Incidental Mutation 'R1911:Psme4'
| ID |
210291 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Psme4
|
| Ensembl Gene |
ENSMUSG00000040850 |
| Gene Name |
proteasome (prosome, macropain) activator subunit 4 |
| Synonyms |
|
| MMRRC Submission |
039929-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1911 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
30721726-30830361 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 30765658 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Alanine
at position 587
(S587A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000045460
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041231]
|
| AlphaFold |
Q5SSW2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041231
AA Change: S587A
PolyPhen 2
Score 0.017 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000045460
Gene: ENSMUSG00000040850
AA Change: S587A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
122 |
133 |
N/A |
INTRINSIC |
|
Pfam:BLM10_mid
|
330 |
828 |
8.8e-119 |
PFAM |
|
SCOP:d1b3ua_
|
1183 |
1716 |
3e-14 |
SMART |
|
Pfam:DUF3437
|
1756 |
1843 |
5.3e-39 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133430
|
| Meta Mutation Damage Score |
0.0718 |
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.8%
- 10x: 95.4%
- 20x: 93.2%
|
| Validation Efficiency |
99% (99/100) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele show normal repair of DNA double-strand breaks but exhibit significantly reduced male fertility due to defects in spermatogenesis observed in both meiotic spermatocytes and postmeiotic haploid spermatids. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(25) : Targeted, knock-out(1) Gene trapped(24) |
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930590J08Rik |
T |
A |
6: 91,927,050 (GRCm39) |
|
probably benign |
Het |
| Abca7 |
T |
C |
10: 79,842,468 (GRCm39) |
V1134A |
probably benign |
Het |
| Acaa2 |
A |
G |
18: 74,925,483 (GRCm39) |
E82G |
probably benign |
Het |
| Acap1 |
T |
C |
11: 69,772,548 (GRCm39) |
D521G |
probably damaging |
Het |
| Adam19 |
T |
C |
11: 46,012,281 (GRCm39) |
V259A |
probably damaging |
Het |
| Adss1 |
T |
C |
12: 112,599,443 (GRCm39) |
V140A |
probably benign |
Het |
| Aif1 |
G |
A |
17: 35,391,127 (GRCm39) |
P44L |
probably benign |
Het |
| Aldh3b1 |
T |
G |
19: 3,971,187 (GRCm39) |
D159A |
probably damaging |
Het |
| Ank1 |
T |
C |
8: 23,589,666 (GRCm39) |
V589A |
probably damaging |
Het |
| Ano2 |
G |
A |
6: 125,990,654 (GRCm39) |
D803N |
probably benign |
Het |
| Arid1b |
A |
G |
17: 5,393,241 (GRCm39) |
E2257G |
probably damaging |
Het |
| Asb17 |
T |
C |
3: 153,550,138 (GRCm39) |
Y57H |
probably benign |
Het |
| Asph |
T |
C |
4: 9,453,335 (GRCm39) |
E646G |
probably damaging |
Het |
| Aspm |
T |
A |
1: 139,405,832 (GRCm39) |
I1573K |
probably benign |
Het |
| Bcas1 |
C |
A |
2: 170,229,863 (GRCm39) |
D236Y |
probably damaging |
Het |
| Bcas2 |
G |
T |
3: 103,079,113 (GRCm39) |
G9* |
probably null |
Het |
| Btaf1 |
A |
G |
19: 36,964,030 (GRCm39) |
Q867R |
probably benign |
Het |
| Calhm3 |
C |
T |
19: 47,143,908 (GRCm39) |
V132I |
possibly damaging |
Het |
| Ccer1 |
A |
T |
10: 97,530,539 (GRCm39) |
I401F |
possibly damaging |
Het |
| Cdcp3 |
T |
C |
7: 130,839,818 (GRCm39) |
V580A |
probably damaging |
Het |
| Cecr2 |
T |
A |
6: 120,739,526 (GRCm39) |
|
probably benign |
Het |
| Cep104 |
G |
A |
4: 154,091,255 (GRCm39) |
R925Q |
possibly damaging |
Het |
| Cep164 |
T |
A |
9: 45,682,104 (GRCm39) |
M1900L |
probably benign |
Het |
| Crybg1 |
A |
G |
10: 43,873,673 (GRCm39) |
V1145A |
possibly damaging |
Het |
