Incidental Mutation 'R1484:Cep295'
| ID |
163323 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cep295
|
| Ensembl Gene |
ENSMUSG00000046111 |
| Gene Name |
centrosomal protein 295 |
| Synonyms |
5830418K08Rik, LOC382128 |
| MMRRC Submission |
039537-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.952)
|
| Stock # |
R1484 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
15228211-15269084 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 15246080 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Arginine
at position 744
(I744R)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000098979]
[ENSMUST00000161132]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000058041
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000059410
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000066038
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098979
AA Change: I792R
PolyPhen 2
Score 0.158 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000096578
Gene: ENSMUSG00000046111
AA Change: I792R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
159 |
175 |
N/A |
INTRINSIC |
|
coiled coil region
|
258 |
288 |
N/A |
INTRINSIC |
|
coiled coil region
|
536 |
583 |
N/A |
INTRINSIC |
|
coiled coil region
|
861 |
889 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
890 |
1104 |
6.8e-5 |
PROSPERO |
|
internal_repeat_1
|
1277 |
1489 |
6.8e-5 |
PROSPERO |
|
low complexity region
|
1537 |
1548 |
N/A |
INTRINSIC |
|
low complexity region
|
1611 |
1625 |
N/A |
INTRINSIC |
|
coiled coil region
|
1707 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
2003 |
2018 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160946
|
| SMART Domains |
Protein: ENSMUSP00000125494
Gene: ENSMUSG00000046111
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
92 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
293 |
N/A |
INTRINSIC |
|
low complexity region
|
356 |
370 |
N/A |
INTRINSIC |
|
coiled coil region
|
451 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
828 |
843 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000161132
AA Change: I792R
PolyPhen 2
Score 0.974 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000123788
Gene: ENSMUSG00000046111
AA Change: I792R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
111 |
127 |
N/A |
INTRINSIC |
|
coiled coil region
|
210 |
240 |
N/A |
INTRINSIC |
|
coiled coil region
|
488 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
813 |
841 |
N/A |
INTRINSIC |
|
coiled coil region
|
1300 |
1327 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1500 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1577 |
N/A |
INTRINSIC |
|
coiled coil region
|
1659 |
1688 |
N/A |
INTRINSIC |
|
low complexity region
|
2035 |
2050 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000161795
AA Change: I744R
PolyPhen 2
Score 0.986 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000125035
Gene: ENSMUSG00000046111
AA Change: I744R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
111 |
127 |
N/A |
INTRINSIC |
|
coiled coil region
|
210 |
240 |
N/A |
INTRINSIC |
|
coiled coil region
|
488 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
813 |
841 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
842 |
1056 |
7.14e-5 |
PROSPERO |
|
internal_repeat_1
|
1229 |
1441 |
7.14e-5 |
PROSPERO |
|
low complexity region
|
1489 |
1500 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1577 |
N/A |
INTRINSIC |
|
coiled coil region
|
1659 |
1688 |
N/A |
INTRINSIC |
|
low complexity region
|
1955 |
1970 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162264
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.4%
|
| Validation Efficiency |
97% (85/88) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930584F24Rik |
A |
T |
5: 26,684,776 (GRCm39) |
|
noncoding transcript |
Het |
| Acvr1 |
A |
T |
2: 58,369,901 (GRCm39) |
V36E |
probably damaging |
Het |
| Aldh4a1 |
A |
G |
