Mutagenetix > Incidental Mutation

Incidental Mutation 'Z1187:Myo18a'

665726

Institutional Source

Beutler Lab

Gene Symbol

Myo18a

Ensembl Gene

ENSMUSG00000000631

Gene Name

myosin XVIIIA

Synonyms

MyoPDZ

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

Z1187 ()

Quality Score

97.0078

Status

Not validated

Chromosome

Chromosomal Location

77654072-77756806 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 77744643 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Leucine at position 1970 (F1970L)

Ref Sequence

ENSEMBL: ENSMUSP00000130696 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000000645] [ENSMUST00000092884] [ENSMUST00000092887] [ENSMUST00000100794] [ENSMUST00000102488] [ENSMUST00000108375] [ENSMUST00000108376] [ENSMUST00000168348] [ENSMUST00000130305] [ENSMUST00000130627] [ENSMUST00000164334] [ENSMUST00000167856] [ENSMUST00000169105] [ENSMUST00000172303]

AlphaFold

Q9JMH9

Predicted Effect

possibly damaging
Transcript: ENSMUST00000000645
AA Change: F1923L

PolyPhen 2 Score 0.953 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000000645
Gene: ENSMUSG00000000631
AA Change: F1923L

Domain	Start	End	E-Value	Type
low complexity region	6	27	N/A	INTRINSIC
low complexity region	202	227	N/A	INTRINSIC
PDZ	229	311	5.72e-10	SMART
MYSc	399	1183	1.53e-45	SMART
IQ	1184	1206	1.11e-3	SMART
Pfam:Myosin_tail_1	1219	1867	1.7e-34	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000092884
AA Change: F1591L

PolyPhen 2 Score 0.095 (Sensitivity: 0.93; Specificity: 0.85)

SMART Domains

Protein: ENSMUSP00000090560
Gene: ENSMUSG00000000631
AA Change: F1591L

Domain	Start	End	E-Value	Type
MYSc	68	851	4.16e-47	SMART
IQ	852	874	1.11e-3	SMART
Pfam:Myosin_tail_1	888	1534	2e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000092887
AA Change: F1922L

PolyPhen 2 Score 0.972 (Sensitivity: 0.77; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000090563
Gene: ENSMUSG00000000631
AA Change: F1922L

Domain	Start	End	E-Value	Type
low complexity region	6	27	N/A	INTRINSIC
low complexity region	202	227	N/A	INTRINSIC
PDZ	229	311	5.72e-10	SMART
MYSc	399	1182	4.16e-47	SMART
IQ	1183	1205	1.11e-3	SMART
Pfam:Myosin_tail_1	1218	1866	3e-34	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000100794
AA Change: F1587L

PolyPhen 2 Score 0.880 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000098358
Gene: ENSMUSG00000000631
AA Change: F1587L

Domain	Start	End	E-Value	Type
MYSc	68	847	1.45e-46	SMART
IQ	848	870	1.11e-3	SMART
Pfam:Myosin_tail_1	884	1530	4.9e-35	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000102488
AA Change: F1922L

PolyPhen 2 Score 0.972 (Sensitivity: 0.77; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000099546
Gene: ENSMUSG00000000631
AA Change: F1922L

Domain	Start	End	E-Value	Type
low complexity region	6	27	N/A	INTRINSIC
low complexity region	202	227	N/A	INTRINSIC
PDZ	229	311	5.72e-10	SMART
MYSc	399	1182	4.16e-47	SMART
IQ	1183	1205	1.11e-3	SMART
Pfam:Myosin_tail_1	1218	1866	3e-34	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000108375
AA Change: F1922L

PolyPhen 2 Score 0.918 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000104012
Gene: ENSMUSG00000000631
AA Change: F1922L

Domain	Start	End	E-Value	Type
low complexity region	6	27	N/A	INTRINSIC
low complexity region	202	227	N/A	INTRINSIC
PDZ	229	311	5.72e-10	SMART
MYSc	399	1182	4.16e-47	SMART
IQ	1183	1205	1.11e-3	SMART
Pfam:Myosin_tail_1	1218	1838	6.8e-36	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000108376
AA Change: F1885L

PolyPhen 2 Score 0.958 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000104013
Gene: ENSMUSG00000000631
AA Change: F1885L

Domain	Start	End	E-Value	Type
low complexity region	6	27	N/A	INTRINSIC
low complexity region	202	227	N/A	INTRINSIC
PDZ	229	311	5.72e-10	SMART
MYSc	399	1182	4.16e-47	SMART
IQ	1183	1205	1.11e-3	SMART
Blast:MYSc	1258	1387	1e-14	BLAST
low complexity region	1396	1407	N/A	INTRINSIC
low complexity region	1743	1762	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000168348
AA Change: F1970L

PolyPhen 2 Score 0.954 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000130696
Gene: ENSMUSG00000000631
AA Change: F1970L

Domain	Start	End	E-Value	Type
low complexity region	6	27	N/A	INTRINSIC
low complexity region	202	227	N/A	INTRINSIC
PDZ	229	311	5.72e-10	SMART
MYSc	447	1230	4.16e-47	SMART
IQ	1231	1253	1.11e-3	SMART
Blast:MYSc	1306	1435	1e-14	BLAST
low complexity region	1444	1455	N/A	INTRINSIC
low complexity region	1828	1847	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000130305
AA Change: F1603L

PolyPhen 2 Score 0.927 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000119574
Gene: ENSMUSG00000000631
AA Change: F1603L

Domain	Start	End	E-Value	Type
MYSc	80	863	4.16e-47	SMART
IQ	864	886	1.11e-3	SMART
Pfam:Myosin_tail_1	902	1547	2.6e-34	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000130627
AA Change: F1934L

PolyPhen 2 Score 0.951 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000119839
Gene: ENSMUSG00000000631
AA Change: F1934L

Domain	Start	End	E-Value	Type
low complexity region	6	27	N/A	INTRINSIC
low complexity region	202	227	N/A	INTRINSIC
PDZ	229	311	5.72e-10	SMART
MYSc	411	1194	4.16e-47	SMART
IQ	1195	1217	1.11e-3	SMART
Pfam:Myosin_tail_1	1230	1850	6.9e-36	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000135375

SMART Domains

Protein: ENSMUSP00000117044
Gene: ENSMUSG00000000631

Domain	Start	End	E-Value	Type
low complexity region	198	231	N/A	INTRINSIC
low complexity region	289	303	N/A	INTRINSIC
low complexity region	361	459	N/A	INTRINSIC
low complexity region	474	486	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000164334
AA Change: F1591L

PolyPhen 2 Score 0.951 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000131771
Gene: ENSMUSG00000000631
AA Change: F1591L

Domain	Start	End	E-Value	Type
MYSc	68	851	4.16e-47	SMART
IQ	852	874	1.11e-3	SMART
Pfam:Myosin_tail_1	888	1505	4e-36	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000167856
AA Change: F1529L

PolyPhen 2 Score 0.801 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000128487
Gene: ENSMUSG00000000631
AA Change: F1529L

Domain	Start	End	E-Value	Type
MYSc	16	789	1.3e-32	SMART
IQ	790	812	1.11e-3	SMART
Blast:MYSc	865	994	1e-14	BLAST
low complexity region	1003	1014	N/A	INTRINSIC
low complexity region	1387	1406	N/A	INTRINSIC
internal_repeat_1	1569	1627	2.13e-5	PROSPERO

Predicted Effect

possibly damaging
Transcript: ENSMUST00000169105
AA Change: F1934L

PolyPhen 2 Score 0.918 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000132149
Gene: ENSMUSG00000000631
AA Change: F1934L

Domain	Start	End	E-Value	Type
low complexity region	6	27	N/A	INTRINSIC
low complexity region	202	227	N/A	INTRINSIC
PDZ	229	311	5.72e-10	SMART
MYSc	411	1194	4.16e-47	SMART
IQ	1195	1217	1.11e-3	SMART
Pfam:Myosin_tail_1	1230	1878	7.3e-35	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000172303
AA Change: F1609L

PolyPhen 2 Score 0.918 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000129098
Gene: ENSMUSG00000000631
AA Change: F1609L

Domain	Start	End	E-Value	Type
MYSc	80	863	4.16e-47	SMART
IQ	864	886	1.11e-3	SMART
Pfam:Myosin_tail_1	902	1547	2.6e-34	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.4%
20x: 98.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016]

Allele List at MGI

Other mutations in this stock

Total: 419 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700086D15Rik	A	G	11: 65,044,114 (GRCm39)	W27R	unknown	Het
1700086D15Rik	A	G	11: 65,044,080 (GRCm39)	F38S	unknown	Het
1700086D15Rik	A	C	11: 65,043,809 (GRCm39)	V84G	unknown	Het
1700086D15Rik	T	A	11: 65,043,794 (GRCm39)	Q89L	unknown	Het
1700086D15Rik	A	G	11: 65,044,128 (GRCm39)	L22P	unknown	Het
1810065E05Rik	C	T	11: 58,313,027 (GRCm39)	L27F	probably benign	Het
1810065E05Rik	C	T	11: 58,316,625 (GRCm39)	L202F	probably benign	Het
1810065E05Rik	C	T	11: 58,313,060 (GRCm39)	L38F	possibly damaging	Het
2810021J22Rik	C	T	11: 58,771,361 (GRCm39)	A281V	probably benign	Het
4930438A08Rik	A	G	11: 58,184,844 (GRCm39)	T521A	unknown	Het
4933427D14Rik	G	A	11: 72,067,535 (GRCm39)	T585I	possibly damaging	Het
4933427D14Rik	T	G	11: 72,089,750 (GRCm39)	S45R	probably damaging	Het
4933427D14Rik	C	A	11: 72,089,360 (GRCm39)	A175S	probably benign	Het
4933427D14Rik	G	A	11: 72,089,308 (GRCm39)	P192L	probably benign	Het
4933427D14Rik	T	TCCCCAGC	11: 72,086,590 (GRCm39)		probably null	Het
4933427D14Rik	T	G	11: 72,086,580 (GRCm39)	K277T	probably damaging	Het
4933427D14Rik	A	G	11: 72,086,569 (GRCm39)	C281R	possibly damaging	Het
4933427D14Rik	AAAAGTAA	AAA	11: 72,086,538 (GRCm39)		probably null	Het
4933427D14Rik	GGAAAAG	GG	11: 72,086,536 (GRCm39)		probably null	Het
4933427D14Rik	G	T	11: 72,080,442 (GRCm39)	P408H	probably damaging	Het
Adgra3	G	A	5: 50,136,421 (GRCm39)	A688V	probably damaging	Het
Adh1	T	C	3: 137,992,544 (GRCm39)	I220T	probably damaging	Het
Adh4	T	C	3: 138,125,091 (GRCm39)		probably null	Het
Akap10	T	A	11: 61,806,096 (GRCm39)	S211C	probably benign	Het
Alg10b	C	A	15: 90,112,397 (GRCm39)	L414I	possibly damaging	Het
Alox8	C	T	11: 69,076,873 (GRCm39)	R536Q	probably benign	Het
Alox8	A	G	11: 69,088,322 (GRCm39)	V76A	probably benign	Het
Aloxe3	A	G	11: 69,019,501 (GRCm39)	Q138R	probably benign	Het
Aloxe3	C	T	11: 69,039,429 (GRCm39)	A667V	probably benign	Het
Ank2	A	G	3: 126,749,601 (GRCm39)	F476S	probably damaging	Het
Aplp2	T	A	9: 31,063,637 (GRCm39)	E657V	possibly damaging	Het
Aspa	G	T	11: 73,213,013 (GRCm39)	L110I	probably benign	Het
Atp6v1g3	A	G	1: 138,201,582 (GRCm39)	K27E	possibly damaging	Het
Aurkb	T	C	11: 68,938,696 (GRCm39)	F45S	probably benign	Het
Aurkb	C	T	11: 68,938,692 (GRCm39)	R44W	probably damaging	Het
B9d1	A	T	11: 61,396,029 (GRCm39)		probably benign	Het
BC034090	A	G	1: 155,117,245 (GRCm39)	I291T	probably benign	Het
Borcs6	G	A	11: 68,951,453 (GRCm39)	R277Q	possibly damaging	Het
Btnl10	T	C	11: 58,810,138 (GRCm39)	V93A	probably benign	Het
Btnl10	C	T	11: 58,817,650 (GRCm39)	T250I	unknown	Het
Btnl10	AGAC	AGACGAC	11: 58,814,755 (GRCm39)		probably benign	Het
Btnl10	AAAGA	AAAGAAGA	11: 58,814,753 (GRCm39)		probably benign	Het
Ccdc42	C	T	11: 68,478,017 (GRCm39)		probably benign	Het
Ccdc92b	A	G	11: 74,520,880 (GRCm39)	M61V	possibly damaging	Het
Chd3	C	A	11: 69,239,271 (GRCm39)	E1753D	probably benign	Het
Chd3	A	G	11: 69,252,277 (GRCm39)	W42R	probably benign	Het
Chrna9	T	C	5: 66,134,123 (GRCm39)	F325L	probably benign	Het
Clec3a	G	A	8: 115,144,859 (GRCm39)	V12M	possibly damaging	Het
Cluh	CCCCGAGCC	CCCCGAGCCCGAGCC	11: 74,560,340 (GRCm39)		probably benign	Het
Cluh	TGAGCC	TGAGCCCGAGCC	11: 74,560,355 (GRCm39)		probably benign	Het
Cluh	G	GGGCCTA	11: 74,560,350 (GRCm39)		probably benign	Het
Cluh	CCTGAG	CCTGAGTCTGAG	11: 74,560,347 (GRCm39)		probably benign	Het
Cluh	GCCTGA	GCCTGATCCTGA	11: 74,560,346 (GRCm39)		probably benign	Het
Cluh	CGAGCCTGAGCCTGAGCC	CGAGCCTGAGCCTGAGCCTGAGCC	11: 74,560,343 (GRCm39)		probably benign	Het
Cluh	CCGAGCC	CCGAGCCCGAGCC	11: 74,560,342 (GRCm39)		probably benign	Het
Cnot9	T	A	1: 74,556,285 (GRCm39)	N27K	probably benign	Het
Cntrob	G	A	11: 69,198,882 (GRCm39)	P622L	probably benign	Het
Cntrob	C	T	11: 69,196,404 (GRCm39)	R677H	probably benign	Het
Crybg3	C	T	16: 59,326,608 (GRCm39)	V1041M	probably damaging	Het
Cyb5d1	C	A	11: 69,286,098 (GRCm39)	A8S	probably benign	Het
Cyb5d1	A	G	11: 69,286,028 (GRCm39)	L31P	probably benign	Het
Dnah9	A	C	11: 65,976,000 (GRCm39)	S1350A	probably benign	Het
Dnah9	G	A	11: 66,038,207 (GRCm39)	H110Y	probably benign	Het
Eif2b5	C	T	16: 20,317,671 (GRCm39)	A3V	unknown	Het
Elac2	T	C	11: 64,870,015 (GRCm39)	S27P	probably benign	Het
Epn2	C	A	11: 61,470,460 (GRCm39)		probably benign	Het
Fam114a2	T	C	11: 57,390,623 (GRCm39)	N304D	probably benign	Het
Fam114a2	C	T	11: 57,405,060 (GRCm39)	G14E	probably benign	Het
Fam114a2	A	G	11: 57,374,858 (GRCm39)	S494P	probably benign	Het
Fam114a2	G	A	11: 57,380,940 (GRCm39)	A438V	probably benign	Het
Fam114a2	C	T	11: 57,390,581 (GRCm39)	V318I	probably benign	Het
Fam83g	G	A	11: 61,594,020 (GRCm39)	R518Q	probably benign	Het
Fat2	T	G	11: 55,200,625 (GRCm39)	K816N	probably benign	Het
Fat2	TGTACCTCACCCCAGTACCT	TGTACCT	11: 55,199,796 (GRCm39)		probably null	Het
Fbxw10	G	C	11: 62,738,118 (GRCm39)	R4T	probably benign	Het
Fbxw10	G	A	11: 62,767,671 (GRCm39)	V836I	probably benign	Het
Foxo6	C	T	4: 120,144,332 (GRCm39)	G40R	possibly damaging	Het
Fsd1	C	A	17: 56,300,920 (GRCm39)	P260T	probably benign	Het
Galnt10	G	A	11: 57,656,514 (GRCm39)	V233I	probably benign	Het
Gemin5	T	C	11: 58,016,044 (GRCm39)	S1321G	probably benign	Het
Gemin5	T	C	11: 58,020,897 (GRCm39)	M1097V	probably benign	Het
Gemin5	C	G	11: 58,030,336 (GRCm39)	A830P	probably benign	Het
Gemin5	C	G	11: 58,030,401 (GRCm39)	C808S	probably benign	Het
Gemin5	C	G	11: 58,037,345 (GRCm39)	E623D	probably benign	Het
Gemin5	C	G	11: 58,013,115 (GRCm39)	S1446T	probably benign	Het
Ggnbp2	C	T	11: 84,727,478 (GRCm39)	R481Q	probably benign	Het
Gjc2	T	C	11: 59,067,259 (GRCm39)	S408G	unknown	Het
Gjc2	ACCCTCCCT	ACCCTCCCTCCCT	11: 59,073,561 (GRCm39)		probably benign	Het
Glod4	T	C	11: 76,134,430 (GRCm39)	K14R	probably benign	Het
Glod4	T	C	11: 76,134,431 (GRCm39)	K14E	probably benign	Het
Glod4	C	A	11: 76,133,819 (GRCm39)		probably null	Het
Glod4	A	G	11: 76,133,836 (GRCm39)	V6A	probably benign	Het
Glp2r	C	G	11: 67,600,472 (GRCm39)	G459A	probably benign	Het
Glp2r	C	T	11: 67,630,993 (GRCm39)	V295I	probably benign	Het
Glp2r	A	G	11: 67,631,878 (GRCm39)	V283A	probably benign	Het
Glp2r	T	C	11: 67,631,885 (GRCm39)	I281V	probably benign	Het
Glp2r	T	C	11: 67,633,129 (GRCm39)	T235A	probably benign	Het
Glp2r	A	G	11: 67,635,773 (GRCm39)	V189A	probably benign	Het
Glp2r	C	A	11: 67,661,662 (GRCm39)	A13S	probably benign	Het
Glp2r	C	A	11: 67,600,394 (GRCm39)	R485L	probably damaging	Het
Glp2r	C	A	11: 67,600,470 (GRCm39)	V460F	probably benign	Het
Gm12253	A	C	11: 58,325,686 (GRCm39)	E52D	probably benign	Het
Gm12253	A	G	11: 58,325,658 (GRCm39)	E43G	probably benign	Het
Gm12253	G	C	11: 58,325,367 (GRCm39)	S13T	possibly damaging	Het
Gm12253	G	A	11: 58,331,835 (GRCm39)	A215T	possibly damaging	Het
Gm12253	G	A	11: 58,326,309 (GRCm39)	S108N	probably benign	Het
Gm12253	A	C	11: 58,326,237 (GRCm39)	E84A	probably benign	Het
Gm12258	T	G	11: 58,749,126 (GRCm39)	S100R		Het
Gm12258	C	T	11: 58,749,262 (GRCm39)	R146W		Het
Gm12258	G	C	11: 58,750,690 (GRCm39)	G622R	unknown	Het
Gm12258	T	A	11: 58,750,014 (GRCm39)		probably benign	Het
Gm12258	A	G	11: 58,750,013 (GRCm39)		probably benign	Het
Gm12258	A	T	11: 58,749,833 (GRCm39)	E336V	unknown	Het
Gm12258	G	A	11: 58,749,776 (GRCm39)	G317E	unknown	Het
Gm12258	G	A	11: 58,749,764 (GRCm39)	R313H	unknown	Het
Golga5	A	G	12: 102,440,853 (GRCm39)	E196G	probably benign	Het
Gps2	C	T	11: 69,807,130 (GRCm39)	A60V	probably benign	Het
Gucy2e	C	G	11: 69,127,429 (GRCm39)	G15R	unknown	Het
Gucy2e	C	A	11: 69,114,431 (GRCm39)	A1033S	probably benign	Het
Guk1	G	A	11: 59,082,747 (GRCm39)		probably benign	Het
Haspin	T	C	11: 73,028,174 (GRCm39)	Q305R	probably benign	Het
Haspin	A	G	11: 73,028,777 (GRCm39)	L104P	probably benign	Het
Hes7	T	C	11: 69,013,782 (GRCm39)	S214P	probably benign	Het
Hic1	G	A	11: 75,058,352 (GRCm39)	T179M	probably damaging	Het
Iba57	AG	AGCG	11: 59,052,330 (GRCm39)		probably null	Het
Iba57	CAGA	CAGAGA	11: 59,052,329 (GRCm39)		probably null	Het
Iba57	C	G	11: 59,053,865 (GRCm39)	G36R	unknown	Het
Iba57	T	C	11: 59,052,384 (GRCm39)	T86A	unknown	Het
Iba57	T	C	11: 59,052,381 (GRCm39)	T87A	unknown	Het
Ifi207	G	A	1: 173,558,093 (GRCm39)	T215I	unknown	Het
Iftap	T	C	2: 101,440,950 (GRCm39)	K18E	probably benign	Het
Igtp	C	G	11: 58,097,791 (GRCm39)	L321V	possibly damaging	Het
Igtp	T	G	11: 58,097,169 (GRCm39)	D113E	probably damaging	Het
Igtp	C	G	11: 58,097,944 (GRCm39)	L372V	probably benign	Het
Irgm2	A	C	11: 58,110,951 (GRCm39)	H214P	probably benign	Het
Irgm2	G	A	11: 58,110,924 (GRCm39)	S205N	probably benign	Het
Irgm2	G	A	11: 58,110,833 (GRCm39)	V175I	probably benign	Het
Irgm2	A	G	11: 58,110,389 (GRCm39)	N27D	probably benign	Het
Irgm2	G	T	11: 58,111,238 (GRCm39)	A310S	possibly damaging	Het
Irgm2	C	G	11: 58,111,389 (GRCm39)	T360S	probably benign	Het
Irgm2	T	A	11: 58,110,339 (GRCm39)	V10D	probably benign	Het
Irgm2	T	C	11: 58,110,780 (GRCm39)	L157S	probably benign	Het
Irgm2	T	C	11: 58,110,738 (GRCm39)	I143T	probably benign	Het
Itgae	T	A	11: 72,994,713 (GRCm39)	L22M	possibly damaging	Het
Itgae	A	T	11: 72,994,786 (GRCm39)	Q46L	probably damaging	Het
Itgae	A	G	11: 73,006,466 (GRCm39)	H378R	probably benign	Het
Itgae	G	A	11: 73,008,913 (GRCm39)	V465I	probably benign	Het
Itgae	A	T	11: 73,012,757 (GRCm39)	K696N	probably benign	Het
Itgae	G	T	11: 73,012,783 (GRCm39)	G705V	probably benign	Het
Itgae	C	G	11: 73,024,953 (GRCm39)	S1028W	probably benign	Het
Kif1c	C	T	11: 70,614,940 (GRCm39)	P578L	probably benign	Het
Klhdc7a	A	G	4: 139,693,852 (GRCm39)	I365T	probably damaging	Het
Kmt2d	T	C	15: 98,749,625 (GRCm39)	N2656D	unknown	Het
Larp1	G	A	11: 57,933,166 (GRCm39)	V257I	probably benign	Het
Llgl1	ACCCCAGCCCTTCTGATTACTGCCCTCCCCAGC	ACCCCAGC	11: 60,603,923 (GRCm39)		probably null	Het
Lrp1b	A	T	2: 40,640,946 (GRCm39)	N3499K		Het
Lypd8	C	A	11: 58,275,475 (GRCm39)	A70E	possibly damaging	Het
Lypd8	G	A	11: 58,275,489 (GRCm39)	E75K	probably benign	Het
Lypd8	CAATCACCAACA	CAATCACCAACAGTTCCCTCGCCTCTGTTACCCCACAAATCACCAACA	11: 58,281,059 (GRCm39)		probably benign	Het
Lypd8	T	C	11: 58,273,601 (GRCm39)	Y27H	probably benign	Het
Lypd8l	A	G	11: 58,503,387 (GRCm39)	L47P	probably benign	Het
Lypd8l	G	A	11: 58,499,335 (GRCm39)	P161L	probably benign	Het
Lypd8l	T	G	11: 58,503,397 (GRCm39)	S44R	probably benign	Het
Mapk7	CGCTGGTGCTGG	CGCTGGTGCTGGTGCTGG	11: 61,381,038 (GRCm39)		probably benign	Het
Mapk7	TGGGGCAGGGGCAGGGGCAGG	TGGCGCTGGGGCAGGGGCAGGGGCAGGGGCAGG	11: 61,381,053 (GRCm39)		probably benign	Het
Mfap3	A	T	11: 57,418,866 (GRCm39)	I9F	possibly damaging	Het
Mfap3	G	A	11: 57,418,902 (GRCm39)	G21S	probably benign	Het
Mrm3	G	A	11: 76,134,903 (GRCm39)	R102K	probably benign	Het
Mrm3	C	T	11: 76,138,221 (GRCm39)	P203L	probably benign	Het
Mrpl22	G	A	11: 58,062,521 (GRCm39)	A4T	unknown	Het
Mrpl55	A	G	11: 59,094,999 (GRCm39)		probably null	Het
Mrpl55	A	T	11: 59,095,415 (GRCm39)	L26F	probably benign	Het
Myh1	A	C	11: 67,095,272 (GRCm39)	T211P	probably benign	Het
Myh8	A	C	11: 67,188,312 (GRCm39)	N991T	probably benign	Het
Myocd	A	G	11: 65,075,418 (GRCm39)	S697P	probably benign	Het
Nlgn2	A	G	11: 69,719,220 (GRCm39)	V210A	possibly damaging	Het
Nlrp1a	T	C	11: 71,014,914 (GRCm39)	E112G	probably benign	Het
Nlrp1a	T	C	11: 70,990,442 (GRCm39)	I1038V	probably benign	Het
Nlrp1a	C	T	11: 70,988,077 (GRCm39)	R1131Q	probably damaging	Het
Nlrp1a	T	C	11: 70,983,069 (GRCm39)	K1299R	probably benign	Het
Nlrp1a	C	G	11: 71,033,355 (GRCm39)		probably null	Het
Nlrp1b	A	C	11: 71,072,539 (GRCm39)	S435A	probably benign	Het
Nlrp1b	C	A	11: 71,072,534 (GRCm39)	M436I	probably benign	Het
Nlrp1b	T	C	11: 71,073,503 (GRCm39)	I113M	probably benign	Het
Nlrp1b	T	A	11: 71,073,396 (GRCm39)	Q149L	probably benign	Het
Nlrp1b	A	T	11: 71,073,378 (GRCm39)	M155K	probably benign	Het
Nlrp1b	C	G	11: 71,073,370 (GRCm39)	E158Q	probably benign	Het
Nlrp1b	T	C	11: 71,073,280 (GRCm39)	T188A	probably benign	Het
Nlrp1b	A	T	11: 71,073,266 (GRCm39)	D192E	probably benign	Het
Nlrp1b	A	G	11: 71,073,148 (GRCm39)	Y232H	probably benign	Het
Nlrp1b	A	G	11: 71,072,625 (GRCm39)	I406T	probably benign	Het
Nmur2	T	C	11: 55,931,104 (GRCm39)	I202M	probably benign	Het
Obscn	G	T	11: 58,984,334 (GRCm39)	A1707D	possibly damaging	Het
Obscn	C	T	11: 58,984,335 (GRCm39)	A1707T	probably benign	Het
Obscn	G	A	11: 58,984,385 (GRCm39)	A1690V	probably benign	Het
Obscn	C	T	11: 58,990,735 (GRCm39)	A1613T	possibly damaging	Het
Obscn	T	C	11: 58,990,755 (GRCm39)	H1606R	probably benign	Het
Obscn	C	G	11: 58,994,167 (GRCm39)	A1572P	probably damaging	Het
Obscn	T	C	11: 58,994,340 (GRCm39)	H1514R	probably benign	Het
Obscn	G	A	11: 58,994,364 (GRCm39)	A1506V	probably benign	Het
Obscn	T	C	11: 59,003,380 (GRCm39)	E1306G	probably benign	Het
Obscn	T	C	11: 59,013,563 (GRCm39)	M1095V	probably benign	Het
Obscn	C	T	11: 59,018,892 (GRCm39)	A949T	probably benign	Het
Obscn	C	T	11: 59,018,895 (GRCm39)	V973M	probably damaging	Het
Obscn	G	T	11: 59,020,663 (GRCm39)	L794M	probably benign	Het
Obscn	C	T	11: 59,021,449 (GRCm39)	R797H	probably damaging	Het
Obscn	C	T	11: 59,023,937 (GRCm39)	A578T	possibly damaging	Het
Obscn	G	A	11: 59,024,066 (GRCm39)	P535S	probably damaging	Het
Obscn	C	G	11: 59,024,072 (GRCm39)	A533P	probably benign	Het
Obscn	T	C	11: 59,026,505 (GRCm39)	I233V	probably benign	Het
Obscn	C	T	11: 58,940,306 (GRCm39)	D5354N		Het
Obscn	C	A	11: 58,940,614 (GRCm39)	R4593S	possibly damaging	Het
Obscn	T	C	11: 58,940,623 (GRCm39)	T5307A		Het
Obscn	G	A	11: 58,942,383 (GRCm39)	T4372M	probably benign	Het
Obscn	T	C	11: 58,943,439 (GRCm39)	M4237V	probably benign	Het
Obscn	C	T	11: 58,944,594 (GRCm39)	R4700Q	probably benign	Het
Obscn	T	C	11: 58,944,651 (GRCm39)	K4681R	probably benign	Het
Obscn	T	C	11: 58,945,044 (GRCm39)	E4658G	probably benign	Het
Obscn	C	T	11: 58,945,176 (GRCm39)	R4614Q	probably benign	Het
Obscn	T	C	11: 58,946,331 (GRCm39)	D4458G	probably damaging	Het
Obscn	C	T	11: 58,946,340 (GRCm39)	R4455K	probably benign	Het
Obscn	G	T	11: 58,946,936 (GRCm39)	A4066E	possibly damaging	Het
Obscn	A	G	11: 58,947,595 (GRCm39)	M4478T		Het
Obscn	C	A	11: 58,951,823 (GRCm39)	G3977W	probably damaging	Het
Obscn	C	T	11: 58,952,388 (GRCm39)	G3894R	probably benign	Het
Obscn	CCACACACACACAC	CCACACACACAC	11: 58,954,279 (GRCm39)		probably null	Het
Obscn	T	C	11: 58,954,300 (GRCm39)	T4037A		Het
Obscn	T	C	11: 58,954,402 (GRCm39)	K3727E	probably damaging	Het
Obscn	G	A	11: 58,957,973 (GRCm39)	R3576C	probably benign	Het
Obscn	C	T	11: 58,958,655 (GRCm39)	V3433I	probably benign	Het
Obscn	G	A,C	11: 58,960,659 (GRCm39)		silent	Het
Obscn	C	A	11: 58,960,757 (GRCm39)	A3185S	probably benign	Het
Obscn	C	T	11: 58,967,334 (GRCm39)	V2792I	possibly damaging	Het
Obscn	G	A	11: 58,891,715 (GRCm39)	A6939V	probably benign	Het
Obscn	C	G	11: 58,900,019 (GRCm39)	G938A	probably benign	Het
Obscn	G	C	11: 58,904,014 (GRCm39)	T7320S	probably benign	Het
Obscn	C	T	11: 58,921,934 (GRCm39)	R5954Q	probably damaging	Het
Obscn	G	C	11: 58,929,976 (GRCm39)	P5080A	probably benign	Het
Obscn	T	A	11: 58,929,990 (GRCm39)	Q5075L	probably damaging	Het
Obscn	T	C	11: 58,932,601 (GRCm39)	I4869V	probably benign	Het
Obscn	T	C	11: 58,933,776 (GRCm39)	T5363A	probably benign	Het
Obscn	G	A	11: 58,933,853 (GRCm39)	A5337V	probably benign	Het
Obscn	G	A	11: 58,933,878 (GRCm39)	R5329C	probably benign	Het
Obscn	G	A	11: 58,969,984 (GRCm39)	R53C	probably damaging	Het
Obscn	C	T	11: 58,984,239 (GRCm39)	V1739M	possibly damaging	Het
Obscn	A	G	11: 58,984,142 (GRCm39)	F1771S	probably benign	Het
Obscn	A	G	11: 58,977,565 (GRCm39)	V1845A	probably benign	Het
Obscn	T	C	11: 58,977,527 (GRCm39)	R1858G	probably benign	Het
Obscn	C	T	11: 58,977,505 (GRCm39)	R1865H	probably benign	Het
Obscn	C	A	11: 58,972,698 (GRCm39)	G2116V	possibly damaging	Het
Obscn	C	G	11: 58,970,722 (GRCm39)	V2328L	probably benign	Het
Or11l3	A	C	11: 58,516,732 (GRCm39)	C46G	possibly damaging	Het
Or11l3	T	G	11: 58,516,619 (GRCm39)	K84N	probably benign	Het
Or11l3	G	A	11: 58,516,588 (GRCm39)	P95S	probably benign	Het
Or11l3	C	G	11: 58,516,130 (GRCm39)	G61R	probably benign	Het
Or11l3	G	A	11: 58,516,075 (GRCm39)	S79F	probably benign	Het
Or14j10	A	G	17: 37,934,735 (GRCm39)	S264P	probably damaging	Het
Or2ab1	A	C	11: 58,488,344 (GRCm39)	I35L	probably benign	Het
Or2ab1	A	G	11: 58,488,776 (GRCm39)	S179G	probably benign	Het
Or2ab1	A	G	11: 58,488,491 (GRCm39)	S84G	possibly damaging	Het
Or2ab1	A	G	11: 58,488,356 (GRCm39)	I39V	probably benign	Het
Or2ak4	G	A	11: 58,648,793 (GRCm39)	A101T	probably benign	Het
Or2ak4	A	C	11: 58,649,186 (GRCm39)	K232Q	probably benign	Het
Or2ak4	A	C	11: 58,649,168 (GRCm39)	I226L	probably benign	Het
Or2ak4	G	A	11: 58,649,153 (GRCm39)	V221M	probably damaging	Het
Or2ak4	A	G	11: 58,648,931 (GRCm39)	S147G	probably benign	Het
Or2ak4	C	T	11: 58,648,895 (GRCm39)	L135F	probably benign	Het
Or2ak5	G	A	11: 58,611,922 (GRCm39)		probably benign	Het
Or2ak6	C	A	11: 58,593,222 (GRCm39)	Q232K	probably benign	Het
Or2ak6	C	T	11: 58,593,153 (GRCm39)	L209F	possibly damaging	Het
Or2ak6	A	C	11: 58,592,784 (GRCm39)	I86L	probably benign	Het
Or2ak7	T	C	11: 58,574,815 (GRCm39)	F39L	probably benign	Het
Or2ak7	G	T	11: 58,574,758 (GRCm39)	D20Y	probably benign	Het
Or2ak7	T	C	11: 58,575,548 (GRCm39)	L283P	probably benign	Het
Or2ak7	C	T	11: 58,575,289 (GRCm39)	H197Y	probably benign	Het
Or2ak7	G	A	11: 58,575,083 (GRCm39)	R128Q	probably benign	Het
Or2ak7	G	A	11: 58,574,941 (GRCm39)	V81M	probably benign	Het
Or2av9	C	T	11: 58,381,123 (GRCm39)	A153T	probably benign	Het
Or2av9	C	A	11: 58,380,574 (GRCm39)	E336*	probably null	Het
Or2av9	T	C	11: 58,381,314 (GRCm39)	Q89R	probably benign	Het
Or2t29	G	T	11: 58,434,272 (GRCm39)	S23Y	probably benign	Het
Or2t43	G	A	11: 58,457,388 (GRCm39)	A261V	probably benign	Het
Or2t43	C	T	11: 58,457,920 (GRCm39)	V84I	probably benign	Het
Or2t43	A	T	11: 58,457,521 (GRCm39)	S217T	probably benign	Het
Or2t44	A	G	11: 58,677,773 (GRCm39)	T238A	probably damaging	Het
Or2t46	G	A	11: 58,471,828 (GRCm39)	V53I	probably benign	Het
Or2t46	T	G	11: 58,472,122 (GRCm39)	L151V	probably benign	Het
Or2t46	G	C	11: 58,472,483 (GRCm39)	S271T	probably benign	Het
Or2t46	C	T	11: 58,471,750 (GRCm39)	H27Y	probably benign	Het
Or2t46	T	C	11: 58,471,757 (GRCm39)	V29A	probably benign	Het
Or2t47	C	T	11: 58,442,801 (GRCm39)	S88N	probably benign	Het
Or2t47	C	T	11: 58,442,940 (GRCm39)	A42T	probably benign	Het
Or2t47	T	C	11: 58,442,387 (GRCm39)	K226R	probably benign	Het
Or2t49	C	A	11: 58,392,936 (GRCm39)	V155F	probably benign	Het
Or2t49	GGTGGATTGGTATGTGGAT	GGTGGAT	11: 58,393,212 (GRCm39)		probably benign	Het
Or2t49	C	G	11: 58,393,287 (GRCm39)	V38L	probably benign	Het
Or2t49	C	T	11: 58,393,396 (GRCm39)	M1I	probably null	Het
Or2t49	T	C	11: 58,392,474 (GRCm39)	M309V	probably benign	Het
Or2t49	T	C	11: 58,392,927 (GRCm39)	I158V	probably benign	Het
Or2w3	T	G	11: 58,557,342 (GRCm39)	I319R	probably benign	Het
Or2w3b	C	A	11: 58,624,048 (GRCm39)		probably benign	Het
Or2w3b	T	G	11: 58,623,200 (GRCm39)	N264H	probably benign	Het
Or2w3b	T	C	11: 58,623,475 (GRCm39)	H172R	probably benign	Het
Or2w3b	G	A	11: 58,623,295 (GRCm39)	A232V	probably benign	Het
Or5af2	T	C	11: 58,708,122 (GRCm39)	V96A	probably benign	Het
Or5af2	A	G	11: 58,707,887 (GRCm39)	I18V	probably benign	Het
Or5af2	C	G	11: 58,708,644 (GRCm39)	P270R	probably benign	Het
Or5af2	T	C	11: 58,708,508 (GRCm39)	C225R	probably benign	Het
Or5af2	C	G	11: 58,708,243 (GRCm39)	H136Q	probably benign	Het
Or5af2	A	C	11: 58,708,220 (GRCm39)	I129L	probably benign	Het
Or6k2	C	A	1: 173,986,907 (GRCm39)	C189*	probably null	Het
Or9e1	G	T	11: 58,731,945 (GRCm39)	A2S	probably benign	Het
Or9e1	G	C	11: 58,731,907 (GRCm39)		probably benign	Het
Or9e1	A	G	11: 58,732,615 (GRCm39)	H225R	probably benign	Het
Or9e1	G	A	11: 58,732,569 (GRCm39)	A210T	probably benign	Het
Or9e1	C	T	11: 58,732,032 (GRCm39)	L31F	probably benign	Het
Or9e1	T	C	11: 58,732,084 (GRCm39)	I48T	probably benign	Het
Otx1	C	A	11: 21,947,037 (GRCm39)	A91S	probably damaging	Het
Ovca2	T	C	11: 75,069,528 (GRCm39)	T32A	probably benign	Het
Pfkfb1	T	G	X: 149,391,627 (GRCm39)	V25G	probably damaging	Het
Pimreg	G	A	11: 71,935,979 (GRCm39)	R154H	probably damaging	Het
Pimreg	TCACA	TCA	11: 71,935,801 (GRCm39)		probably benign	Het
Pitpnm3	C	T	11: 72,010,969 (GRCm39)	R21Q	probably benign	Het
Pitpnm3	T	C	11: 71,954,955 (GRCm39)	K520E	probably benign	Het
Ppp1r12b	C	G	1: 134,883,262 (GRCm39)	V87L	probably benign	Het
Pramel13	A	G	4: 144,122,517 (GRCm39)	L9P	probably damaging	Het
Prpsap2	A	C	11: 61,647,078 (GRCm39)	V21G	possibly damaging	Het
Rabep1	C	CT	11: 70,830,910 (GRCm39)		probably null	Het
Rai1	A	G	11: 60,078,389 (GRCm39)	N818D	probably benign	Het
Rap1gap2	C	T	11: 74,487,721 (GRCm39)	E52K	probably benign	Het
Rc3h2	T	C	2: 37,289,612 (GRCm39)	H400R	possibly damaging	Het
Rnf112	A	G	11: 61,341,775 (GRCm39)	L343P	unknown	Het
Rnf167	C	CACAGGGA	11: 70,541,646 (GRCm39)		probably null	Het
Rtn4rl1	C	T	11: 75,156,863 (GRCm39)	P432S	probably benign	Het
Shisa6	CGCCGC	CGCCGCAGCCGC	11: 66,416,533 (GRCm39)		probably benign	Het
Shisa6	CGCCGC	CGCCGCGGCCGC	11: 66,416,524 (GRCm39)		probably benign	Het
Slc2a4	GCC	G	11: 69,834,819 (GRCm39)		probably null	Het
Slc2a4	GGCCG	GG	11: 69,834,818 (GRCm39)		probably benign	Het
Slc6a4	A	G	11: 76,903,858 (GRCm39)	K152R	probably benign	Het
Slc6a4	G	A	11: 76,901,382 (GRCm39)	G39E	probably benign	Het
Smcr8	T	C	11: 60,669,932 (GRCm39)	V360A	probably benign	Het
Smcr8	A	G	11: 60,668,806 (GRCm39)		probably benign	Het
Smcr8	C	A	11: 60,670,699 (GRCm39)	R616S	probably benign	Het
Smg6	G	T	11: 75,047,092 (GRCm39)	A1262S	probably benign	Het
Spata31h1	CGAATCTGCACACTGAGGACTTGGCCCTGGGATGCATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGGATGCATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGGATGCATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGGATGTATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGG	CGAATCTGCACACTGAGGACTTGGCCCTGGGATGCATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGGATGCATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGGATGTATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGG	10: 82,124,390 (GRCm39)		probably benign	Het
Spns3	T	C	11: 72,440,863 (GRCm39)	I58V	probably benign	Het
Spns3	T	C	11: 72,440,986 (GRCm39)	S17G	probably benign	Het
Spns3	G	A	11: 72,440,917 (GRCm39)	P40S	probably benign	Het
Srebf1	C	T	11: 60,097,061 (GRCm39)	V256M	probably benign	Het
Tekt1	T	C	11: 72,250,597 (GRCm39)	Q33R	probably benign	Het
Timm22	T	G	11: 76,297,943 (GRCm39)	V18G	probably benign	Het
Tmem102	C	G	11: 69,695,902 (GRCm39)	G53A	possibly damaging	Het
Tmem102	G	C	11: 69,695,927 (GRCm39)	R45G	probably benign	Het
Tmem11	A	G	11: 60,766,658 (GRCm39)		probably benign	Het
Tom1l2	C	T	11: 60,132,682 (GRCm39)	A414T	probably benign	Het
Tomm20l	ACAAGATTC	AC	12: 71,168,758 (GRCm39)		probably null	Het
Top3a	C	T	11: 60,641,410 (GRCm39)	G425S	probably benign	Het
Trim16	T	C	11: 62,731,572 (GRCm39)	V481A	probably benign	Het
Trim16	G	A	11: 62,727,643 (GRCm39)	E322K	probably benign	Het
Trim16	A	AAGC	11: 62,711,521 (GRCm39)		probably benign	Het
Trim16	GA	GAACA	11: 62,711,520 (GRCm39)		probably benign	Het
Trim16	TGAAGA	TGAAGAAGA	11: 62,711,516 (GRCm39)		probably benign	Het
Trim16	G	C	11: 62,711,502 (GRCm39)	V58L	probably benign	Het
Trim16	C	T	11: 62,711,428 (GRCm39)	A33V	probably benign	Het
Trim16	C	A	11: 62,731,675 (GRCm39)	D515E	probably benign	Het
Trim17	G	A	11: 58,856,331 (GRCm39)	M129I	probably benign	Het
Trim17	A	G	11: 58,861,272 (GRCm39)	N259S	probably benign	Het
Trim23	G	A	13: 104,315,395 (GRCm39)	A3T	probably benign	Het
Trim58	A	G	11: 58,542,486 (GRCm39)	N482S	probably benign	Het
Trim58	C	A	11: 58,531,684 (GRCm39)	L131M	possibly damaging	Het
Trmt1l	A	G	1: 151,333,331 (GRCm39)	N642S	possibly damaging	Het
Trpv1	C	G	11: 73,131,427 (GRCm39)	P322A	possibly damaging	Het
Trpv1	C	A	11: 73,145,117 (GRCm39)	D734E	probably benign	Het
Trpv3	A	G	11: 73,174,502 (GRCm39)	T290A	probably benign	Het
Trpv3	G	A	11: 73,169,803 (GRCm39)	A125T	probably benign	Het
Trpv3	C	T	11: 73,160,513 (GRCm39)	A9V	probably benign	Het
Tvp23b	A	C	11: 62,772,769 (GRCm39)	N7H	possibly damaging	Het
Usp43	AGGGC	AGGGCAGGGGATGAACCTCGGGC	11: 67,746,545 (GRCm39)		probably benign	Het
Usp43	C	T	11: 67,747,332 (GRCm39)	G792S	probably benign	Het
Vamp2	C	T	11: 68,979,411 (GRCm39)		probably benign	Het
Vamp2	G	A	11: 68,980,889 (GRCm39)	G124R	possibly damaging	Het
Vmn2r15	G	T	5: 109,434,529 (GRCm39)	P725H	probably damaging	Het
Vmn2r18	T	C	5: 151,508,497 (GRCm39)	D209G	probably benign	Het
Wdr4	C	T	17: 31,731,177 (GRCm39)	G61E	probably damaging	Het
Xaf1	G	C	11: 72,199,856 (GRCm39)	V198L	unknown	Het
Xaf1	GGCT	GGCTGGCCAGCT	11: 72,199,846 (GRCm39)		probably null	Het
Xaf1	T	G	11: 72,199,792 (GRCm39)	C176W	unknown	Het
Xaf1	A	G	11: 72,199,476 (GRCm39)	E71G	probably benign	Het
Xaf1	C	A	11: 72,197,434 (GRCm39)	L137I	probably benign	Het
Xaf1	G	C	11: 72,197,429 (GRCm39)	C135S	probably damaging	Het
Xaf1	G	A	11: 72,197,426 (GRCm39)	R134H	probably benign	Het
Xaf1	T	C	11: 72,199,881 (GRCm39)	L206S	unknown	Het
Zfhx4	C	G	3: 5,308,067 (GRCm39)	S431C	probably damaging	Het
Zfp286	G	A	11: 62,675,782 (GRCm39)	T60M	probably damaging	Het
Zfp286	A	G	11: 62,678,795 (GRCm39)	V44A	probably benign	Het
Zfp287	G	A	11: 62,613,757 (GRCm39)	R225*	probably null	Het
Zfp287	C	T	11: 62,604,633 (GRCm39)	R758H	probably benign	Het
Zfp287	C	G	11: 62,606,175 (GRCm39)	C244S	probably benign	Het
Zfp39	T	C	11: 58,781,274 (GRCm39)	D496G	possibly damaging	Het
Zfp39	G	C	11: 58,781,273 (GRCm39)	D496E	probably benign	Het
Zfp39	G	C	11: 58,781,130 (GRCm39)	T544R	possibly damaging	Het
Zfp39	A	C	11: 58,780,873 (GRCm39)	Y630D	probably benign	Het
Zfp39	G	C	11: 58,780,871 (GRCm39)	Y630*	probably null	Het
Zfp39	T	G	11: 58,791,409 (GRCm39)	S93R	probably benign	Het
Zfp39	G	T	11: 58,791,407 (GRCm39)	S93R	probably benign	Het
Zfp39	T	C	11: 58,782,142 (GRCm39)	K207E	probably benign	Het
Zfp39	A	G	11: 58,782,123 (GRCm39)	I213T	probably benign	Het
Zfp39	T	A	11: 58,781,967 (GRCm39)	H265L	probably damaging	Het
Zfp39	T	C	11: 58,781,526 (GRCm39)	N412S	possibly damaging	Het
Zfp39	G	T	11: 58,781,597 (GRCm39)	N388K	probably benign	Het
Zfp39	A	G	11: 58,781,605 (GRCm39)	S386P	probably benign	Het
Zfp39	A	C	11: 58,781,702 (GRCm39)	H353Q	probably damaging	Het
Zfp39	A	C	11: 58,781,712 (GRCm39)	V350G	probably benign	Het
Zfp39	A	G	11: 58,781,724 (GRCm39)	V346A	probably benign	Het
Zfp39	T	A	11: 58,781,751 (GRCm39)	K337M	probably benign	Het
Zfp672	G	T	11: 58,220,452 (GRCm39)	T49K	unknown	Het
Zfp692	G	T	11: 58,199,859 (GRCm39)	E149D	probably benign	Het
Zfp692	G	A	11: 58,200,844 (GRCm39)	V242I	probably benign	Het
Zzef1	G	A	11: 72,780,008 (GRCm39)	R1927H	probably benign	Het

