Incidental Mutation 'R1840:Ranbp2'
| ID |
205722 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ranbp2
|
| Ensembl Gene |
ENSMUSG00000003226 |
| Gene Name |
RAN binding protein 2 |
| Synonyms |
A430087B05Rik |
| MMRRC Submission |
039866-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1840 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
58282674-58329977 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 58314588 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 1769
(N1769K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000003310
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000003310]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000003310
AA Change: N1769K
PolyPhen 2
Score 0.413 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000003310
Gene: ENSMUSG00000003226
AA Change: N1769K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TPR_1
|
60 |
93 |
1.8e-7 |
PFAM |
|
Pfam:TPR_8
|
60 |
93 |
8.9e-6 |
PFAM |
|
low complexity region
|
235 |
247 |
N/A |
INTRINSIC |
|
low complexity region
|
778 |
801 |
N/A |
INTRINSIC |
|
coiled coil region
|
808 |
832 |
N/A |
INTRINSIC |
|
RanBD
|
1166 |
1295 |
6.47e-64 |
SMART |
|
ZnF_RBZ
|
1348 |
1372 |
5.49e-2 |
SMART |
|
ZnF_RBZ
|
1412 |
1436 |
3.06e-6 |
SMART |
|
ZnF_RBZ
|
1471 |
1495 |
4.16e-8 |
SMART |
|
ZnF_RBZ
|
1500 |
1524 |
4.57e-5 |
SMART |
|
ZnF_RBZ
|
1560 |
1584 |
3.52e-6 |
SMART |
|
ZnF_RBZ
|
1619 |
1643 |
1.35e-7 |
SMART |
|
RanBD
|
1850 |
1979 |
2.84e-60 |
SMART |
|
low complexity region
|
2034 |
2048 |
N/A |
INTRINSIC |
|
low complexity region
|
2069 |
2090 |
N/A |
INTRINSIC |
|
low complexity region
|
2106 |
2121 |
N/A |
INTRINSIC |
|
RanBD
|
2147 |
2276 |
4.96e-83 |
SMART |
|
low complexity region
|
2310 |
2317 |
N/A |
INTRINSIC |
|
low complexity region
|
2328 |
2342 |
N/A |
INTRINSIC |
|
Pfam:IR1-M
|
2468 |
2530 |
2.5e-27 |
PFAM |
|
Pfam:IR1-M
|
2544 |
2604 |
7e-30 |
PFAM |
|
low complexity region
|
2673 |
2684 |
N/A |
INTRINSIC |
|
low complexity region
|
2722 |
2732 |
N/A |
INTRINSIC |
|
RanBD
|
2741 |
2869 |
5e-79 |
SMART |
|
Pfam:Pro_isomerase
|
2896 |
3052 |
4.5e-45 |
PFAM |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.8%
- 10x: 95.2%
- 20x: 92.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap allele display embryonic lethality. Heterozygous mice on some backgrounds display reduced ATP levels in the CNS, decreased glucose clearance, decreased weight gain on a high fat diet, and reduced scotopic responses. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 118 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2510009E07Rik |
T |
A |
16: 21,472,236 (GRCm39) |
M85L |
probably benign |
Het |
| Aatk |
T |
G |
11: 119,904,558 (GRCm39) |
D206A |
probably damaging |
Het |
| Agap3 |
A |
G |
5: 24,705,229 (GRCm39) |
D719G |
probably damaging |
Het |
| Agrn |
G |
A |
4: 156,251,872 (GRCm39) |
R1797C |
probably damaging |
Het |
| Ascc3 |
T |
A |
10: 50,566,257 (GRCm39) |
M734K |
probably benign |
Het |
| Asph |
T |
A |
4: 9,601,340 (GRCm39) |
M136L |
possibly damaging |
Het |
| Atm |
A |
T |
9: 53,367,830 (GRCm39) |
V2431E |
probably damaging |
Het |
| Atp2b1 |
A |
G |
10: 98,858,791 (GRCm39) |
H1158R |
probably benign |
Het |
| Atxn7l1 |
A |
G |
12: 33,421,032 (GRCm39) |
|
probably null |
Het |
| BC024139 |
G |
T |
15: 76,004,842 (GRCm39) |
S611R |
probably benign |
Het |
| Becn1 |
C |
T |
11: 101,186,392 (GRCm39) |
G105S |
probably damaging |
Het |
| Bud13 |
A |
G |
9: 46,197,706 (GRCm39) |
E70G |
probably damaging |
Het |
| Cacul1 |
A |
T |
19: 60,522,688 (GRCm39) |
L282* |
probably null |
Het |
| Catspere2 |
A |
G |
1: 177,830,581 (GRCm39) |
D30G |
possibly damaging |
Het |
| Ccar1 |
T |
A |
10: 62,599,289 (GRCm39) |
K614M |
probably damaging |
Het |
| Cd96 |
T |
C |
16: 45,919,455 (GRCm39) |
T189A |
probably benign |
Het |
| Cdh5 |
C |
A |
8: 104,853,248 (GRCm39) |
Y189* |
probably null |
Het |
| Chka |
A |
G |
19: 3,936,460 (GRCm39) |
N284S |
probably benign |
Het |
| Cntn6 |
A |
T |
6: 104,751,441 (GRCm39) |
I366F |
probably damaging |
Het |
| Csmd3 |
C |
T |
15: 47,470,560 (GRCm39) |
G3372E |
probably damaging |
Het |
| Cyp4f16 |
T |
C |
17: 32,761,980 (GRCm39) |
|
probably null |
Het |
| Dcaf6 |
A |
G |
1: 165,227,317 (GRCm39) |
V270A |
probably damaging |
Het |
| Ddx60 |
T |
A |
8: 62,422,587 (GRCm39) |
I608N |
probably damaging |
Het |
| Dnah9 |
A |
T |
11: 65,725,024 (GRCm39) |
C1849* |
probably null |
Het |
| Eci3 |
C |
A |
13: 35,144,024 (GRCm39) |
V34L |
probably benign |
Het |
| Eif1ad9 |
T |
C |
12: 88,296,181 (GRCm39) |
V53A |
probably benign |
Het |
| Entrep2 |
C |
A |
7: 64,408,943 (GRCm39) |
V484L |
probably benign |
Het |
| Epha1 |
C |
T |
6: 42,340,522 (GRCm39) |
R583H |
probably damaging |
Het |
| Erbin |
A |
T |
13: 103,971,455 (GRCm39) |
N720K |
probably benign |
Het |
| Eya1 |
T |
A |
1: 14,299,728 (GRCm39) |
R346* |
probably null |
Het |
| Fhdc1 |
G |
A |
3: 84,353,128 (GRCm39) |
T699I |
possibly damaging |
Het |
| Flvcr2 |
T |
C |
12: 85,849,995 (GRCm39) |
V427A |
possibly damaging |
Het |
| Frey1 |
T |
C |
2: 92,213,554 (GRCm39) |
S36P |
probably benign |
Het |
| Fzd9 |
T |
A |
5: 135,278,425 (GRCm39) |
T487S |
probably benign |
Het |
| Gas2l3 |
T |
C |
10: 89,258,113 (GRCm39) |
Y160C |
possibly damaging |
Het |
| Gm10269 |
T |
C |
18: 20,815,866 (GRCm39) |
K52R |
probably damaging |
Het |
| Gm8674 |
A |
T |
13: 50,055,801 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr61 |
A |
G |
3: 108,057,797 (GRCm39) |
V288A |
possibly damaging |
Het |
| Gramd4 |
T |
C |
15: 86,014,393 (GRCm39) |
|
probably null |
Het |
| Gtpbp4 |
A |
G |
13: 9,029,500 (GRCm39) |
L403P |
probably benign |
Het |
| H6pd |
A |
T |
4: 150,066,507 (GRCm39) |
D626E |
possibly damaging |
Het |
| Herc6 |
T |
A |
6: 57,635,091 (GRCm39) |
L769* |
probably null |
Het |
| Hes5 |
A |
G |
4: 155,045,711 (GRCm39) |
K58R |
probably damaging |
Het |
| Heyl |
A |
G |
4: 123,135,183 (GRCm39) |
I59V |
probably damaging |
Het |
| Hpca |
A |
G |
4: 129,012,393 (GRCm39) |
F48L |
probably damaging |
Het |
| Ice1 |
C |
T |
13: 70,754,337 (GRCm39) |
R583Q |
probably benign |
Het |
| Ints2 |
C |
T |
11: 86,123,911 (GRCm39) |
G626R |
probably damaging |
Het |
| Kansl1l |
T |
A |
1: 66,817,191 (GRCm39) |
I390F |
probably damaging |
Het |
| Kat5 |
C |
T |
19: 5,659,266 (GRCm39) |
V95M |
possibly damaging |
Het |
| Kcnh4 |
T |
A |
11: 100,636,167 (GRCm39) |
I827F |
possibly damaging |
Het |
| Kif1b |
C |
T |
4: 149,272,589 (GRCm39) |
R138Q |
probably damaging |
Het |
| Kirrel1 |
C |
T |
3: 86,996,458 (GRCm39) |
M380I |
probably null |
Het |
| Lats1 |
T |
A |
10: 7,586,703 (GRCm39) |
L955* |
probably null |
Het |
| Ldlrad2 |
A |
C |
4: 137,299,495 (GRCm39) |
C110G |
possibly damaging |
Het |
| Lgi3 |
G |
A |
14: 70,772,216 (GRCm39) |
|
probably null |
Het |
| Lingo1 |
A |
G |
9: 56,527,842 (GRCm39) |
M249T |
probably benign |
Het |
| Lrig3 |
A |
T |
10: 125,849,258 (GRCm39) |
R993* |
probably null |
Het |
| Lsm14b |
T |
A |
2: 179,668,521 (GRCm39) |
I74N |
probably damaging |
Het |
| Lyplal1 |
T |
A |
1: 185,832,414 (GRCm39) |
I114F |
probably damaging |
Het |
| Mmp15 |
A |
G |
8: 96,092,048 (GRCm39) |
Y86C |
probably damaging |
Het |
| Myh2 |
A |
G |
11: 67,077,313 (GRCm39) |
E816G |
probably benign |
Het |
| Myo5c |
A |
G |
9: 75,157,017 (GRCm39) |
N151S |
probably damaging |
Het |
| Nckap1 |
T |
A |
2: 80,332,594 (GRCm39) |
E1082V |
possibly damaging |
Het |
| Nrg4 |
A |
C |
9: 55,189,890 (GRCm39) |
|
probably benign |
Het |
| Nrp2 |
T |
C |
1: 62,777,498 (GRCm39) |
L101P |
probably damaging |
Het |
| Or14j5 |
A |
T |
17: 38,161,639 (GRCm39) |
D52V |
probably damaging |
Het |
| Or2at1 |
A |
T |
7: 99,416,803 (GRCm39) |
T145S |
probably benign |
Het |
| Or4p19 |
T |
C |
2: 88,242,411 (GRCm39) |
D197G |
probably benign |
Het |
| Or51q1c |
A |
G |
7: 103,653,324 (GRCm39) |
I281V |
probably benign |
Het |
| Or5ak22 |
G |
A |
2: 85,230,512 (GRCm39) |
R122C |
probably benign |
Het |
| Parp14 |
T |
A |
16: 35,683,819 (GRCm39) |
E169V |
probably damaging |
Het |
| Pcolce2 |
A |
T |
9: 95,552,256 (GRCm39) |
N130Y |
probably benign |
Het |
| Pcolce2 |
G |
A |
9: 95,552,170 (GRCm39) |
R101H |
probably damaging |
Het |
| Plscr1 |
A |
T |
9: 92,140,127 (GRCm39) |
S5C |
unknown |
Het |
| Plxdc2 |
T |
C |
2: 16,674,667 (GRCm39) |
V338A |
probably benign |
Het |
| Psg23 |
T |
A |
7: 18,344,363 (GRCm39) |
N364I |
possibly damaging |
Het |
| Psmg4 |
A |
G |
13: 34,362,039 (GRCm39) |
E109G |
probably damaging |
Het |
| Ptk2 |
T |
C |
15: 73,082,733 (GRCm39) |
E908G |
probably damaging |
Het |
| Ptpn14 |
G |
A |
1: 189,519,048 (GRCm39) |
R26H |
probably damaging |
Het |
| Rbm14 |
C |
T |
19: 4,851,823 (GRCm39) |
|
probably benign |
Het |
| Rgs7 |
A |
T |
1: 174,980,714 (GRCm39) |
D103E |
probably damaging |
Het |
| Rmnd5a |
G |
A |
6: 71,375,439 (GRCm39) |
L80F |
probably benign |
Het |
| Rock2 |
T |
A |
12: 16,978,990 (GRCm39) |
D93E |
probably benign |
Het |
| Rps6ka6 |
A |
G |
X: 110,330,629 (GRCm39) |
I246T |
possibly damaging |
Het |
| Rubcn |
T |
C |
16: 32,646,542 (GRCm39) |
M803V |
possibly damaging |
Het |
| Ryr3 |
T |
C |
2: 112,581,165 (GRCm39) |
Y2889C |
probably damaging |
Het |
| Sall2 |
T |
C |
14: 52,551,182 (GRCm39) |
N671S |
probably damaging |
Het |
| Selplg |
T |
C |
5: 113,957,905 (GRCm39) |
T134A |
possibly damaging |
Het |
| Sez6 |
C |
A |
11: 77,844,543 (GRCm39) |
T122N |
possibly damaging |
Het |
| Slc9b1 |
T |
A |
3: 135,063,229 (GRCm39) |
D4E |
unknown |
Het |
| Smim18 |
A |
G |
8: 34,232,376 (GRCm39) |
M81T |
probably benign |
Het |
| Snap91 |
A |
T |
9: 86,697,518 (GRCm39) |
H281Q |
probably damaging |
Het |
| Sparc |
C |
A |
11: 55,286,692 (GRCm39) |
C302F |
probably damaging |
Het |
| Spg11 |
A |
G |
2: 121,932,237 (GRCm39) |
L535P |
probably damaging |
Het |
| Spsb1 |
G |
A |
4: 149,991,088 (GRCm39) |
T160I |
probably damaging |
Het |
| Stra6 |
A |
G |
9: 58,047,813 (GRCm39) |
N128S |
probably benign |
Het |
| Strc |
T |
C |
2: 121,209,777 (GRCm39) |
E182G |
probably damaging |
Het |
| Sult2a6 |
A |
G |
7: 13,988,754 (GRCm39) |
M2T |
probably benign |
Het |
| Sv2c |
T |
C |
13: 96,118,352 (GRCm39) |
N499S |
probably benign |
Het |
| Szt2 |
A |
T |
4: 118,222,854 (GRCm39) |
|
probably benign |
Het |
| Tbx20 |
A |
T |
9: 24,636,972 (GRCm39) |
S372T |
probably benign |
Het |
| Tcp11l2 |
T |
A |
10: 84,440,463 (GRCm39) |
S289T |
probably damaging |
Het |
| Tdrd1 |
A |
G |
19: 56,830,744 (GRCm39) |
E259G |
probably damaging |
Het |
| Thsd7a |
T |
A |
6: 12,330,973 (GRCm39) |
I1390L |
probably benign |
Het |
| Tln2 |
G |
A |
9: 67,249,325 (GRCm39) |
R921W |
probably damaging |
Het |
| Tmem126a |
C |
A |
7: 90,102,092 (GRCm39) |
G36* |
probably null |
Het |
| Tmem245 |
C |
T |
4: 56,903,947 (GRCm39) |
V606I |
probably benign |
Het |
| Trpm6 |
A |
G |
19: 18,843,631 (GRCm39) |
D1665G |
probably benign |
Het |
| Ubac2 |
T |
G |
14: 122,231,674 (GRCm39) |
V200G |
probably benign |
Het |
| Ubr5 |
G |
A |
15: 37,981,161 (GRCm39) |
A2372V |
possibly damaging |
Het |
| Ugcg |
C |
T |
4: 59,219,517 (GRCm39) |
P285S |
probably damaging |
Het |
| Vmn1r9 |
T |
C |
6: 57,048,522 (GRCm39) |
V199A |
probably damaging |
Het |
| Vmn2r118 |
T |
A |
17: 55,917,406 (GRCm39) |
K369* |
probably null |
Het |
| Xpnpep3 |
G |
T |
15: 81,311,554 (GRCm39) |
A87S |
probably benign |
Het |
| Zc3h7a |
C |
T |
16: 10,978,890 (GRCm39) |
R95H |
probably damaging |
Het |
| Zdhhc11 |
A |
G |
13: 74,122,771 (GRCm39) |
N169S |
probably damaging |
Het |
| Zfp62 |
T |
A |
11: 49,107,215 (GRCm39) |
D435E |
probably damaging |
Het |
| Zfyve16 |
T |
C |
13: 92,648,033 (GRCm39) |
D1007G |
possibly damaging |
Het |
|
| Other mutations in Ranbp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00229:Ranbp2
|
APN |
10 |
58,313,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00336:Ranbp2
|
APN |
10 |
58,287,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00486:Ranbp2
|
APN |
10 |
58,313,434 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL00800:Ranbp2
|
APN |
10 |
58,326,526 (GRCm39) |
missense |
probably benign |
|
|
IGL00834:Ranbp2
|
APN |
10 |
58,289,145 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00852:Ranbp2
|
APN |
10 |
58,313,723 (GRCm39) |
missense |
probably benign |
|
|
IGL00984:Ranbp2
|
APN |
10 |
58,297,786 (GRCm39) |
nonsense |
probably null |
|
|
IGL01299:Ranbp2
|
APN |
10 |
58,328,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01325:Ranbp2
|
APN |
10 |
58,312,120 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01444:Ranbp2
|
APN |
10 |
58,311,122 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL01545:Ranbp2
|
APN |
10 |
58,314,703 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL01619:Ranbp2
|
APN |
10 |
58,299,900 (GRCm39) |
splice site |
probably null |
|
|
IGL01782:Ranbp2
|
APN |
10 |
58,314,131 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02020:Ranbp2
|
APN |
10 |
58,315,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02096:Ranbp2
|
APN |
10 |
58,297,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02182:Ranbp2
|
APN |
10 |
58,321,582 (GRCm39) |
nonsense |
probably null |
|
|
IGL02211:Ranbp2
|
APN |
10 |
58,314,064 (GRCm39) |
missense |
probably benign |
|
|
IGL02249:Ranbp2
|
APN |
10 |
58,315,900 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02268:Ranbp2
|
APN |
10 |
58,329,475 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02421:Ranbp2
|
APN |
10 |
58,316,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03080:Ranbp2
|
APN |
10 |
58,312,613 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03119:Ranbp2
|
APN |
10 |
58,287,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03206:Ranbp2
|
APN |
10 |
58,301,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03237:Ranbp2
|
APN |
10 |
58,328,783 (GRCm39) |
missense |
probably damaging |
0.98 |
|
En_passant
|
UTSW |
10 |
58,287,839 (GRCm39) |
missense |
probably damaging |
1.00 |
|
red_river
|
UTSW |
10 |
58,301,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02799:Ranbp2
|
UTSW |
10 |
58,316,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0058:Ranbp2
|
UTSW |
10 |
58,316,353 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0058:Ranbp2
|
UTSW |
10 |
58,316,353 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0145:Ranbp2
|
UTSW |
10 |
58,315,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0309:Ranbp2
|
UTSW |
10 |
58,315,690 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0375:Ranbp2
|
UTSW |
10 |
58,313,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0441:Ranbp2
|
UTSW |
10 |
58,321,590 (GRCm39) |
missense |
probably benign |
0.40 |
|
R0494:Ranbp2
|
UTSW |
10 |
58,303,254 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0542:Ranbp2
|
UTSW |
10 |
58,314,236 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0565:Ranbp2
|
UTSW |
10 |
58,312,158 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0608:Ranbp2
|
UTSW |
10 |
58,329,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0661:Ranbp2
|
UTSW |
10 |
58,314,555 (GRCm39) |
missense |
probably benign |
|
|
R0670:Ranbp2
|
UTSW |
10 |
58,316,520 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0760:Ranbp2
|
UTSW |
10 |
58,312,613 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R0811:Ranbp2
|
UTSW |
10 |
58,301,351 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0812:Ranbp2
|
UTSW |
10 |
58,301,351 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1180:Ranbp2
|
UTSW |
10 |
58,301,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1196:Ranbp2
|
UTSW |
10 |
58,312,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1216:Ranbp2
|
UTSW |
10 |
58,319,034 (GRCm39) |
splice site |
probably benign |
|
|
R1374:Ranbp2
|
UTSW |
10 |
58,321,715 (GRCm39) |
splice site |
probably benign |
|
|
R1541:Ranbp2
|
UTSW |
10 |
58,318,916 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1589:Ranbp2
|
UTSW |
10 |
58,299,808 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1711:Ranbp2
|
UTSW |
10 |
58,296,341 (GRCm39) |
missense |
probably benign |
0.11 |
|
R1761:Ranbp2
|
UTSW |
10 |
58,321,563 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1831:Ranbp2
|
UTSW |
10 |
58,315,044 (GRCm39) |
nonsense |
probably null |
|
|
R1869:Ranbp2
|
UTSW |
10 |
58,328,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1871:Ranbp2
|
UTSW |
10 |
58,328,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1892:Ranbp2
|
UTSW |
10 |
58,299,921 (GRCm39) |
missense |
probably benign |
0.36 |
|
R2270:Ranbp2
|
UTSW |
10 |
58,291,749 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2363:Ranbp2
|
UTSW |
10 |
58,314,758 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R3844:Ranbp2
|
UTSW |
10 |
58,313,717 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R3937:Ranbp2
|
UTSW |
10 |
58,312,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3938:Ranbp2
|
UTSW |
10 |
58,312,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4025:Ranbp2
|
UTSW |
10 |
58,316,378 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4183:Ranbp2
|
UTSW |
10 |
58,301,488 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4247:Ranbp2
|
UTSW |
10 |
58,314,686 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R4334:Ranbp2
|
UTSW |
10 |
58,299,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4656:Ranbp2
|
UTSW |
10 |
58,289,244 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4746:Ranbp2
|
UTSW |
10 |
58,328,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4852:Ranbp2
|
UTSW |
10 |
58,312,878 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4863:Ranbp2
|
UTSW |
10 |
58,328,243 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5011:Ranbp2
|
UTSW |
10 |
58,297,717 (GRCm39) |
missense |
probably benign |
0.36 |
|
R5014:Ranbp2
|
UTSW |
10 |
58,299,942 (GRCm39) |
missense |
probably benign |
0.40 |
|
R5145:Ranbp2
|
UTSW |
10 |
58,315,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5178:Ranbp2
|
UTSW |
10 |
58,312,607 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5199:Ranbp2
|
UTSW |
10 |
58,300,265 (GRCm39) |
missense |
probably benign |
|
|
R5294:Ranbp2
|
UTSW |
10 |
58,314,490 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5508:Ranbp2
|
UTSW |
10 |
58,315,827 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5511:Ranbp2
|
UTSW |
10 |
58,329,561 (GRCm39) |
missense |
probably benign |
0.29 |
|
R5575:Ranbp2
|
UTSW |
10 |
58,328,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5617:Ranbp2
|
UTSW |
10 |
58,301,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5630:Ranbp2
|
UTSW |
10 |
58,314,898 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5733:Ranbp2
|
UTSW |
10 |
58,321,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5751:Ranbp2
|
UTSW |
10 |
58,300,086 (GRCm39) |
splice site |
probably null |
|
|
R5767:Ranbp2
|
UTSW |
10 |
58,312,647 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6122:Ranbp2
|
UTSW |
10 |
58,301,351 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6147:Ranbp2
|
UTSW |
10 |
58,315,250 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6286:Ranbp2
|
UTSW |
10 |
58,315,394 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6344:Ranbp2
|
UTSW |
10 |
58,319,708 (GRCm39) |
splice site |
probably null |
|
|
R6452:Ranbp2
|
UTSW |
10 |
58,313,979 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6487:Ranbp2
|
UTSW |
10 |
58,321,563 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6620:Ranbp2
|
UTSW |
10 |
58,291,629 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6759:Ranbp2
|
UTSW |
10 |
58,293,559 (GRCm39) |
nonsense |
probably null |
|
|
R7010:Ranbp2
|
UTSW |
10 |
58,290,393 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7071:Ranbp2
|
UTSW |
10 |
58,328,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7083:Ranbp2
|
UTSW |
10 |
58,315,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7088:Ranbp2
|
UTSW |
10 |
58,299,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7102:Ranbp2
|
UTSW |
10 |
58,299,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7194:Ranbp2
|
UTSW |
10 |
58,312,591 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7217:Ranbp2
|
UTSW |
10 |
58,287,839 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7318:Ranbp2
|
UTSW |
10 |
58,318,909 (GRCm39) |
nonsense |
probably null |
|
|
R7341:Ranbp2
|
UTSW |
10 |
58,321,619 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7398:Ranbp2
|
UTSW |
10 |
58,303,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7424:Ranbp2
|
UTSW |
10 |
58,315,016 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7727:Ranbp2
|
UTSW |
10 |
58,291,260 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7795:Ranbp2
|
UTSW |
10 |
58,319,729 (GRCm39) |
nonsense |
probably null |
|
|
R7812:Ranbp2
|
UTSW |
10 |
58,303,224 (GRCm39) |
missense |
probably benign |
|
|
R7845:Ranbp2
|
UTSW |
10 |
58,282,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7875:Ranbp2
|
UTSW |
10 |
58,314,277 (GRCm39) |
nonsense |
probably null |
|
|
R7934:Ranbp2
|
UTSW |
10 |
58,312,297 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8022:Ranbp2
|
UTSW |
10 |
58,321,683 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8050:Ranbp2
|
UTSW |
10 |
58,315,441 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8100:Ranbp2
|
UTSW |
10 |
58,326,470 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R8194:Ranbp2
|
UTSW |
10 |
58,291,747 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8258:Ranbp2
|
UTSW |
10 |
58,291,755 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8259:Ranbp2
|
UTSW |
10 |
58,291,755 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8461:Ranbp2
|
UTSW |
10 |
58,312,216 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8722:Ranbp2
|
UTSW |
10 |
58,312,049 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8755:Ranbp2
|
UTSW |
10 |
58,300,969 (GRCm39) |
nonsense |
probably null |
|
|
R8794:Ranbp2
|
UTSW |
10 |
58,328,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8879:Ranbp2
|
UTSW |
10 |
58,313,711 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8994:Ranbp2
|
UTSW |
10 |
58,315,891 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9023:Ranbp2
|
UTSW |
10 |
58,315,343 (GRCm39) |
nonsense |
probably null |
|
|
R9124:Ranbp2
|
UTSW |
10 |
58,328,719 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9133:Ranbp2
|
UTSW |
10 |
58,313,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9145:Ranbp2
|
UTSW |
10 |
58,291,736 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9190:Ranbp2
|
UTSW |
10 |
58,313,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9369:Ranbp2
|
UTSW |
10 |
58,316,486 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9394:Ranbp2
|
UTSW |
10 |
58,291,698 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9642:Ranbp2
|
UTSW |
10 |
58,318,907 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9673:Ranbp2
|
UTSW |
10 |
58,300,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0018:Ranbp2
|
UTSW |
10 |
58,314,406 (GRCm39) |
missense |
probably benign |
0.13 |
|
X0022:Ranbp2
|
UTSW |
10 |
58,300,977 (GRCm39) |
missense |
probably benign |
0.33 |
|
Z1088:Ranbp2
|
UTSW |
10 |
58,328,715 (GRCm39) |
missense |
probably benign |
0.35 |
|
Z1088:Ranbp2
|
UTSW |
10 |
58,313,805 (GRCm39) |
frame shift |
probably null |
|
|
Z1088:Ranbp2
|
UTSW |
10 |
58,313,794 (GRCm39) |
frame shift |
probably null |
|
|
Z1176:Ranbp2
|
UTSW |
10 |
58,297,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ranbp2
|
UTSW |
10 |
58,329,713 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTTCAGGGTGGCTCTAATACAG -3'
(R):5'- TCTGGCATCTGCACTACTGG -3'
Sequencing Primer
(F):5'- GGGTGGCTCTAATACAGAATTTAAG -3'
(R):5'- GCACTACTGGCTCAAAATGGATGTC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation