Incidental Mutation 'IGL00336:Fut10'
ID 6232
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Fut10
Ensembl Gene ENSMUSG00000046152
Gene Name fucosyltransferase 10
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.116) question?
Stock # IGL00336
Quality Score
Status
Chromosome 8
Chromosomal Location 31187331-31261738 bp(+) (GRCm38)
Type of Mutation critical splice donor site (2 bp from exon)
DNA Base Change (assembly) T to A at 31195291 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000124437 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000066173] [ENSMUST00000110527] [ENSMUST00000161502] [ENSMUST00000161788]
AlphaFold Q5F2L2
Predicted Effect probably null
Transcript: ENSMUST00000066173
SMART Domains Protein: ENSMUSP00000069816
Gene: ENSMUSG00000046152

DomainStartEndE-ValueType
transmembrane domain 9 31 N/A INTRINSIC
Pfam:Glyco_tran_10_N 79 184 5e-13 PFAM
Pfam:Glyco_transf_10 209 410 7.9e-38 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000110527
SMART Domains Protein: ENSMUSP00000106156
Gene: ENSMUSG00000046152

DomainStartEndE-ValueType
Pfam:Glyco_transf_10 7 134 3e-9 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000161502
SMART Domains Protein: ENSMUSP00000125265
Gene: ENSMUSG00000046152

DomainStartEndE-ValueType
Pfam:Glyco_transf_10 7 412 4.1e-92 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000161788
SMART Domains Protein: ENSMUSP00000124437
Gene: ENSMUSG00000046152

