Incidental Mutation 'IGL00885:Or9i16'
ID 29482
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Or9i16
Ensembl Gene ENSMUSG00000059105
Gene Name olfactory receptor family 9 subfamily I member 16
Synonyms GA_x6K02T2RE5P-4223635-4222688, Olfr1504, MOR212-2
Accession Numbers
Essential gene? Probably non essential (E-score: 0.088) question?
Stock # IGL00885
Quality Score
Chromosome 19
Chromosomal Location 13864625-13865572 bp(-) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) A to T at 13865532 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Methionine to Lysine at position 14 (M14K)
Ref Sequence ENSEMBL: ENSMUSP00000146610 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000078282] [ENSMUST00000209192]
AlphaFold Q8VFQ4
Predicted Effect probably benign
Transcript: ENSMUST00000078282
AA Change: M14K

PolyPhen 2 Score 0.166 (Sensitivity: 0.92; Specificity: 0.87)
SMART Domains Protein: ENSMUSP00000077400
Gene: ENSMUSG00000059105
AA Change: M14K

Pfam:7tm_4 30 307 4.3e-46 PFAM
Pfam:7tm_1 40 313 1.5e-19 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000209192
AA Change: M14K

PolyPhen 2 Score 0.166 (Sensitivity: 0.92; Specificity: 0.87)
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 41 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrf2 A T 17: 43,025,206 (GRCm39) probably benign Het
Adora2a T G 10: 75,169,285 (GRCm39) F250V probably damaging Het
Atp8b5 T C 4: 43,355,567 (GRCm39) S516P probably damaging Het
Btbd16 A G 7: 130,390,552 (GRCm39) I150V probably damaging Het
Capn13 A T 17: 73,646,420 (GRCm39) I331N possibly damaging Het
Capzb A G 4: 139,014,361 (GRCm39) S233G probably benign Het
Clasp2 A G 9: 113,740,484 (GRCm39) R1171G probably damaging Het
Col16a1 T G 4: 129,990,703 (GRCm39) I1419S probably damaging Het
Coro7 T A 16: 4,452,890 (GRCm39) Y286F probably benign Het
Crygd C T 1: 65,101,250 (GRCm39) R115Q probably benign Het
Cyp11b2 T C 15: 74,725,364 (GRCm39) T252A probably benign Het
Daam1 T A 12: 71,990,865 (GRCm39) C160S unknown Het
Ephx4 T C 5: 107,553,991 (GRCm39) probably benign Het
Fbxo47 A T 11: 97,768,946 (GRCm39) D63E probably benign Het
Fgf3 A T 7: 144,394,521 (GRCm39) probably benign Het
Fstl4 C T 11: 53,039,809 (GRCm39) T331I possibly damaging Het
Gpr158 T C 2: 21,653,832 (GRCm39) F467S probably damaging Het
Igfbpl1 C T 4: 45,826,478 (GRCm39) V106I probably damaging Het
Ikzf2 T C 1: 69,578,481 (GRCm39) T271A possibly damaging Het
Kat14 T A 2: 144,236,175 (GRCm39) N302K probably benign Het
Kmt2c G T 5: 25,614,169 (GRCm39) Q184K possibly damaging Het
Moxd2 A G 6: 40,861,113 (GRCm39) probably benign Het
Nbeal2 C A 9: 110,467,729 (GRCm39) E479D probably damaging Het
Neo1 A G 9: 58,795,746 (GRCm39) L1231P probably damaging Het
Nfatc3 C T 8: 106,825,809 (GRCm39) P620L probably damaging Het
Nol9 T C 4: 152,126,057 (GRCm39) F253L probably damaging Het
Nutm2 T A 13: 50,628,896 (GRCm39) S653R probably benign Het
Or2n1e A C 17: 38,585,790 (GRCm39) I43L probably benign Het
Plcg1 A G 2: 160,600,003 (GRCm39) D921G probably benign Het
Plpp4 A T 7: 128,923,257 (GRCm39) I101F probably damaging Het
Psg17 A T 7: 18,554,091 (GRCm39) L53Q probably damaging Het
Ptpn4 A T 1: 119,730,093 (GRCm39) I20N possibly damaging Het
R3hdm1 A T 1: 128,164,175 (GRCm39) I1030L probably damaging Het
Rpl7 A C 1: 16,172,807 (GRCm39) S171A possibly damaging Het
Snx25 G A 8: 46,491,513 (GRCm39) T859M probably damaging Het
Spata31e5 T C 1: 28,815,926 (GRCm39) E702G unknown Het
Tmem94 A G 11: 115,686,154 (GRCm39) M990V probably damaging Het
Tnnt2 A G 1: 135,774,502 (GRCm39) probably benign Het
Ttn T C 2: 76,540,029 (GRCm39) H34319R possibly damaging Het
Vmn1r72 A G 7: 11,404,424 (GRCm39) V8A probably benign Het
Zbtb41 A G 1: 139,358,062 (GRCm39) T457A probably benign Het
Other mutations in Or9i16
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00332:Or9i16 APN 19 13,864,945 (GRCm39) missense probably benign
IGL01084:Or9i16 APN 19 13,864,866 (GRCm39) missense probably damaging 1.00
IGL01522:Or9i16 APN 19 13,864,722 (GRCm39) nonsense probably null
IGL01727:Or9i16 APN 19 13,865,242 (GRCm39) missense probably damaging 0.98
IGL02440:Or9i16 APN 19 13,865,223 (GRCm39) missense probably damaging 1.00
IGL03342:Or9i16 APN 19 13,864,801 (GRCm39) missense probably damaging 1.00
R0531:Or9i16 UTSW 19 13,865,116 (GRCm39) missense possibly damaging 0.62
R0577:Or9i16 UTSW 19 13,865,167 (GRCm39) missense probably damaging 1.00
R1028:Or9i16 UTSW 19 13,865,159 (GRCm39) missense probably damaging 0.97
R1674:Or9i16 UTSW 19 13,864,954 (GRCm39) missense probably benign 0.01
R3906:Or9i16 UTSW 19 13,865,070 (GRCm39) missense probably damaging 1.00
R4598:Or9i16 UTSW 19 13,865,381 (GRCm39) missense probably damaging 1.00
R4658:Or9i16 UTSW 19 13,864,912 (GRCm39) missense probably benign 0.19
R4676:Or9i16 UTSW 19 13,864,765 (GRCm39) missense probably damaging 1.00
R5919:Or9i16 UTSW 19 13,865,209 (GRCm39) missense probably damaging 1.00
R5943:Or9i16 UTSW 19 13,865,116 (GRCm39) missense possibly damaging 0.62
R8112:Or9i16 UTSW 19 13,864,753 (GRCm39) missense probably damaging 1.00
R9616:Or9i16 UTSW 19 13,864,861 (GRCm39) missense probably damaging 1.00
Posted On 2013-04-17