Incidental Mutation 'R5590:Abca16'
| ID |
437439 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abca16
|
| Ensembl Gene |
ENSMUSG00000051900 |
| Gene Name |
ATP-binding cassette, sub-family A member 16 |
| Synonyms |
|
| MMRRC Submission |
043143-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5590 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
120008870-120144036 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 120143995 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Methionine
at position 1671
(T1671M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112736
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000056042]
[ENSMUST00000120490]
|
| AlphaFold |
E9PWJ7 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000056042
AA Change: T1670M
PolyPhen 2
Score 0.933 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000061094
Gene: ENSMUSG00000051900
AA Change: T1670M
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
26 |
455 |
2.7e-23 |
PFAM |
|
AAA
|
537 |
720 |
2.01e-7 |
SMART |
|
Pfam:ABC2_membrane_3
|
898 |
1287 |
4.6e-25 |
PFAM |
|
low complexity region
|
1325 |
1336 |
N/A |
INTRINSIC |
|
low complexity region
|
1342 |
1353 |
N/A |
INTRINSIC |
|
AAA
|
1378 |
1563 |
4.23e-6 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000120490
AA Change: T1671M
PolyPhen 2
Score 0.975 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000112736
Gene: ENSMUSG00000051900
AA Change: T1671M
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
25 |
456 |
2.4e-22 |
PFAM |
|
AAA
|
538 |
721 |
2.01e-7 |
SMART |
|
Pfam:ABC2_membrane_3
|
899 |
1288 |
1.1e-27 |
PFAM |
|
low complexity region
|
1326 |
1337 |
N/A |
INTRINSIC |
|
low complexity region
|
1343 |
1354 |
N/A |
INTRINSIC |
|
AAA
|
1379 |
1564 |
4.23e-6 |
SMART |
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.6%
- 20x: 96.2%
|
| Validation Efficiency |
100% (108/108) |
| Allele List at MGI |
All alleles(4) : Targeted(3) Gene trapped(1)
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3100002H09Rik |
T |
G |
4: 124,504,280 (GRCm39) |
M91L |
unknown |
Het |
| A2m |
C |
T |
6: 121,653,891 (GRCm39) |
T1408M |
probably damaging |
Het |
| Adamts8 |
A |
T |
9: 30,862,632 (GRCm39) |
N279I |
probably damaging |
Het |
| Adgre1 |
T |
A |
17: 57,752,034 (GRCm39) |
I594N |
probably damaging |
Het |
| Aldh4a1 |
T |
A |
4: 139,369,415 (GRCm39) |
V322E |
probably damaging |
Het |
| Atp12a |
A |
T |
14: 56,610,837 (GRCm39) |
Y327F |
probably benign |
Het |
| C4b |
T |
C |
17: 34,959,309 (GRCm39) |
T422A |
probably damaging |
Het |
| Cacna1c |
A |
T |
6: 118,664,143 (GRCm39) |
S668T |
probably damaging |
Het |
| Cchcr1 |
A |
T |
17: 35,837,577 (GRCm39) |
E426D |
probably damaging |
Het |
| Ccr3 |
G |
A |
9: 123,828,830 (GRCm39) |
G55D |
probably damaging |
Het |
| Cdipt |
T |
A |
7: 126,578,704 (GRCm39) |
|
probably null |
Het |
| Cep19 |
A |
G |
16: 31,922,716 (GRCm39) |
|
probably benign |
Het |
| Cts6 |
T |
A |
13: 61,349,626 (GRCm39) |
M56L |
probably benign |
Het |
| Cyp3a11 |
C |
A |
5: 145,802,787 (GRCm39) |
M235I |
probably benign |
Het |
| Dnajc21 |
A |
T |
15: 10,462,363 (GRCm39) |
D87E |
possibly damaging |
Het |
| Ell |
A |
C |
8: 70,992,357 (GRCm39) |
M1L |
possibly damaging |
Het |
| Esyt3 |
T |
C |
9: 99,240,466 (GRCm39) |
|
probably benign |
Het |
| Ets1 |
T |
C |
9: 32,640,094 (GRCm39) |
|
probably benign |
Het |
| Fam222b |
T |
A |
11: 78,045,858 (GRCm39) |
M473K |
probably benign |
Het |
| Fanca |
T |
C |
8: 124,030,702 (GRCm39) |
|
probably benign |
Het |
| Fbrsl1 |
G |
T |
5: 110,529,484 (GRCm39) |
A67D |
probably damaging |
Het |
| Fchsd1 |
G |
A |
18: 38,094,380 (GRCm39) |
P622L |
probably damaging |
Het |
| Gal3st2c |
T |
G |
1: 93,936,023 (GRCm39) |
|
probably null |
Het |
| Gins2 |
T |
G |
8: 121,308,486 (GRCm39) |
H166P |
possibly damaging |
Het |
| Gm10118 |
A |
T |
10: 63,762,845 (GRCm39) |
|
probably benign |
Het |
| Gm9979 |
A |
T |
13: 40,859,289 (GRCm39) |
|
noncoding transcript |
Het |
| Hspbap1 |
A |
G |
16: 35,622,033 (GRCm39) |
Y126C |
probably damaging |
Het |
| Hspd1 |
A |
T |
1: 55,123,928 (GRCm39) |
I64N |
probably damaging |
Het |
| Igkv3-4 |
A |
T |
6: 70,649,267 (GRCm39) |
S89C |
probably damaging |
Het |
| Il10ra |
T |
A |
9: 45,176,924 (GRCm39) |
K134* |
probably null |
Het |
| Il12rb1 |
G |
A |
8: 71,266,411 (GRCm39) |
C252Y |
possibly damaging |
Het |
| Il24 |
A |
T |
1: 130,810,253 (GRCm39) |
V201E |
possibly damaging |
Het |
| Inpp1 |
A |
G |
1: 52,833,820 (GRCm39) |
I92T |
probably damaging |
Het |
| Kcnh5 |
T |
C |
12: 75,023,463 (GRCm39) |
D535G |
probably benign |
Het |
| Kcnq4 |
T |
A |
4: 120,573,082 (GRCm39) |
I240F |
probably damaging |
Het |
| Kctd17 |
G |
A |
15: 78,321,502 (GRCm39) |
|
probably benign |
Het |
| Leo1 |
T |
A |
9: 75,364,423 (GRCm39) |
I521N |
possibly damaging |
Het |
| Mdga1 |
A |
G |
17: 30,058,841 (GRCm39) |
L722P |
probably damaging |
Het |
| Met |
G |
T |
6: 17,548,781 (GRCm39) |
V942L |
probably benign |
Het |
| Mfn1 |
A |
T |
3: 32,617,996 (GRCm39) |
T110S |
probably benign |
Het |
| Mrps15 |
T |
C |
4: 125,942,488 (GRCm39) |
I79T |
probably benign |
Het |
| Mycbp2 |
A |
C |
14: 103,360,791 (GRCm39) |
M4497R |
probably damaging |
Het |
| Mylk |
T |
A |
16: 34,699,722 (GRCm39) |
S362T |
probably benign |
Het |
| Mypn |
A |
G |
10: 62,955,827 (GRCm39) |
F1209L |
probably benign |
Het |
| Nab2 |
T |
C |
10: 127,500,526 (GRCm39) |
S189G |
probably damaging |
Het |
| Naxe |
A |
C |
3: 87,963,840 (GRCm39) |
|
probably null |
Het |
| Ncf1 |
A |
G |
5: 134,252,355 (GRCm39) |
V232A |
probably damaging |
Het |
| Nell1 |
A |
G |
7: 49,929,359 (GRCm39) |
Y422C |
probably damaging |
Het |
| Nmnat2 |
G |
T |
1: 152,969,807 (GRCm39) |
G176V |
probably damaging |
Het |
| Npr1 |
A |
G |
3: 90,362,149 (GRCm39) |
S999P |
probably damaging |
Het |
| Nuak1 |
T |
C |
10: 84,211,119 (GRCm39) |
D323G |
probably benign |
Het |
| Or4d10b |
A |
G |
19: 12,036,642 (GRCm39) |
V158A |
probably benign |
Het |
| Or5h23 |
A |
G |
16: 58,906,360 (GRCm39) |
F162S |
probably benign |
Het |
| Or8b3b |
T |
A |
9: 38,584,261 (GRCm39) |
T160S |
probably damaging |
Het |
| Osbpl8 |
T |
C |
10: 111,108,029 (GRCm39) |
S342P |
probably damaging |
Het |
| Pag1 |
A |
T |
3: 9,764,482 (GRCm39) |
Y224N |
probably damaging |
Het |
| Pald1 |
T |
A |
10: 61,179,489 (GRCm39) |
H460L |
probably damaging |
Het |
| Per2 |
G |
A |
1: 91,355,578 (GRCm39) |
Q727* |
probably null |
Het |
| Pex19 |
T |
C |
1: 171,960,779 (GRCm39) |
V134A |
probably benign |
Het |
| Phlpp1 |
A |
T |
1: 106,320,657 (GRCm39) |
I1551F |
possibly damaging |
Het |
| Ppef2 |
A |
T |
5: 92,386,998 (GRCm39) |
V313D |
probably damaging |
Het |
| Prorp |
T |
C |
12: 55,351,257 (GRCm39) |
S189P |
possibly damaging |
Het |
| Pzp |
A |
C |
6: 128,500,759 (GRCm39) |
F153C |
probably damaging |
Het |
| Rasl11a |
A |
G |
5: 146,782,052 (GRCm39) |
H9R |
probably benign |
Het |
| Rfx3 |
A |
T |
19: 27,779,780 (GRCm39) |
|
probably null |
Het |
| Rmnd5b |
A |
T |
11: 51,518,789 (GRCm39) |
I68N |
probably damaging |
Het |
| Senp5 |
T |
A |
16: 31,808,331 (GRCm39) |
S281C |
probably damaging |
Het |
| Sh3rf1 |
G |
A |
8: 61,814,766 (GRCm39) |
E442K |
probably benign |
Het |
| Slc12a3 |
G |
A |
8: 95,072,416 (GRCm39) |
V645M |
probably damaging |
Het |
| Slc22a16 |
T |
C |
10: 40,457,337 (GRCm39) |
F193L |
possibly damaging |
Het |
| Slc35f1 |
A |
T |
10: 52,984,274 (GRCm39) |
T345S |
possibly damaging |
Het |
| Slc9a1 |
G |
A |
4: 133,148,874 (GRCm39) |
R704H |
probably damaging |
Het |
| Spta1 |
A |
T |
1: 174,003,336 (GRCm39) |
Y89F |
possibly damaging |
Het |
| Sspo |
A |
G |
6: 48,451,425 (GRCm39) |
E2741G |
probably damaging |
Het |
| Strn4 |
G |
A |
7: 16,567,799 (GRCm39) |
|
probably null |
Het |
| Tanc2 |
A |
G |
11: 105,814,132 (GRCm39) |
T1859A |
probably damaging |
Het |
| Tbc1d14 |
A |
T |
5: 36,682,389 (GRCm39) |
Y3N |
probably damaging |
Het |
| Tdrd9 |
C |
A |
12: 112,018,414 (GRCm39) |
R1278S |
probably benign |
Het |
| Tenm4 |
C |
A |
7: 96,446,608 (GRCm39) |
A826E |
possibly damaging |
Het |
| Tenm4 |
G |
T |
7: 96,446,607 (GRCm39) |
A826S |
possibly damaging |
Het |
| Tet2 |
C |
T |
3: 133,182,241 (GRCm39) |
|
probably null |
Het |
| Tfec |
A |
G |
6: 16,834,199 (GRCm39) |
L236P |
probably benign |
Het |
| Tjap1 |
A |
G |
17: 46,569,797 (GRCm39) |
S388P |
probably damaging |
Het |
| Tle1 |
T |
C |
4: 72,043,208 (GRCm39) |
T554A |
possibly damaging |
Het |
| Tmem17 |
G |
A |
11: 22,467,450 (GRCm39) |
V83I |
probably benign |
Het |
| Tnrc6b |
C |
T |
15: 80,760,703 (GRCm39) |
H137Y |
probably damaging |
Het |
| Tomm5 |
T |
C |
4: 45,106,679 (GRCm39) |
|
probably benign |
Het |
| Top3b |
T |
A |
16: 16,709,441 (GRCm39) |
|
probably benign |
Het |
| Tph1 |
T |
C |
7: 46,303,216 (GRCm39) |
H254R |
probably damaging |
Het |
| Tpte |
T |
C |
8: 22,841,468 (GRCm39) |
Y487H |
probably damaging |
Het |
| Trappc13 |
T |
A |
13: 104,284,749 (GRCm39) |
D241V |
probably damaging |
Het |
| Trrap |
A |
G |
5: 144,719,075 (GRCm39) |
I193V |
probably benign |
Het |
| Tspear |
A |
T |
10: 77,706,199 (GRCm39) |
H323L |
probably benign |
Het |
| Ttc39a |
A |
T |
4: 109,290,184 (GRCm39) |
|
probably null |
Het |
| Ttn |
A |
T |
2: 76,641,587 (GRCm39) |
L5176Q |
possibly damaging |
Het |
| Tubg1 |
A |
G |
11: 101,014,858 (GRCm39) |
D200G |
probably damaging |
Het |
| Ugdh |
C |
A |
5: 65,580,217 (GRCm39) |
|
probably benign |
Het |
| Uso1 |
A |
G |
5: 92,328,467 (GRCm39) |
N355D |
probably benign |
Het |
| Vamp4 |
T |
C |
1: 162,420,248 (GRCm39) |
|
probably null |
Het |
| Vmn2r5 |
T |
C |
3: 64,411,497 (GRCm39) |
D357G |
probably damaging |
Het |
| Vps52 |
A |
G |
17: 34,180,195 (GRCm39) |
T300A |
probably benign |
Het |
| Wt1 |
A |
T |
2: 104,957,629 (GRCm39) |
H163L |
probably damaging |
Het |
| Xirp2 |
T |
C |
2: 67,344,379 (GRCm39) |
S2207P |
probably benign |
Het |
| Xpo6 |
A |
T |
7: 125,706,250 (GRCm39) |
I30N |
probably damaging |
Het |
| Zfp386 |
T |
A |
12: 116,023,347 (GRCm39) |
I320K |
probably benign |
Het |
|
| Other mutations in Abca16 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00417:Abca16
|
APN |
7 |
120,022,982 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL00590:Abca16
|
APN |
7 |
120,023,038 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01320:Abca16
|
APN |
7 |
120,038,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01322:Abca16
|
APN |
7 |
120,038,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01613:Abca16
|
APN |
7 |
120,140,500 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01774:Abca16
|
APN |
7 |
120,021,024 (GRCm39) |
splice site |
probably benign |
|
|
IGL01774:Abca16
|
APN |
7 |
120,077,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01797:Abca16
|
APN |
7 |
120,113,760 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02406:Abca16
|
APN |
7 |
120,139,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02437:Abca16
|
APN |
7 |
120,132,952 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02541:Abca16
|
APN |
7 |
120,113,881 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02576:Abca16
|
APN |
7 |
120,032,678 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02578:Abca16
|
APN |
7 |
120,023,179 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03156:Abca16
|
APN |
7 |
120,023,074 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL03381:Abca16
|
APN |
7 |
120,127,041 (GRCm39) |
missense |
probably benign |
0.12 |
|
PIT4802001:Abca16
|
UTSW |
7 |
120,139,351 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0024:Abca16
|
UTSW |
7 |
120,032,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0026:Abca16
|
UTSW |
7 |
120,077,146 (GRCm39) |
splice site |
probably benign |
|
|
R0026:Abca16
|
UTSW |
7 |
120,077,146 (GRCm39) |
splice site |
probably benign |
|
|
R0123:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0134:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0225:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0346:Abca16
|
UTSW |
7 |
120,035,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0355:Abca16
|
UTSW |
7 |
120,023,021 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0358:Abca16
|
UTSW |
7 |
120,143,939 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0525:Abca16
|
UTSW |
7 |
120,065,033 (GRCm39) |
nonsense |
probably null |
|
|
R0617:Abca16
|
UTSW |
7 |
120,032,834 (GRCm39) |
splice site |
probably benign |
|
|
R0625:Abca16
|
UTSW |
7 |
120,035,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0835:Abca16
|
UTSW |
7 |
120,065,007 (GRCm39) |
missense |
probably benign |
0.42 |
|
R1445:Abca16
|
UTSW |
7 |
120,119,256 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1535:Abca16
|
UTSW |
7 |
120,139,928 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1567:Abca16
|
UTSW |
7 |
120,030,352 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1694:Abca16
|
UTSW |
7 |
120,119,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1860:Abca16
|
UTSW |
7 |
120,133,986 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1876:Abca16
|
UTSW |
7 |
120,032,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1913:Abca16
|
UTSW |
7 |
120,140,463 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1940:Abca16
|
UTSW |
7 |
120,032,832 (GRCm39) |
splice site |
probably benign |
|
|
R2042:Abca16
|
UTSW |
7 |
120,143,941 (GRCm39) |
missense |
probably benign |
|
|
R2115:Abca16
|
UTSW |
7 |
120,139,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2122:Abca16
|
UTSW |
7 |
120,119,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2265:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2267:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2269:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2993:Abca16
|
UTSW |
7 |
120,134,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3055:Abca16
|
UTSW |
7 |
120,035,074 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3956:Abca16
|
UTSW |
7 |
120,126,975 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4114:Abca16
|
UTSW |
7 |
120,126,290 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4441:Abca16
|
UTSW |
7 |
120,127,024 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4601:Abca16
|
UTSW |
7 |
120,035,920 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4706:Abca16
|
UTSW |
7 |
120,064,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4807:Abca16
|
UTSW |
7 |
120,139,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Abca16
|
UTSW |
7 |
120,074,702 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4937:Abca16
|
UTSW |
7 |
120,126,309 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5152:Abca16
|
UTSW |
7 |
120,139,846 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5257:Abca16
|
UTSW |
7 |
120,035,992 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5258:Abca16
|
UTSW |
7 |
120,035,992 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5330:Abca16
|
UTSW |
7 |
120,102,600 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5388:Abca16
|
UTSW |
7 |
120,139,969 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5810:Abca16
|
UTSW |
7 |
120,035,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6030:Abca16
|
UTSW |
7 |
120,133,021 (GRCm39) |
missense |
probably benign |
|
|
R6030:Abca16
|
UTSW |
7 |
120,133,021 (GRCm39) |
missense |
probably benign |
|
|
R6161:Abca16
|
UTSW |
7 |
120,139,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6313:Abca16
|
UTSW |
7 |
120,126,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6485:Abca16
|
UTSW |
7 |
120,026,390 (GRCm39) |
nonsense |
probably null |
|
|
R6527:Abca16
|
UTSW |
7 |
120,076,995 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6772:Abca16
|
UTSW |
7 |
120,126,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6885:Abca16
|
UTSW |
7 |
120,119,332 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6899:Abca16
|
UTSW |
7 |
120,126,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6941:Abca16
|
UTSW |
7 |
120,140,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6990:Abca16
|
UTSW |
7 |
120,126,950 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7059:Abca16
|
UTSW |
7 |
120,020,971 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7144:Abca16
|
UTSW |
7 |
120,032,796 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7146:Abca16
|
UTSW |
7 |
120,126,974 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7193:Abca16
|
UTSW |
7 |
120,026,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7308:Abca16
|
UTSW |
7 |
120,022,993 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7449:Abca16
|
UTSW |
7 |
120,035,131 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7571:Abca16
|
UTSW |
7 |
120,119,211 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7617:Abca16
|
UTSW |
7 |
120,102,694 (GRCm39) |
nonsense |
probably null |
|
|
R7646:Abca16
|
UTSW |
7 |
120,113,937 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7750:Abca16
|
UTSW |
7 |
120,113,928 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7763:Abca16
|
UTSW |
7 |
120,113,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7840:Abca16
|
UTSW |
7 |
120,074,689 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7946:Abca16
|
UTSW |
7 |
120,126,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8018:Abca16
|
UTSW |
7 |
120,132,866 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8170:Abca16
|
UTSW |
7 |
120,065,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8413:Abca16
|
UTSW |
7 |
120,023,123 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8461:Abca16
|
UTSW |
7 |
120,035,918 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8858:Abca16
|
UTSW |
7 |
120,052,327 (GRCm39) |
missense |
probably benign |
|
|
R8881:Abca16
|
UTSW |
7 |
120,074,794 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9272:Abca16
|
UTSW |
7 |
120,076,993 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9303:Abca16
|
UTSW |
7 |
120,126,989 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9305:Abca16
|
UTSW |
7 |
120,126,989 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9320:Abca16
|
UTSW |
7 |
120,139,320 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9413:Abca16
|
UTSW |
7 |
120,126,422 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9512:Abca16
|
UTSW |
7 |
120,022,963 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9559:Abca16
|
UTSW |
7 |
120,021,019 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9615:Abca16
|
UTSW |
7 |
120,126,404 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9641:Abca16
|
UTSW |
7 |
120,126,308 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R9643:Abca16
|
UTSW |
7 |
120,065,023 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9674:Abca16
|
UTSW |
7 |
120,074,668 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9714:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9799:Abca16
|
UTSW |
7 |
120,132,998 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9800:Abca16
|
UTSW |
7 |
120,119,283 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
RF020:Abca16
|
UTSW |
7 |
120,132,880 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
X0066:Abca16
|
UTSW |
7 |
120,102,609 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAGGGTCACCAAGAGATTCTATG -3'
(R):5'- AAGAGACTTTCGGAGCTGTGC -3'
Sequencing Primer
(F):5'- GTCACCAAGAGATTCTATGTGATAAC -3'
(R):5'- GAGCAAAGTGAATCTTCATAGTTCTG -3'
|
| Posted On |
2016-10-26 |
Incidental Mutation