Incidental Mutation 'R0718:Plxnd1'
| ID |
63701 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnd1
|
| Ensembl Gene |
ENSMUSG00000030123 |
| Gene Name |
plexin D1 |
| Synonyms |
6230425C21Rik, b2b1863Clo, b2b553Clo |
| MMRRC Submission |
038900-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0718 (G1)
|
| Quality Score |
160 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
115931772-115971966 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 115943599 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Aspartic acid
at position 1202
(E1202D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000015511
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000015511]
|
| AlphaFold |
Q3UH93 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000015511
AA Change: E1202D
PolyPhen 2
Score 0.676 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000015511
Gene: ENSMUSG00000030123
AA Change: E1202D
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
48 |
N/A |
INTRINSIC |
|
Sema
|
61 |
531 |
6.52e-90 |
SMART |
|
PSI
|
550 |
603 |
6.06e-12 |
SMART |
|
PSI
|
703 |
755 |
1.06e-2 |
SMART |
|
Blast:PSI
|
850 |
891 |
9e-20 |
BLAST |
|
IPT
|
892 |
981 |
4.43e-20 |
SMART |
|
IPT
|
982 |
1068 |
6.61e-19 |
SMART |
|
IPT
|
1070 |
1149 |
6.13e-14 |
SMART |
|
transmembrane domain
|
1271 |
1293 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1345 |
1888 |
5e-238 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131590
|
| SMART Domains |
Protein: ENSMUSP00000115650
Gene: ENSMUSG00000030123
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:PSI
|
2 |
34 |
1e-13 |
BLAST |
|
IPT
|
35 |
124 |
4.43e-20 |
SMART |
|
Blast:IPT
|
125 |
177 |
3e-30 |
BLAST |
|
Pfam:TIG
|
180 |
233 |
4.6e-6 |
PFAM |
|
| Meta Mutation Damage Score |
0.0622 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.8%
- 10x: 97.6%
- 20x: 95.9%
|
| Validation Efficiency |
100% (96/96) |
| MGI Phenotype |
PHENOTYPE: Homozygous null mice display neonatal lethality, thin-walled atria, and vascular abnormalities including abnormal branchial arch artery development, cardiac outflow tract abnormalities, and reduced vascular smooth muscle around some vessels. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamtsl4 |
A |
T |
3: 95,586,918 (GRCm39) |
Y811N |
possibly damaging |
Het |
| Adrm1 |
T |
C |
2: 179,816,940 (GRCm39) |
|
probably benign |
Het |
| Alms1 |
T |
A |
6: 85,598,803 (GRCm39) |
S1210T |
probably benign |
Het |
| Ampd3 |
C |
T |
7: 110,377,015 (GRCm39) |
P11L |
probably damaging |
Het |
| Arhgap5 |
A |
G |
12: 52,563,290 (GRCm39) |
E87G |
possibly damaging |
Het |
| Armc5 |
C |
T |
7: 127,839,242 (GRCm39) |
|
probably benign |
Het |
| Asic2 |
C |
G |
11: 80,862,282 (GRCm39) |
|
probably benign |
Het |
| Asph |
A |
G |
4: 9,514,683 (GRCm39) |
|
probably benign |
Het |
| Bicd2 |
T |
A |
13: 49,531,351 (GRCm39) |
|
probably null |
Het |
| Brip1 |
A |
G |
11: 86,034,131 (GRCm39) |
L530P |
possibly damaging |
Het |
| Bsn |
G |
T |
9: 107,988,559 (GRCm39) |
|
probably benign |
Het |
| Btnl4 |
T |
A |
17: 34,688,608 (GRCm39) |
H390L |
probably benign |
Het |
| Ccdc70 |
A |
C |
8: 22,463,324 (GRCm39) |
K38T |
probably damaging |
Het |
| Ccni |
G |
A |
5: 93,350,175 (GRCm39) |
P35S |
probably benign |
Het |
| Cdh17 |
A |
G |
4: 11,810,451 (GRCm39) |
D714G |
possibly damaging |
Het |
| Cenpf |
A |
G |
1: 189,386,181 (GRCm39) |
L2033P |
probably damaging |
Het |
| Cfap69 |
A |
T |
5: 5,671,924 (GRCm39) |
M328K |
probably damaging |
Het |
| Cmah |
T |
G |
13: 24,601,193 (GRCm39) |
|
probably null |
Het |
| Cog6 |
T |
C |
3: 52,918,050 (GRCm39) |
T163A |
probably benign |
Het |
| Cyp2j8 |
G |
A |
4: 96,389,433 (GRCm39) |
S130F |
probably benign |
Het |
| Dgki |
A |
G |
6: 36,989,831 (GRCm39) |
V636A |
probably damaging |
Het |
| Dmkn |
T |
A |
7: 30,464,211 (GRCm39) |
|
probably benign |
Het |
| Dnah6 |
A |
G |
6: 73,012,276 (GRCm39) |
I3679T |
possibly damaging |
Het |
| Dsp |
A |
T |
13: 38,380,740 (GRCm39) |
Y2495F |
possibly damaging |
Het |
| Exosc4 |
C |
T |
15: 76,213,689 (GRCm39) |
A171V |
probably benign |
Het |
| Fbxw24 |
A |
G |
9: 109,452,577 (GRCm39) |
|
probably benign |
Het |
| Flvcr1 |
A |
T |
1: 190,757,779 (GRCm39) |
L171Q |
probably damaging |
Het |
| Fsd1 |
G |
T |
17: 56,303,445 (GRCm39) |
|
probably null |
Het |
| Gm7732 |
A |
G |
17: 21,350,106 (GRCm39) |
|
noncoding transcript |
Het |
| H2-K2 |
A |
C |
17: 34,194,597 (GRCm39) |
|
noncoding transcript |
Het |
| Hgf |
A |
G |
5: 16,798,857 (GRCm39) |
N295S |
probably damaging |
Het |
| Ift88 |
T |
A |
14: 57,754,870 (GRCm39) |
D811E |
probably benign |
Het |
| Igsf9b |
T |
A |
9: 27,234,657 (GRCm39) |
|
probably null |
Het |
| Immt |
T |
A |
6: 71,840,156 (GRCm39) |
V311E |
probably damaging |
Het |
| Ipo11 |
T |
A |
13: 107,056,119 (GRCm39) |
N51I |
possibly damaging |
Het |
| Isy1 |
T |
C |
6: 87,796,158 (GRCm39) |
K260E |
probably damaging |
Het |
| Jchain |
T |
G |
5: 88,674,061 (GRCm39) |
I28L |
probably benign |
Het |
| Jmjd1c |
T |
A |
10: 67,054,725 (GRCm39) |
|
probably null |
Het |
| Kif13b |
T |
C |
14: 64,989,111 (GRCm39) |
|
probably benign |
Het |
| Klhdc7b |
T |
C |
15: 89,272,372 (GRCm39) |
Y427H |
possibly damaging |
Het |
| Klhl8 |
T |
C |
5: 104,024,159 (GRCm39) |
|
probably benign |
Het |
| Lrp2 |
C |
T |
2: 69,341,292 (GRCm39) |
D963N |
probably damaging |
Het |
| Ltbp3 |
G |
T |
19: 5,796,776 (GRCm39) |
|
probably benign |
Het |
| Ltf |
C |
A |
9: 110,869,447 (GRCm39) |
Q41K |
probably benign |
Het |
| Med4 |
T |
A |
14: 73,754,097 (GRCm39) |
I148N |
probably damaging |
Het |
| Mlh3 |
T |
G |
12: 85,294,471 (GRCm39) |
S1242R |
possibly damaging |
Het |
| Mllt6 |
T |
C |
11: 97,567,185 (GRCm39) |
|
probably benign |
Het |
| Mpdz |
A |
G |
4: 81,210,710 (GRCm39) |
I1712T |
possibly damaging |
Het |
| Mrgprb4 |
T |
A |
7: 47,848,301 (GRCm39) |
H209L |
probably benign |
Het |
| Nkapl |
A |
T |
13: 21,652,610 (GRCm39) |
M1K |
probably null |
Het |
| Nmur2 |
T |
A |
11: 55,920,324 (GRCm39) |
|
probably benign |
Het |
| Nsun2 |
T |
A |
13: 69,691,816 (GRCm39) |
|
probably benign |
Het |
| Or10ag60 |
A |
G |
2: 87,438,271 (GRCm39) |
I180V |
probably benign |
Het |
| Or8k35 |
G |
A |
2: 86,424,425 (GRCm39) |
T249I |
probably benign |
Het |
| Ovgp1 |
T |
C |
3: 105,882,146 (GRCm39) |
|
probably benign |
Het |
| Pcdh8 |
A |
G |
14: 80,008,131 (GRCm39) |
V144A |
possibly damaging |
Het |
| Pcnx3 |
G |
A |
19: 5,727,756 (GRCm39) |
|
probably benign |
Het |
| Pla2r1 |
C |
A |
2: 60,309,874 (GRCm39) |
V570L |
possibly damaging |
Het |
| Ppp1r37 |
T |
C |
7: 19,266,179 (GRCm39) |
E529G |
probably benign |
Het |
| Prdm15 |
A |
G |
16: 97,613,833 (GRCm39) |
F496L |
possibly damaging |
Het |
| Prlhr |
G |
T |
19: 60,456,497 (GRCm39) |
S23* |
probably null |
Het |
| Prlhr |
A |
T |
19: 60,456,443 (GRCm39) |
V41D |
probably benign |
Het |
| Prpf4 |
C |
T |
4: 62,332,777 (GRCm39) |
|
probably benign |