4: 139,370,758 (GRCm39) |
I414V |
probably benign |
Het |
| Alox5 |
C |
T |
6: 116,431,128 (GRCm39) |
C100Y |
probably damaging |
Het |
| Ano5 |
T |
A |
7: 51,216,068 (GRCm39) |
D348E |
probably damaging |
Het |
| Arhgap30 |
G |
A |
1: 171,230,839 (GRCm39) |
V199M |
probably damaging |
Het |
| Arl13b |
T |
A |
16: 62,626,999 (GRCm39) |
Q234L |
probably benign |
Het |
| Atxn1 |
C |
A |
13: 45,711,052 (GRCm39) |
E627* |
probably null |
Het |
| Bend3 |
T |
C |
10: 43,386,197 (GRCm39) |
F197L |
probably benign |
Het |
| Brca1 |
A |
T |
11: 101,420,638 (GRCm39) |
V190E |
possibly damaging |
Het |
| Brpf1 |
T |
C |
6: 113,292,096 (GRCm39) |
W381R |
probably damaging |
Het |
| Brwd1 |
A |
C |
16: 95,829,491 (GRCm39) |
|
probably null |
Het |
| C1s2 |
T |
C |
6: 124,602,604 (GRCm39) |
I530V |
possibly damaging |
Het |
| C2cd3 |
C |
T |
7: 100,089,397 (GRCm39) |
R1638W |
probably damaging |
Het |
| Capns1 |
T |
A |
7: 29,893,511 (GRCm39) |
|
probably benign |
Het |
| Cd109 |
CATTTATTTATTTATTTATTTATTTATTTATTTAT |
CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT |
9: 78,619,782 (GRCm39) |
|
probably benign |
Het |
| Cep126 |
G |
A |
9: 8,100,554 (GRCm39) |
T660I |
possibly damaging |
Het |
| Chd3 |
T |
C |
11: 69,250,725 (GRCm39) |
E668G |
probably benign |
Het |
| Chek2 |
A |
G |
5: 110,996,553 (GRCm39) |
T172A |
probably damaging |
Het |
| Col6a4 |
A |
G |
9: 105,890,501 (GRCm39) |
|
probably null |
Het |
| Coq3 |
G |
A |
4: 21,900,291 (GRCm39) |
V173I |
probably benign |
Het |
| Cyp4x1 |
A |
T |
4: 114,970,098 (GRCm39) |
I343N |
probably damaging |
Het |
| Dnah7b |
T |
A |
1: 46,176,703 (GRCm39) |
D774E |
probably benign |
Het |
| Dnai3 |
T |
C |
3: 145,802,996 (GRCm39) |
D65G |
probably benign |
Het |
| Ecm1 |
G |
A |
3: 95,643,275 (GRCm39) |
R342C |
probably damaging |
Het |
| Esrra |
T |
C |
19: 6,890,197 (GRCm39) |
Y209C |
probably damaging |
Het |
| Gpr149 |
A |
T |
3: 62,502,592 (GRCm39) |
D421E |
probably benign |
Het |
| Gpr15 |
T |
C |
16: 58,538,937 (GRCm39) |
N51D |
probably damaging |
Het |
| Gpr156 |
T |
C |
16: 37,812,558 (GRCm39) |
V298A |
probably damaging |
Het |
| Hmcn2 |
G |
A |
2: 31,236,507 (GRCm39) |
G350D |
probably damaging |
Het |
| Ifih1 |
A |
T |
2: 62,440,902 (GRCm39) |
N421K |
probably benign |
Het |
| Ilvbl |
C |
A |
10: 78,412,564 (GRCm39) |
T95K |
probably damaging |
Het |
| Itgb4 |
T |
A |
11: 115,890,625 (GRCm39) |
D1104E |
probably benign |
Het |
| Katnip |
C |
A |
7: 125,415,743 (GRCm39) |
|
probably benign |
Het |
| Lipf |
A |
T |
19: 33,942,180 (GRCm39) |
M37L |
probably benign |
Het |
| Lyst |
T |
A |
13: 13,852,775 (GRCm39) |
N2258K |
probably benign |
Het |
| Moxd1 |
A |
G |
10: 24,099,758 (GRCm39) |
Y86C |
probably damaging |
Het |
| Muc5ac |
T |
C |
7: 141,367,629 (GRCm39) |
|
probably null |
Het |
| Myo16 |
G |
A |
8: 10,610,145 (GRCm39) |
R1162H |
probably damaging |
Het |
| Myo5c |
A |
T |
9: 75,208,092 (GRCm39) |
N1609Y |
probably damaging |
Het |
| Nbeal1 |
T |
C |
1: 60,240,098 (GRCm39) |
F155L |
probably damaging |
Het |
| Nek4 |
A |
T |
14: 30,704,290 (GRCm39) |
M602L |
possibly damaging |
Het |
| Nek9 |
A |
G |
12: 85,348,622 (GRCm39) |
S971P |
probably damaging |
Het |
| Nfya |
A |
T |
17: 48,700,570 (GRCm39) |
|
probably benign |
Het |
| Nrxn3 |
A |
T |
12: 89,221,547 (GRCm39) |
N442I |
probably damaging |
Het |
| Nup42 |
A |
C |
5: 24,383,075 (GRCm39) |
K200N |
probably benign |
Het |
| Or1e26 |
T |
A |
11: 73,480,187 (GRCm39) |
I126L |
possibly damaging |
Het |
| Or4c111 |
G |
A |
2: 88,843,713 (GRCm39) |
R232* |
probably null |
Het |
| Or7g32 |
G |
A |
9: 19,389,423 (GRCm39) |
T38I |
probably damaging |
Het |
| Pcdh15 |
T |
A |
10: 74,126,833 (GRCm39) |
I304N |
probably damaging |
Het |
| Pigo |
G |
C |
4: 43,024,779 (GRCm39) |
P107A |
probably damaging |
Het |
| Plce1 |
C |
T |
19: 38,693,783 (GRCm39) |
Q769* |
probably null |
Het |
| Plin2 |
C |
T |
4: 86,575,481 (GRCm39) |
R356H |
probably benign |
Het |
| Ppp1r9a |
G |
T |
6: 5,113,712 (GRCm39) |
E739* |
probably null |
Het |
| Ppp3cc |
G |
T |
14: 70,478,397 (GRCm39) |
N268K |
probably damaging |
Het |
| Prkag3 |
T |
A |
1: 74,779,919 (GRCm39) |
D472V |
probably damaging |
Het |
| Ptch2 |
A |
T |
4: 116,968,046 (GRCm39) |
D846V |
probably damaging |
Het |
| Rhob |
A |
T |
12: 8,549,388 (GRCm39) |
M82K |
probably damaging |
Het |
| Rps6kc1 |
T |
A |
1: 190,531,672 (GRCm39) |
R777W |
possibly damaging |
Het |
| Sap130 |
T |
A |
18: 31,844,380 (GRCm39) |
V850E |
probably damaging |
Het |
| Sema3a |
T |
G |
5: 13,523,407 (GRCm39) |
N125K |
probably damaging |
Het |
| Sema5a |
A |
G |
15: 32,460,431 (GRCm39) |
D64G |
probably damaging |
Het |
| Sgo2b |
T |
A |
8: 64,384,507 (GRCm39) |
D163V |
possibly damaging |
Het |
| Slc15a1 |
A |
T |
14: 121,728,651 (GRCm39) |
Y31* |
probably null |
Het |
| Smchd1 |
A |
T |
17: 71,685,252 (GRCm39) |
M1392K |
probably benign |
Het |
| Sobp |
T |
A |
10: 43,036,827 (GRCm39) |
N37I |
probably damaging |
Het |
| Spock3 |
G |
T |
8: 63,673,739 (GRCm39) |
C142F |
probably damaging |
Het |
| Stx6 |
A |
C |
1: 155,053,650 (GRCm39) |
S86R |
probably benign |
Het |
| Sult2a4 |
C |
A |
7: 13,643,726 (GRCm39) |
M280I |
probably benign |
Het |
| Synm |
A |
T |
7: 67,386,080 (GRCm39) |
D527E |
probably damaging |
Het |
| Tax1bp1 |
C |
T |
6: 52,710,305 (GRCm39) |
R195W |
probably damaging |
Het |
| Themis2 |
A |
T |
4: 132,519,796 (GRCm39) |
N76K |
possibly damaging |
Het |
| Tmem8b |
A |
G |
4: 43,690,234 (GRCm39) |
T890A |
probably benign |
Het |
| Traf7 |
T |
A |
17: 24,730,785 (GRCm39) |
H366L |
possibly damaging |
Het |
| Trim30c |
A |
T |
7: 104,032,459 (GRCm39) |
V289D |
probably benign |
Het |
| Tsr1 |
T |
A |
11: 74,792,914 (GRCm39) |
D407E |
probably damaging |
Het |
| Ubap2 |
G |
T |
4: 41,235,593 (GRCm39) |
A33E |
probably damaging |
Het |
| Unc13d |
C |
A |
11: 115,964,701 (GRCm39) |
R255L |
possibly damaging |
Het |
| Ush2a |
G |
T |
1: 188,542,534 (GRCm39) |
G3367* |
probably null |
Het |
| Vmn1r229 |
T |
C |
17: 21,034,791 (GRCm39) |
L12P |
probably damaging |
Het |
| Vmn2r27 |
C |
A |
6: 124,177,474 (GRCm39) |
G510V |
probably damaging |
Het |
| Vps4b |
T |
C |
1: 106,707,712 (GRCm39) |
E257G |
probably damaging |
Het |
| Vps72 |
T |
C |
3: 95,026,462 (GRCm39) |
S136P |
probably damaging |
Het |
| Wdr36 |
T |
C |
18: 32,976,938 (GRCm39) |
I181T |
possibly damaging |
Het |
| Wfikkn1 |
C |
T |
17: 26,096,765 (GRCm39) |
A520T |
probably benign |
Het |
|
| Other mutations in Cep295 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Cep295
|
APN |
9 |
15,237,368 (GRCm39) |
splice site |
probably null |
|
|
IGL00769:Cep295
|
APN |
9 |
15,237,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00771:Cep295
|
APN |
9 |
15,233,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00850:Cep295
|
APN |
9 |
15,234,148 (GRCm39) |
missense |
probably benign |
0.36 |
|
IGL01505:Cep295
|
APN |
9 |
15,229,345 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01510:Cep295
|
APN |
9 |
15,265,922 (GRCm39) |
nonsense |
probably null |
|
|
IGL01759:Cep295
|
APN |
9 |
15,234,855 (GRCm39) |
splice site |
probably null |
|
|
IGL02415:Cep295
|
APN |
9 |
15,264,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02447:Cep295
|
APN |
9 |
15,243,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02502:Cep295
|
APN |
9 |
15,262,209 (GRCm39) |
splice site |
probably benign |
|
|
IGL02665:Cep295
|
APN |
9 |
15,237,928 (GRCm39) |
splice site |
probably benign |
|
|
IGL02718:Cep295
|
APN |
9 |
15,237,049 (GRCm39) |
splice site |
probably null |
|
|
IGL02995:Cep295
|
APN |
9 |
15,244,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03024:Cep295
|
APN |
9 |
15,236,868 (GRCm39) |
missense |
probably benign |
|
|
R0196:Cep295
|
UTSW |
9 |
15,249,509 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0398:Cep295
|
UTSW |
9 |
15,266,032 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0595:Cep295
|
UTSW |
9 |
15,243,487 (GRCm39) |
nonsense |
probably null |
|
|
R0610:Cep295
|
UTSW |
9 |
15,234,050 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0616:Cep295
|
UTSW |
9 |
15,243,618 (GRCm39) |
nonsense |
probably null |
|
|
R0840:Cep295
|
UTSW |
9 |
15,245,611 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1215:Cep295
|
UTSW |
9 |
15,239,178 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1376:Cep295
|
UTSW |
9 |
15,252,164 (GRCm39) |
splice site |
probably benign |
|
|
R1381:Cep295
|
UTSW |
9 |
15,233,861 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1557:Cep295
|
UTSW |
9 |
15,243,306 (GRCm39) |
nonsense |
probably null |
|
|
R1655:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1682:Cep295
|
UTSW |
9 |
15,245,217 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1700:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1734:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1736:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1743:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1765:Cep295
|
UTSW |
9 |
15,239,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Cep295
|
UTSW |
9 |
15,243,399 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1895:Cep295
|
UTSW |
9 |
15,243,399 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1994:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1995:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2071:Cep295
|
UTSW |
9 |
15,252,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2161:Cep295
|
UTSW |
9 |
15,264,354 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2195:Cep295
|
UTSW |
9 |
15,243,617 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2354:Cep295
|
UTSW |
9 |
15,246,080 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2427:Cep295
|
UTSW |
9 |
15,245,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2992:Cep295
|
UTSW |
9 |
15,244,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3873:Cep295
|
UTSW |
9 |
15,244,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3981:Cep295
|
UTSW |
9 |
15,228,363 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4201:Cep295
|
UTSW |
9 |
15,243,834 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4297:Cep295
|
UTSW |
9 |
15,233,950 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4543:Cep295
|
UTSW |
9 |
15,246,549 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4584:Cep295
|
UTSW |
9 |
15,246,095 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R4724:Cep295
|
UTSW |
9 |
15,242,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4878:Cep295
|
UTSW |
9 |
15,246,252 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4884:Cep295
|
UTSW |
9 |
15,263,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4934:Cep295
|
UTSW |
9 |
15,244,456 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4990:Cep295
|
UTSW |
9 |
15,243,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5057:Cep295
|
UTSW |
9 |
15,233,979 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5153:Cep295
|
UTSW |
9 |
15,268,925 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5180:Cep295
|
UTSW |
9 |
15,243,416 (GRCm39) |
missense |
probably benign |
|
|
R5285:Cep295
|
UTSW |
9 |
15,233,887 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5360:Cep295
|
UTSW |
9 |
15,238,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5419:Cep295
|
UTSW |
9 |
15,235,533 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5432:Cep295
|
UTSW |
9 |
15,262,991 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5625:Cep295
|
UTSW |
9 |
15,252,187 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5637:Cep295
|
UTSW |
9 |
15,245,108 (GRCm39) |
splice site |
probably null |
|
|
R5645:Cep295
|
UTSW |
9 |
15,246,404 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5645:Cep295
|
UTSW |
9 |
15,244,090 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5678:Cep295
|
UTSW |
9 |
15,234,154 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5688:Cep295
|
UTSW |
9 |
15,243,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5807:Cep295
|
UTSW |
9 |
15,243,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5824:Cep295
|
UTSW |
9 |
15,236,952 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5837:Cep295
|
UTSW |
9 |
15,258,280 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5915:Cep295
|
UTSW |
9 |
15,252,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Cep295
|
UTSW |
9 |
15,252,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Cep295
|
UTSW |
9 |
15,233,927 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6332:Cep295
|
UTSW |
9 |
15,246,210 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6383:Cep295
|
UTSW |
9 |
15,244,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6737:Cep295
|
UTSW |
9 |
15,243,647 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6929:Cep295
|
UTSW |
9 |
15,244,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7428:Cep295
|
UTSW |
9 |
15,244,794 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7697:Cep295
|
UTSW |
9 |
15,266,006 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7963:Cep295
|
UTSW |
9 |
15,244,737 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8055:Cep295
|
UTSW |
9 |
15,244,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8069:Cep295
|
UTSW |
9 |
15,233,882 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8092:Cep295
|
UTSW |
9 |
15,244,278 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8117:Cep295
|
UTSW |
9 |
15,245,660 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8140:Cep295
|
UTSW |
9 |
15,252,829 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8178:Cep295
|
UTSW |
9 |
15,244,836 (GRCm39) |
missense |
|
|
|
R8323:Cep295
|
UTSW |
9 |
15,264,357 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8323:Cep295
|
UTSW |
9 |
15,249,529 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8339:Cep295
|
UTSW |
9 |
15,236,846 (GRCm39) |
missense |
|
|
|
R8351:Cep295
|
UTSW |
9 |
15,234,202 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8367:Cep295
|
UTSW |
9 |
15,245,826 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8725:Cep295
|
UTSW |
9 |
15,243,715 (GRCm39) |
nonsense |
probably null |
|
|
R8919:Cep295
|
UTSW |
9 |
15,238,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9015:Cep295
|
UTSW |
9 |
15,244,264 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9054:Cep295
|
UTSW |
9 |
15,235,551 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9088:Cep295
|
UTSW |
9 |
15,233,815 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9159:Cep295
|
UTSW |
9 |
15,252,904 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9243:Cep295
|
UTSW |
9 |
15,243,605 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9408:Cep295
|
UTSW |
9 |
15,244,619 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9424:Cep295
|
UTSW |
9 |
15,244,499 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9455:Cep295
|
UTSW |
9 |
15,245,046 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9607:Cep295
|
UTSW |
9 |
15,234,009 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9648:Cep295
|
UTSW |
9 |
15,234,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9659:Cep295
|
UTSW |
9 |
15,233,846 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9731:Cep295
|
UTSW |
9 |
15,245,262 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
X0065:Cep295
|
UTSW |
9 |
15,234,187 (GRCm39) |
missense |
probably benign |
0.36 |
|
Z1176:Cep295
|
UTSW |
9 |
15,268,993 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Cep295
|
UTSW |
9 |
15,242,113 (GRCm39) |
missense |
|
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAAGCAGCTTTTCCCGAGCCTC -3'
(R):5'- GAACGTCAGTGGCAGTTCTCTCAG -3'
Sequencing Primer
(F):5'- GTCACCCTGCTGAGCTGTAATAG -3'
(R):5'- GCAGTTCTCTCAGGTGGAAAC -3'
|
| Posted On |
2014-03-28 |
Incidental Mutation