DomainStartEndE-ValueType
Pfam:Glyco_transf_10 7 411 1.3e-92 PFAM
low complexity region 418 429 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 59 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2010111I01Rik A T 13: 63,015,423 D86V possibly damaging Het
A430033K04Rik A G 5: 138,647,104 Y417C probably damaging Het
Adam28 T A 14: 68,622,120 H548L possibly damaging Het
AF529169 T C 9: 89,603,143 D67G probably damaging Het
Agbl3 A T 6: 34,846,836 D812V probably damaging Het
Aox1 T A 1: 58,059,044 L305Q probably damaging Het
Arhgef38 A G 3: 133,132,051 V706A probably benign Het
Arl15 A G 13: 114,154,752 I171V probably benign Het
Cacna1s C A 1: 136,084,273 Y237* probably null Het
Ccnt1 T C 15: 98,565,109 T61A possibly damaging Het
Col25a1 T A 3: 130,181,784 probably benign Het
Col4a1 T A 8: 11,240,077 probably benign Het
Dcun1d1 T C 3: 35,916,306 E130G possibly damaging Het
Dnah7b G A 1: 46,142,149 M1065I probably benign Het
Ephb2 T G 4: 136,657,484 K872T probably damaging Het
Fga G A 3: 83,031,674 G452D probably damaging Het
Flrt1 T A 19: 7,096,912 N90I probably damaging Het
Gm4553 T C 7: 142,165,227 S155G unknown Het
Gpr137b T C 13: 13,374,415 probably benign Het
Gprc5d G A 6: 135,116,490 Q140* probably null Het
Ifi27l2b T C 12: 103,451,217 K237R unknown Het
Ipo8 A T 6: 148,782,786 M836K possibly damaging Het
Kcnq4 G A 4: 120,698,016 Q657* probably null Het
Lama1 A T 17: 67,813,948 H2693L probably benign Het
Lrrc23 A G 6: 124,778,926 W40R probably damaging Het
Morn2 C A 17: 80,295,504 probably benign Het
Ms4a6b T A 19: 11,529,490 N214K possibly damaging Het
Nags A T 11: 102,149,066 S527C probably damaging Het
Ndst1 C T 18: 60,707,956 G218D probably damaging Het
Olfr1097 C T 2: 86,890,245 C310Y probably benign Het
Olfr1442 T A 19: 12,674,560 Y118* probably null Het
Olfr16 G A 1: 172,957,478 V228M probably benign Het
Oxa1l G T 14: 54,363,345 G92* probably null Het
Parp16 A T 9: 65,229,963 E157V probably damaging Het
Pcdh17 A T 14: 84,447,544 I484F probably damaging Het
Pex16 A G 2: 92,379,235 R263G probably benign Het
Pkd1l3 G A 8: 109,630,237 E765K possibly damaging Het
Plce1 T C 19: 38,651,906 V532A probably damaging Het
Polq A G 16: 37,065,247 probably benign Het
Pramel5 T C 4: 144,271,621 T351A probably damaging Het
Prokr1 A T 6: 87,588,611 I84N probably damaging Het
Prss30 A T 17: 23,973,721 S162T probably benign Het
Ranbp2 A G 10: 58,451,984 K25E probably damaging Het
Rapsn A G 2: 91,035,860 T22A probably damaging Het
Rhoj G T 12: 75,308,906 G9V probably damaging Het
Rnf213 A G 11: 119,449,343 R3467G probably benign Het
Rreb1 C A 13: 37,929,646 S327* probably null Het
Scn5a G A 9: 119,486,224 P1806L probably damaging Het
Sema6a C A 18: 47,289,975 probably null Het
Stag3 G A 5: 138,297,659 E416K probably benign Het
Stpg1 T A 4: 135,529,545 S216T possibly damaging Het
Tfeb C A 17: 47,791,664 N426K probably benign Het
Trp53bp1 G T 2: 121,256,579 Q199K possibly damaging Het
Ubr4 A G 4: 139,428,566 D2234G probably damaging Het
Ush1c T G 7: 46,196,770 Q866P probably benign Het
Vdr T A 15: 97,884,854 D29V probably damaging Het
Vps13c T C 9: 67,945,942 V2439A probably benign Het
Xirp2 T C 2: 67,512,598 S1728P possibly damaging Het
Zfp9 A G 6: 118,464,475 S409P probably damaging Het
Other mutations in Fut10
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00566:Fut10 APN 8 31235684 missense probably damaging 1.00
IGL00858:Fut10 APN 8 31235705 missense probably damaging 0.97
IGL00861:Fut10 APN 8 31235705 missense probably damaging 0.97
IGL00862:Fut10 APN 8 31235705 missense probably damaging 0.97
IGL01916:Fut10 APN 8 31235706 missense probably benign 0.01
IGL02030:Fut10 APN 8 31235978 nonsense probably null
IGL02318:Fut10 APN 8 31236258 missense probably damaging 1.00
IGL02354:Fut10 APN 8 31201370 missense probably damaging 0.99
IGL02361:Fut10 APN 8 31201370 missense probably damaging 0.99
IGL02932:Fut10 APN 8 31259937 missense probably damaging 1.00
IGL03345:Fut10 APN 8 31260041 missense probably damaging 1.00
R0234:Fut10 UTSW 8 31236197 missense probably damaging 1.00
R0234:Fut10 UTSW 8 31236197 missense probably damaging 1.00
R1728:Fut10 UTSW 8 31201390 missense probably benign 0.00
R1729:Fut10 UTSW 8 31201390 missense probably benign 0.00
R1845:Fut10 UTSW 8 31236300 missense probably damaging 1.00
R2173:Fut10 UTSW 8 31236131 missense probably damaging 1.00
R2518:Fut10 UTSW 8 31236467 missense probably benign 0.19
R3692:Fut10 UTSW 8 31236020 missense possibly damaging 0.94
R4449:Fut10 UTSW 8 31236257 missense probably damaging 1.00
R5015:Fut10 UTSW 8 31236120 missense probably damaging 0.96
R5942:Fut10 UTSW 8 31201457 missense possibly damaging 0.62
R6497:Fut10 UTSW 8 31236250 missense probably damaging 0.99
R7566:Fut10 UTSW 8 31259922 missense probably benign 0.00
R7645:Fut10 UTSW 8 31236204 missense possibly damaging 0.92
R8127:Fut10 UTSW 8 31194971 start gained probably benign
R8241:Fut10 UTSW 8 31260006 nonsense probably null
R8899:Fut10 UTSW 8 31236486 missense possibly damaging 0.46
R9314:Fut10 UTSW 8 31201476 missense probably damaging 0.98
Posted On 2012-04-20