| Cyp2a4 |
T |
A |
7: 26,008,399 (GRCm39) |
N180K |
possibly damaging |
Het |
| Dennd4a |
T |
C |
9: 64,796,368 (GRCm39) |
L798P |
probably damaging |
Het |
| Dmxl1 |
T |
C |
18: 50,011,230 (GRCm39) |
I1129T |
probably benign |
Het |
| Dnah2 |
T |
C |
11: 69,406,578 (GRCm39) |
N555D |
possibly damaging |
Het |
| Dock1 |
T |
A |
7: 134,601,029 (GRCm39) |
M988K |
probably damaging |
Het |
| Elp4 |
T |
A |
2: 105,533,088 (GRCm39) |
H419L |
probably damaging |
Het |
| Endov |
T |
C |
11: 119,393,177 (GRCm39) |
V109A |
possibly damaging |
Het |
| Epha8 |
T |
C |
4: 136,663,625 (GRCm39) |
Y477C |
probably damaging |
Het |
| Erlin1 |
A |
G |
19: 44,037,561 (GRCm39) |
M188T |
probably damaging |
Het |
| Fhip1a |
T |
A |
3: 85,568,525 (GRCm39) |
D998V |
probably benign |
Het |
| Fhod3 |
A |
T |
18: 25,245,643 (GRCm39) |
D1231V |
possibly damaging |
Het |
| Gimap3 |
T |
A |
6: 48,742,646 (GRCm39) |
I95F |
possibly damaging |
Het |
| Gm10717 |
T |
G |
9: 3,026,317 (GRCm39) |
F205C |
probably damaging |
Het |
| Grk1 |
C |
A |
8: 13,457,923 (GRCm39) |
D274E |
probably damaging |
Het |
| Gsdmc2 |
G |
A |
15: 63,699,621 (GRCm39) |
A269V |
probably benign |
Het |
| Krt33a |
T |
A |
11: 99,903,175 (GRCm39) |
Q289L |
probably benign |
Het |
| Krt76 |
T |
A |
15: 101,796,600 (GRCm39) |
K403* |
probably null |
Het |
| Lcn4 |
T |
C |
2: 26,560,607 (GRCm39) |
|
probably benign |
Het |
| Mab21l1 |
T |
C |
3: 55,691,048 (GRCm39) |
S212P |
possibly damaging |
Het |
| Mapk8ip3 |
A |
C |
17: 25,123,025 (GRCm39) |
D610E |
probably benign |
Het |
| Mastl |
G |
T |
2: 23,022,692 (GRCm39) |
S677* |
probably null |
Het |
| Mfap3 |
T |
C |
11: 57,420,562 (GRCm39) |
F181S |
probably damaging |
Het |
| Mlkl |
T |
C |
8: 112,038,732 (GRCm39) |
|
probably benign |
Het |
| Mov10 |
G |
A |
3: 104,708,876 (GRCm39) |
|
probably benign |
Het |
| Muc5ac |
T |
C |
7: 141,350,041 (GRCm39) |
F595L |
probably benign |
Het |
| Nbas |
T |
A |
12: 13,616,145 (GRCm39) |
C2228S |
probably benign |
Het |
| Nit2 |
G |
A |
16: 56,982,046 (GRCm39) |
|
probably benign |
Het |
| Nod1 |
C |
T |
6: 54,921,425 (GRCm39) |
V298M |
probably damaging |
Het |
| Or3a4 |
C |
A |
11: 73,945,210 (GRCm39) |
R125L |
probably damaging |
Het |
| Or4c111 |
A |
G |
2: 88,843,565 (GRCm39) |
L281P |
probably damaging |
Het |
| Or52b1 |
T |
A |
7: 104,978,590 (GRCm39) |
I270F |
probably benign |
Het |
| Or6c210 |
A |
T |
10: 129,495,981 (GRCm39) |
D102V |
probably benign |
Het |
| Or7g12 |
T |
C |
9: 18,900,196 (GRCm39) |
L304P |
probably damaging |
Het |
| Osbpl5 |
C |
A |
7: 143,243,662 (GRCm39) |
R864L |
probably benign |
Het |
| Pcnt |
G |
A |
10: 76,204,650 (GRCm39) |
T2585M |
possibly damaging |
Het |
| Pepd |
C |
T |
7: 34,634,174 (GRCm39) |
|
probably benign |
Het |
| Pou6f2 |
T |
C |
13: 18,326,548 (GRCm39) |
I341V |
probably damaging |
Het |
| Pramel32 |
T |
C |
4: 88,548,309 (GRCm39) |
Q32R |
possibly damaging |
Het |
| Prune2 |
T |
A |
19: 17,091,038 (GRCm39) |
F281I |
probably benign |
Het |
| Psg19 |
T |
G |
7: 18,528,193 (GRCm39) |
Q183H |
probably damaging |
Het |
| Ptpro |
T |
C |
6: 137,377,617 (GRCm39) |
|
probably benign |
Het |
| Pttg1ip2 |
C |
A |
5: 5,502,019 (GRCm39) |
W144C |
probably benign |
Het |
| Rasgrp4 |
T |
C |
7: 28,838,302 (GRCm39) |
V92A |
probably damaging |
Het |
| Rem1 |
G |
A |
2: 152,476,455 (GRCm39) |
V238M |
probably damaging |
Het |
| Rexo5 |
C |
T |
7: 119,398,867 (GRCm39) |
A68V |
probably damaging |
Het |
| Robo2 |
A |
T |
16: 73,755,213 (GRCm39) |
N769K |
probably damaging |
Het |
| Sfrp5 |
C |
T |
19: 42,187,237 (GRCm39) |
V278I |
probably benign |
Het |
| Sidt1 |
A |
G |
16: 44,102,234 (GRCm39) |
S309P |
possibly damaging |
Het |
| Slc22a6 |
A |
C |
19: 8,599,246 (GRCm39) |
Q292H |
probably benign |
Het |
| Slc4a3 |
G |
A |
1: 75,530,367 (GRCm39) |
R690H |
probably damaging |
Het |
| Snx7 |
A |
T |
3: 117,623,317 (GRCm39) |
|
probably null |
Het |
| Spag6 |
T |
A |
2: 18,720,616 (GRCm39) |
Y129* |
probably null |
Het |
| Srcap |
T |
C |
7: 127,133,994 (GRCm39) |
I905T |
probably damaging |
Het |
| St6gal1 |
T |
G |
16: 23,140,383 (GRCm39) |
S185A |
probably damaging |
Het |
| Sult6b1 |
G |
A |
17: 79,196,393 (GRCm39) |
H250Y |
possibly damaging |
Het |
| Tdrd6 |
T |
G |
17: 43,937,979 (GRCm39) |
N1023T |
probably benign |
Het |
| Tecta |
C |
T |
9: 42,249,232 (GRCm39) |
E1877K |
probably damaging |
Het |
| Tex10 |
C |
T |
4: 48,456,800 (GRCm39) |
R637Q |
probably benign |
Het |
| Tex14 |
T |
A |
11: 87,385,861 (GRCm39) |
D240E |
probably damaging |
Het |
| Tex47 |
T |
C |
5: 7,355,022 (GRCm39) |
Y68H |
probably damaging |
Het |
| Thbs2 |
A |
G |
17: 14,910,104 (GRCm39) |
V165A |
probably benign |
Het |
| Tmem126b |
T |
A |
7: 90,118,367 (GRCm39) |
Y171F |
possibly damaging |
Het |
| Tpsg1 |
G |
T |
17: 25,592,374 (GRCm39) |
M46I |
probably benign |
Het |
| Trmt2a |
A |
G |
16: 18,069,070 (GRCm39) |
K304R |
probably benign |
Het |
| Ttc28 |
G |
T |
5: 111,428,616 (GRCm39) |
R1845L |
possibly damaging |
Het |
| Umodl1 |
A |
T |
17: 31,211,128 (GRCm39) |
T884S |
possibly damaging |
Het |
| Vmn2r77 |
A |
G |
7: 86,461,001 (GRCm39) |
K776E |
probably damaging |
Het |
| Vmn2r88 |
T |
C |
14: 51,655,671 (GRCm39) |
S627P |
probably damaging |
Het |
| Vrk1 |
T |
C |
12: 106,024,236 (GRCm39) |
|
probably null |
Het |
| Zfp644 |
A |
G |
5: 106,783,137 (GRCm39) |
M1079T |
possibly damaging |
Het |
| Znrf1 |
T |
C |
8: 112,348,233 (GRCm39) |
*41Q |
probably null |
Het |
| Znrf1 |
T |
C |
8: 112,348,244 (GRCm39) |
F183L |
possibly damaging |
Het |
|
| Other mutations in Psme4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00228:Psme4
|
APN |
11 |
30,765,710 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00401:Psme4
|
APN |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
IGL00475:Psme4
|
APN |
11 |
30,795,252 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL00576:Psme4
|
APN |
11 |
30,773,145 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL00817:Psme4
|
APN |
11 |
30,770,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01525:Psme4
|
APN |
11 |
30,759,936 (GRCm39) |
splice site |
probably benign |
|
|
IGL01862:Psme4
|
APN |
11 |
30,762,038 (GRCm39) |
nonsense |
probably null |
|
|
IGL02310:Psme4
|
APN |
11 |
30,787,484 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02477:Psme4
|
APN |
11 |
30,792,083 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02545:Psme4
|
APN |
11 |
30,791,586 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02608:Psme4
|
APN |
11 |
30,770,944 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL02621:Psme4
|
APN |
11 |
30,798,131 (GRCm39) |
missense |
probably benign |
|
|
IGL02822:Psme4
|
APN |
11 |
30,798,204 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02833:Psme4
|
APN |
11 |
30,800,715 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02964:Psme4
|
APN |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
IGL03273:Psme4
|
APN |
11 |
30,798,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03348:Psme4
|
APN |
11 |
30,826,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03382:Psme4
|
APN |
11 |
30,757,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
H2330:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
PIT4378001:Psme4
|
UTSW |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
R0276:Psme4
|
UTSW |
11 |
30,761,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0462:Psme4
|
UTSW |
11 |
30,798,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0685:Psme4
|
UTSW |
11 |
30,828,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0766:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R0830:Psme4
|
UTSW |
11 |
30,757,797 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0940:Psme4
|
UTSW |
11 |
30,765,264 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1018:Psme4
|
UTSW |
11 |
30,754,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1312:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R1448:Psme4
|
UTSW |
11 |
30,802,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1713:Psme4
|
UTSW |
11 |
30,756,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1732:Psme4
|
UTSW |
11 |
30,798,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1813:Psme4
|
UTSW |
11 |
30,754,353 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1905:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1907:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1956:Psme4
|
UTSW |
11 |
30,782,424 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1974:Psme4
|
UTSW |
11 |
30,769,011 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1980:Psme4
|
UTSW |
11 |
30,782,615 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1986:Psme4
|
UTSW |
11 |
30,780,352 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2046:Psme4
|
UTSW |
11 |
30,767,723 (GRCm39) |
splice site |
probably benign |
|
|
R2142:Psme4
|
UTSW |
11 |
30,770,998 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2698:Psme4
|
UTSW |
11 |
30,824,282 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2844:Psme4
|
UTSW |
11 |
30,795,173 (GRCm39) |
splice site |
probably benign |
|
|
R3807:Psme4
|
UTSW |
11 |
30,806,027 (GRCm39) |
splice site |
probably null |
|
|
R3876:Psme4
|
UTSW |
11 |
30,806,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4420:Psme4
|
UTSW |
11 |
30,762,028 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4584:Psme4
|
UTSW |
11 |
30,784,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4615:Psme4
|
UTSW |
11 |
30,784,287 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4714:Psme4
|
UTSW |
11 |
30,782,573 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5008:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R5109:Psme4
|
UTSW |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
R5155:Psme4
|
UTSW |
11 |
30,826,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5199:Psme4
|
UTSW |
11 |
30,803,272 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5205:Psme4
|
UTSW |
11 |
30,782,666 (GRCm39) |
intron |
probably benign |
|
|
R5452:Psme4
|
UTSW |
11 |
30,741,168 (GRCm39) |
missense |
probably benign |
|
|
R5491:Psme4
|
UTSW |
11 |
30,765,246 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5685:Psme4
|
UTSW |
11 |
30,759,837 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5764:Psme4
|
UTSW |
11 |
30,722,364 (GRCm39) |
intron |
probably benign |
|
|
R5853:Psme4
|
UTSW |
11 |
30,741,234 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5865:Psme4
|
UTSW |
11 |
30,741,993 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5903:Psme4
|
UTSW |
11 |
30,791,589 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5927:Psme4
|
UTSW |
11 |
30,754,294 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6004:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R6102:Psme4
|
UTSW |
11 |
30,815,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Psme4
|
UTSW |
11 |
30,803,245 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6527:Psme4
|
UTSW |
11 |
30,782,175 (GRCm39) |
missense |
probably benign |
|
|
R6750:Psme4
|
UTSW |
11 |
30,803,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6885:Psme4
|
UTSW |
11 |
30,784,307 (GRCm39) |
nonsense |
probably null |
|
|
R6939:Psme4
|
UTSW |
11 |
30,787,291 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6945:Psme4
|
UTSW |
11 |
30,787,437 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7029:Psme4
|
UTSW |
11 |
30,722,474 (GRCm39) |
intron |
probably benign |
|
|
R7049:Psme4
|
UTSW |
11 |
30,763,904 (GRCm39) |
splice site |
probably null |
|
|
R7098:Psme4
|
UTSW |
11 |
30,800,661 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7107:Psme4
|
UTSW |
11 |
30,798,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7223:Psme4
|
UTSW |
11 |
30,824,226 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7319:Psme4
|
UTSW |
11 |
30,757,790 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7375:Psme4
|
UTSW |
11 |
30,722,700 (GRCm39) |
splice site |
probably null |
|
|
R7410:Psme4
|
UTSW |
11 |
30,765,279 (GRCm39) |
nonsense |
probably null |
|
|
R7469:Psme4
|
UTSW |
11 |
30,752,837 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7651:Psme4
|
UTSW |
11 |
30,787,334 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7679:Psme4
|
UTSW |
11 |
30,828,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7681:Psme4
|
UTSW |
11 |
30,741,975 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7822:Psme4
|
UTSW |
11 |
30,824,245 (GRCm39) |
missense |
probably benign |
|
|
R8013:Psme4
|
UTSW |
11 |
30,754,320 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8130:Psme4
|
UTSW |
11 |
30,792,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8323:Psme4
|
UTSW |
11 |
30,793,532 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8330:Psme4
|
UTSW |
11 |
30,793,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8363:Psme4
|
UTSW |
11 |
30,762,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8491:Psme4
|
UTSW |
11 |
30,722,161 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8690:Psme4
|
UTSW |
11 |
30,787,319 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8696:Psme4
|
UTSW |
11 |
30,759,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8743:Psme4
|
UTSW |
11 |
30,828,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8998:Psme4
|
UTSW |
11 |
30,788,957 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9241:Psme4
|
UTSW |
11 |
30,815,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Psme4
|
UTSW |
11 |
30,788,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9736:Psme4
|
UTSW |
11 |
30,797,411 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9744:Psme4
|
UTSW |
11 |
30,765,294 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9746:Psme4
|
UTSW |
11 |
30,826,868 (GRCm39) |
nonsense |
probably null |
|
|
V5088:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
X0063:Psme4
|
UTSW |
11 |
30,782,600 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
Z1176:Psme4
|
UTSW |
11 |
30,793,522 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Psme4
|
UTSW |
11 |
30,762,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Psme4
|
UTSW |
11 |
30,756,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCTAAGGTTGGTACTGTGAAG -3'
(R):5'- TGCAGACACATTTCAATGAGGATG -3'
Sequencing Primer
(F):5'- GGTTGGTACTGTGAAGTCTATTTATG -3'
(R):5'- CACATTTCAATGAGGATGAACAACG -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation