Incidental Mutation 'R2143:Naip6'
| ID |
236543 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Naip6
|
| Ensembl Gene |
ENSMUSG00000078942 |
| Gene Name |
NLR family, apoptosis inhibitory protein 6 |
| Synonyms |
Naip-rs4, Birc1f, Naip-rs4A |
| MMRRC Submission |
040146-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.142)
|
| Stock # |
R2143 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
100417629-100453124 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 100436367 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Asparagine
at position 719
(D719N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112867
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042220]
[ENSMUST00000118574]
|
| AlphaFold |
Q9JIB6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000042220
AA Change: D719N
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000041766
Gene: ENSMUSG00000078942
AA Change: D719N
| Domain | Start | End | E-Value | Type |
|---|
|
BIR
|
58 |
129 |
6.21e-20 |
SMART |
|
BIR
|
157 |
229 |
8.04e-37 |
SMART |
|
BIR
|
276 |
347 |
5.19e-31 |
SMART |
|
Pfam:NACHT
|
464 |
618 |
7.6e-37 |
PFAM |
|
low complexity region
|
851 |
862 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000118574
AA Change: D719N
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000112867
Gene: ENSMUSG00000078942
AA Change: D719N
| Domain | Start | End | E-Value | Type |
|---|
|
BIR
|
58 |
129 |
6.21e-20 |
SMART |
|
BIR
|
157 |
229 |
8.04e-37 |
SMART |
|
BIR
|
276 |
347 |
5.19e-31 |
SMART |
|
Pfam:NACHT
|
464 |
618 |
2.5e-35 |
PFAM |
|
low complexity region
|
851 |
862 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: Closest sequence match is AF381772. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 111 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310034C09Rik |
G |
C |
16: 88,556,053 (GRCm39) |
S89T |
probably benign |
Het |
| 4930522L14Rik |
C |
G |
5: 109,884,616 (GRCm39) |
C414S |
probably damaging |
Het |
| 4930553M12Rik |
G |
A |
4: 88,786,411 (GRCm39) |
T69I |
unknown |
Het |
| 4930553M12Rik |
T |
A |
4: 88,786,412 (GRCm39) |
T69S |
unknown |
Het |
| Apobr |
G |
A |
7: 126,186,288 (GRCm39) |
E600K |
probably benign |
Het |
| Armc8 |
C |
A |
9: 99,387,361 (GRCm39) |
R419L |
probably damaging |
Het |
| Ash1l |
T |
A |
3: 88,892,726 (GRCm39) |
M1535K |
probably benign |
Het |
| Atf7ip2 |
A |
G |
16: 10,058,509 (GRCm39) |
E316G |
probably null |
Het |
| Atp2a1 |
G |
A |
7: 126,047,897 (GRCm39) |
R638* |
probably null |
Het |
| Atp8b4 |
A |
T |
2: 126,216,430 (GRCm39) |
I672N |
probably damaging |
Het |
| Atrn |
T |
C |
2: 130,799,916 (GRCm39) |
V431A |
probably benign |
Het |
| Babam1 |
T |
C |
8: 71,851,084 (GRCm39) |
S116P |
probably damaging |
Het |
| Ccdc142 |
T |
C |
6: 83,079,203 (GRCm39) |
L180P |
probably damaging |
Het |
| Cd52 |
T |
C |
4: 133,821,048 (GRCm39) |
|
probably benign |
Het |
| Cdk17 |
T |
C |
10: 93,053,881 (GRCm39) |
L125P |
probably damaging |
Het |
| Ckap5 |
A |
G |
2: 91,396,090 (GRCm39) |
D531G |
probably benign |
Het |
| Cntn5 |
G |
T |
9: 9,748,420 (GRCm39) |
P487Q |
probably damaging |
Het |
| Crispld1 |
C |
T |
1: 17,819,860 (GRCm39) |
T286I |
probably benign |
Het |
| Crtap |
T |
C |
9: 114,209,036 (GRCm39) |
Y336C |
probably damaging |
Het |
| Ctu2 |
T |
A |
8: 123,205,891 (GRCm39) |
I213K |
probably benign |
Het |
| Dmac2l |
A |
G |
12: 69,787,828 (GRCm39) |
Q88R |
probably damaging |
Het |
| Dsc3 |
A |
G |
18: 20,113,743 (GRCm39) |
F393S |
possibly damaging |
Het |
| Dsg2 |
T |
A |
18: 20,712,218 (GRCm39) |
I118N |
probably damaging |
Het |
| Dstyk |
T |
A |
1: 132,391,113 (GRCm39) |
M838K |
probably damaging |
Het |
| Elmo3 |
T |
C |
8: 106,035,305 (GRCm39) |
V450A |
probably damaging |
Het |
| Eml5 |
A |
C |
12: 98,776,864 (GRCm39) |
F1417C |
probably damaging |
Het |
| Enam |
T |
A |
5: 88,640,779 (GRCm39) |
M147K |
probably benign |
Het |
| Entpd1 |
T |
C |
19: 40,725,227 (GRCm39) |
Y409H |
probably damaging |
Het |
| Extl1 |
C |
A |
4: 134,098,355 (GRCm39) |
E225D |
probably benign |
Het |
| Fbn2 |
A |
G |
18: 58,186,065 (GRCm39) |
V1761A |
possibly damaging |
Het |
| Fsip2 |
A |
T |
2: 82,820,615 (GRCm39) |
L5449F |
possibly damaging |
Het |
| Gabra5 |
G |
A |
7: 57,138,763 (GRCm39) |
T95I |
probably damaging |
Het |
| Gal3st2c |
C |
T |
1: 93,937,173 (GRCm39) |
Q373* |
probably null |
Het |
| Gbp5 |
A |
C |
3: 142,209,593 (GRCm39) |
T180P |
probably damaging |
Het |
| Glb1 |
T |
C |
9: 114,266,892 (GRCm39) |
L212P |
probably damaging |
Het |
| Gm11596 |
A |
T |
11: 99,683,789 (GRCm39) |
C110* |
probably null |
Het |
| Gpat2 |
T |
C |
2: 127,275,682 (GRCm39) |
F487L |
probably damaging |
Het |
| Hsph1 |
A |
T |
5: 149,554,951 (GRCm39) |
H110Q |
probably damaging |
Het |
| Ikbke |
C |
A |
1: 131,201,211 (GRCm39) |
V176L |
probably damaging |
Het |
| Ildr2 |
T |
C |
1: 166,096,895 (GRCm39) |
V38A |
probably damaging |
Het |
| Inpp4a |
G |
T |
1: 37,426,827 (GRCm39) |
C326F |
probably damaging |
Het |
| Irak2 |
T |
A |
6: 113,649,788 (GRCm39) |
V141D |
probably benign |
Het |
| Jade1 |
G |
A |
3: 41,559,143 (GRCm39) |
R408Q |
probably benign |
Het |
| Jmjd7 |
C |
A |
2: 119,860,601 (GRCm39) |
|
probably null |
Het |
| Kdm7a |
C |
T |
6: 39,145,884 (GRCm39) |
V348I |
possibly damaging |
Het |
| Kif20a |
A |
G |
18: 34,758,657 (GRCm39) |
D42G |
possibly damaging |
Het |
| Klhl7 |
A |
T |
5: 24,305,861 (GRCm39) |
M37L |
probably benign |
Het |
| Krt5 |
A |
G |
15: 101,620,794 (GRCm39) |
I151T |
probably damaging |
Het |
| Krtap1-5 |
T |
C |
11: 99,471,644 (GRCm39) |
I50V |
probably benign |
Het |
| Letm1 |
A |
AG |
5: 33,926,859 (GRCm39) |
|
probably null |
Het |
| Lrrc71 |
C |
T |
3: 87,652,828 (GRCm39) |
W148* |
probably null |
Het |
| Lsmem1 |
GTACATACATACATACATACATACATACA |
GTACATACATACATACATACATACATACATACA |
12: 40,235,260 (GRCm39) |
|
probably null |
Het |
| Map1a |
T |
A |
2: 121,132,426 (GRCm39) |
S843T |
probably damaging |
Het |
| Map1s |
T |
A |
8: 71,363,608 (GRCm39) |
D48E |
probably damaging |
Het |
| Mast4 |
A |
G |
13: 102,871,983 (GRCm39) |
F2462L |
possibly damaging |
Het |
| Mettl21e |
T |
A |
1: 44,249,398 (GRCm39) |
Y86F |
probably benign |
Het |
| Myh6 |
A |
T |
14: 55,190,411 (GRCm39) |
D1035E |
probably damaging |
Het |
| Nat8f2 |
T |
G |
6: 85,845,239 (GRCm39) |
H41P |
probably benign |
Het |
| Ncam1 |
T |
A |
9: 49,454,319 (GRCm39) |
Q597L |
possibly damaging |
Het |
| Nek1 |
T |
A |
8: 61,481,730 (GRCm39) |
I215K |
probably damaging |
Het |
| Nol11 |
A |
T |
11: 107,071,881 (GRCm39) |
S237R |
probably benign |
Het |
| Npr2 |
T |
C |
4: 43,648,166 (GRCm39) |
F870S |
probably damaging |
Het |
| Nsd1 |
T |
C |
13: 55,408,210 (GRCm39) |
Y1285H |
probably damaging |
Het |
| Nup93 |
C |
T |
8: 95,023,108 (GRCm39) |
Q229* |
probably null |
Het |
| Or4a15 |
C |
T |
2: 89,193,447 (GRCm39) |
E109K |
probably damaging |
Het |
| Or7g12 |
G |
A |
9: 18,900,099 (GRCm39) |
A272T |
probably benign |
Het |
| Pappa |
T |
A |
4: 65,099,186 (GRCm39) |
Y568* |
probably null |
Het |
| Parva |
A |
G |
7: 112,159,274 (GRCm39) |
D180G |
possibly damaging |
Het |
| Pask |
C |
T |
1: 93,249,019 (GRCm39) |
A794T |
probably benign |
Het |
| Pax1 |
T |
A |
2: 147,207,802 (GRCm39) |
C225S |
probably damaging |
Het |
| Pde4dip |
T |
A |
3: 97,795,835 (GRCm39) |
E51V |
possibly damaging |
Het |
| Pde6c |
A |
T |
19: 38,150,777 (GRCm39) |
H562L |
probably damaging |
Het |
| Pet100 |
T |
G |
8: 3,672,355 (GRCm39) |
L14R |
probably damaging |
Het |
| Pfkfb2 |
T |
C |
1: 130,626,460 (GRCm39) |
T438A |
probably benign |
Het |
| Pira2 |
A |
T |
7: 3,847,344 (GRCm39) |
L115Q |
probably damaging |
Het |
| Polr2d |
T |
A |
18: 31,929,132 (GRCm39) |
L127Q |
probably damaging |
Het |
| Prkd1 |
A |
G |
12: 50,536,694 (GRCm39) |
V130A |
possibly damaging |
Het |
| Psd3 |
T |
C |
8: 68,417,003 (GRCm39) |
D45G |
probably damaging |
Het |
| Ptpn13 |
A |
G |
5: 103,703,999 (GRCm39) |
T1344A |
probably benign |
Het |
| Ptpn6 |
T |
A |
6: 124,701,947 (GRCm39) |
H406L |
probably benign |
Het |
| Ric1 |
A |
T |
19: 29,510,652 (GRCm39) |
S78C |
probably damaging |
Het |
| Ric1 |
G |
A |
19: 29,510,653 (GRCm39) |
S78N |
probably damaging |
Het |
| Scgb1b2 |
G |
T |
7: 30,991,188 (GRCm39) |
|
probably benign |
Het |
| Senp7 |
A |
G |
16: 55,990,169 (GRCm39) |
H639R |
probably benign |
Het |
| Sgtb |
A |
T |
13: 104,260,767 (GRCm39) |
D72V |
probably damaging |
Het |
| Slc44a5 |
T |
C |
3: 153,964,086 (GRCm39) |
M484T |
probably benign |
Het |
| Slc5a1 |
A |
G |
5: 33,318,140 (GRCm39) |
K598E |
probably benign |
Het |
| Slit3 |
T |
A |
11: 35,503,088 (GRCm39) |
|
probably null |
Het |
| Smc1b |
T |
C |
15: 85,008,003 (GRCm39) |
H258R |
probably benign |
Het |
| Smu1 |
T |
C |
4: 40,744,073 (GRCm39) |
D318G |
probably damaging |
Het |
| Sned1 |
T |
A |
1: 93,199,406 (GRCm39) |
F495L |
probably damaging |
Het |
| Svs3a |
C |
A |
2: 164,131,804 (GRCm39) |
S124Y |
probably damaging |
Het |
| Syngr4 |
A |
G |
7: 45,536,464 (GRCm39) |
V186A |
probably benign |
Het |
| Tars3 |
G |
A |
7: 65,305,539 (GRCm39) |
M254I |
possibly damaging |
Het |
| Tdpoz1 |
T |
A |
3: 93,578,143 (GRCm39) |
R214* |
probably null |
Het |
| Tm2d3 |
A |
G |
7: 65,344,987 (GRCm39) |
D54G |
probably damaging |
Het |
| Trim66 |
A |
T |
7: 109,074,320 (GRCm39) |
I647N |
probably damaging |
Het |
| Triml2 |
T |
A |
8: 43,646,548 (GRCm39) |
W346R |
probably damaging |
Het |
| Trp53bp1 |
A |
T |
2: 121,046,545 (GRCm39) |
V1085D |
probably benign |
Het |
| Trpv2 |
T |
C |
11: 62,483,612 (GRCm39) |
V483A |
probably benign |
Het |
| Ugp2 |
G |
T |
11: 21,278,949 (GRCm39) |
N412K |
probably benign |
Het |
| Upf1 |
T |
C |
8: 70,792,004 (GRCm39) |
D418G |
probably null |
Het |
| Vmn2r77 |
C |
A |
7: 86,461,152 (GRCm39) |
P826Q |
probably damaging |
Het |
| Vrtn |
T |
C |
12: 84,696,936 (GRCm39) |
M562T |
probably benign |
Het |
| Wdr55 |
A |
G |
18: 36,895,419 (GRCm39) |
N132S |
possibly damaging |
Het |
| Wipf2 |
A |
T |
11: 98,787,040 (GRCm39) |
R356S |
possibly damaging |
Het |
| Zdhhc6 |
T |
C |
19: 55,287,228 (GRCm39) |
K411E |
probably benign |
Het |
| Zfp260 |
A |
G |
7: 29,804,765 (GRCm39) |
K222E |
probably damaging |
Het |
| Zfp280d |
A |
G |
9: 72,220,011 (GRCm39) |
N237S |
probably damaging |
Het |
| Zfp445 |
T |
G |
9: 122,682,547 (GRCm39) |
S465R |
possibly damaging |
Het |
| Zfp821 |
A |
G |
8: 110,450,979 (GRCm39) |
D324G |
probably damaging |
Het |
|
| Other mutations in Naip6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00677:Naip6
|
APN |
13 |
100,452,525 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01123:Naip6
|
APN |
13 |
100,440,946 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01151:Naip6
|
APN |
13 |
100,435,601 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01382:Naip6
|
APN |
13 |
100,436,364 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01415:Naip6
|
APN |
13 |
100,439,798 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01654:Naip6
|
APN |
13 |
100,435,853 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01662:Naip6
|
APN |
13 |
100,436,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01726:Naip6
|
APN |
13 |
100,439,760 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01810:Naip6
|
APN |
13 |
100,424,603 (GRCm39) |
splice site |
probably benign |
|
|
IGL01867:Naip6
|
APN |
13 |
100,436,820 (GRCm39) |
missense |
probably benign |
0.40 |
|
IGL01926:Naip6
|
APN |
13 |
100,436,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01964:Naip6
|
APN |
13 |
100,435,238 (GRCm39) |
splice site |
probably benign |
|
|
IGL02145:Naip6
|
APN |
13 |
100,433,486 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02160:Naip6
|
APN |
13 |
100,435,933 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02214:Naip6
|
APN |
13 |
100,452,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02342:Naip6
|
APN |
13 |
100,439,748 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02568:Naip6
|
APN |
13 |
100,452,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02573:Naip6
|
APN |
13 |
100,435,979 (GRCm39) |
nonsense |
probably null |
|
|
IGL02680:Naip6
|
APN |
13 |
100,420,256 (GRCm39) |
missense |
probably benign |
|
|
IGL02829:Naip6
|
APN |
13 |
100,437,273 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02833:Naip6
|
APN |
13 |
100,436,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02851:Naip6
|
APN |
13 |
100,437,168 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02860:Naip6
|
APN |
13 |
100,436,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02886:Naip6
|
APN |
13 |
100,436,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03155:Naip6
|
APN |
13 |
100,452,932 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R0032:Naip6
|
UTSW |
13 |
100,439,745 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0310:Naip6
|
UTSW |
13 |
100,444,721 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R0437:Naip6
|
UTSW |
13 |
100,433,432 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R0472:Naip6
|
UTSW |
13 |
100,438,768 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0560:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0638:Naip6
|
UTSW |
13 |
100,437,036 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0792:Naip6
|
UTSW |
13 |
100,420,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0963:Naip6
|
UTSW |
13 |
100,452,983 (GRCm39) |
missense |
probably benign |
0.11 |
|
R1102:Naip6
|
UTSW |
13 |
100,440,923 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1278:Naip6
|
UTSW |
13 |
100,436,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1462:Naip6
|
UTSW |
13 |
100,436,748 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1462:Naip6
|
UTSW |
13 |
100,436,748 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1544:Naip6
|
UTSW |
13 |
100,452,983 (GRCm39) |
missense |
probably benign |
|
|
R1595:Naip6
|
UTSW |
13 |
100,435,602 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1749:Naip6
|
UTSW |
13 |
100,444,763 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1838:Naip6
|
UTSW |
13 |
100,452,644 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1863:Naip6
|
UTSW |
13 |
100,437,067 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1914:Naip6
|
UTSW |
13 |
100,435,936 (GRCm39) |
missense |
probably benign |
0.13 |
|
R2001:Naip6
|
UTSW |
13 |
100,437,237 (GRCm39) |
missense |
probably benign |
0.44 |
|
R2082:Naip6
|
UTSW |
13 |
100,440,852 (GRCm39) |
splice site |
probably null |
|
|
R2174:Naip6
|
UTSW |
13 |
100,435,495 (GRCm39) |
missense |
probably benign |
|
|
R2266:Naip6
|
UTSW |
13 |
100,420,067 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R2284:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2285:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2286:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2351:Naip6
|
UTSW |
13 |
100,420,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2363:Naip6
|
UTSW |
13 |
100,452,928 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R2445:Naip6
|
UTSW |
13 |
100,437,176 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2971:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2975:Naip6
|
UTSW |
13 |
100,424,695 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3081:Naip6
|
UTSW |
13 |
100,436,961 (GRCm39) |
missense |
probably benign |
|
|
R3082:Naip6
|
UTSW |
13 |
100,452,925 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3122:Naip6
|
UTSW |
13 |
100,453,031 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3417:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3943:Naip6
|
UTSW |
13 |
100,431,247 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3944:Naip6
|
UTSW |
13 |
100,431,247 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4080:Naip6
|
UTSW |
13 |
100,435,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4166:Naip6
|
UTSW |
13 |
100,452,657 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4396:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4397:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4418:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4512:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4670:Naip6
|
UTSW |
13 |
100,431,239 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4671:Naip6
|
UTSW |
13 |
100,431,239 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4722:Naip6
|
UTSW |
13 |
100,443,580 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4811:Naip6
|
UTSW |
13 |
100,422,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4900:Naip6
|
UTSW |
13 |
100,433,477 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5162:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5316:Naip6
|
UTSW |
13 |
100,420,290 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5403:Naip6
|
UTSW |
13 |
100,436,585 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5437:Naip6
|
UTSW |
13 |
100,439,812 (GRCm39) |
nonsense |
probably null |
|
|
R5507:Naip6
|
UTSW |
13 |
100,435,423 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5631:Naip6
|
UTSW |
13 |
100,436,646 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5657:Naip6
|
UTSW |
13 |
100,436,909 (GRCm39) |
missense |
probably benign |
|
|
R5684:Naip6
|
UTSW |
13 |
100,436,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5786:Naip6
|
UTSW |
13 |
100,436,724 (GRCm39) |
missense |
probably benign |
|
|
R5787:Naip6
|
UTSW |
13 |
100,436,724 (GRCm39) |
missense |
probably benign |
|
|
R5788:Naip6
|
UTSW |
13 |
100,436,724 (GRCm39) |
missense |
probably benign |
|
|
R5878:Naip6
|
UTSW |
13 |
100,436,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5895:Naip6
|
UTSW |
13 |
100,452,500 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5898:Naip6
|
UTSW |
13 |
100,435,829 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6113:Naip6
|
UTSW |
13 |
100,435,794 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6141:Naip6
|
UTSW |
13 |
100,444,741 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6199:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6321:Naip6
|
UTSW |
13 |
100,436,909 (GRCm39) |
missense |
probably benign |
|
|
R6402:Naip6
|
UTSW |
13 |
100,437,226 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6435:Naip6
|
UTSW |
13 |
100,431,249 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6477:Naip6
|
UTSW |
13 |
100,452,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6601:Naip6
|
UTSW |
13 |
100,420,266 (GRCm39) |
missense |
probably benign |
|
|
R6638:Naip6
|
UTSW |
13 |
100,436,909 (GRCm39) |
missense |
probably benign |
|
|
R6639:Naip6
|
UTSW |
13 |
100,436,909 (GRCm39) |
missense |
probably benign |
|
|
R6804:Naip6
|
UTSW |
13 |
100,435,675 (GRCm39) |
missense |
probably benign |
|
|
R6922:Naip6
|
UTSW |
13 |
100,438,706 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6975:Naip6
|
UTSW |
13 |
100,452,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7050:Naip6
|
UTSW |
13 |
100,452,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7135:Naip6
|
UTSW |
13 |
100,436,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7140:Naip6
|
UTSW |
13 |
100,436,708 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7182:Naip6
|
UTSW |
13 |
100,452,657 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7196:Naip6
|
UTSW |
13 |
100,436,666 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7234:Naip6
|
UTSW |
13 |
100,452,011 (GRCm39) |
nonsense |
probably null |
|
|
R7259:Naip6
|
UTSW |
13 |
100,440,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7322:Naip6
|
UTSW |
13 |
100,435,896 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7332:Naip6
|
UTSW |
13 |
100,437,209 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R7339:Naip6
|
UTSW |
13 |
100,452,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7353:Naip6
|
UTSW |
13 |
100,436,259 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7485:Naip6
|
UTSW |
13 |
100,420,359 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7597:Naip6
|
UTSW |
13 |
100,437,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7835:Naip6
|
UTSW |
13 |
100,452,512 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7840:Naip6
|
UTSW |
13 |
100,451,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8082:Naip6
|
UTSW |
13 |
100,436,961 (GRCm39) |
missense |
probably benign |
|
|
R8082:Naip6
|
UTSW |
13 |
100,436,909 (GRCm39) |
missense |
probably benign |
|
|
R8103:Naip6
|
UTSW |
13 |
100,437,851 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8164:Naip6
|
UTSW |
13 |
100,452,797 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8206:Naip6
|
UTSW |
13 |
100,431,344 (GRCm39) |
nonsense |
probably null |
|
|
R8258:Naip6
|
UTSW |
13 |
100,452,920 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8259:Naip6
|
UTSW |
13 |
100,452,920 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8348:Naip6
|
UTSW |
13 |
100,436,894 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R8405:Naip6
|
UTSW |
13 |
100,436,784 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8406:Naip6
|
UTSW |
13 |
100,436,784 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8441:Naip6
|
UTSW |
13 |
100,422,265 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R8448:Naip6
|
UTSW |
13 |
100,436,894 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R8465:Naip6
|
UTSW |
13 |
100,433,423 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8501:Naip6
|
UTSW |
13 |
100,436,784 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8502:Naip6
|
UTSW |
13 |
100,436,784 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8687:Naip6
|
UTSW |
13 |
100,435,636 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8806:Naip6
|
UTSW |
13 |
100,437,161 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9186:Naip6
|
UTSW |
13 |
100,436,390 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9340:Naip6
|
UTSW |
13 |
100,452,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9352:Naip6
|
UTSW |
13 |
100,437,893 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9585:Naip6
|
UTSW |
13 |
100,436,577 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9597:Naip6
|
UTSW |
13 |
100,436,646 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9601:Naip6
|
UTSW |
13 |
100,436,961 (GRCm39) |
missense |
probably benign |
|
|
X0066:Naip6
|
UTSW |
13 |
100,451,970 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Naip6
|
UTSW |
13 |
100,437,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Naip6
|
UTSW |
13 |
100,435,925 (GRCm39) |
missense |
probably benign |
0.20 |
|
Z1177:Naip6
|
UTSW |
13 |
100,452,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TATTGCCTTCAGAGGTGAGTC -3'
(R):5'- ATCAAAATGCATCTGCCCAGG -3'
Sequencing Primer
(F):5'- CCTTCAGAGGTGAGTCAATTTGTCTC -3'
(R):5'- TGCCCAGGATGACTTTCAAG -3'
|
| Posted On |
2014-10-01 |
Incidental Mutation