Incidental Mutation 'R5668:Ly75'
| ID |
442410 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ly75
|
| Ensembl Gene |
ENSMUSG00000026980 |
| Gene Name |
lymphocyte antigen 75 |
| Synonyms |
DEC-205, CD205 |
| MMRRC Submission |
043311-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5668 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
60122447-60213617 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 60184844 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 437
(S437P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000108152
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028362]
[ENSMUST00000112533]
|
| AlphaFold |
Q60767 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000028362
AA Change: S437P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000028362
Gene: ENSMUSG00000026980
AA Change: S437P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112533
AA Change: S437P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108152
Gene: ENSMUSG00000026980
AA Change: S437P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124654
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151984
|
| Meta Mutation Damage Score |
0.8831 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.5%
- 20x: 95.8%
|
| Validation Efficiency |
99% (84/85) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele display abnormalities in CD8-positive T cell morphology and cytotoxic T cell physiology. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(7) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(5)
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actn4 |
A |
G |
7: 28,603,975 (GRCm39) |
W429R |
probably damaging |
Het |
| Afg1l |
C |
T |
10: 42,236,236 (GRCm39) |
C272Y |
probably damaging |
Het |
| Agrn |
T |
C |
4: 156,251,770 (GRCm39) |
T1831A |
probably damaging |
Het |
| Aifm2 |
T |
C |
10: 61,561,696 (GRCm39) |
V14A |
probably damaging |
Het |
| Angptl3 |
A |
T |
4: 98,920,321 (GRCm39) |
|
probably null |
Het |
| Arfgap1 |
A |
T |
2: 180,615,912 (GRCm39) |
D197V |
possibly damaging |
Het |
| Atp1a3 |
T |
C |
7: 24,678,294 (GRCm39) |
|
probably benign |
Het |
| Brwd1 |
T |
C |
16: 95,817,350 (GRCm39) |
I1387M |
probably damaging |
Het |
| Cavin4 |
A |
G |
4: 48,672,499 (GRCm39) |
T315A |
probably benign |
Het |
| Cep128 |
T |
C |
12: 90,966,410 (GRCm39) |
T1066A |
probably benign |
Het |
| Cln3 |
T |
C |
7: 126,171,558 (GRCm39) |
T376A |
probably benign |
Het |
| Cntn4 |
A |
T |
6: 106,656,397 (GRCm39) |
|
silent |
Het |
| Colec12 |
T |
A |
18: 9,848,963 (GRCm39) |
D380E |
probably damaging |
Het |
| Csmd3 |
T |
C |
15: 47,559,151 (GRCm39) |
I2371V |
possibly damaging |
Het |
| Cspg4b |
A |
G |
13: 113,453,701 (GRCm39) |
S55G |
possibly damaging |
Het |
| Cxcl3 |
T |
C |
5: 90,935,299 (GRCm39) |
S99P |
unknown |
Het |
| Ddx60 |
A |
G |
8: 62,453,612 (GRCm39) |
R1244G |
probably benign |
Het |
| Dhx38 |
T |
C |
8: 110,280,048 (GRCm39) |
D914G |
probably damaging |
Het |
| Dlc1 |
T |
G |
8: 37,404,655 (GRCm39) |
|
probably benign |
Het |
| Eif4a3l1 |
A |
T |
6: 136,306,393 (GRCm39) |
I264F |
probably benign |
Het |
| Fam161b |
A |
G |
12: 84,403,124 (GRCm39) |
S169P |
probably damaging |
Het |
| Fastkd1 |
A |
G |
2: 69,537,725 (GRCm39) |
S286P |
possibly damaging |
Het |
| Fmn2 |
A |
T |
1: 174,409,603 (GRCm39) |
E612V |
unknown |
Het |
| Foxb1 |
T |
A |
9: 69,667,528 (GRCm39) |
M1L |
probably damaging |
Het |
| Gm14412 |
A |
T |
2: 177,007,402 (GRCm39) |
C164* |
probably null |
Het |
| Gm43302 |
T |
A |
5: 105,423,678 (GRCm39) |
M432L |
probably benign |
Het |
| Gm4353 |
C |
A |
7: 115,682,913 (GRCm39) |
A223S |
probably damaging |
Het |
| Gpatch8 |
T |
C |
11: 102,391,693 (GRCm39) |
K143R |
unknown |
Het |
| Gpr15 |
A |
G |
16: 58,538,013 (GRCm39) |
S359P |
probably damaging |
Het |
| Gucy2e |
A |
G |
11: 69,119,207 (GRCm39) |
L649P |
probably damaging |
Het |
| H2-M10.5 |
C |
A |
17: 37,085,473 (GRCm39) |
H211N |
probably damaging |
Het |
| Hs6st1 |
T |
C |
1: 36,142,970 (GRCm39) |
Y302H |
probably damaging |
Het |
| Khdrbs2 |
A |
T |
1: 32,506,851 (GRCm39) |
D165V |
probably damaging |
Het |
| Klra13-ps |
T |
G |
6: 130,281,246 (GRCm39) |
|
noncoding transcript |
Het |
| Lrrc37 |
T |
A |
11: 103,507,880 (GRCm39) |
|
probably benign |
Het |
| Lrrc37a |
T |
A |
11: 103,391,001 (GRCm39) |
T1475S |
probably benign |
Het |
| Maz |
C |
T |
7: 126,624,494 (GRCm39) |
C342Y |
probably damaging |
Het |
| Mcf2l |
C |
A |
8: 13,063,812 (GRCm39) |
S1008* |
probably null |
Het |
| Mcmbp |
T |
C |
7: 128,314,478 (GRCm39) |
D246G |
probably benign |
Het |
| Mipol1 |
G |
A |
12: 57,372,346 (GRCm39) |
R135H |
possibly damaging |
Het |
| Mycbp2 |
T |
A |
14: 103,357,955 (GRCm39) |
Y4613F |
possibly damaging |
Het |
| Nup188 |
G |
A |
2: 30,226,336 (GRCm39) |
A1118T |
probably damaging |
Het |
| Or10g6 |
A |
T |
9: 39,933,964 (GRCm39) |
I92F |
probably damaging |
Het |
| Or2k2 |
T |
A |
4: 58,785,489 (GRCm39) |
I78F |
probably benign |
Het |
| Or4a76 |
G |
A |
2: 89,460,688 (GRCm39) |
L185F |
probably damaging |
Het |
| Or4c121 |
A |
T |
2: 89,024,170 (GRCm39) |
D69E |
possibly damaging |
Het |
| Or4z4 |
A |
G |
19: 12,076,290 (GRCm39) |
S238P |
probably damaging |
Het |
| Or51f1e |
A |
T |
7: 102,747,103 (GRCm39) |
S52C |
probably benign |
Het |
| Or51h7 |
T |
C |
7: 102,591,128 (GRCm39) |
K219E |
probably benign |
Het |
| P3h1 |
T |
A |
4: 119,101,243 (GRCm39) |
I460N |
possibly damaging |
Het |
| Pcnt |
T |
C |
10: 76,245,334 (GRCm39) |
D1101G |
probably benign |
Het |
| Phlpp2 |
C |
A |
8: 110,655,205 (GRCm39) |
Q667K |
possibly damaging |
Het |
| Plec |
A |
G |
15: 76,074,666 (GRCm39) |
F434L |
possibly damaging |
Het |
| Ppp6r2 |
T |
A |
15: 89,164,602 (GRCm39) |
I602N |
probably damaging |
Het |
| Rdh8 |
A |
C |
9: 20,736,475 (GRCm39) |
I181L |
probably benign |
Het |
| Rnf181 |
A |
G |
6: 72,338,505 (GRCm39) |
M1T |
probably null |
Het |
| Rpl29-ps2 |
A |
G |
13: 4,664,221 (GRCm39) |
|
noncoding transcript |
Het |
| Sart3 |
A |
G |
5: 113,883,217 (GRCm39) |
|
probably null |
Het |
| Sec14l2 |
A |
C |
11: 4,059,189 (GRCm39) |
L160R |
probably damaging |
Het |
| Senp1 |
C |
T |
15: 97,946,236 (GRCm39) |
R503H |
probably damaging |
Het |
| Shoc1 |
A |
G |
4: 59,047,399 (GRCm39) |
S1407P |
probably benign |
Het |
| Slc22a2 |
T |
C |
17: 12,827,296 (GRCm39) |
V316A |
probably benign |
Het |
| Slc34a1 |
A |
T |
13: 55,556,898 (GRCm39) |
I365F |
possibly damaging |
Het |
| Spag5 |
T |
C |
11: 78,195,542 (GRCm39) |
V283A |
possibly damaging |
Het |
| Srebf2 |
C |
T |
15: 82,076,456 (GRCm39) |
T702I |
probably benign |
Het |
| Sun3 |
A |
G |
11: 8,981,433 (GRCm39) |
|
probably null |
Het |
| Syt6 |
A |
G |
3: 103,528,217 (GRCm39) |
Y312C |
probably damaging |
Het |
| Tas2r121 |
T |
A |
6: 132,677,756 (GRCm39) |
Y72F |
possibly damaging |
Het |
| Tfrc |
A |
G |
16: 32,442,194 (GRCm39) |
Y473C |
probably damaging |
Het |
| Trp63 |
C |
T |
16: 25,684,935 (GRCm39) |
A274V |
possibly damaging |
Het |
| Trpm5 |
T |
C |
7: 142,626,966 (GRCm39) |
D1085G |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,745,008 (GRCm39) |
V5347A |
probably benign |
Het |
| Uqcc4 |
G |
A |
17: 25,403,963 (GRCm39) |
S101N |
probably damaging |
Het |
| Vma21-ps |
T |
A |
4: 52,496,946 (GRCm39) |
Q100L |
possibly damaging |
Het |
| Vmn2r22 |
T |
C |
6: 123,614,873 (GRCm39) |
N239S |
probably benign |
Het |
| Wfdc8 |
T |
C |
2: 164,439,339 (GRCm39) |
|
probably benign |
Het |
| Xkr4 |
T |
A |
1: 3,741,258 (GRCm39) |
Y105F |
probably damaging |
Het |
| Xpo7 |
C |
T |
14: 70,920,286 (GRCm39) |
V627I |
possibly damaging |
Het |
| Zfp606 |
T |
C |
7: 12,226,479 (GRCm39) |
V200A |
probably benign |
Het |
| Zfp936 |
A |
T |
7: 42,839,858 (GRCm39) |
S441C |
possibly damaging |
Het |
|
| Other mutations in Ly75 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00561:Ly75
|
APN |
2 |
60,206,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01072:Ly75
|
APN |
2 |
60,184,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01409:Ly75
|
APN |
2 |
60,152,036 (GRCm39) |
splice site |
probably null |
|
|
IGL01432:Ly75
|
APN |
2 |
60,206,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01626:Ly75
|
APN |
2 |
60,131,359 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL01690:Ly75
|
APN |
2 |
60,168,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01862:Ly75
|
APN |
2 |
60,129,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01982:Ly75
|
APN |
2 |
60,142,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02075:Ly75
|
APN |
2 |
60,182,700 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02338:Ly75
|
APN |
2 |
60,184,796 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02364:Ly75
|
APN |
2 |
60,188,851 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02456:Ly75
|
APN |
2 |
60,124,125 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02474:Ly75
|
APN |
2 |
60,213,526 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL02608:Ly75
|
APN |
2 |
60,152,244 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL02986:Ly75
|
APN |
2 |
60,138,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03015:Ly75
|
APN |
2 |
60,206,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03049:Ly75
|
APN |
2 |
60,182,414 (GRCm39) |
missense |
probably damaging |
0.99 |
|
euphues
|
UTSW |
2 |
60,129,389 (GRCm39) |
critical splice donor site |
probably null |
|
|
four_score
|
UTSW |
2 |
60,142,115 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
lyly
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
Witty
|
UTSW |
2 |
60,184,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D605:Ly75
|
UTSW |
2 |
60,182,696 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0046:Ly75
|
UTSW |
2 |
60,169,801 (GRCm39) |
intron |
probably benign |
|
|
R0055:Ly75
|
UTSW |
2 |
60,152,262 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0055:Ly75
|
UTSW |
2 |
60,152,262 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,152,163 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,152,163 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0285:Ly75
|
UTSW |
2 |
60,148,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0387:Ly75
|
UTSW |
2 |
60,136,748 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0492:Ly75
|
UTSW |
2 |
60,138,620 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0688:Ly75
|
UTSW |
2 |
60,146,565 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1367:Ly75
|
UTSW |
2 |
60,124,102 (GRCm39) |
splice site |
probably null |
|
|
R1463:Ly75
|
UTSW |
2 |
60,199,101 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1581:Ly75
|
UTSW |
2 |
60,158,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1663:Ly75
|
UTSW |
2 |
60,144,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1818:Ly75
|
UTSW |
2 |
60,142,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1881:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2244:Ly75
|
UTSW |
2 |
60,180,257 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2905:Ly75
|
UTSW |
2 |
60,164,898 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3967:Ly75
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R3968:Ly75
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4039:Ly75
|
UTSW |
2 |
60,183,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4406:Ly75
|
UTSW |
2 |
60,184,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4526:Ly75
|
UTSW |
2 |
60,161,117 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4647:Ly75
|
UTSW |
2 |
60,138,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4795:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4796:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4962:Ly75
|
UTSW |
2 |
60,182,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4979:Ly75
|
UTSW |
2 |
60,206,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5072:Ly75
|
UTSW |
2 |
60,206,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5288:Ly75
|
UTSW |
2 |
60,133,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5373:Ly75
|
UTSW |
2 |
60,142,115 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5374:Ly75
|
UTSW |
2 |
60,142,115 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5384:Ly75
|
UTSW |
2 |
60,164,831 (GRCm39) |
nonsense |
probably null |
|
|
R5385:Ly75
|
UTSW |
2 |
60,133,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5395:Ly75
|
UTSW |
2 |
60,195,455 (GRCm39) |
missense |
probably benign |
0.41 |
|
R5531:Ly75
|
UTSW |
2 |
60,195,489 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5662:Ly75
|
UTSW |
2 |
60,182,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5667:Ly75
|
UTSW |
2 |
60,138,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5671:Ly75
|
UTSW |
2 |
60,138,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5677:Ly75
|
UTSW |
2 |
60,129,426 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5764:Ly75
|
UTSW |
2 |
60,148,783 (GRCm39) |
missense |
probably benign |
|
|
R5896:Ly75
|
UTSW |
2 |
60,213,490 (GRCm39) |
missense |
probably benign |
|
|
R6025:Ly75
|
UTSW |
2 |
60,206,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6113:Ly75
|
UTSW |
2 |
60,199,217 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6448:Ly75
|
UTSW |
2 |
60,129,389 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6601:Ly75
|
UTSW |
2 |
60,148,720 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6745:Ly75
|
UTSW |
2 |
60,138,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6955:Ly75
|
UTSW |
2 |
60,158,217 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R6960:Ly75
|
UTSW |
2 |
60,136,749 (GRCm39) |
missense |
probably benign |
|
|
R7100:Ly75
|
UTSW |
2 |
60,136,778 (GRCm39) |
missense |
probably benign |
|
|
R7110:Ly75
|
UTSW |
2 |
60,206,528 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7203:Ly75
|
UTSW |
2 |
60,154,196 (GRCm39) |
nonsense |
probably null |
|
|
R7291:Ly75
|
UTSW |
2 |
60,160,337 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7308:Ly75
|
UTSW |
2 |
60,164,859 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7447:Ly75
|
UTSW |
2 |
60,164,818 (GRCm39) |
nonsense |
probably null |
|
|
R7512:Ly75
|
UTSW |
2 |
60,164,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7595:Ly75
|
UTSW |
2 |
60,124,171 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7976:Ly75
|
UTSW |
2 |
60,195,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8005:Ly75
|
UTSW |
2 |
60,163,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Ly75
|
UTSW |
2 |
60,144,572 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8392:Ly75
|
UTSW |
2 |
60,180,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8705:Ly75
|
UTSW |
2 |
60,148,729 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8714:Ly75
|
UTSW |
2 |
60,164,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8798:Ly75
|
UTSW |
2 |
60,154,270 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8799:Ly75
|
UTSW |
2 |
60,178,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8834:Ly75
|
UTSW |
2 |
60,161,433 (GRCm39) |
missense |
probably benign |
|
|
R8990:Ly75
|
UTSW |
2 |
60,188,903 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9015:Ly75
|
UTSW |
2 |
60,146,442 (GRCm39) |
missense |
probably benign |
|
|
R9547:Ly75
|
UTSW |
2 |
60,161,069 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9628:Ly75
|
UTSW |
2 |
60,158,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9659:Ly75
|
UTSW |
2 |
60,168,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9660:Ly75
|
UTSW |
2 |
60,154,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9747:Ly75
|
UTSW |
2 |
60,136,672 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0025:Ly75
|
UTSW |
2 |
60,184,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ly75
|
UTSW |
2 |
60,182,477 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
Z1177:Ly75
|
UTSW |
2 |
60,180,348 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCAGGATGACAACCTACGGG -3'
(R):5'- TAGTCAGCGACTAAGGAATACCG -3'
Sequencing Primer
(F):5'- TGACAACCTACGGGATGTTAC -3'
(R):5'- GCTTATCAGCGCGTAAAAGTC -3'
|
| Posted On |
2016-11-09 |
Incidental Mutation