Mutagenetix > Incidental Mutation

Incidental Mutation 'R0143:Zfp462'

22430

Institutional Source

Beutler Lab

Gene Symbol

Zfp462

Ensembl Gene

ENSMUSG00000060206

Gene Name

zinc finger protein 462

Synonyms

9430078C22Rik, Zfpip, Gt4-2

MMRRC Submission

038428-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.881) question?

Stock #

R0143 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

54945048-55083563 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

C to A at 55023402 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000095677 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000030131] [ENSMUST00000079605] [ENSMUST00000098070]

AlphaFold

B1AWL2

Predicted Effect

probably benign
Transcript: ENSMUST00000030131

SMART Domains

Protein: ENSMUSP00000030131
Gene: ENSMUSG00000060206

Domain	Start	End	E-Value	Type
ZnF_C2H2	35	58	4.81e0	SMART
ZnF_C2H2	106	129	6.67e-2	SMART
ZnF_C2H2	153	176	3.47e0	SMART
ZnF_C2H2	210	233	7.29e0	SMART
ZnF_C2H2	311	334	2.17e-1	SMART
ZnF_C2H2	356	379	6.57e0	SMART
ZnF_C2H2	418	441	5.34e-1	SMART
low complexity region	450	463	N/A	INTRINSIC
ZnF_C2H2	501	524	8.22e-2	SMART
ZnF_C2H2	538	561	5.34e0	SMART
ZnF_C2H2	608	631	6.4e0	SMART
low complexity region	655	676	N/A	INTRINSIC
ZnF_C2H2	687	711	3.05e1	SMART
ZnF_C2H2	733	755	1.08e-1	SMART
low complexity region	757	771	N/A	INTRINSIC
ZnF_C2H2	809	831	1.51e0	SMART
ZnF_C2H2	892	914	3.11e-2	SMART
ZnF_C2H2	926	948	4.11e-2	SMART
ZnF_C2H2	955	978	4.98e-1	SMART
ZnF_C2H2	984	1007	5.5e-3	SMART
ZnF_C2H2	1092	1115	7.05e-1	SMART
ZnF_C2H2	1121	1144	5.48e0	SMART
ZnF_C2H2	1155	1177	6.13e-1	SMART
ZnF_C2H2	1201	1223	1.26e-2	SMART
ZnF_C2H2	1229	1252	2.02e-1	SMART
low complexity region	1273	1296	N/A	INTRINSIC
ZnF_C2H2	1315	1337	2.2e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000079605

SMART Domains

Protein: ENSMUSP00000078555
Gene: ENSMUSG00000060206

Domain	Start	End	E-Value	Type
ZnF_C2H2	35	58	4.81e0	SMART
ZnF_C2H2	106	129	6.67e-2	SMART
ZnF_C2H2	153	176	3.47e0	SMART
ZnF_C2H2	210	233	7.29e0	SMART
ZnF_C2H2	311	334	2.17e-1	SMART
ZnF_C2H2	356	379	6.57e0	SMART
ZnF_C2H2	418	441	5.34e-1	SMART
low complexity region	450	463	N/A	INTRINSIC
ZnF_C2H2	501	524	8.22e-2	SMART
ZnF_C2H2	538	561	5.34e0	SMART
ZnF_C2H2	608	631	6.4e0	SMART
low complexity region	655	676	N/A	INTRINSIC
ZnF_C2H2	687	711	3.05e1	SMART
ZnF_C2H2	733	755	1.08e-1	SMART
low complexity region	757	771	N/A	INTRINSIC
ZnF_C2H2	809	831	1.51e0	SMART
ZnF_C2H2	893	915	3.11e-2	SMART
ZnF_C2H2	927	949	4.11e-2	SMART
ZnF_C2H2	956	979	4.98e-1	SMART
ZnF_C2H2	985	1008	5.5e-3	SMART
ZnF_C2H2	1093	1116	7.05e-1	SMART
ZnF_C2H2	1122	1145	5.48e0	SMART
ZnF_C2H2	1156	1178	6.13e-1	SMART
ZnF_C2H2	1202	1224	1.26e-2	SMART
ZnF_C2H2	1230	1253	2.02e-1	SMART
low complexity region	1274	1297	N/A	INTRINSIC
ZnF_C2H2	1316	1338	2.2e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000098070

SMART Domains

Protein: ENSMUSP00000095677
Gene: ENSMUSG00000060206

Domain	Start	End	E-Value	Type
ZnF_C2H2	4	27	5.81e-2	SMART
low complexity region	81	94	N/A	INTRINSIC
ZnF_C2H2	108	131	1.79e-2	SMART
ZnF_C2H2	162	185	4.65e-1	SMART
low complexity region	194	215	N/A	INTRINSIC
ZnF_C2H2	243	266	4.98e-1	SMART
low complexity region	332	343	N/A	INTRINSIC
ZnF_C2H2	440	463	1.01e-1	SMART
ZnF_C2H2	471	493	2.86e-1	SMART
low complexity region	503	515	N/A	INTRINSIC
low complexity region	536	592	N/A	INTRINSIC
ZnF_C2H2	593	616	2.53e-2	SMART
low complexity region	707	736	N/A	INTRINSIC
ZnF_C2H2	835	858	5.62e0	SMART
ZnF_C2H2	878	900	2.14e0	SMART
ZnF_C2H2	917	940	6.67e-2	SMART
ZnF_C2H2	1023	1046	5.72e-1	SMART
low complexity region	1092	1100	N/A	INTRINSIC
ZnF_C2H2	1107	1130	4.23e0	SMART
ZnF_C2H2	1183	1206	4.81e0	SMART
ZnF_C2H2	1254	1277	6.67e-2	SMART
ZnF_C2H2	1301	1324	3.47e0	SMART
ZnF_C2H2	1358	1381	7.29e0	SMART
ZnF_C2H2	1459	1482	2.17e-1	SMART
ZnF_C2H2	1504	1527	6.57e0	SMART
ZnF_C2H2	1566	1589	5.34e-1	SMART
low complexity region	1598	1611	N/A	INTRINSIC
ZnF_C2H2	1649	1672	8.22e-2	SMART
ZnF_C2H2	1686	1709	5.34e0	SMART
ZnF_C2H2	1756	1779	6.4e0	SMART
low complexity region	1803	1824	N/A	INTRINSIC
ZnF_C2H2	1835	1859	3.05e1	SMART
ZnF_C2H2	1881	1903	1.08e-1	SMART
low complexity region	1905	1919	N/A	INTRINSIC
ZnF_C2H2	1957	1979	1.51e0	SMART
ZnF_C2H2	2014	2036	4.11e-2	SMART
ZnF_C2H2	2043	2066	4.98e-1	SMART
ZnF_C2H2	2072	2095	5.5e-3	SMART
ZnF_C2H2	2180	2203	7.05e-1	SMART
ZnF_C2H2	2209	2232	5.48e0	SMART
ZnF_C2H2	2243	2265	6.13e-1	SMART
ZnF_C2H2	2289	2311	1.26e-2	SMART
ZnF_C2H2	2317	2340	2.02e-1	SMART
low complexity region	2361	2384	N/A	INTRINSIC
ZnF_C2H2	2403	2425	2.2e-2	SMART

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.6%
20x: 93.6%

Validation Efficiency

97% (76/78)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to C2H2-type zinc finger family of proteins. It contains multiple C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]

Allele List at MGI

Other mutations in this stock

Total: 68 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ablim3	A	T	18: 61,988,288 (GRCm39)	I145N	probably benign	Het
Ankrd1	G	A	19: 36,096,713 (GRCm39)	A38V	probably benign	Het
Ankrd34b	A	G	13: 92,576,268 (GRCm39)	E500G	probably damaging	Het
Arhgef12	T	C	9: 42,916,890 (GRCm39)	T419A	probably damaging	Het
B3galt2	A	T	1: 143,523,072 (GRCm39)	N403Y	possibly damaging	Het
Bbx	C	T	16: 50,100,755 (GRCm39)	E47K	probably benign	Het
C4b	G	A	17: 34,953,193 (GRCm39)		probably benign	Het
Cacna1e	A	T	1: 154,324,693 (GRCm39)		probably null	Het
Cdh3	T	C	8: 107,237,857 (GRCm39)	V17A	probably benign	Het
Cog7	A	T	7: 121,550,387 (GRCm39)	L379Q	probably damaging	Het
Cul9	T	C	17: 46,837,336 (GRCm39)	N1044S	possibly damaging	Het
Cyp4b1	C	T	4: 115,493,071 (GRCm39)	D258N	probably damaging	Het
Ddx39a	T	C	8: 84,447,179 (GRCm39)	V113A	probably benign	Het
Dennd4b	A	T	3: 90,179,671 (GRCm39)	H643L	probably damaging	Het
Dpy19l3	T	C	7: 35,413,640 (GRCm39)	T334A	probably benign	Het
Dsg3	T	C	18: 20,669,882 (GRCm39)	L632S	probably damaging	Het
Dtx4	G	A	19: 12,463,846 (GRCm39)	T312I	probably damaging	Het
Dusp18	C	T	11: 3,847,243 (GRCm39)	R78C	probably benign	Het
Fes	A	C	7: 80,033,643 (GRCm39)	F203V	probably benign	Het
Fhad1	C	A	4: 141,656,957 (GRCm39)		probably benign	Het
Gjb2	T	C	14: 57,337,526 (GRCm39)		silent	Het
Gm5828	T	C	1: 16,838,579 (GRCm39)		noncoding transcript	Het
Gsdma	A	C	11: 98,557,080 (GRCm39)	E65A	probably damaging	Het
Hck	T	A	2: 152,976,140 (GRCm39)		probably null	Het
Henmt1	A	T	3: 108,861,118 (GRCm39)	H47L	probably damaging	Het
Hivep2	T	C	10: 14,005,099 (GRCm39)	F566L	probably damaging	Het
Hnrnpl	T	C	7: 28,513,617 (GRCm39)		probably benign	Het
Igsf3	T	C	3: 101,342,917 (GRCm39)	I518T	probably damaging	Het
Ireb2	T	C	9: 54,793,193 (GRCm39)	F223L	probably benign	Het
Isoc2a	T	C	7: 4,894,331 (GRCm39)		probably null	Het
Krt73	T	A	15: 101,709,208 (GRCm39)	R200W	probably damaging	Het
Lgals9	T	A	11: 78,854,361 (GRCm39)	I308F	probably damaging	Het
Lrp1	A	G	10: 127,429,811 (GRCm39)	F420L	probably damaging	Het
Mep1b	T	C	18: 21,228,164 (GRCm39)		probably benign	Het
Mex3a	G	T	3: 88,443,562 (GRCm39)	A213S	probably benign	Het
Mmp13	T	C	9: 7,276,558 (GRCm39)	F218L	probably damaging	Het
Ncf1	G	T	5: 134,255,991 (GRCm39)		probably benign	Het
Notch2	A	G	3: 98,053,433 (GRCm39)	D2032G	probably damaging	Het
Or10h28	T	C	17: 33,488,471 (GRCm39)	S258P	probably damaging	Het
Or5p1	A	G	7: 107,916,202 (GRCm39)	I34V	probably benign	Het
Or9i1b	A	C	19: 13,896,614 (GRCm39)	I77L	probably damaging	Het
Pex16	G	A	2: 92,210,802 (GRCm39)	G312D	probably damaging	Het
Pex5	A	T	6: 124,375,448 (GRCm39)	W525R	probably damaging	Het
Plcb4	T	A	2: 135,818,131 (GRCm39)	I799N	probably damaging	Het
Poldip3	G	A	15: 83,012,144 (GRCm39)	L372F	probably damaging	Het
Polg2	C	A	11: 106,668,352 (GRCm39)	V174L	probably benign	Het
Prrt4	C	G	6: 29,170,670 (GRCm39)	G594A	probably damaging	Het
Prss1	A	G	6: 41,440,522 (GRCm39)	D199G	probably damaging	Het
Rbms2	T	A	10: 127,973,823 (GRCm39)	Q207L	probably benign	Het
Retreg2	A	G	1: 75,123,074 (GRCm39)	D334G	possibly damaging	Het
Slc6a15	T	G	10: 103,253,929 (GRCm39)	C622G	probably benign	Het
Spdya	T	A	17: 71,865,635 (GRCm39)	D84E	probably damaging	Het
Stat3	A	T	11: 100,785,982 (GRCm39)	S432T	possibly damaging	Het
Tiam1	A	T	16: 89,695,088 (GRCm39)	V123E	probably benign	Het
Tnpo3	A	G	6: 29,565,651 (GRCm39)		probably benign	Het
Tnrc6c	A	C	11: 117,643,811 (GRCm39)	N1481H	probably damaging	Het
Top3b	T	C	16: 16,701,389 (GRCm39)	S234P	probably damaging	Het
Tor1aip2	A	T	1: 155,935,294 (GRCm39)	T10S	probably benign	Het
Tpsab1	T	A	17: 25,562,418 (GRCm39)	H303L	probably benign	Het
Traf3	T	A	12: 111,228,010 (GRCm39)	V407D	probably damaging	Het
Trim33	T	A	3: 103,259,417 (GRCm39)	D1035E	probably benign	Het
Ttc38	T	C	15: 85,737,920 (GRCm39)	V402A	possibly damaging	Het
Ube4b	C	T	4: 149,439,914 (GRCm39)	R646H	possibly damaging	Het
Usp8	C	A	2: 126,597,009 (GRCm39)		probably benign	Het
Zdbf2	A	T	1: 63,347,233 (GRCm39)	I1871F	probably benign	Het
Zfp345	T	A	2: 150,314,475 (GRCm39)	Q354L	probably benign	Het
Zfp81	G	A	17: 33,554,095 (GRCm39)	H240Y	possibly damaging	Het
Zfp830	A	G	11: 82,655,994 (GRCm39)	D266G	possibly damaging	Het

Other mutations in Zfp462

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00162:Zfp462	APN	4	55,011,483 (GRCm39)	splice site	probably null
IGL00421:Zfp462	APN	4	55,023,576 (GRCm39)	missense	probably benign	0.00
IGL00899:Zfp462	APN	4	55,007,732 (GRCm39)	missense	probably damaging	1.00
IGL01549:Zfp462	APN	4	55,013,181 (GRCm39)	missense	probably damaging	1.00
IGL01627:Zfp462	APN	4	55,008,912 (GRCm39)	missense	possibly damaging	0.93
IGL01715:Zfp462	APN	4	55,008,586 (GRCm39)	missense	probably benign	0.20
IGL01862:Zfp462	APN	4	55,023,441 (GRCm39)	missense	probably damaging	1.00
IGL01878:Zfp462	APN	4	55,010,613 (GRCm39)	missense	probably damaging	1.00
IGL01913:Zfp462	APN	4	55,012,138 (GRCm39)	missense	probably benign	0.04
IGL02029:Zfp462	APN	4	55,079,395 (GRCm39)	splice site	probably benign
IGL02338:Zfp462	APN	4	55,010,292 (GRCm39)	missense	possibly damaging	0.88
IGL02552:Zfp462	APN	4	55,010,613 (GRCm39)	missense	probably damaging	1.00
IGL02623:Zfp462	APN	4	55,012,986 (GRCm39)	missense	probably damaging	1.00
IGL02750:Zfp462	APN	4	55,060,236 (GRCm39)	missense	probably null	1.00
IGL02815:Zfp462	APN	4	55,051,303 (GRCm39)	missense	probably damaging	1.00
IGL03204:Zfp462	APN	4	55,080,785 (GRCm39)	missense	possibly damaging	0.80
FR4304:Zfp462	UTSW	4	55,009,758 (GRCm39)	unclassified	probably benign
FR4304:Zfp462	UTSW	4	55,009,757 (GRCm39)	unclassified	probably benign
FR4737:Zfp462	UTSW	4	55,009,760 (GRCm39)	unclassified	probably benign
FR4737:Zfp462	UTSW	4	55,009,758 (GRCm39)	unclassified	probably benign
FR4976:Zfp462	UTSW	4	55,009,761 (GRCm39)	unclassified	probably benign
FR4976:Zfp462	UTSW	4	55,009,760 (GRCm39)	unclassified	probably benign
P0035:Zfp462	UTSW	4	55,009,086 (GRCm39)	missense	probably benign
R0052:Zfp462	UTSW	4	55,011,762 (GRCm39)	missense	probably benign	0.03
R0145:Zfp462	UTSW	4	55,010,529 (GRCm39)	missense	probably damaging	1.00
R0315:Zfp462	UTSW	4	55,079,314 (GRCm39)	missense	probably damaging	0.99
R0349:Zfp462	UTSW	4	55,008,768 (GRCm39)	missense	probably benign
R0359:Zfp462	UTSW	4	55,013,689 (GRCm39)	missense	probably damaging	1.00
R0413:Zfp462	UTSW	4	55,010,534 (GRCm39)	missense	probably damaging	0.99
R0554:Zfp462	UTSW	4	55,013,689 (GRCm39)	missense	probably damaging	1.00
R0616:Zfp462	UTSW	4	55,011,951 (GRCm39)	missense	probably damaging	1.00
R0631:Zfp462	UTSW	4	55,007,563 (GRCm39)	start codon destroyed	possibly damaging	0.60
R1086:Zfp462	UTSW	4	55,013,000 (GRCm39)	missense	probably damaging	1.00
R1499:Zfp462	UTSW	4	55,060,046 (GRCm39)	missense	probably damaging	1.00
R1509:Zfp462	UTSW	4	55,007,667 (GRCm39)	missense	probably damaging	1.00
R1526:Zfp462	UTSW	4	55,009,002 (GRCm39)	missense	probably benign
R1541:Zfp462	UTSW	4	55,008,928 (GRCm39)	missense	possibly damaging	0.53
R1691:Zfp462	UTSW	4	55,013,489 (GRCm39)	missense	possibly damaging	0.70
R1843:Zfp462	UTSW	4	55,010,010 (GRCm39)	missense	possibly damaging	0.88
R2086:Zfp462	UTSW	4	55,010,830 (GRCm39)	missense	probably damaging	1.00
R2109:Zfp462	UTSW	4	55,008,496 (GRCm39)	missense	probably benign	0.00
R2148:Zfp462	UTSW	4	55,013,670 (GRCm39)	missense	probably benign	0.01
R2179:Zfp462	UTSW	4	55,009,524 (GRCm39)	missense	possibly damaging	0.73
R2325:Zfp462	UTSW	4	55,013,712 (GRCm39)	missense	probably benign
R2352:Zfp462	UTSW	4	55,008,313 (GRCm39)	missense	probably null
R2566:Zfp462	UTSW	4	55,008,522 (GRCm39)	missense	probably benign	0.00
R3879:Zfp462	UTSW	4	55,060,095 (GRCm39)	missense	probably damaging	1.00
R3969:Zfp462	UTSW	4	55,012,402 (GRCm39)	missense	probably damaging	1.00
R4273:Zfp462	UTSW	4	55,008,411 (GRCm39)	missense	probably benign	0.00
R4413:Zfp462	UTSW	4	55,012,672 (GRCm39)	missense	probably damaging	0.99
R4510:Zfp462	UTSW	4	55,008,934 (GRCm39)	missense	possibly damaging	0.86
R4511:Zfp462	UTSW	4	55,008,934 (GRCm39)	missense	possibly damaging	0.86
R4609:Zfp462	UTSW	4	55,011,889 (GRCm39)	missense	probably damaging	1.00
R4632:Zfp462	UTSW	4	55,012,981 (GRCm39)	missense	probably damaging	1.00
R4649:Zfp462	UTSW	4	55,009,349 (GRCm39)	missense	probably benign
R4682:Zfp462	UTSW	4	55,011,376 (GRCm39)	missense	probably damaging	1.00
R4696:Zfp462	UTSW	4	55,008,612 (GRCm39)	missense	probably benign
R4744:Zfp462	UTSW	4	55,011,598 (GRCm39)	missense	probably damaging	1.00
R4747:Zfp462	UTSW	4	55,013,476 (GRCm39)	missense	probably benign	0.00
R4819:Zfp462	UTSW	4	55,060,044 (GRCm39)	missense	probably damaging	1.00
R4827:Zfp462	UTSW	4	55,012,213 (GRCm39)	missense	probably damaging	1.00
R4854:Zfp462	UTSW	4	55,010,668 (GRCm39)	missense	probably damaging	1.00
R4879:Zfp462	UTSW	4	55,009,444 (GRCm39)	missense	probably benign	0.02
R4891:Zfp462	UTSW	4	55,060,055 (GRCm39)	missense	probably damaging	1.00
R4993:Zfp462	UTSW	4	55,051,204 (GRCm39)	missense	possibly damaging	0.62
R5118:Zfp462	UTSW	4	55,010,667 (GRCm39)	missense	probably damaging	1.00
R5171:Zfp462	UTSW	4	55,016,986 (GRCm39)	splice site	probably null
R5173:Zfp462	UTSW	4	55,011,115 (GRCm39)	missense	probably damaging	0.99
R5221:Zfp462	UTSW	4	55,016,887 (GRCm39)	missense	possibly damaging	0.86
R5268:Zfp462	UTSW	4	55,012,299 (GRCm39)	missense	probably benign
R5314:Zfp462	UTSW	4	55,013,178 (GRCm39)	missense	probably damaging	1.00
R5429:Zfp462	UTSW	4	55,060,077 (GRCm39)	missense	probably damaging	1.00
R5518:Zfp462	UTSW	4	55,009,818 (GRCm39)	missense	probably damaging	0.99
R5525:Zfp462	UTSW	4	55,050,281 (GRCm39)	missense	possibly damaging	0.73
R5620:Zfp462	UTSW	4	55,013,464 (GRCm39)	missense	probably benign	0.01
R5775:Zfp462	UTSW	4	55,010,590 (GRCm39)	missense	probably damaging	0.99
R6126:Zfp462	UTSW	4	55,023,573 (GRCm39)	missense	probably benign	0.01
R6280:Zfp462	UTSW	4	55,010,253 (GRCm39)	missense	probably benign	0.00
R6325:Zfp462	UTSW	4	55,080,680 (GRCm39)	missense	probably benign	0.04
R6542:Zfp462	UTSW	4	55,023,433 (GRCm39)	missense	probably damaging	1.00
R6612:Zfp462	UTSW	4	55,012,324 (GRCm39)	splice site	probably null
R6663:Zfp462	UTSW	4	55,008,933 (GRCm39)	missense	possibly damaging	0.53
R6872:Zfp462	UTSW	4	55,012,326 (GRCm39)	missense	probably benign	0.01
R6889:Zfp462	UTSW	4	55,007,671 (GRCm39)	missense	probably damaging	1.00
R6896:Zfp462	UTSW	4	55,009,544 (GRCm39)	missense	possibly damaging	0.72
R6913:Zfp462	UTSW	4	55,007,775 (GRCm39)	missense	probably benign	0.25
R6988:Zfp462	UTSW	4	55,080,716 (GRCm39)	missense	probably benign	0.00
R7131:Zfp462	UTSW	4	55,009,380 (GRCm39)	missense	probably benign
R7151:Zfp462	UTSW	4	55,051,271 (GRCm39)	missense	probably damaging	0.99
R7684:Zfp462	UTSW	4	55,008,908 (GRCm39)	missense	probably benign
R7741:Zfp462	UTSW	4	55,008,637 (GRCm39)	missense	probably benign	0.00
R7750:Zfp462	UTSW	4	55,016,958 (GRCm39)	missense	probably benign	0.06
R7812:Zfp462	UTSW	4	55,008,509 (GRCm39)	missense	probably benign	0.00
R7863:Zfp462	UTSW	4	55,007,747 (GRCm39)	missense	probably benign
R7898:Zfp462	UTSW	4	55,012,995 (GRCm39)	missense	probably damaging	0.98
R7993:Zfp462	UTSW	4	55,011,907 (GRCm39)	missense	probably damaging	1.00
R7995:Zfp462	UTSW	4	55,011,907 (GRCm39)	missense	probably damaging	1.00
R8023:Zfp462	UTSW	4	55,073,106 (GRCm39)	critical splice donor site	probably null
R8394:Zfp462	UTSW	4	55,011,862 (GRCm39)	missense	probably damaging	1.00
R8669:Zfp462	UTSW	4	55,051,313 (GRCm39)	missense	probably damaging	0.99
R8877:Zfp462	UTSW	4	55,011,097 (GRCm39)	missense	probably damaging	0.98
R8980:Zfp462	UTSW	4	55,009,681 (GRCm39)	unclassified	probably benign
R9023:Zfp462	UTSW	4	55,007,563 (GRCm39)	start codon destroyed	probably null	0.00
R9243:Zfp462	UTSW	4	55,009,595 (GRCm39)	nonsense	probably null
R9378:Zfp462	UTSW	4	55,011,510 (GRCm39)	missense	probably benign	0.00
R9417:Zfp462	UTSW	4	55,016,988 (GRCm39)	missense	probably benign	0.26
R9476:Zfp462	UTSW	4	55,080,735 (GRCm39)	missense	probably benign
R9510:Zfp462	UTSW	4	55,080,735 (GRCm39)	missense	probably benign
R9610:Zfp462	UTSW	4	55,009,545 (GRCm39)	missense	possibly damaging	0.73
R9628:Zfp462	UTSW	4	55,009,423 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- TGTGGACTGAAAGAAATCTGCCCTG -3'
(R):5'- GCAGAATACGCACTCCTTCCTACTC -3'

Sequencing Primer
(F):5'- CATGATTGTCAGTGACCAGC -3'
(R):5'- ctcagcccaacactccc -3'

Posted On

2013-04-16