Mutagenetix > Incidental Mutation

Incidental Mutation 'R1952:Nbeal1'

217350

Institutional Source

Beutler Lab

Gene Symbol

Nbeal1

Ensembl Gene

ENSMUSG00000073664

Gene Name

neurobeachin like 1

Synonyms

A530083I02Rik, A530050O19Rik, ALS2CR17, 2310076G13Rik

MMRRC Submission

039966-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1952 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

60219758-60377487 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 60273999 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 409 (V409A)

Ref Sequence

ENSEMBL: ENSMUSP00000124056 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000160834] [ENSMUST00000160980]

AlphaFold

E9PYP2

Predicted Effect

probably damaging
Transcript: ENSMUST00000035569
AA Change: V409A

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000049393
Gene: ENSMUSG00000073664
AA Change: V409A

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
low complexity region	719	735	N/A	INTRINSIC
Pfam:DUF4704	851	1130	3.4e-39	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
Pfam:DUF4800	1575	1828	6.3e-126	PFAM
coiled coil region	1859	1882	N/A	INTRINSIC
Pfam:PH_BEACH	1889	1975	2e-24	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000160834
AA Change: V409A

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000124056
Gene: ENSMUSG00000073664
AA Change: V409A

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
Pfam:Laminin_G_3	567	801	8.3e-9	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
low complexity region	1849	1865	N/A	INTRINSIC
Pfam:PH_BEACH	1882	1975	4.9e-32	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000160980
AA Change: V165A

PolyPhen 2 Score 0.748 (Sensitivity: 0.85; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000125147
Gene: ENSMUSG00000073664
AA Change: V165A

Domain	Start	End	E-Value	Type
low complexity region	278	297	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000185573

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000188450

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.7%
20x: 93.9%

Validation Efficiency

Allele List at MGI

All alleles(16) : Targeted(1) Gene trapped(15)

Other mutations in this stock

Total: 75 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700024G13Rik	A	G	14: 32,110,293 (GRCm39)	V6A	possibly damaging	Het
Accsl	G	T	2: 93,689,778 (GRCm39)	H376Q	probably damaging	Het
Adgrg1	T	C	8: 95,735,119 (GRCm39)		probably null	Het
Alyref	C	G	11: 120,486,758 (GRCm39)	V168L	probably damaging	Het
Ankrd12	T	C	17: 66,338,566 (GRCm39)	D128G	probably damaging	Het
Bcl2l14	A	G	6: 134,409,329 (GRCm39)	Y301C	probably damaging	Het
Camsap3	A	G	8: 3,654,789 (GRCm39)	T804A	probably damaging	Het
Capn11	A	T	17: 45,953,885 (GRCm39)	W154R	probably damaging	Het
Cd44	T	A	2: 102,683,432 (GRCm39)	T201S	probably damaging	Het
Cers4	G	A	8: 4,573,461 (GRCm39)	W319*	probably null	Het
Col27a1	T	A	4: 63,202,130 (GRCm39)		probably null	Het
Crnkl1	G	A	2: 145,770,120 (GRCm39)	A241V	probably damaging	Het
Cyp2c68	T	C	19: 39,700,972 (GRCm39)	Y282C	probably benign	Het
Dmd	T	A	X: 82,874,123 (GRCm39)	I1342N	probably damaging	Het
Dusp7	T	A	9: 106,248,028 (GRCm39)	C219S	probably benign	Het
Epha7	A	G	4: 28,950,474 (GRCm39)	N759S	probably damaging	Het
Fat1	T	C	8: 45,486,963 (GRCm39)	V3413A	probably benign	Het
Gls2	A	G	10: 128,045,231 (GRCm39)	H576R	probably benign	Het
Gm4884	G	A	7: 40,693,671 (GRCm39)	V547M	probably benign	Het
Hap1	A	G	11: 100,243,105 (GRCm39)	V174A	probably damaging	Het
Il12rb2	A	G	6: 67,269,300 (GRCm39)	S838P	probably damaging	Het
Ints8	T	C	4: 11,221,150 (GRCm39)	I742V	probably benign	Het
Katnal2	G	T	18: 77,067,707 (GRCm39)	S411R	probably benign	Het
Lrp1	A	C	10: 127,403,300 (GRCm39)	V2091G	probably damaging	Het
Mettl21c	A	T	1: 44,056,368 (GRCm39)	D20E	probably damaging	Het
Mib1	A	T	18: 10,812,077 (GRCm39)	E991D	possibly damaging	Het
Mip	T	C	10: 128,061,772 (GRCm39)	S8P	possibly damaging	Het
Mllt6	T	C	11: 97,568,048 (GRCm39)	S826P	probably damaging	Het
Mlst8	AT	ATT	17: 24,696,987 (GRCm39)		probably null	Het
Myrfl	C	T	10: 116,658,716 (GRCm39)	V414I	probably benign	Het
Nin	T	A	12: 70,077,700 (GRCm39)	Q1035L	probably damaging	Het
Nlgn1	T	A	3: 25,490,464 (GRCm39)	D421V	probably damaging	Het
Nlrp10	A	G	7: 108,523,770 (GRCm39)	V570A	probably benign	Het
Olfm3	A	T	3: 114,895,589 (GRCm39)	E157V	probably null	Het
Or8g24	T	A	9: 38,989,580 (GRCm39)	I154F	probably benign	Het
Or8g37	T	C	9: 39,731,363 (GRCm39)	S143P	probably benign	Het
Otud7a	A	G	7: 63,300,624 (GRCm39)	D21G	probably damaging	Het
Pax2	A	G	19: 44,777,271 (GRCm39)	T155A	probably benign	Het
Pcf11	A	T	7: 92,310,546 (GRCm39)	S481T	probably damaging	Het
Prkab2	T	C	3: 97,573,943 (GRCm39)	V194A	probably benign	Het
Prl3a1	G	A	13: 27,454,136 (GRCm39)	G38E	possibly damaging	Het
Psmb8	T	C	17: 34,419,884 (GRCm39)	V246A	probably damaging	Het
Ptpn12	A	T	5: 21,203,308 (GRCm39)	V490E	probably benign	Het
Ptprm	A	T	17: 67,247,575 (GRCm39)	S587T	probably benign	Het
Qars1	G	A	9: 108,390,380 (GRCm39)	R427H	probably benign	Het
R3hdml	T	C	2: 163,340,216 (GRCm39)	F128L	probably benign	Het
Rapgef4	A	G	2: 72,038,471 (GRCm39)	M541V	probably benign	Het
Rhbdf1	G	A	11: 32,164,277 (GRCm39)	R234*	probably null	Het
Rufy1	A	T	11: 50,297,233 (GRCm39)	D406E	probably benign	Het
Satb1	A	T	17: 52,047,173 (GRCm39)	L683Q	probably damaging	Het
Satb2	T	C	1: 56,938,229 (GRCm39)	T132A	probably damaging	Het
Sbspon	A	G	1: 15,930,519 (GRCm39)	S156P	probably damaging	Het
Shb	A	T	4: 45,458,347 (GRCm39)		probably null	Het
She	A	G	3: 89,756,792 (GRCm39)	K282R	possibly damaging	Het
Slc25a13	A	G	6: 6,152,482 (GRCm39)	L85P	probably damaging	Het
Slc7a13	A	T	4: 19,841,578 (GRCm39)	H475L	probably benign	Het
Sorl1	C	T	9: 41,957,920 (GRCm39)	V575I	probably benign	Het
Spag9	T	A	11: 93,988,184 (GRCm39)	C833S	possibly damaging	Het
Speer2	A	C	16: 69,654,052 (GRCm39)	N232K	probably damaging	Het
Syncrip	A	T	9: 88,358,927 (GRCm39)	M194K	probably damaging	Het
Sytl3	A	C	17: 6,995,732 (GRCm39)	T171P	probably damaging	Het
Taar7f	T	A	10: 23,925,747 (GRCm39)	Y114N	probably damaging	Het
Tamalin	T	C	15: 101,122,381 (GRCm39)	Y67H	probably benign	Het
Tap1	C	G	17: 34,412,481 (GRCm39)	P506R	probably damaging	Het
Tle6	T	C	10: 81,431,319 (GRCm39)	D212G	possibly damaging	Het
Trim80	G	T	11: 115,332,155 (GRCm39)	E116*	probably null	Het
Ttll4	A	G	1: 74,726,718 (GRCm39)	R745G	probably damaging	Het
Vdac2	A	T	14: 21,887,947 (GRCm39)	I85F	possibly damaging	Het
Vmn1r188	A	G	13: 22,272,309 (GRCm39)	R88G	probably damaging	Het
Washc2	T	C	6: 116,232,052 (GRCm39)	S821P	possibly damaging	Het
Wdhd1	T	C	14: 47,507,647 (GRCm39)	Y213C	probably damaging	Het
Wdr55	C	A	18: 36,893,437 (GRCm39)	P33Q	probably damaging	Het
Yrdc	C	T	4: 124,745,739 (GRCm39)	A32V	probably benign	Het
Zfp608	T	A	18: 55,030,851 (GRCm39)	K1030*	probably null	Het
Zfp618	T	A	4: 63,050,555 (GRCm39)		probably null	Het

Other mutations in Nbeal1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Nbeal1	APN	1	60,274,350 (GRCm39)	nonsense	probably null	0.00
IGL00334:Nbeal1	APN	1	60,321,042 (GRCm39)	missense	probably damaging	0.98
IGL00334:Nbeal1	APN	1	60,367,262 (GRCm39)	missense	probably damaging	1.00
IGL00514:Nbeal1	APN	1	60,256,384 (GRCm39)	missense	probably benign	0.31
IGL00596:Nbeal1	APN	1	60,220,900 (GRCm39)	missense	probably damaging	0.96
IGL00654:Nbeal1	APN	1	60,234,170 (GRCm39)	critical splice acceptor site	probably benign	0.00
IGL00757:Nbeal1	APN	1	60,234,302 (GRCm39)	missense	possibly damaging	0.82
IGL00771:Nbeal1	APN	1	60,274,512 (GRCm39)	missense	probably benign	0.11
IGL01315:Nbeal1	APN	1	60,320,500 (GRCm39)	missense	probably damaging	1.00
IGL01445:Nbeal1	APN	1	60,281,784 (GRCm39)	critical splice donor site	probably null
IGL01456:Nbeal1	APN	1	60,269,787 (GRCm39)	missense	probably damaging	1.00
IGL01458:Nbeal1	APN	1	60,281,784 (GRCm39)	critical splice donor site	probably null
IGL01535:Nbeal1	APN	1	60,256,414 (GRCm39)	missense	probably damaging	1.00
IGL01608:Nbeal1	APN	1	60,281,694 (GRCm39)	critical splice acceptor site	probably benign	0.00
IGL02006:Nbeal1	APN	1	60,311,418 (GRCm39)	critical splice donor site	probably null
IGL02105:Nbeal1	APN	1	60,292,660 (GRCm39)	missense	probably damaging	1.00
IGL02409:Nbeal1	APN	1	60,368,494 (GRCm39)	missense	probably benign	0.01
IGL02713:Nbeal1	APN	1	60,274,396 (GRCm39)	missense	possibly damaging	0.94
IGL02720:Nbeal1	APN	1	60,323,146 (GRCm39)	missense	probably damaging	0.98
IGL02887:Nbeal1	APN	1	60,326,603 (GRCm39)	splice site	probably benign
IGL02945:Nbeal1	APN	1	60,245,569 (GRCm39)	missense	probably damaging	1.00
IGL03023:Nbeal1	APN	1	60,292,572 (GRCm39)	missense	probably damaging	0.98
IGL03114:Nbeal1	APN	1	60,317,886 (GRCm39)	missense	probably damaging	1.00
IGL03231:Nbeal1	APN	1	60,275,618 (GRCm39)	missense	probably benign	0.44
IGL03241:Nbeal1	APN	1	60,274,027 (GRCm39)	missense	possibly damaging	0.46
IGL03241:Nbeal1	APN	1	60,274,028 (GRCm39)	missense	probably benign	0.44
IGL03382:Nbeal1	APN	1	60,300,745 (GRCm39)	critical splice donor site	probably null
IGL03412:Nbeal1	APN	1	60,281,726 (GRCm39)	nonsense	probably null
coach	UTSW	1	60,292,640 (GRCm39)	nonsense	probably null
Committee	UTSW	1	60,332,062 (GRCm39)	missense	probably damaging	1.00
Disgrace	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
Dravrah	UTSW	1	60,323,251 (GRCm39)	missense	probably damaging	1.00
Harvard	UTSW	1	60,274,722 (GRCm39)	splice site	probably null
horrified	UTSW	1	60,283,983 (GRCm39)	missense	probably damaging	1.00
Lampoon	UTSW	1	60,300,745 (GRCm39)	critical splice donor site	probably null
lawyer	UTSW	1	60,349,383 (GRCm39)	nonsense	probably null
magistrate	UTSW	1	60,233,756 (GRCm39)	critical splice donor site	probably null
Maratimus	UTSW	1	60,331,047 (GRCm39)	missense	probably damaging	1.00
National	UTSW	1	60,261,422 (GRCm39)	missense	possibly damaging	0.95
phainopepla	UTSW	1	60,358,846 (GRCm39)	missense	probably damaging	1.00
R3875_Nbeal1_770	UTSW	1	60,233,758 (GRCm39)	splice site	probably benign
satirical	UTSW	1	60,274,721 (GRCm39)	critical splice donor site	probably null
silky	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
stiggs	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
3-1:Nbeal1	UTSW	1	60,303,431 (GRCm39)	splice site	probably benign
P0007:Nbeal1	UTSW	1	60,358,847 (GRCm39)	missense	probably damaging	0.98
P0028:Nbeal1	UTSW	1	60,331,096 (GRCm39)	missense	probably damaging	1.00
R0041:Nbeal1	UTSW	1	60,321,030 (GRCm39)	missense	probably benign	0.05
R0051:Nbeal1	UTSW	1	60,349,422 (GRCm39)	missense	probably benign	0.19
R0052:Nbeal1	UTSW	1	60,267,771 (GRCm39)	splice site	probably benign
R0054:Nbeal1	UTSW	1	60,326,560 (GRCm39)	utr 3 prime	probably benign
R0062:Nbeal1	UTSW	1	60,286,876 (GRCm39)	missense	probably benign	0.01
R0062:Nbeal1	UTSW	1	60,286,876 (GRCm39)	missense	probably benign	0.01
R0094:Nbeal1	UTSW	1	60,344,468 (GRCm39)	missense	possibly damaging	0.62
R0310:Nbeal1	UTSW	1	60,344,529 (GRCm39)	splice site	probably benign
R0324:Nbeal1	UTSW	1	60,332,032 (GRCm39)	missense	probably damaging	1.00
R0329:Nbeal1	UTSW	1	60,307,222 (GRCm39)	missense	probably damaging	1.00
R0330:Nbeal1	UTSW	1	60,307,222 (GRCm39)	missense	probably damaging	1.00
R0417:Nbeal1	UTSW	1	60,286,893 (GRCm39)	missense	probably benign	0.00
R0421:Nbeal1	UTSW	1	60,307,598 (GRCm39)	missense	probably benign	0.08
R0617:Nbeal1	UTSW	1	60,320,991 (GRCm39)	nonsense	probably null
R1034:Nbeal1	UTSW	1	60,329,165 (GRCm39)	nonsense	probably null
R1082:Nbeal1	UTSW	1	60,351,385 (GRCm39)	missense	probably damaging	0.99
R1123:Nbeal1	UTSW	1	60,299,428 (GRCm39)	missense	probably benign
R1187:Nbeal1	UTSW	1	60,233,687 (GRCm39)	missense	probably damaging	1.00
R1484:Nbeal1	UTSW	1	60,240,098 (GRCm39)	missense	probably damaging	1.00
R1594:Nbeal1	UTSW	1	60,344,450 (GRCm39)	missense	possibly damaging	0.91
R1651:Nbeal1	UTSW	1	60,239,278 (GRCm39)	missense	probably damaging	1.00
R1678:Nbeal1	UTSW	1	60,299,493 (GRCm39)	missense	probably benign	0.00
R1806:Nbeal1	UTSW	1	60,323,251 (GRCm39)	missense	probably damaging	1.00
R1937:Nbeal1	UTSW	1	60,307,100 (GRCm39)	nonsense	probably null
R1953:Nbeal1	UTSW	1	60,273,999 (GRCm39)	missense	probably damaging	1.00
R2038:Nbeal1	UTSW	1	60,245,503 (GRCm39)	missense	probably benign	0.00
R2044:Nbeal1	UTSW	1	60,358,846 (GRCm39)	missense	probably damaging	1.00
R2050:Nbeal1	UTSW	1	60,332,123 (GRCm39)	splice site	probably null
R2055:Nbeal1	UTSW	1	60,350,216 (GRCm39)	missense	probably damaging	1.00
R2064:Nbeal1	UTSW	1	60,309,515 (GRCm39)	missense	possibly damaging	0.89
R2100:Nbeal1	UTSW	1	60,344,430 (GRCm39)	splice site	probably null
R2181:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R2192:Nbeal1	UTSW	1	60,321,054 (GRCm39)	missense	probably damaging	1.00
R2203:Nbeal1	UTSW	1	60,323,165 (GRCm39)	missense	probably benign	0.21
R2267:Nbeal1	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
R2268:Nbeal1	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
R2351:Nbeal1	UTSW	1	60,276,257 (GRCm39)	missense	possibly damaging	0.90
R2366:Nbeal1	UTSW	1	60,290,511 (GRCm39)	missense	probably damaging	0.97
R2393:Nbeal1	UTSW	1	60,290,529 (GRCm39)	missense	probably damaging	0.98
R3545:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3546:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3547:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3701:Nbeal1	UTSW	1	60,290,572 (GRCm39)	splice site	probably benign
R3747:Nbeal1	UTSW	1	60,234,182 (GRCm39)	missense	probably damaging	0.98
R3875:Nbeal1	UTSW	1	60,233,758 (GRCm39)	splice site	probably benign
R4119:Nbeal1	UTSW	1	60,331,029 (GRCm39)	missense	probably damaging	0.99
R4256:Nbeal1	UTSW	1	60,370,107 (GRCm39)	missense	probably benign	0.19
R4371:Nbeal1	UTSW	1	60,329,105 (GRCm39)	missense	possibly damaging	0.95
R4450:Nbeal1	UTSW	1	60,306,933 (GRCm39)	missense	probably damaging	0.97
R4558:Nbeal1	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
R4618:Nbeal1	UTSW	1	60,267,890 (GRCm39)	intron	probably benign
R4673:Nbeal1	UTSW	1	60,368,549 (GRCm39)	missense	probably damaging	1.00
R4719:Nbeal1	UTSW	1	60,274,722 (GRCm39)	splice site	probably null
R4798:Nbeal1	UTSW	1	60,261,352 (GRCm39)	splice site	probably null
R4826:Nbeal1	UTSW	1	60,290,501 (GRCm39)	missense	possibly damaging	0.79
R4841:Nbeal1	UTSW	1	60,292,534 (GRCm39)	missense	probably damaging	1.00
R4842:Nbeal1	UTSW	1	60,292,534 (GRCm39)	missense	probably damaging	1.00
R4895:Nbeal1	UTSW	1	60,332,062 (GRCm39)	missense	probably damaging	1.00
R4929:Nbeal1	UTSW	1	60,277,813 (GRCm39)	missense	probably damaging	1.00
R5026:Nbeal1	UTSW	1	60,276,338 (GRCm39)	missense	probably damaging	1.00
R5243:Nbeal1	UTSW	1	60,309,487 (GRCm39)	missense	probably damaging	0.99
R5300:Nbeal1	UTSW	1	60,274,718 (GRCm39)	nonsense	probably null
R5345:Nbeal1	UTSW	1	60,367,369 (GRCm39)	critical splice donor site	probably null
R5502:Nbeal1	UTSW	1	60,350,158 (GRCm39)	missense	probably damaging	1.00
R5542:Nbeal1	UTSW	1	60,316,353 (GRCm39)	missense	probably benign	0.00
R5555:Nbeal1	UTSW	1	60,276,311 (GRCm39)	missense	possibly damaging	0.93
R5580:Nbeal1	UTSW	1	60,281,761 (GRCm39)	missense	probably benign	0.45
R5765:Nbeal1	UTSW	1	60,331,006 (GRCm39)	missense	probably damaging	1.00
R5802:Nbeal1	UTSW	1	60,311,380 (GRCm39)	missense	probably benign	0.01
R5907:Nbeal1	UTSW	1	60,267,950 (GRCm39)	intron	probably benign
R5918:Nbeal1	UTSW	1	60,307,051 (GRCm39)	missense	possibly damaging	0.90
R5923:Nbeal1	UTSW	1	60,287,554 (GRCm39)	missense	probably damaging	1.00
R6066:Nbeal1	UTSW	1	60,287,564 (GRCm39)	missense	probably benign	0.29
R6091:Nbeal1	UTSW	1	60,220,715 (GRCm39)	start gained	probably benign
R6113:Nbeal1	UTSW	1	60,261,422 (GRCm39)	missense	possibly damaging	0.95
R6143:Nbeal1	UTSW	1	60,290,466 (GRCm39)	missense	possibly damaging	0.81
R6194:Nbeal1	UTSW	1	60,296,643 (GRCm39)	missense	possibly damaging	0.80
R6197:Nbeal1	UTSW	1	60,261,287 (GRCm39)	missense	probably damaging	0.99
R6228:Nbeal1	UTSW	1	60,335,083 (GRCm39)	missense	probably benign	0.00
R6229:Nbeal1	UTSW	1	60,287,524 (GRCm39)	missense	possibly damaging	0.88
R6309:Nbeal1	UTSW	1	60,277,878 (GRCm39)	missense	probably benign
R6457:Nbeal1	UTSW	1	60,292,633 (GRCm39)	missense	probably benign	0.31
R6489:Nbeal1	UTSW	1	60,370,101 (GRCm39)	missense	possibly damaging	0.89
R6845:Nbeal1	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
R7021:Nbeal1	UTSW	1	60,300,745 (GRCm39)	critical splice donor site	probably null
R7033:Nbeal1	UTSW	1	60,350,106 (GRCm39)	missense	probably damaging	1.00
R7144:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7145:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7146:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7157:Nbeal1	UTSW	1	60,299,793 (GRCm39)	nonsense	probably null
R7157:Nbeal1	UTSW	1	60,276,317 (GRCm39)	missense	probably damaging	1.00
R7209:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7210:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7211:Nbeal1	UTSW	1	60,240,110 (GRCm39)	missense	probably damaging	1.00
R7212:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7213:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7214:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7283:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7285:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7287:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7296:Nbeal1	UTSW	1	60,349,383 (GRCm39)	nonsense	probably null
R7312:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7313:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7329:Nbeal1	UTSW	1	60,256,355 (GRCm39)	missense	probably benign	0.39
R7380:Nbeal1	UTSW	1	60,283,969 (GRCm39)	missense	probably damaging	1.00
R7414:Nbeal1	UTSW	1	60,233,756 (GRCm39)	critical splice donor site	probably null
R7477:Nbeal1	UTSW	1	60,300,743 (GRCm39)	missense	probably benign
R7507:Nbeal1	UTSW	1	60,274,626 (GRCm39)	missense	probably damaging	1.00
R7642:Nbeal1	UTSW	1	60,316,386 (GRCm39)	missense	probably benign	0.31
R7678:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7689:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7728:Nbeal1	UTSW	1	60,283,983 (GRCm39)	missense	probably damaging	1.00
R7757:Nbeal1	UTSW	1	60,296,609 (GRCm39)	missense	probably damaging	0.97
R7761:Nbeal1	UTSW	1	60,358,500 (GRCm39)	missense	probably benign	0.00
R7813:Nbeal1	UTSW	1	60,331,048 (GRCm39)	missense	probably damaging	1.00
R7829:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7891:Nbeal1	UTSW	1	60,299,591 (GRCm39)	missense	probably benign
R7902:Nbeal1	UTSW	1	60,331,029 (GRCm39)	missense	probably damaging	0.99
R8022:Nbeal1	UTSW	1	60,299,431 (GRCm39)	nonsense	probably null
R8053:Nbeal1	UTSW	1	60,318,954 (GRCm39)	missense	probably damaging	0.98
R8169:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8170:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8178:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8182:Nbeal1	UTSW	1	60,239,292 (GRCm39)	missense	probably benign	0.00
R8186:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8187:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8193:Nbeal1	UTSW	1	60,292,640 (GRCm39)	nonsense	probably null
R8209:Nbeal1	UTSW	1	60,316,336 (GRCm39)	missense	probably damaging	0.99
R8226:Nbeal1	UTSW	1	60,316,336 (GRCm39)	missense	probably damaging	0.99
R8549:Nbeal1	UTSW	1	60,274,721 (GRCm39)	critical splice donor site	probably null
R8560:Nbeal1	UTSW	1	60,274,316 (GRCm39)	missense	probably benign	0.38
R8753:Nbeal1	UTSW	1	60,307,542 (GRCm39)	missense	probably damaging	1.00
R8769:Nbeal1	UTSW	1	60,274,370 (GRCm39)	missense	probably damaging	0.99
R8771:Nbeal1	UTSW	1	60,300,743 (GRCm39)	missense	probably benign
R8952:Nbeal1	UTSW	1	60,299,459 (GRCm39)	missense	probably benign	0.01
R9014:Nbeal1	UTSW	1	60,329,118 (GRCm39)	missense	probably damaging	1.00
R9056:Nbeal1	UTSW	1	60,317,885 (GRCm39)	missense	probably damaging	1.00
R9091:Nbeal1	UTSW	1	60,307,548 (GRCm39)	missense	possibly damaging	0.50
R9138:Nbeal1	UTSW	1	60,286,904 (GRCm39)	nonsense	probably null
R9168:Nbeal1	UTSW	1	60,331,047 (GRCm39)	missense	probably damaging	1.00
R9200:Nbeal1	UTSW	1	60,320,425 (GRCm39)	missense	probably damaging	1.00
R9205:Nbeal1	UTSW	1	60,317,839 (GRCm39)	missense	probably damaging	1.00
R9270:Nbeal1	UTSW	1	60,307,548 (GRCm39)	missense	possibly damaging	0.50
R9322:Nbeal1	UTSW	1	60,297,818 (GRCm39)	missense	possibly damaging	0.91
R9405:Nbeal1	UTSW	1	60,349,424 (GRCm39)	missense	probably damaging	1.00
R9554:Nbeal1	UTSW	1	60,290,287 (GRCm39)	nonsense	probably null
R9557:Nbeal1	UTSW	1	60,274,509 (GRCm39)	missense	probably benign
R9560:Nbeal1	UTSW	1	60,368,544 (GRCm39)	missense	probably damaging	1.00
R9641:Nbeal1	UTSW	1	60,350,247 (GRCm39)	missense	probably damaging	1.00
R9784:Nbeal1	UTSW	1	60,299,741 (GRCm39)	nonsense	probably null
X0022:Nbeal1	UTSW	1	60,316,391 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- TAGCATAGAAAGCCCCTGTTAC -3'
(R):5'- GCCAACTGAAGTGTGATCACC -3'

Sequencing Primer
(F):5'- AGCCCCTGTTACAAAAGAGAG -3'
(R):5'- TGAAGTGTGATCACCCTCAACAG -3'

Posted On

2014-08-01