Het |
| Psg26 |
C |
T |
7: 18,209,160 (GRCm39) |
R416H |
probably benign |
Het |
| Psg26 |
T |
C |
7: 18,212,212 (GRCm39) |
H381R |
probably benign |
Het |
| Ralgds |
T |
G |
2: 28,439,128 (GRCm39) |
M717R |
probably benign |
Het |
| Rbms1 |
T |
C |
2: 60,672,756 (GRCm39) |
N44D |
probably damaging |
Het |
| Rpa1 |
T |
C |
11: 75,209,227 (GRCm39) |
|
probably benign |
Het |
| Rprd2 |
T |
C |
3: 95,673,699 (GRCm39) |
N568S |
probably benign |
Het |
| Rptor |
A |
G |
11: 119,763,202 (GRCm39) |
M929V |
probably benign |
Het |
| Rspo1 |
T |
A |
4: 124,900,942 (GRCm39) |
C97S |
possibly damaging |
Het |
| Scin |
C |
T |
12: 40,129,606 (GRCm39) |
G396S |
probably damaging |
Het |
| Scn9a |
T |
C |
2: 66,377,456 (GRCm39) |
N409D |
probably damaging |
Het |
| Sf3b1 |
A |
G |
1: 55,058,544 (GRCm39) |
I15T |
probably damaging |
Het |
| Sh3bp2 |
T |
C |
5: 34,712,839 (GRCm39) |
V149A |
probably damaging |
Het |
| Slc39a12 |
T |
A |
2: 14,412,237 (GRCm39) |
|
probably benign |
Het |
| Sp9 |
G |
T |
2: 73,104,171 (GRCm39) |
A242S |
possibly damaging |
Het |
| Srr |
A |
G |
11: 74,801,891 (GRCm39) |
V126A |
possibly damaging |
Het |
| Tatdn3 |
G |
T |
1: 190,785,046 (GRCm39) |
|
probably benign |
Het |
| Tex14 |
G |
A |
11: 87,390,439 (GRCm39) |
V379I |
probably benign |
Het |
| Tmed6 |
T |
C |
8: 107,788,356 (GRCm39) |
N197S |
probably damaging |
Het |
| Ttbk2 |
A |
T |
2: 120,575,641 (GRCm39) |
I1043N |
probably benign |
Het |
| Ttbk2 |
G |
A |
2: 120,579,056 (GRCm39) |
L689F |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,641,040 (GRCm39) |
S5283P |
probably damaging |
Het |
| Ube3b |
C |
A |
5: 114,540,616 (GRCm39) |
S441* |
probably null |
Het |
| Ush2a |
G |
A |
1: 188,530,027 (GRCm39) |
C3272Y |
probably damaging |
Het |
| Vac14 |
T |
A |
8: 111,359,109 (GRCm39) |
I95K |
probably damaging |
Het |
| Vangl2 |
G |
A |
1: 171,833,784 (GRCm39) |
A433V |
probably damaging |
Het |
| Vwa5b1 |
A |
T |
4: 138,336,135 (GRCm39) |
V153D |
probably damaging |
Het |
| Zfhx3 |
T |
A |
8: 109,682,282 (GRCm39) |
D3240E |
unknown |
Het |
| Zfp945 |
A |
G |
17: 23,070,004 (GRCm39) |
C632R |
probably damaging |
Het |
| Zfyve26 |
G |
A |
12: 79,312,576 (GRCm39) |
|
probably benign |
Het |
| Zyg11b |
A |
T |
4: 108,099,273 (GRCm39) |
I606N |
possibly damaging |
Het |
|
| Other mutations in Plxnd1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00764:Plxnd1
|
APN |
6 |
115,944,933 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01099:Plxnd1
|
APN |
6 |
115,946,906 (GRCm39) |
missense |
probably benign |
|
|
IGL01323:Plxnd1
|
APN |
6 |
115,943,760 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01382:Plxnd1
|
APN |
6 |
115,937,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Plxnd1
|
APN |
6 |
115,936,896 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02244:Plxnd1
|
APN |
6 |
115,955,218 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02272:Plxnd1
|
APN |
6 |
115,970,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02293:Plxnd1
|
APN |
6 |
115,940,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02465:Plxnd1
|
APN |
6 |
115,932,703 (GRCm39) |
makesense |
probably null |
|
|
IGL02873:Plxnd1
|
APN |
6 |
115,936,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03209:Plxnd1
|
APN |
6 |
115,939,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Hiss
|
UTSW |
6 |
115,946,890 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
murmer
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
mutter
|
UTSW |
6 |
115,945,005 (GRCm39) |
missense |
probably benign |
0.27 |
|
rattle
|
UTSW |
6 |
115,936,755 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0357:Plxnd1
|
UTSW |
6 |
115,946,421 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0646:Plxnd1
|
UTSW |
6 |
115,935,660 (GRCm39) |
splice site |
probably benign |
|
|
R0648:Plxnd1
|
UTSW |
6 |
115,970,962 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1116:Plxnd1
|
UTSW |
6 |
115,943,966 (GRCm39) |
splice site |
probably null |
|
|
R1292:Plxnd1
|
UTSW |
6 |
115,939,644 (GRCm39) |
unclassified |
probably benign |
|
|
R1715:Plxnd1
|
UTSW |
6 |
115,945,642 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1760:Plxnd1
|
UTSW |
6 |
115,944,740 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1799:Plxnd1
|
UTSW |
6 |
115,971,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1817:Plxnd1
|
UTSW |
6 |
115,957,562 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1848:Plxnd1
|
UTSW |
6 |
115,943,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1851:Plxnd1
|
UTSW |
6 |
115,940,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Plxnd1
|
UTSW |
6 |
115,946,402 (GRCm39) |
splice site |
probably null |
|
|
R1865:Plxnd1
|
UTSW |
6 |
115,946,402 (GRCm39) |
splice site |
probably null |
|
|
R1875:Plxnd1
|
UTSW |
6 |
115,955,045 (GRCm39) |
splice site |
probably null |
|
|
R1899:Plxnd1
|
UTSW |
6 |
115,946,324 (GRCm39) |
missense |
probably benign |
|
|
R1913:Plxnd1
|
UTSW |
6 |
115,954,978 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1970:Plxnd1
|
UTSW |
6 |
115,939,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2007:Plxnd1
|
UTSW |
6 |
115,944,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2134:Plxnd1
|
UTSW |
6 |
115,934,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2202:Plxnd1
|
UTSW |
6 |
115,939,725 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2230:Plxnd1
|
UTSW |
6 |
115,941,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2267:Plxnd1
|
UTSW |
6 |
115,939,704 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2427:Plxnd1
|
UTSW |
6 |
115,944,709 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4108:Plxnd1
|
UTSW |
6 |
115,936,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4233:Plxnd1
|
UTSW |
6 |
115,942,914 (GRCm39) |
missense |
probably benign |
0.30 |
|
R4280:Plxnd1
|
UTSW |
6 |
115,933,056 (GRCm39) |
splice site |
probably null |
|
|
R4280:Plxnd1
|
UTSW |
6 |
115,933,055 (GRCm39) |
splice site |
probably benign |
|
|
R4346:Plxnd1
|
UTSW |
6 |
115,954,941 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4439:Plxnd1
|
UTSW |
6 |
115,970,937 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4572:Plxnd1
|
UTSW |
6 |
115,932,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4576:Plxnd1
|
UTSW |
6 |
115,945,005 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4599:Plxnd1
|
UTSW |
6 |
115,971,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4614:Plxnd1
|
UTSW |
6 |
115,949,486 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4700:Plxnd1
|
UTSW |
6 |
115,935,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4705:Plxnd1
|
UTSW |
6 |
115,935,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4806:Plxnd1
|
UTSW |
6 |
115,937,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4944:Plxnd1
|
UTSW |
6 |
115,932,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4977:Plxnd1
|
UTSW |
6 |
115,971,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5069:Plxnd1
|
UTSW |
6 |
115,942,862 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5155:Plxnd1
|
UTSW |
6 |
115,935,949 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5460:Plxnd1
|
UTSW |
6 |
115,934,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5729:Plxnd1
|
UTSW |
6 |
115,942,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5909:Plxnd1
|
UTSW |
6 |
115,945,649 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5992:Plxnd1
|
UTSW |
6 |
115,944,748 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6129:Plxnd1
|
UTSW |
6 |
115,955,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6254:Plxnd1
|
UTSW |
6 |
115,954,921 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6273:Plxnd1
|
UTSW |
6 |
115,955,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6310:Plxnd1
|
UTSW |
6 |
115,953,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6732:Plxnd1
|
UTSW |
6 |
115,946,890 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6857:Plxnd1
|
UTSW |
6 |
115,970,724 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7243:Plxnd1
|
UTSW |
6 |
115,949,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7282:Plxnd1
|
UTSW |
6 |
115,937,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7632:Plxnd1
|
UTSW |
6 |
115,953,600 (GRCm39) |
missense |
probably benign |
|
|
R7699:Plxnd1
|
UTSW |
6 |
115,936,755 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7915:Plxnd1
|
UTSW |
6 |
115,943,879 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8090:Plxnd1
|
UTSW |
6 |
115,933,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8382:Plxnd1
|
UTSW |
6 |
115,949,433 (GRCm39) |
missense |
probably benign |
|
|
R8507:Plxnd1
|
UTSW |
6 |
115,943,866 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8539:Plxnd1
|
UTSW |
6 |
115,939,768 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8548:Plxnd1
|
UTSW |
6 |
115,934,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8963:Plxnd1
|
UTSW |
6 |
115,949,506 (GRCm39) |
nonsense |
probably null |
|
|
R9119:Plxnd1
|
UTSW |
6 |
115,932,832 (GRCm39) |
splice site |
probably benign |
|
|
R9177:Plxnd1
|
UTSW |
6 |
115,943,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9182:Plxnd1
|
UTSW |
6 |
115,970,746 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9185:Plxnd1
|
UTSW |
6 |
115,934,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9226:Plxnd1
|
UTSW |
6 |
115,934,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9433:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9449:Plxnd1
|
UTSW |
6 |
115,932,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9451:Plxnd1
|
UTSW |
6 |
115,940,277 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R9599:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9627:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9644:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9672:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
X0024:Plxnd1
|
UTSW |
6 |
115,940,271 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0026:Plxnd1
|
UTSW |
6 |
115,943,745 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
Z1088:Plxnd1
|
UTSW |
6 |
115,944,471 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCGATTTCTGTACCCAGAAGCCG -3'
(R):5'- CTGCAAGGTTCTCAACTCCACACTC -3'
Sequencing Primer
(F):5'- TGAGCAGTGGATGACTCTGT -3'
(R):5'- AGCCCTGAGCAATGCTTC -3'
|
| Posted On |
2013-07-30 |
Incidental Mutation