Other mutations in Myo18a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00089:Myo18a	APN	11	77,738,764 (GRCm39)	missense	probably damaging	1.00
IGL00753:Myo18a	APN	11	77,715,977 (GRCm39)	missense	probably damaging	1.00
IGL01137:Myo18a	APN	11	77,718,655 (GRCm39)	missense	probably damaging	1.00
IGL01536:Myo18a	APN	11	77,711,677 (GRCm39)	missense	probably damaging	1.00
IGL01642:Myo18a	APN	11	77,755,558 (GRCm39)	missense	probably benign	0.07
IGL01728:Myo18a	APN	11	77,668,682 (GRCm39)	missense	probably damaging	0.99
IGL01780:Myo18a	APN	11	77,741,073 (GRCm39)	missense	probably benign	0.02
IGL02286:Myo18a	APN	11	77,668,811 (GRCm39)	nonsense	probably null
IGL02350:Myo18a	APN	11	77,741,073 (GRCm39)	missense	probably benign	0.02
IGL02357:Myo18a	APN	11	77,741,073 (GRCm39)	missense	probably benign	0.02
IGL02420:Myo18a	APN	11	77,709,519 (GRCm39)	missense	possibly damaging	0.81
IGL02643:Myo18a	APN	11	77,668,998 (GRCm39)	missense	possibly damaging	0.67
IGL02667:Myo18a	APN	11	77,748,678 (GRCm39)	splice site	probably benign
IGL02869:Myo18a	APN	11	77,720,699 (GRCm39)	splice site	probably benign
IGL02869:Myo18a	APN	11	77,755,612 (GRCm39)	missense	probably damaging	1.00
IGL02962:Myo18a	APN	11	77,669,061 (GRCm39)	missense	probably damaging	1.00
IGL02963:Myo18a	APN	11	77,732,844 (GRCm39)	splice site	probably benign
IGL03410:Myo18a	APN	11	77,738,830 (GRCm39)	missense	probably damaging	0.99
IGL03050:Myo18a	UTSW	11	77,709,596 (GRCm39)	missense	probably benign	0.00
R0022:Myo18a	UTSW	11	77,734,059 (GRCm39)	critical splice donor site	probably null
R0064:Myo18a	UTSW	11	77,738,170 (GRCm39)	missense	probably damaging	1.00
R0064:Myo18a	UTSW	11	77,738,170 (GRCm39)	missense	probably damaging	1.00
R0098:Myo18a	UTSW	11	77,736,591 (GRCm39)	missense	probably damaging	1.00
R0322:Myo18a	UTSW	11	77,720,626 (GRCm39)	missense	probably damaging	1.00
R0373:Myo18a	UTSW	11	77,711,868 (GRCm39)	missense	probably benign	0.01
R0379:Myo18a	UTSW	11	77,741,632 (GRCm39)	missense	possibly damaging	0.84
R0513:Myo18a	UTSW	11	77,702,420 (GRCm39)	intron	probably benign
R0688:Myo18a	UTSW	11	77,714,966 (GRCm39)	missense	probably damaging	1.00
R0734:Myo18a	UTSW	11	77,738,230 (GRCm39)	missense	probably damaging	1.00
R0790:Myo18a	UTSW	11	77,731,535 (GRCm39)	missense	possibly damaging	0.95
R1099:Myo18a	UTSW	11	77,709,727 (GRCm39)	splice site	probably null
R1103:Myo18a	UTSW	11	77,714,156 (GRCm39)	missense	probably damaging	1.00
R1183:Myo18a	UTSW	11	77,748,571 (GRCm39)	missense	probably damaging	1.00
R1216:Myo18a	UTSW	11	77,709,473 (GRCm39)	missense	probably benign	0.35
R1331:Myo18a	UTSW	11	77,732,405 (GRCm39)	missense	probably benign	0.28
R1479:Myo18a	UTSW	11	77,733,020 (GRCm39)	missense	probably benign	0.04
R1723:Myo18a	UTSW	11	77,744,140 (GRCm39)	missense	probably damaging	0.97
R1742:Myo18a	UTSW	11	77,732,293 (GRCm39)	missense	probably damaging	0.99
R1796:Myo18a	UTSW	11	77,720,170 (GRCm39)	missense	possibly damaging	0.94
R1823:Myo18a	UTSW	11	77,715,923 (GRCm39)	splice site	probably benign
R1827:Myo18a	UTSW	11	77,709,597 (GRCm39)	missense	probably benign	0.00
R2033:Myo18a	UTSW	11	77,733,925 (GRCm39)	splice site	probably null
R2043:Myo18a	UTSW	11	77,714,189 (GRCm39)	missense	probably damaging	0.99
R2105:Myo18a	UTSW	11	77,741,060 (GRCm39)	missense	probably benign
R2191:Myo18a	UTSW	11	77,709,441 (GRCm39)	missense	probably damaging	0.99
R2264:Myo18a	UTSW	11	77,710,798 (GRCm39)	splice site	probably benign
R2370:Myo18a	UTSW	11	77,668,596 (GRCm39)	missense	probably benign	0.03
R3015:Myo18a	UTSW	11	77,749,846 (GRCm39)	intron	probably benign
R3433:Myo18a	UTSW	11	77,708,870 (GRCm39)	splice site	probably null
R3739:Myo18a	UTSW	11	77,736,441 (GRCm39)	missense	probably damaging	1.00
R3825:Myo18a	UTSW	11	77,668,292 (GRCm39)	missense	possibly damaging	0.47
R4056:Myo18a	UTSW	11	77,702,839 (GRCm39)	missense	possibly damaging	0.72
R4163:Myo18a	UTSW	11	77,720,534 (GRCm39)	missense	possibly damaging	0.72
R4184:Myo18a	UTSW	11	77,748,613 (GRCm39)	missense	probably damaging	1.00
R4620:Myo18a	UTSW	11	77,708,773 (GRCm39)	missense	possibly damaging	0.93
R4628:Myo18a	UTSW	11	77,714,962 (GRCm39)	missense	probably damaging	1.00
R4647:Myo18a	UTSW	11	77,708,776 (GRCm39)	missense	probably damaging	1.00
R4701:Myo18a	UTSW	11	77,708,491 (GRCm39)	missense	probably damaging	1.00
R4729:Myo18a	UTSW	11	77,668,511 (GRCm39)	splice site	probably null
R4731:Myo18a	UTSW	11	77,720,585 (GRCm39)	missense	probably benign	0.00
R4739:Myo18a	UTSW	11	77,714,149 (GRCm39)	missense	probably damaging	1.00
R4814:Myo18a	UTSW	11	77,750,062 (GRCm39)	intron	probably benign
R4889:Myo18a	UTSW	11	77,723,238 (GRCm39)	missense	probably damaging	1.00
R4988:Myo18a	UTSW	11	77,736,347 (GRCm39)	critical splice donor site	probably null
R5172:Myo18a	UTSW	11	77,714,924 (GRCm39)	missense	probably damaging	1.00
R5177:Myo18a	UTSW	11	77,755,668 (GRCm39)	utr 3 prime	probably benign
R5394:Myo18a	UTSW	11	77,744,176 (GRCm39)	missense	probably benign	0.14
R5643:Myo18a	UTSW	11	77,745,513 (GRCm39)	missense	probably benign	0.12
R5808:Myo18a	UTSW	11	77,720,127 (GRCm39)	missense	probably benign	0.34
R5871:Myo18a	UTSW	11	77,723,306 (GRCm39)	missense	probably damaging	1.00
R5936:Myo18a	UTSW	11	77,709,039 (GRCm39)	missense	probably damaging	1.00
R6017:Myo18a	UTSW	11	77,732,349 (GRCm39)	missense	probably damaging	0.96
R6053:Myo18a	UTSW	11	77,709,002 (GRCm39)	missense	probably damaging	1.00
R6271:Myo18a	UTSW	11	77,711,635 (GRCm39)	missense	probably damaging	1.00
R6486:Myo18a	UTSW	11	77,755,648 (GRCm39)	missense	possibly damaging	0.83
R6558:Myo18a	UTSW	11	77,741,678 (GRCm39)	missense	probably damaging	0.99
R6884:Myo18a	UTSW	11	77,709,875 (GRCm39)	missense	possibly damaging	0.67
R6983:Myo18a	UTSW	11	77,736,341 (GRCm39)	missense	probably benign	0.06
R6993:Myo18a	UTSW	11	77,749,900 (GRCm39)	intron	probably benign
R7071:Myo18a	UTSW	11	77,714,653 (GRCm39)	missense	probably damaging	1.00
R7074:Myo18a	UTSW	11	77,733,387 (GRCm39)	missense	probably benign	0.03
R7238:Myo18a	UTSW	11	77,733,059 (GRCm39)	missense	probably damaging	0.96
R7328:Myo18a	UTSW	11	77,698,737 (GRCm39)	missense
R7527:Myo18a	UTSW	11	77,734,406 (GRCm39)	missense	probably benign	0.00
R7598:Myo18a	UTSW	11	77,738,172 (GRCm39)	missense	probably damaging	1.00
R7671:Myo18a	UTSW	11	77,750,246 (GRCm39)	missense
R7958:Myo18a	UTSW	11	77,732,383 (GRCm39)	missense	probably damaging	1.00
R8098:Myo18a	UTSW	11	77,736,227 (GRCm39)	missense	probably damaging	0.97
R8168:Myo18a	UTSW	11	77,711,968 (GRCm39)	missense	probably damaging	0.99
R8318:Myo18a	UTSW	11	77,714,215 (GRCm39)	missense	probably benign	0.02
R8685:Myo18a	UTSW	11	77,745,520 (GRCm39)	missense	probably benign	0.00
R8778:Myo18a	UTSW	11	77,714,150 (GRCm39)	missense	probably damaging	1.00
R9023:Myo18a	UTSW	11	77,718,477 (GRCm39)	missense	probably damaging	1.00
R9059:Myo18a	UTSW	11	77,668,899 (GRCm39)	missense	possibly damaging	0.78
R9186:Myo18a	UTSW	11	77,749,847 (GRCm39)	missense
R9321:Myo18a	UTSW	11	77,733,370 (GRCm39)	missense	probably damaging	0.97
R9357:Myo18a	UTSW	11	77,733,014 (GRCm39)	missense	probably damaging	1.00
R9407:Myo18a	UTSW	11	77,709,596 (GRCm39)	missense	probably benign	0.00
R9430:Myo18a	UTSW	11	77,709,410 (GRCm39)	missense	possibly damaging	0.64
R9576:Myo18a	UTSW	11	77,709,827 (GRCm39)	missense	probably damaging	1.00
R9585:Myo18a	UTSW	11	77,709,495 (GRCm39)	missense	probably benign	0.06
R9698:Myo18a	UTSW	11	77,720,681 (GRCm39)	missense	probably damaging	0.99
R9743:Myo18a	UTSW	11	77,723,304 (GRCm39)	missense	probably benign	0.10
R9777:Myo18a	UTSW	11	77,733,080 (GRCm39)	missense	possibly damaging	0.94
Y5407:Myo18a	UTSW	11	77,668,641 (GRCm39)	missense	probably benign	0.44
Z1177:Myo18a	UTSW	11	77,732,821 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CCTTGAATAGAGAAGCCTTTGGAG -3'
(R):5'- GGTCTAGCACTGGGAAGATG -3'

Sequencing Primer
(F):5'- CTTTGGAGGCTTAGAGGAGCACC -3'
(R):5'- TCTAGCACTGGGAAGATGATATG -3'

Posted On

2021-03-08