Incidental Mutation 'IGL02439:Vmn2r66'
ID293400
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r66
Ensembl Gene ENSMUSG00000094950
Gene Namevomeronasal 2, receptor 66
SynonymsF830104D24Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.187) question?
Stock #IGL02439
Quality Score
Status
Chromosome7
Chromosomal Location84994645-85012020 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to T at 85005247 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000122645 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000124773]
Predicted Effect probably benign
Transcript: ENSMUST00000124773
SMART Domains Protein: ENSMUSP00000122645
Gene: ENSMUSG00000094950

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:ANF_receptor 77 463 5e-31 PFAM
Pfam:NCD3G 507 559 6e-21 PFAM
Pfam:7tm_3 589 827 3.8e-52 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2610042L04Rik A T 14: 4,348,890 Y17F probably benign Het
Ablim2 A C 5: 35,857,862 T507P possibly damaging Het
Arhgef28 T C 13: 97,931,139 Y1426C possibly damaging Het
Armc4 T A 18: 7,268,444 R358S probably benign Het
Cftr T A 6: 18,258,238 Y592* probably null Het
Eogt C T 6: 97,143,973 G93D possibly damaging Het
Exosc9 A G 3: 36,553,031 probably benign Het
Frem1 T C 4: 82,956,345 I1329V probably benign Het
Gal3st1 T C 11: 3,998,110 F106L possibly damaging Het
Gulp1 A T 1: 44,781,004 I216F probably damaging Het
Ints13 A T 6: 146,554,223 probably benign Het
Kars G A 8: 111,997,636 T453I probably benign Het
Kif14 A G 1: 136,490,261 D844G probably damaging Het
Lgals3bp A T 11: 118,398,220 C93S probably damaging Het
Lst1 T C 17: 35,186,982 I32V probably benign Het
Malsu1 T A 6: 49,075,187 Y114N probably damaging Het
Ndufa5 A T 6: 24,519,202 V41E probably damaging Het
Nme6 C A 9: 109,841,931 P80T probably damaging Het
Olfr202 A G 16: 59,284,455 L14P probably damaging Het
Padi4 T C 4: 140,746,221 D635G probably damaging Het
Pcf11 C T 7: 92,661,841 S313N possibly damaging Het
Pdik1l T C 4: 134,278,704 H309R probably benign Het
Pdk2 A T 11: 95,039,497 probably benign Het
Pprc1 A G 19: 46,072,319 S1606G possibly damaging Het
Ptch1 A G 13: 63,545,096 I230T probably damaging Het
Scn10a C T 9: 119,618,848 R1381Q probably benign Het
Sestd1 T C 2: 77,196,830 K479E possibly damaging Het
Sez6l2 C T 7: 126,968,189 S892L probably damaging Het
Slc39a9 G T 12: 80,666,576 A83S probably benign Het
Slc6a6 A G 6: 91,749,827 Y483C probably damaging Het
Srrm1 G A 4: 135,325,104 P658L unknown Het
Tas2r131 A G 6: 132,957,769 S26P probably damaging Het
Timd2 A G 11: 46,678,236 probably benign Het
Tmem126a T C 7: 90,455,433 E27G probably damaging Het
Tns2 G A 15: 102,114,543 G1256E probably damaging Het
Trpv6 T A 6: 41,625,487 I322F probably damaging Het
Tshr G A 12: 91,537,547 V420M probably damaging Het
Ttn C A 2: 76,766,087 A20161S probably damaging Het
Zfp438 T A 18: 5,213,216 S581C probably damaging Het
Other mutations in Vmn2r66
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00321:Vmn2r66 APN 7 85007091 missense probably benign
IGL01562:Vmn2r66 APN 7 85007287 missense probably benign 0.03
IGL01689:Vmn2r66 APN 7 85007825 missense probably damaging 1.00
IGL02237:Vmn2r66 APN 7 84994700 missense probably benign
IGL02415:Vmn2r66 APN 7 85006812 missense probably damaging 0.97
IGL02545:Vmn2r66 APN 7 85006590 missense possibly damaging 0.50
IGL02708:Vmn2r66 APN 7 85006588 missense probably benign 0.00
IGL02794:Vmn2r66 APN 7 84995415 missense probably benign 0.00
IGL02885:Vmn2r66 APN 7 84995515 missense probably benign 0.00
IGL02975:Vmn2r66 APN 7 85006974 missense probably damaging 0.98
IGL03027:Vmn2r66 APN 7 84995569 splice site probably benign
IGL03081:Vmn2r66 APN 7 85007930 missense probably benign
PIT4131001:Vmn2r66 UTSW 7 84995093 missense probably damaging 1.00
R0098:Vmn2r66 UTSW 7 85005757 missense probably damaging 1.00
R0504:Vmn2r66 UTSW 7 85006815 missense probably damaging 0.99
R0557:Vmn2r66 UTSW 7 84994764 missense probably damaging 1.00
R0617:Vmn2r66 UTSW 7 84995276 missense probably benign 0.02
R0883:Vmn2r66 UTSW 7 85007862 missense probably benign
R1159:Vmn2r66 UTSW 7 84995405 missense probably benign 0.44
R1168:Vmn2r66 UTSW 7 85006854 missense possibly damaging 0.46
R1172:Vmn2r66 UTSW 7 85005591 missense probably benign 0.04
R1175:Vmn2r66 UTSW 7 85005591 missense probably benign 0.04
R1538:Vmn2r66 UTSW 7 84994958 missense possibly damaging 0.84
R1658:Vmn2r66 UTSW 7 85007747 missense probably benign 0.07
R1937:Vmn2r66 UTSW 7 84995136 missense probably damaging 0.99
R1989:Vmn2r66 UTSW 7 85011993 missense probably benign 0.01
R2698:Vmn2r66 UTSW 7 84995399 missense probably damaging 1.00
R2890:Vmn2r66 UTSW 7 85011819 splice site probably null
R3686:Vmn2r66 UTSW 7 84995189 missense probably damaging 0.96
R4152:Vmn2r66 UTSW 7 85005592 missense probably benign 0.08
R4500:Vmn2r66 UTSW 7 85007954 missense probably damaging 1.00
R4618:Vmn2r66 UTSW 7 84995088 missense possibly damaging 0.62
R4656:Vmn2r66 UTSW 7 85011996 missense possibly damaging 0.87
R4668:Vmn2r66 UTSW 7 84994697 missense probably damaging 1.00
R4942:Vmn2r66 UTSW 7 85007772 missense probably damaging 1.00
R5163:Vmn2r66 UTSW 7 85006809 missense probably benign 0.01
R5223:Vmn2r66 UTSW 7 85007885 missense probably benign
R5377:Vmn2r66 UTSW 7 85006818 missense probably damaging 0.99
R5512:Vmn2r66 UTSW 7 85007941 missense probably damaging 1.00
R5611:Vmn2r66 UTSW 7 85005743 nonsense probably null
R5749:Vmn2r66 UTSW 7 85006771 nonsense probably null
R6131:Vmn2r66 UTSW 7 84995016 missense probably damaging 1.00
R6183:Vmn2r66 UTSW 7 84995558 missense possibly damaging 0.81
R6509:Vmn2r66 UTSW 7 85006846 missense probably benign 0.12
R6930:Vmn2r66 UTSW 7 85012008 missense possibly damaging 0.80
Posted On2015-04-16