Incidental Mutation 'IGL01018:Vmn2r125'
ID 53543
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r125
Ensembl Gene ENSMUSG00000096042
Gene Name vomeronasal 2, receptor 125
Synonyms Gm20782
Accession Numbers
Essential gene? Probably non essential (E-score: 0.065) question?
Stock # IGL01018
Quality Score
Status
Chromosome 4
Chromosomal Location 156696567-156708037 bp(+) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) C to A at 156703194 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Glutamine to Lysine at position 191 (Q191K)
Ref Sequence ENSEMBL: ENSMUSP00000094556 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000096794]
AlphaFold no structure available at present
Predicted Effect probably benign
Transcript: ENSMUST00000096794
AA Change: Q191K

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000094556
Gene: ENSMUSG00000096042
AA Change: Q191K

DomainStartEndE-ValueType
Pfam:ANF_receptor 9 355 7e-32 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
5530400C23Rik G T 6: 133,271,460 (GRCm39) R168I probably benign Het
5530400C23Rik A T 6: 133,271,461 (GRCm39) R168S probably benign Het
Armt1 T A 10: 4,400,732 (GRCm39) S160T probably benign Het
Armt1 C T 10: 4,404,237 (GRCm39) probably benign Het
Ccdc170 T C 10: 4,462,788 (GRCm39) W35R probably benign Het
Ccdc170 T C 10: 4,464,114 (GRCm39) V31A probably benign Het
Ccdc170 G T 10: 4,464,155 (GRCm39) A99S probably benign Het
Glp2r C A 11: 67,600,470 (GRCm39) V460F probably benign Het
Gm21411 C T 4: 146,977,067 (GRCm39) S69N possibly damaging Het
Gm21411 T C 4: 146,977,034 (GRCm39) Q80R probably benign Het
Gm21738 G A 14: 19,418,856 (GRCm38) P24L probably benign Het
H2-M10.6 C T 17: 37,123,112 (GRCm39) A15V probably benign Het
H60c T C 10: 3,209,766 (GRCm39) M174V probably benign Het
H60c A C 10: 3,210,343 (GRCm39) F69V probably benign Het
Ipcef1 C T 10: 6,869,968 (GRCm39) R144Q probably damaging Het
Ipcef1 G A 10: 6,840,551 (GRCm39) A382V probably benign Het
Mapk8ip3 T G 17: 25,118,693 (GRCm39) probably benign Het
Mthfd1l T C 10: 3,928,708 (GRCm39) V100A probably benign Het
Mthfd1l T C 10: 3,957,800 (GRCm39) V279A probably benign Het
Mthfd1l T C 10: 3,982,345 (GRCm39) probably benign Het
Mtrf1l A G 10: 5,764,180 (GRCm39) probably benign Het
Myo18b T C 5: 112,957,613 (GRCm39) E1450G probably damaging Het
Obscn C T 11: 59,018,895 (GRCm39) V973M probably damaging Het
Oprm1 T C 10: 6,987,170 (GRCm39) probably benign Het
Or6p1 G A 1: 174,258,908 (GRCm39) V305I probably benign Het
Pou5f2 A G 13: 78,174,057 (GRCm39) probably benign Het
Ralgapa2 G A 2: 146,252,113 (GRCm39) H891Y probably benign Het
Ralgapa2 T G 2: 146,252,112 (GRCm39) H806P probably benign Het
Rmnd1 A G 10: 4,377,392 (GRCm39) W96R probably benign Het
Rmnd1 A T 10: 4,377,290 (GRCm39) S130T probably benign Het
Spata31e2 T C 1: 26,721,991 (GRCm39) E1063G probably damaging Het
Speer4a3 G T 5: 26,155,721 (GRCm39) H208N probably benign Het
Trappc12 A C 12: 28,741,853 (GRCm39) probably benign Het
Ulbp3 G A 10: 3,075,031 (GRCm39) noncoding transcript Het
Ulbp3 C T 10: 3,075,193 (GRCm39) noncoding transcript Het
Ulbp3 A G 10: 3,070,231 (GRCm39) noncoding transcript Het
Ulbp3 A G 10: 3,070,209 (GRCm39) noncoding transcript Het
Vip A G 10: 5,592,480 (GRCm39) D40G probably benign Het
Vmn2r129 T C 4: 156,687,885 (GRCm39) noncoding transcript Het
Vmn2r129 G A 4: 156,686,900 (GRCm39) noncoding transcript Het
Vmn2r129 A T 4: 156,690,441 (GRCm39) noncoding transcript Het
Vmn2r129 C A 4: 156,690,730 (GRCm39) noncoding transcript Het
Vmn2r129 T C 4: 156,686,558 (GRCm39) noncoding transcript Het
Vmn2r40 G A 7: 8,911,175 (GRCm39) S706F probably damaging Het
Zfp14 T A 7: 29,737,526 (GRCm39) R486S probably damaging Het
Other mutations in Vmn2r125
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00990:Vmn2r125 APN 4 156,703,194 (GRCm39) missense probably benign
IGL00990:Vmn2r125 APN 4 156,703,333 (GRCm39) missense probably benign 0.06
IGL00990:Vmn2r125 APN 4 156,703,332 (GRCm39) missense probably benign 0.16
IGL00990:Vmn2r125 APN 4 156,703,521 (GRCm39) missense probably benign
IGL00990:Vmn2r125 APN 4 156,703,678 (GRCm39) missense probably benign 0.00
IGL00990:Vmn2r125 APN 4 156,703,261 (GRCm39) missense probably benign 0.01
IGL00990:Vmn2r125 APN 4 156,703,195 (GRCm39) missense probably benign 0.35
IGL01018:Vmn2r125 APN 4 156,703,332 (GRCm39) missense probably benign 0.16
IGL01018:Vmn2r125 APN 4 156,703,195 (GRCm39) missense probably benign 0.35
IGL01018:Vmn2r125 APN 4 156,703,333 (GRCm39) missense probably benign 0.06
IGL01018:Vmn2r125 APN 4 156,703,140 (GRCm39) missense probably damaging 1.00
IGL01018:Vmn2r125 APN 4 156,702,907 (GRCm39) splice site probably benign
IGL01018:Vmn2r125 APN 4 156,703,521 (GRCm39) missense probably benign
IGL02644:Vmn2r125 APN 4 156,703,294 (GRCm39) missense probably benign 0.01
IGL03144:Vmn2r125 APN 4 156,702,314 (GRCm39) missense possibly damaging 0.76
BB013:Vmn2r125 UTSW 4 156,702,988 (GRCm39) missense probably damaging 1.00
FR4342:Vmn2r125 UTSW 4 156,703,260 (GRCm39) missense probably benign 0.01
R0408:Vmn2r125 UTSW 4 156,703,153 (GRCm39) missense probably damaging 0.99
R0785:Vmn2r125 UTSW 4 156,703,396 (GRCm39) missense probably benign
R1185:Vmn2r125 UTSW 4 156,703,396 (GRCm39) missense probably benign
R1185:Vmn2r125 UTSW 4 156,703,396 (GRCm39) missense probably benign
R1530:Vmn2r125 UTSW 4 156,703,447 (GRCm39) missense probably damaging 1.00
R1698:Vmn2r125 UTSW 4 156,703,333 (GRCm39) missense probably benign 0.06
R1780:Vmn2r125 UTSW 4 156,703,668 (GRCm39) missense probably damaging 1.00
R1977:Vmn2r125 UTSW 4 156,707,162 (GRCm39) splice site probably null
R2917:Vmn2r125 UTSW 4 156,703,564 (GRCm39) missense probably benign 0.01
R3428:Vmn2r125 UTSW 4 156,702,436 (GRCm39) missense probably benign 0.34
R3712:Vmn2r125 UTSW 4 156,702,419 (GRCm39) nonsense probably null
R4274:Vmn2r125 UTSW 4 156,702,382 (GRCm39) missense probably benign 0.00
R4575:Vmn2r125 UTSW 4 156,702,272 (GRCm39) missense probably null 0.30
R4707:Vmn2r125 UTSW 4 156,702,276 (GRCm39) missense probably damaging 1.00
R5229:Vmn2r125 UTSW 4 156,703,333 (GRCm39) missense probably benign 0.06
R5504:Vmn2r125 UTSW 4 156,703,456 (GRCm39) missense possibly damaging 0.81
R5587:Vmn2r125 UTSW 4 156,702,433 (GRCm39) missense probably damaging 1.00
R5987:Vmn2r125 UTSW 4 156,702,292 (GRCm39) missense probably damaging 1.00
R6037:Vmn2r125 UTSW 4 156,703,396 (GRCm39) missense probably benign
R6183:Vmn2r125 UTSW 4 156,702,364 (GRCm39) missense probably damaging 0.97
R6456:Vmn2r125 UTSW 4 156,703,357 (GRCm39) missense probably benign 0.41
R7342:Vmn2r125 UTSW 4 156,703,138 (GRCm39) missense probably damaging 1.00
R7926:Vmn2r125 UTSW 4 156,702,988 (GRCm39) missense probably damaging 1.00
R8113:Vmn2r125 UTSW 4 156,703,642 (GRCm39) missense probably damaging 1.00
R8191:Vmn2r125 UTSW 4 156,703,709 (GRCm39) missense probably damaging 1.00
R8272:Vmn2r125 UTSW 4 156,702,373 (GRCm39) missense probably damaging 1.00
R8962:Vmn2r125 UTSW 4 156,703,186 (GRCm39) missense possibly damaging 0.50
R9187:Vmn2r125 UTSW 4 156,703,554 (GRCm39) missense probably damaging 1.00
Posted On 2013-06-28