Incidental Mutation 'R1891:Pcdh7'
| ID |
211474 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdh7
|
| Ensembl Gene |
ENSMUSG00000029108 |
| Gene Name |
protocadherin 7 |
| Synonyms |
BH-protocadherin |
| MMRRC Submission |
039911-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.119)
|
| Stock # |
R1891 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
57875309-58290572 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 57878217 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 591
(I591F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066306
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068110]
[ENSMUST00000094783]
[ENSMUST00000191837]
[ENSMUST00000199310]
|
| AlphaFold |
A0A0A6YY83 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000068110
AA Change: I591F
PolyPhen 2
Score 0.984 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000066306
Gene: ENSMUSG00000029108
AA Change: I591F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000094783
AA Change: I591F
|
| SMART Domains |
Protein: ENSMUSP00000092376
Gene: ENSMUSG00000029108
AA Change: I591F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000180708
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000191837
AA Change: I591F
PolyPhen 2
Score 0.902 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000142319
Gene: ENSMUSG00000029108
AA Change: I591F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192048
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000192287
AA Change: I251F
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000193156
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200266
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195156
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199310
|
| SMART Domains |
Protein: ENSMUSP00000143387
Gene: ENSMUSG00000029108
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Protocadherin
|
1 |
79 |
5.1e-40 |
PFAM |
|
low complexity region
|
112 |
123 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.4%
- 20x: 92.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca7 |
T |
C |
10: 79,840,874 (GRCm39) |
I921T |
possibly damaging |
Het |
| Abca8a |
T |
C |
11: 109,982,433 (GRCm39) |
K3R |
probably benign |
Het |
| Adgrl3 |
A |
T |
5: 81,659,891 (GRCm39) |
D152V |
probably damaging |
Het |
| Akap6 |
A |
T |
12: 53,188,958 (GRCm39) |
D2124V |
possibly damaging |
Het |
| Akt1 |
A |
G |
12: 112,626,009 (GRCm39) |
F88L |
probably damaging |
Het |
| Ankrd24 |
T |
C |
10: 81,479,342 (GRCm39) |
|
probably benign |
Het |
| Arid4b |
T |
A |
13: 14,310,821 (GRCm39) |
N141K |
possibly damaging |
Het |
| Cacna1c |
C |
A |
6: 118,753,480 (GRCm39) |
D219Y |
probably damaging |
Het |
| Ccdc113 |
A |
G |
8: 96,267,544 (GRCm39) |
K170E |
probably damaging |
Het |
| Ceacam9 |
A |
G |
7: 16,457,880 (GRCm39) |
E136G |
probably damaging |
Het |
| Cfap43 |
A |
G |
19: 47,802,380 (GRCm39) |
L333P |
probably damaging |
Het |
| Chl1 |
A |
G |
6: 103,691,544 (GRCm39) |
D1062G |
possibly damaging |
Het |
| Cimip4 |
T |
A |
15: 78,262,952 (GRCm39) |
D234V |
probably damaging |
Het |
| Ckb |
TCCACCACCA |
TCCACCA |
12: 111,636,079 (GRCm39) |
|
probably benign |
Het |
| Clpp |
T |
A |
17: 57,298,307 (GRCm39) |
V91E |
probably damaging |
Het |
| Cndp1 |
A |
T |
18: 84,637,758 (GRCm39) |
H325Q |
probably null |
Het |
| Cngb3 |
A |
G |
4: 19,366,446 (GRCm39) |
N169S |
probably benign |
Het |
| Cog6 |
A |
C |
3: 52,890,601 (GRCm39) |
I613R |
probably benign |
Het |
| Creb3l1 |
A |
G |
2: 91,817,385 (GRCm39) |
L376P |
probably damaging |
Het |
| Cry2 |
A |
T |
2: 92,243,985 (GRCm39) |
V396D |
possibly damaging |
Het |
| Cxxc5 |
A |
G |
18: 35,992,318 (GRCm39) |
M240V |
possibly damaging |
Het |
| Defa28 |
G |
A |
8: 22,073,801 (GRCm39) |
C68Y |
probably damaging |
Het |
| Ecd |
A |
G |
14: 20,388,227 (GRCm39) |
I187T |
probably damaging |
Het |
| Erg28 |
A |
G |
12: 85,862,962 (GRCm39) |
S117P |
probably benign |
Het |
| Ergic2 |
A |
T |
6: 148,084,577 (GRCm39) |
C319S |
probably damaging |
Het |
| Ess2 |
C |
T |
16: 17,725,644 (GRCm39) |
W183* |
probably null |
Het |
| Evc2 |
A |
C |
5: 37,549,423 (GRCm39) |
D773A |
probably damaging |
Het |
| Fam151b |
T |
A |
13: 92,586,678 (GRCm39) |
T252S |
probably benign |
Het |
| Fbxo28 |
A |
T |
1: 182,145,389 (GRCm39) |
M233K |
probably benign |
Het |
| Fbxw26 |
T |
G |
9: 109,551,232 (GRCm39) |
D355A |
probably benign |
Het |
| Gm4884 |
G |
C |
7: 40,692,539 (GRCm39) |
E169D |
possibly damaging |
Het |
| Hk2 |
C |
T |
6: 82,726,264 (GRCm39) |
R94Q |
probably benign |
Het |
| Hps4 |
G |
A |
5: 112,517,422 (GRCm39) |
|
probably null |
Het |
| Hspg2 |
T |
A |
4: 137,292,801 (GRCm39) |
D4126E |
probably damaging |
Het |
| Kif13a |
T |
C |
13: 47,082,695 (GRCm39) |
E48G |
possibly damaging |
Het |
| Krt31 |
T |
A |
11: 99,938,634 (GRCm39) |
N320Y |
probably damaging |
Het |
| Lca5 |
T |
C |
9: 83,277,661 (GRCm39) |
Y561C |
probably damaging |
Het |
| Lrrk1 |
G |
A |
7: 65,929,048 (GRCm39) |
L1195F |
probably damaging |
Het |
| Ly6g6d |
A |
C |
17: 35,293,269 (GRCm39) |
Y25* |
probably null |
Het |
| Map3k13 |
T |
G |
16: 21,729,836 (GRCm39) |
M489R |
probably damaging |
Het |
| Mcm6 |
C |
T |
1: 128,263,547 (GRCm39) |
R658H |
probably damaging |
Het |
| Mecp2 |
C |
T |
X: 73,080,781 (GRCm39) |
A79T |
probably damaging |
Het |
| Mitf |
A |
G |
6: 97,918,237 (GRCm39) |
T94A |
probably benign |
Het |
| Mpo |
T |
A |
11: 87,692,106 (GRCm39) |
L513* |
probably null |
Het |
| Mst1r |
T |
A |
9: 107,790,661 (GRCm39) |
N722K |
probably damaging |
Het |
| Mthfd1l |
T |
A |
10: 3,982,284 (GRCm39) |
L497* |
probably null |
Het |
| Mtus1 |
C |
T |
8: 41,537,362 (GRCm39) |
S118N |
probably damaging |
Het |
| Mybbp1a |
C |
T |
11: 72,336,863 (GRCm39) |
T565I |
probably benign |
Het |
| Naip2 |
C |
T |
13: 100,291,395 (GRCm39) |
R1181K |
probably benign |
Het |
| Nbas |
T |
C |
12: 13,440,973 (GRCm39) |
M1101T |
possibly damaging |
Het |
| Odad3 |
G |
T |
9: 21,906,677 (GRCm39) |
|
probably null |
Het |
| Or2y1b |
T |
C |
11: 49,208,684 (GRCm39) |
F104L |
probably benign |
Het |
| Or4f60 |
A |
T |
2: 111,902,739 (GRCm39) |
L63Q |
probably damaging |
Het |
| Or52l1 |
A |
T |
7: 104,829,754 (GRCm39) |
Y270* |
probably null |
Het |
| Or5ae1 |
T |
A |
7: 84,565,461 (GRCm39) |
V158D |
possibly damaging |
Het |
| Or6c33 |
T |
C |
10: 129,853,439 (GRCm39) |
S70P |
probably damaging |
Het |
| Or7a40 |
T |
A |
16: 16,491,441 (GRCm39) |
I135F |
probably damaging |
Het |
| Or7g20 |
T |
C |
9: 18,947,274 (GRCm39) |
L285S |
probably damaging |
Het |
| Or8b12b |
T |
A |
9: 37,684,163 (GRCm39) |
D69E |
possibly damaging |
Het |
| Oxct2b |
A |
G |
4: 123,010,938 (GRCm39) |
D286G |
probably benign |
Het |
| Pax5 |
A |
T |
4: 44,691,859 (GRCm39) |
V129E |
probably damaging |
Het |
| Pax7 |
G |
A |
4: 139,511,937 (GRCm39) |
R215C |
probably damaging |
Het |
| Pcdhb22 |
T |
C |
18: 37,652,357 (GRCm39) |
V275A |
probably damaging |
Het |
| Pkp3 |
C |
T |
7: 140,663,969 (GRCm39) |
|
probably null |
Het |
| Plekhb1 |
A |
G |
7: 100,304,599 (GRCm39) |
L35P |
probably damaging |
Het |
| Pole |
T |
A |
5: 110,480,408 (GRCm39) |
F1993Y |
probably damaging |
Het |
| Pramel28 |
A |
T |
4: 143,693,235 (GRCm39) |
V81E |
probably damaging |
Het |
| Prdx1 |
T |
C |
4: 116,556,451 (GRCm39) |
*200R |
probably null |
Het |
| Prkdc |
C |
A |
16: 15,543,300 (GRCm39) |
T1777N |
probably benign |
Het |
| Prss59 |
A |
T |
6: 40,902,967 (GRCm39) |
M135K |
possibly damaging |
Het |
| Ptpn14 |
G |
A |
1: 189,530,850 (GRCm39) |
V106M |
probably damaging |
Het |
| Ptpn23 |
T |
C |
9: 110,222,868 (GRCm39) |
E63G |
possibly damaging |
Het |
| Qser1 |
A |
C |
2: 104,620,444 (GRCm39) |
S123A |
probably benign |
Het |
| Rbm11 |
A |
G |
16: 75,397,675 (GRCm39) |
N202D |
possibly damaging |
Het |
| Robo3 |
T |
A |
9: 37,339,351 (GRCm39) |
Y212F |
probably damaging |
Het |
| Sde2 |
G |
A |
1: 180,687,573 (GRCm39) |
S153N |
probably benign |
Het |
| Serpinb1c |
T |
A |
13: 33,068,235 (GRCm39) |
D179V |
probably benign |
Het |
| Skint6 |
T |
C |
4: 112,703,893 (GRCm39) |
D994G |
possibly damaging |
Het |
| Sorbs1 |
A |
G |
19: 40,381,904 (GRCm39) |
S46P |
probably damaging |
Het |
| St8sia4 |
T |
C |
1: 95,519,433 (GRCm39) |
T352A |
possibly damaging |
Het |
| Stab1 |
C |
A |
14: 30,863,287 (GRCm39) |
R2133L |
probably benign |
Het |
| Stk11ip |
T |
C |
1: 75,509,060 (GRCm39) |
C730R |
probably benign |
Het |
| Tedc2 |
C |
A |
17: 24,435,292 (GRCm39) |
E366* |
probably null |
Het |
| Tedc2 |
T |
A |
17: 24,435,291 (GRCm39) |
E366V |
probably damaging |
Het |
| Tle4 |
A |
T |
19: 14,522,150 (GRCm39) |
|
probably null |
Het |
| Tmem200a |
T |
A |
10: 25,869,970 (GRCm39) |
N100Y |
probably damaging |
Het |
| Tnnt2 |
A |
T |
1: 135,768,597 (GRCm39) |
|
probably null |
Het |
| Ttn |
T |
A |
2: 76,706,302 (GRCm39) |
|
probably benign |
Het |
| Ubac1 |
A |
G |
2: 25,904,974 (GRCm39) |
V88A |
probably benign |
Het |
| Urgcp |
T |
C |
11: 5,666,910 (GRCm39) |
E476G |
probably benign |
Het |
| Vmn1r201 |
G |
A |
13: 22,659,425 (GRCm39) |
R213H |
probably benign |
Het |
| Vmn2r84 |
C |
T |
10: 130,221,938 (GRCm39) |
V761M |
possibly damaging |
Het |
| Vwde |
A |
T |
6: 13,187,454 (GRCm39) |
Y678N |
probably damaging |
Het |
| Wnk2 |
C |
A |
13: 49,206,200 (GRCm39) |
E1865* |
probably null |
Het |
| Zc3h3 |
A |
C |
15: 75,628,780 (GRCm39) |
M838R |
possibly damaging |
Het |
| Zfp959 |
T |
A |
17: 56,204,604 (GRCm39) |
C211S |
probably damaging |
Het |
|
| Other mutations in Pcdh7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Pcdh7
|
APN |
5 |
57,878,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00920:Pcdh7
|
APN |
5 |
57,877,473 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00990:Pcdh7
|
APN |
5 |
57,877,806 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01367:Pcdh7
|
APN |
5 |
58,286,566 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL01388:Pcdh7
|
APN |
5 |
57,877,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01543:Pcdh7
|
APN |
5 |
57,878,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01750:Pcdh7
|
APN |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02010:Pcdh7
|
APN |
5 |
58,286,597 (GRCm39) |
missense |
probably benign |
|
|
IGL02014:Pcdh7
|
APN |
5 |
57,877,045 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02269:Pcdh7
|
APN |
5 |
58,070,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03051:Pcdh7
|
APN |
5 |
58,286,415 (GRCm39) |
missense |
probably damaging |
0.99 |
|
floated
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
proposed
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P0037:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0003:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0421:Pcdh7
|
UTSW |
5 |
57,877,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0551:Pcdh7
|
UTSW |
5 |
57,879,336 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Pcdh7
|
UTSW |
5 |
57,877,405 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0732:Pcdh7
|
UTSW |
5 |
57,878,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0755:Pcdh7
|
UTSW |
5 |
57,877,664 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1080:Pcdh7
|
UTSW |
5 |
57,876,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1381:Pcdh7
|
UTSW |
5 |
57,878,882 (GRCm39) |
nonsense |
probably null |
|
|
R1591:Pcdh7
|
UTSW |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2011:Pcdh7
|
UTSW |
5 |
57,876,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Pcdh7
|
UTSW |
5 |
58,286,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2147:Pcdh7
|
UTSW |
5 |
58,286,458 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R2848:Pcdh7
|
UTSW |
5 |
57,877,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Pcdh7
|
UTSW |
5 |
58,286,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4075:Pcdh7
|
UTSW |
5 |
57,879,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4231:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4236:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4352:Pcdh7
|
UTSW |
5 |
57,879,361 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4420:Pcdh7
|
UTSW |
5 |
58,286,512 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4449:Pcdh7
|
UTSW |
5 |
57,877,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4584:Pcdh7
|
UTSW |
5 |
57,878,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4686:Pcdh7
|
UTSW |
5 |
58,286,511 (GRCm39) |
missense |
probably benign |
|
|
R4837:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4838:Pcdh7
|
UTSW |
5 |
57,878,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4947:Pcdh7
|
UTSW |
5 |
57,879,258 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5053:Pcdh7
|
UTSW |
5 |
57,878,943 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5068:Pcdh7
|
UTSW |
5 |
57,879,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5117:Pcdh7
|
UTSW |
5 |
57,879,090 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5132:Pcdh7
|
UTSW |
5 |
57,885,463 (GRCm39) |
missense |
probably benign |
|
|
R5248:Pcdh7
|
UTSW |
5 |
58,286,515 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5294:Pcdh7
|
UTSW |
5 |
57,885,453 (GRCm39) |
splice site |
probably null |
|
|
R5420:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5777:Pcdh7
|
UTSW |
5 |
57,876,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5800:Pcdh7
|
UTSW |
5 |
57,879,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5834:Pcdh7
|
UTSW |
5 |
57,878,970 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5870:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5917:Pcdh7
|
UTSW |
5 |
57,879,097 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6014:Pcdh7
|
UTSW |
5 |
57,878,497 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6193:Pcdh7
|
UTSW |
5 |
57,877,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6240:Pcdh7
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Pcdh7
|
UTSW |
5 |
58,099,607 (GRCm39) |
splice site |
probably null |
|
|
R6418:Pcdh7
|
UTSW |
5 |
57,879,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6907:Pcdh7
|
UTSW |
5 |
57,876,471 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7058:Pcdh7
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7069:Pcdh7
|
UTSW |
5 |
57,877,126 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7073:Pcdh7
|
UTSW |
5 |
57,878,299 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7463:Pcdh7
|
UTSW |
5 |
57,878,340 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7509:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7588:Pcdh7
|
UTSW |
5 |
57,877,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7707:Pcdh7
|
UTSW |
5 |
57,877,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7734:Pcdh7
|
UTSW |
5 |
57,876,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7899:Pcdh7
|
UTSW |
5 |
57,877,152 (GRCm39) |
missense |
probably benign |
|
|
R8194:Pcdh7
|
UTSW |
5 |
57,877,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8480:Pcdh7
|
UTSW |
5 |
58,286,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8890:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Pcdh7
|
UTSW |
5 |
57,879,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8990:Pcdh7
|
UTSW |
5 |
57,879,364 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9264:Pcdh7
|
UTSW |
5 |
58,286,663 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9272:Pcdh7
|
UTSW |
5 |
57,878,779 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9294:Pcdh7
|
UTSW |
5 |
57,878,677 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9518:Pcdh7
|
UTSW |
5 |
58,070,513 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9597:Pcdh7
|
UTSW |
5 |
57,877,197 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9642:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9745:Pcdh7
|
UTSW |
5 |
57,879,622 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0021:Pcdh7
|
UTSW |
5 |
57,878,826 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
X0026:Pcdh7
|
UTSW |
5 |
57,876,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Pcdh7
|
UTSW |
5 |
57,877,006 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGACAACCCTCCTGTCTTTGG -3'
(R):5'- CATCCATCACGGTGACCATC -3'
Sequencing Primer
(F):5'- CCTGTCTTTGGCCAGTCTGTG -3'
(R):5'- CGGTGACCATCCCCACAG -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation