Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01522:0610010F05Rik'

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89459

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

0610010F05Rik

Ensembl Gene

ENSMUSG00000042208

Gene Name

RIKEN cDNA 0610010F05 gene

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.150) question?

Stock #

IGL01522

Quality Score

Status

Chromosome

Chromosomal Location

23564961-23633639 bp(-) (GRCm38)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

A to G at 23582865 bp

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000136118 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000043356] [ENSMUST00000043356] [ENSMUST00000043356] [ENSMUST00000093267] [ENSMUST00000093267] [ENSMUST00000093267] [ENSMUST00000109532] [ENSMUST00000109532] [ENSMUST00000109532] [ENSMUST00000123909] [ENSMUST00000123909] [ENSMUST00000123909] [ENSMUST00000155903] [ENSMUST00000180260] [ENSMUST00000180260] [ENSMUST00000180260]

Predicted Effect

probably null
Transcript: ENSMUST00000043356

SMART Domains

Protein: ENSMUSP00000044265
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	8	16	N/A	INTRINSIC
Pfam:DUF3342	147	449	5.1e-107	PFAM
low complexity region	565	576	N/A	INTRINSIC
low complexity region	579	596	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000043356

SMART Domains

Protein: ENSMUSP00000044265
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	8	16	N/A	INTRINSIC
Pfam:DUF3342	147	449	5.1e-107	PFAM
low complexity region	565	576	N/A	INTRINSIC
low complexity region	579	596	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000043356

SMART Domains

Protein: ENSMUSP00000044265
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	8	16	N/A	INTRINSIC
Pfam:DUF3342	147	449	5.1e-107	PFAM
low complexity region	565	576	N/A	INTRINSIC
low complexity region	579	596	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000093267

SMART Domains

Protein: ENSMUSP00000090955
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
Pfam:DUF3342	1	303	7.7e-107	PFAM
low complexity region	419	430	N/A	INTRINSIC
low complexity region	433	450	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000093267

SMART Domains

Protein: ENSMUSP00000090955
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
Pfam:DUF3342	1	303	7.7e-107	PFAM
low complexity region	419	430	N/A	INTRINSIC
low complexity region	433	450	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000093267

SMART Domains

Protein: ENSMUSP00000090955
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
Pfam:DUF3342	1	303	7.7e-107	PFAM
low complexity region	419	430	N/A	INTRINSIC
low complexity region	433	450	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000109532

SMART Domains

Protein: ENSMUSP00000105158
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	8	16	N/A	INTRINSIC
Pfam:DUF3342	147	449	5.1e-107	PFAM
low complexity region	565	576	N/A	INTRINSIC
low complexity region	579	596	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000109532

SMART Domains

Protein: ENSMUSP00000105158
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	8	16	N/A	INTRINSIC
Pfam:DUF3342	147	449	5.1e-107	PFAM
low complexity region	565	576	N/A	INTRINSIC
low complexity region	579	596	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000109532

SMART Domains

Protein: ENSMUSP00000105158
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	8	16	N/A	INTRINSIC
Pfam:DUF3342	147	449	5.1e-107	PFAM
low complexity region	565	576	N/A	INTRINSIC
low complexity region	579	596	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000123909

SMART Domains

Protein: ENSMUSP00000117103
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	71	82	N/A	INTRINSIC
low complexity region	85	102	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000123909

SMART Domains

Protein: ENSMUSP00000117103
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	71	82	N/A	INTRINSIC
low complexity region	85	102	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000123909

SMART Domains

Protein: ENSMUSP00000117103
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	71	82	N/A	INTRINSIC
low complexity region	85	102	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000155903

SMART Domains

Protein: ENSMUSP00000137799
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	8	16	N/A	INTRINSIC
Pfam:DUF3342	147	449	1e-106	PFAM
low complexity region	565	576	N/A	INTRINSIC
low complexity region	579	596	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000180260

SMART Domains

Protein: ENSMUSP00000136118
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	8	16	N/A	INTRINSIC
Pfam:DUF3342	147	449	4.5e-107	PFAM
low complexity region	565	576	N/A	INTRINSIC
low complexity region	579	596	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000180260

SMART Domains

Protein: ENSMUSP00000136118
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	8	16	N/A	INTRINSIC
Pfam:DUF3342	147	449	4.5e-107	PFAM
low complexity region	565	576	N/A	INTRINSIC
low complexity region	579	596	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000180260

SMART Domains

Protein: ENSMUSP00000136118
Gene: ENSMUSG00000042208

Domain	Start	End	E-Value	Type
low complexity region	8	16	N/A	INTRINSIC
Pfam:DUF3342	147	449	4.5e-107	PFAM
low complexity region	565	576	N/A	INTRINSIC
low complexity region	579	596	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adamts12	T	C	15: 11,065,159		probably null	Het
Adamts3	T	C	5: 89,702,943	N579S	probably benign	Het
Akr1c19	A	G	13: 4,239,099		probably benign	Het
Ankrd39	T	A	1: 36,542,061	H69L	probably damaging	Het
Apcdd1	T	A	18: 62,952,115	M461K	possibly damaging	Het
Bpifa3	G	A	2: 154,137,582	C209Y	probably damaging	Het
Cep131	T	C	11: 120,067,163	E779G	probably benign	Het
Cep85	T	C	4: 134,152,255	Q394R	probably damaging	Het
Cep85	G	T	4: 134,152,256	Q394K	probably damaging	Het
Clcn6	T	C	4: 148,017,535	Y364C	probably benign	Het
Fetub	G	A	16: 22,929,641	M1I	probably null	Het
Greb1	T	C	12: 16,701,201	I1003V	probably damaging	Het
Hsf3	A	G	X: 96,320,594		probably benign	Het
Jcad	A	G	18: 4,673,312	N358S	probably damaging	Het
Kndc1	T	C	7: 139,913,972		probably benign	Het
Lama1	A	T	17: 67,752,774		probably benign	Het
Mark2	A	G	19: 7,281,238	V50A	probably benign	Het
Mmp7	T	C	9: 7,692,228	W35R	probably damaging	Het
Ndc80	A	G	17: 71,499,325	V578A	probably benign	Het
Nfyc	T	C	4: 120,781,524	E42G	probably damaging	Het
Olfr1164	T	C	2: 88,093,016	K307E	possibly damaging	Het
Olfr1504	A	T	19: 13,887,358	L284*	probably null	Het
Olfr344	A	G	2: 36,569,221	T208A	probably benign	Het
Olfr547	A	T	7: 102,535,184	I146F	probably damaging	Het
Olfr935	A	T	9: 38,995,100	C112S	probably benign	Het
Pcdha11	T	C	18: 37,185,008	F925L	probably damaging	Het
Pdcd1	T	G	1: 94,040,846	R154S	probably benign	Het
Pepd	T	A	7: 34,924,440	D87E	probably benign	Het
Pfn4	A	G	12: 4,770,240	T30A	probably benign	Het
Pgpep1l	A	G	7: 68,237,708	M48T	possibly damaging	Het
Pla2g15	A	G	8: 106,163,116	N340S	probably benign	Het
Plcb4	A	G	2: 136,002,627	D155G	probably damaging	Het
Plg	G	A	17: 12,404,069	G499S	probably damaging	Het
Plin3	C	T	17: 56,280,799	W305*	probably null	Het
Polq	C	A	16: 37,027,903	L291I	probably damaging	Het
Sdf2l1	T	A	16: 17,132,150	H54L	probably damaging	Het
Slc38a2	C	T	15: 96,693,055	D276N	possibly damaging	Het
Syk	A	G	13: 52,643,061	T576A	probably benign	Het
Tas2r119	G	A	15: 32,178,193	V302I	probably benign	Het
Uso1	T	C	5: 92,181,419	F389L	probably damaging	Het
Wwc2	T	A	8: 47,868,633	Y482F	unknown	Het

Other mutations in 0610010F05Rik

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01133:0610010F05Rik	APN	11	23595434	missense	probably damaging	1.00
IGL01444:0610010F05Rik	APN	11	23620225	splice site	probably benign
IGL01819:0610010F05Rik	APN	11	23584561	missense	probably benign	0.29
IGL02470:0610010F05Rik	APN	11	23615222	missense	probably damaging	0.99
IGL03046:0610010F05Rik	UTSW	11	23615150	missense	possibly damaging	0.77
R0139:0610010F05Rik	UTSW	11	23620214	splice site	probably benign
R0334:0610010F05Rik	UTSW	11	23617129	splice site	probably benign
R0646:0610010F05Rik	UTSW	11	23575491	missense	probably damaging	0.99
R1078:0610010F05Rik	UTSW	11	23611762	missense	probably benign	0.45
R1263:0610010F05Rik	UTSW	11	23620278	nonsense	probably null
R1471:0610010F05Rik	UTSW	11	23615222	missense	probably damaging	0.99
R1568:0610010F05Rik	UTSW	11	23589971	missense	probably damaging	1.00
R2163:0610010F05Rik	UTSW	11	23576826	splice site	probably benign
R2318:0610010F05Rik	UTSW	11	23588701	missense	probably damaging	1.00
R2426:0610010F05Rik	UTSW	11	23576801	missense	probably damaging	1.00
R4373:0610010F05Rik	UTSW	11	23615265	splice site	probably null
R4688:0610010F05Rik	UTSW	11	23593449	missense	probably benign
R4816:0610010F05Rik	UTSW	11	23615243	missense	possibly damaging	0.67
R5046:0610010F05Rik	UTSW	11	23620354	missense	probably benign	0.23
R5156:0610010F05Rik	UTSW	11	23593424	critical splice donor site	probably null
R5249:0610010F05Rik	UTSW	11	23575483	makesense	probably null
R5615:0610010F05Rik	UTSW	11	23606759	missense	probably damaging	0.96
R6758:0610010F05Rik	UTSW	11	23588475	splice site	probably null
R6860:0610010F05Rik	UTSW	11	23625100	missense	probably damaging	1.00
R6910:0610010F05Rik	UTSW	11	23620447	missense	probably damaging	0.99
R7255:0610010F05Rik	UTSW	11	23620465	missense	probably benign	0.41
R7286:0610010F05Rik	UTSW	11	23622479	missense	probably benign	0.07
R7603:0610010F05Rik	UTSW	11	23566191	missense	probably benign
R7618:0610010F05Rik	UTSW	11	23584550	missense	possibly damaging	0.91
R7717:0610010F05Rik	UTSW	11	23606757	missense	probably benign	0.05
R8110:0610010F05Rik	UTSW	11	23576764	missense	probably benign
X0026:0610010F05Rik	UTSW	11	23576767	missense	probably benign	0.00
X0067:0610010F05Rik	UTSW	11	23593420	splice site	probably null
Z1177:0610010F05Rik	UTSW	11	23624960	missense	probably benign	0.38

Posted On

2013-12-03