTD-32296575-32297513, MOR165-10
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.053) question?
Stock #IGL03103
Quality Score
Status
Chromosome9
Chromosomal Location38592759-38596283 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 38594527 bp
ZygosityHeterozygous
Amino Acid Change Tyrosine to Cysteine at position 102 (Y102C)
Ref Sequence ENSEMBL: ENSMUSP00000079876 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000081095]
Predicted Effect probably damaging
Transcript: ENSMUST00000081095
AA Change: Y102C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000079876
Gene: ENSMUSG00000059189
AA Change: Y102C

DomainStartEndE-ValueType
Pfam:7tm_4 31 308 2.6e-49 PFAM
Pfam:7tm_1 41 290 3.9e-23 PFAM
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 29 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ccdc129 A G 6: 55,968,159 T622A possibly damaging Het
Cdc27 A T 11: 104,512,980 F652Y probably benign Het
Cntn5 T C 9: 9,972,812 probably benign Het
Ctsc A G 7: 88,309,805 N431S probably benign Het
Ddi2 A G 4: 141,703,168 M235T probably damaging Het
Dgkg G A 16: 22,580,525 P220S probably damaging Het
Gpr180 A T 14: 118,139,763 I59F possibly damaging Het
Haspin A T 11: 73,136,700 V521D probably damaging Het
Kif16b G T 2: 142,862,488 T57N probably damaging Het
Lmbr1 A G 5: 29,235,016 F422S probably damaging Het
Lpcat2b A T 5: 107,433,548 N248Y probably damaging Het
Lrch3 T C 16: 32,952,137 V163A probably damaging Het
Lrrc49 A G 9: 60,685,033 probably null Het
Mon2 T A 10: 123,030,103 probably benign Het
Mroh4 T C 15: 74,616,159 S374G possibly damaging Het
Nr1h3 T A 2: 91,192,015 K89N probably damaging Het
Olfr1209 A T 2: 88,910,178 S72T probably benign Het
Olfr692 A G 7: 105,368,578 D75G probably damaging Het
Phldb3 C T 7: 24,624,176 P445L possibly damaging Het
Pstpip1 G T 9: 56,114,308 V39L possibly damaging Het
Sbf1 A T 15: 89,293,947 L1560Q probably damaging Het
Sco1 C T 11: 67,055,742 Q114* probably null Het
Slc29a4 A G 5: 142,712,080 H96R probably damaging Het
Slitrk6 A G 14: 110,749,941 L778P probably benign Het
Tas2r110 A G 6: 132,868,480 Q158R probably benign Het
Tle3 A G 9: 61,393,242 I92V possibly damaging Het
Ttn T A 2: 76,748,922 M15549L possibly damaging Het
Urb2 T G 8: 124,029,752 S733A probably benign Het
Vcl T C 14: 21,024,280 W912R probably damaging Het
Other mutations in Olfr913
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01092:Olfr913 APN 9 38594905 missense probably damaging 0.98
IGL02028:Olfr913 APN 9 38594419 nonsense probably null
IGL02256:Olfr913 APN 9 38594544 missense probably benign 0.01
IGL03297:Olfr913 APN 9 38594525 missense probably benign 0.01
R2152:Olfr913 UTSW 9 38594411 missense probably damaging 1.00
R2153:Olfr913 UTSW 9 38594411 missense probably damaging 1.00
R2154:Olfr913 UTSW 9 38594411 missense probably damaging 1.00
R3176:Olfr913 UTSW 9 38594643 missense probably damaging 1.00
R3276:Olfr913 UTSW 9 38594643 missense probably damaging 1.00
R4985:Olfr913 UTSW 9 38594362 missense possibly damaging 0.88
R5043:Olfr913 UTSW 9 38594841 missense probably damaging 1.00
R5871:Olfr913 UTSW 9 38594332 missense possibly damaging 0.53
R6106:Olfr913 UTSW 9 38594956 missense probably benign 0.11
R6583:Olfr913 UTSW 9 38594964 missense possibly damaging 0.79
R6823:Olfr913 UTSW 9 38594905 missense possibly damaging 0.89
R7472:Olfr913 UTSW 9 38594904 missense probably benign 0.10
R7912:Olfr913 UTSW 9 38595150 missense probably benign 0.25
R8036:Olfr913 UTSW 9 38594890 missense probably benign 0.00
R8182:Olfr913 UTSW 9 38594544 missense probably benign 0.01
R8390:Olfr913 UTSW 9 38594591 nonsense probably null
Z1177:Olfr913 UTSW 9 38594289 missense probably damaging 1.00
Posted On2016-08-02