Incidental Mutation 'IGL01755:Zfp94'
| ID |
153198 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp94
|
| Ensembl Gene |
ENSMUSG00000074282 |
| Gene Name |
zinc finger protein 94 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.085)
|
| Stock # |
IGL01755
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
24001129-24016091 bp(-) (GRCm39) |
| Type of Mutation |
utr 5 prime |
| DNA Base Change (assembly) |
G to A
at 24010906 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000104075
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000032673]
[ENSMUST00000108436]
|
| AlphaFold |
E9Q6Y4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000032673
|
| SMART Domains |
Protein: ENSMUSP00000032673
Gene: ENSMUSG00000074282
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
2 |
59 |
3.06e-19 |
SMART |
|
ZnF_C2H2
|
157 |
179 |
5.06e-2 |
SMART |
|
ZnF_C2H2
|
185 |
207 |
8.47e-4 |
SMART |
|
ZnF_C2H2
|
213 |
235 |
4.72e-2 |
SMART |
|
ZnF_C2H2
|
241 |
263 |
1.28e-3 |
SMART |
|
ZnF_C2H2
|
269 |
291 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
297 |
319 |
9.08e-4 |
SMART |
|
ZnF_C2H2
|
325 |
347 |
2.09e-3 |
SMART |
|
ZnF_C2H2
|
353 |
375 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
381 |
403 |
2.4e-3 |
SMART |
|
ZnF_C2H2
|
409 |
431 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
437 |
459 |
7.9e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108436
|
| SMART Domains |
Protein: ENSMUSP00000104075
Gene: ENSMUSG00000074282
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
8 |
65 |
3.06e-19 |
SMART |
|
ZnF_C2H2
|
163 |
185 |
5.06e-2 |
SMART |
|
ZnF_C2H2
|
191 |
213 |
8.47e-4 |
SMART |
|
ZnF_C2H2
|
219 |
241 |
4.72e-2 |
SMART |
|
ZnF_C2H2
|
247 |
269 |
1.28e-3 |
SMART |
|
ZnF_C2H2
|
275 |
297 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
303 |
325 |
9.08e-4 |
SMART |
|
ZnF_C2H2
|
331 |
353 |
2.09e-3 |
SMART |
|
ZnF_C2H2
|
359 |
381 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
387 |
409 |
2.4e-3 |
SMART |
|
ZnF_C2H2
|
415 |
437 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
443 |
465 |
7.9e-4 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000126580
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000137781
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146817
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154309
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 27 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Atf6 |
A |
G |
1: 170,616,180 (GRCm39) |
I520T |
possibly damaging |
Het |
| Azgp1 |
A |
T |
5: 137,988,109 (GRCm39) |
K297M |
possibly damaging |
Het |
| Cyp2e1 |
A |
G |
7: 140,354,469 (GRCm39) |
|
probably null |
Het |
| Dapk1 |
C |
A |
13: 60,908,989 (GRCm39) |
L1201M |
probably damaging |
Het |
| Dapk1 |
T |
A |
13: 60,908,990 (GRCm39) |
L1201Q |
possibly damaging |
Het |
| Insrr |
A |
T |
3: 87,721,493 (GRCm39) |
D1133V |
probably damaging |
Het |
| Kcnc4 |
T |
C |
3: 107,355,491 (GRCm39) |
N319S |
probably damaging |
Het |
| Kctd1 |
A |
G |
18: 15,195,694 (GRCm39) |
C310R |
possibly damaging |
Het |
| Nefl |
A |
G |
14: 68,323,526 (GRCm39) |
D384G |
probably damaging |
Het |
| Nfatc3 |
A |
G |
8: 106,854,553 (GRCm39) |
N1029S |
probably benign |
Het |
| Nup107 |
T |
C |
10: 117,610,398 (GRCm39) |
Y348C |
probably damaging |
Het |
| Or5b117 |
T |
C |
19: 13,431,179 (GRCm39) |
K234R |
probably damaging |
Het |
| Or5w8 |
T |
A |
2: 87,687,854 (GRCm39) |
C112S |
possibly damaging |
Het |
| Phf8-ps |
T |
A |
17: 33,285,951 (GRCm39) |
N284Y |
probably damaging |
Het |
| Phldb2 |
T |
C |
16: 45,645,945 (GRCm39) |
E212G |
probably damaging |
Het |
| Pirb |
A |
T |
7: 3,720,169 (GRCm39) |
N401K |
probably benign |
Het |
| Plcg2 |
T |
C |
8: 118,347,980 (GRCm39) |
F1183S |
possibly damaging |
Het |
| Plekhf2 |
A |
T |
4: 10,991,308 (GRCm39) |
N11K |
probably damaging |
Het |
| Slc7a11 |
A |
G |
3: 50,378,516 (GRCm39) |
Y241H |
probably benign |
Het |
| Sltm |
T |
G |
9: 70,491,204 (GRCm39) |
|
probably null |
Het |
| Taf4b |
A |
G |
18: 15,031,042 (GRCm39) |
T809A |
probably benign |
Het |
| Taf4b |
C |
A |
18: 15,031,043 (GRCm39) |
T809N |
probably benign |
Het |
| Tesk1 |
T |
C |
4: 43,445,820 (GRCm39) |
|
probably null |
Het |
| Tspan8 |
C |
T |
10: 115,671,203 (GRCm39) |
T120M |
probably damaging |
Het |
| Ttn |
T |
G |
2: 76,551,727 (GRCm39) |
D31275A |
probably damaging |
Het |
| Vcl |
C |
A |
14: 21,046,038 (GRCm39) |
Q334K |
probably damaging |
Het |
| Zkscan17 |
A |
G |
11: 59,378,241 (GRCm39) |
F314S |
probably damaging |
Het |
|
| Other mutations in Zfp94 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02645:Zfp94
|
APN |
7 |
24,003,179 (GRCm39) |
missense |
probably benign |
|
|
R0684:Zfp94
|
UTSW |
7 |
24,002,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1177:Zfp94
|
UTSW |
7 |
24,002,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1644:Zfp94
|
UTSW |
7 |
24,010,927 (GRCm39) |
splice site |
probably benign |
|
|
R1675:Zfp94
|
UTSW |
7 |
24,002,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1826:Zfp94
|
UTSW |
7 |
24,008,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1861:Zfp94
|
UTSW |
7 |
24,008,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3932:Zfp94
|
UTSW |
7 |
24,003,112 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4912:Zfp94
|
UTSW |
7 |
24,003,166 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5663:Zfp94
|
UTSW |
7 |
24,002,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6539:Zfp94
|
UTSW |
7 |
24,002,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7023:Zfp94
|
UTSW |
7 |
24,002,821 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7710:Zfp94
|
UTSW |
7 |
24,003,107 (GRCm39) |
missense |
probably benign |
|
|
R7810:Zfp94
|
UTSW |
7 |
24,002,498 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8134:Zfp94
|
UTSW |
7 |
24,003,166 (GRCm39) |
missense |
probably benign |
0.40 |
|
R8291:Zfp94
|
UTSW |
7 |
24,002,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9421:Zfp94
|
UTSW |
7 |
24,002,978 (GRCm39) |
nonsense |
probably null |
|
|
Z1176:Zfp94
|
UTSW |
7 |
24,003,236 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Posted On |
2014-02-04 |
Incidental Mutation