Incidental Mutation 'R4669:Phf3'
| ID |
352215 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phf3
|
| Ensembl Gene |
ENSMUSG00000048874 |
| Gene Name |
PHD finger protein 3 |
| Synonyms |
AU020177, 2310061N19Rik |
| MMRRC Submission |
041925-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4669 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
30841417-30912989 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 30869027 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 674
(T674A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000139610
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000088310]
[ENSMUST00000186733]
[ENSMUST00000188780]
[ENSMUST00000191064]
|
| AlphaFold |
B2RQG2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000088310
AA Change: T674A
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000085650
Gene: ENSMUSG00000048874
AA Change: T674A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
337 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
660 |
N/A |
INTRINSIC |
|
PHD
|
697 |
748 |
3.82e-10 |
SMART |
|
low complexity region
|
847 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
876 |
887 |
N/A |
INTRINSIC |
|
TFS2M
|
908 |
1008 |
1.28e-47 |
SMART |
|
Pfam:SPOC
|
1188 |
1294 |
4.2e-26 |
PFAM |
|
low complexity region
|
1367 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1516 |
1529 |
N/A |
INTRINSIC |
|
low complexity region
|
1597 |
1620 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1811 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1846 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185521
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000186105
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000186733
AA Change: T674A
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000139610
Gene: ENSMUSG00000048874
AA Change: T674A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
337 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
660 |
N/A |
INTRINSIC |
|
PHD
|
697 |
748 |
3.82e-10 |
SMART |
|
low complexity region
|
847 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
876 |
887 |
N/A |
INTRINSIC |
|
TFS2M
|
908 |
1008 |
1.28e-47 |
SMART |
|
Pfam:SPOC
|
1188 |
1294 |
4.2e-26 |
PFAM |
|
low complexity region
|
1367 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1516 |
1529 |
N/A |
INTRINSIC |
|
low complexity region
|
1597 |
1620 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1811 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1846 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000187600
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000188780
|
| SMART Domains |
Protein: ENSMUSP00000140935
Gene: ENSMUSG00000048874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
158 |
169 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191064
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195437
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000191245
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acad8 |
A |
G |
9: 26,901,923 (GRCm39) |
L147P |
probably damaging |
Het |
| Acan |
A |
G |
7: 78,750,890 (GRCm39) |
E464G |
probably benign |
Het |
| Agap1 |
A |
G |
1: 89,765,528 (GRCm39) |
|
probably null |
Het |
| Akap13 |
A |
G |
7: 75,378,842 (GRCm39) |
T2128A |
probably damaging |
Het |
| Ap2a1 |
A |
T |
7: 44,552,343 (GRCm39) |
|
probably benign |
Het |
| Arap3 |
T |
C |
18: 38,129,307 (GRCm39) |
D217G |
probably benign |
Het |
| Arl2 |
C |
A |
19: 6,184,716 (GRCm39) |
R179L |
probably damaging |
Het |
| Atg2a |
T |
A |
19: 6,309,017 (GRCm39) |
|
probably null |
Het |
| B3gat1 |
T |
A |
9: 26,663,052 (GRCm39) |
L6Q |
probably benign |
Het |
| Bcl10 |
A |
G |
3: 145,636,327 (GRCm39) |
N75S |
probably damaging |
Het |
| Bmpr2 |
T |
C |
1: 59,906,875 (GRCm39) |
L656S |
probably damaging |
Het |
| Brms1l |
A |
G |
12: 55,888,356 (GRCm39) |
E48G |
possibly damaging |
Het |
| C2cd2l |
A |
T |
9: 44,226,322 (GRCm39) |
N414K |
possibly damaging |
Het |
| Capn2 |
C |
T |
1: 182,298,345 (GRCm39) |
C640Y |
probably benign |
Het |
| Ccdc153 |
G |
T |
9: 44,157,021 (GRCm39) |
R99M |
probably damaging |
Het |
| Ccdc51 |
A |
G |
9: 108,920,030 (GRCm39) |
N142S |
probably benign |
Het |
| Cdipt |
A |
G |
7: 126,577,578 (GRCm39) |
H108R |
possibly damaging |
Het |
| Ceacam20 |
T |
C |
7: 19,719,952 (GRCm39) |
Y495H |
probably damaging |
Het |
| Celf2 |
T |
C |
2: 6,726,339 (GRCm39) |
I47V |
probably benign |
Het |
| Cts3 |
C |
T |
13: 61,714,637 (GRCm39) |
E223K |
probably benign |
Het |
| Cyp2a22 |
T |
C |
7: 26,637,280 (GRCm39) |
D168G |
possibly damaging |
Het |
| Cyp2c67 |
T |
A |
19: 39,632,098 (GRCm39) |
H90L |
probably benign |
Het |
| Ddx4 |
T |
C |
13: 112,758,778 (GRCm39) |
Y261C |
probably damaging |
Het |
| Dnah17 |
T |
C |
11: 117,965,119 (GRCm39) |
T2308A |
probably benign |
Het |
| Dnah6 |
T |
C |
6: 73,014,671 (GRCm39) |
T3587A |
probably damaging |
Het |
| Dpy19l1 |
C |
T |
9: 24,343,664 (GRCm39) |
V494I |
possibly damaging |
Het |
| Dse |
T |
G |
10: 34,029,008 (GRCm39) |
Y694S |
probably damaging |
Het |
| Emilin3 |
T |
C |
2: 160,752,717 (GRCm39) |
I78V |
probably benign |
Het |
| Esam |
T |
A |
9: 37,447,952 (GRCm39) |
Y195* |
probably null |
Het |
| Extl3 |
T |
A |
14: 65,313,745 (GRCm39) |
N479I |
possibly damaging |
Het |
| Fat2 |
A |
G |
11: 55,202,441 (GRCm39) |
V211A |
probably benign |
Het |
| Ganc |
G |
T |
2: 120,261,548 (GRCm39) |
V343F |
probably benign |
Het |
| Ggt5 |
T |
C |
10: 75,438,865 (GRCm39) |
L121P |
probably damaging |
Het |
| Gnmt |
A |
T |
17: 47,037,225 (GRCm39) |
C186* |
probably null |
Het |
| Gpr75 |
A |
T |
11: 30,842,072 (GRCm39) |
I326F |
probably damaging |
Het |
| Gsdme |
C |
T |
6: 50,185,102 (GRCm39) |
V451M |
probably damaging |
Het |
| H2-T23 |
G |
T |
17: 36,342,690 (GRCm39) |
D149E |
probably damaging |
Het |
| Hmcn2 |
G |
T |
2: 31,325,804 (GRCm39) |
R4277L |
probably benign |
Het |
| Irf9 |
C |
A |
14: 55,843,223 (GRCm39) |
H94N |
probably benign |
Het |
| Jhy |
T |
C |
9: 40,872,449 (GRCm39) |
N20S |
probably benign |
Het |
| Klf17 |
C |
A |
4: 117,617,568 (GRCm39) |
C263F |
probably damaging |
Het |
| Lama5 |
T |
C |
2: 179,822,430 (GRCm39) |
Y2881C |
probably damaging |
Het |
| Lig1 |
T |
G |
7: 13,044,953 (GRCm39) |
I882S |
probably damaging |
Het |
| Ltn1 |
A |
T |
16: 87,215,375 (GRCm39) |
M420K |
possibly damaging |
Het |
| Mael |
T |
C |
1: 166,063,077 (GRCm39) |
E125G |
probably damaging |
Het |
| Mib2 |
C |
T |
4: 155,741,872 (GRCm39) |
D275N |
possibly damaging |
Het |
| Mical3 |
C |
T |
6: 120,934,664 (GRCm39) |
R1805Q |
probably damaging |
Het |
| Mix23 |
A |
G |
16: 35,903,089 (GRCm39) |
D27G |
probably damaging |
Het |
| Mllt10 |
A |
G |
2: 18,208,444 (GRCm39) |
D158G |
probably damaging |
Het |
| Mocs1 |
A |
G |
17: 49,761,613 (GRCm39) |
D569G |
possibly damaging |
Het |
| Msh6 |
T |
C |
17: 88,292,234 (GRCm39) |
S330P |
possibly damaging |
Het |
| Mtmr2 |
T |
C |
9: 13,707,260 (GRCm39) |
S199P |
probably damaging |
Het |
| Ndufaf5 |
T |
C |
2: 140,029,675 (GRCm39) |
V164A |
probably benign |
Het |
| Nek9 |
T |
C |
12: 85,360,978 (GRCm39) |
E518G |
probably benign |
Het |
| Nfatc2 |
T |
C |
2: 168,413,410 (GRCm39) |
I72V |
probably benign |
Het |
| Nlrp9c |
C |
T |
7: 26,074,793 (GRCm39) |
A746T |
possibly damaging |
Het |
| Nup42 |
A |
G |
5: 24,387,415 (GRCm39) |
R402G |
probably benign |
Het |
| Ogdh |
G |
T |
11: 6,290,600 (GRCm39) |
C406F |
probably benign |
Het |
| Or3a1d |
A |
G |
11: 74,237,789 (GRCm39) |
V207A |
probably benign |
Het |
| Or4c120 |
G |
A |
2: 89,001,245 (GRCm39) |
H104Y |
probably damaging |
Het |
| Or8b35 |
A |
T |
9: 37,904,381 (GRCm39) |
I198F |
possibly damaging |
Het |
| Or8g17 |
T |
A |
9: 38,930,675 (GRCm39) |
Y54F |
probably benign |
Het |
| Or8j3 |
A |
T |
2: 86,028,277 (GRCm39) |
M273K |
possibly damaging |
Het |
| Otof |
A |
G |
5: 30,578,318 (GRCm39) |
|
probably null |
Het |
| Pcdhb17 |
T |
C |
18: 37,619,259 (GRCm39) |
S350P |
probably damaging |
Het |
| Pikfyve |
T |
A |
1: 65,289,432 (GRCm39) |
C1235S |
probably damaging |
Het |
| Ppfia3 |
T |
C |
7: 45,001,517 (GRCm39) |
E465G |
probably damaging |
Het |
| Prkg1 |
T |
A |
19: 31,641,639 (GRCm39) |
I15F |
probably damaging |
Het |
| Rab5c |
A |
G |
11: 100,610,843 (GRCm39) |
F22L |
probably damaging |
Het |
| Raf1 |
A |
G |
6: 115,609,880 (GRCm39) |
S220P |
probably damaging |
Het |
| Rgl1 |
T |
G |
1: 152,397,122 (GRCm39) |
R716S |
probably damaging |
Het |
| Rhbg |
C |
A |
3: 88,153,273 (GRCm39) |
W205L |
probably damaging |
Het |
| Rimbp3 |
A |
G |
16: 17,027,053 (GRCm39) |
E159G |
possibly damaging |
Het |
| Ryr1 |
T |
C |
7: 28,759,256 (GRCm39) |
D3338G |
probably null |
Het |
| Sash1 |
T |
C |
10: 8,606,149 (GRCm39) |
N747S |
probably benign |
Het |
| Serpina3g |
A |
T |
12: 104,205,479 (GRCm39) |
I73F |
probably damaging |
Het |
| Sfxn2 |
C |
A |
19: 46,574,213 (GRCm39) |
N134K |
probably damaging |
Het |
| Slc12a6 |
A |
G |
2: 112,184,640 (GRCm39) |
H853R |
probably damaging |
Het |
| Slc16a12 |
C |
T |
19: 34,649,965 (GRCm39) |
D357N |
probably damaging |
Het |
| Slc39a8 |
T |
C |
3: 135,561,772 (GRCm39) |
Y164H |
probably benign |
Het |
| Snx9 |
A |
G |
17: 5,977,499 (GRCm39) |
K518E |
probably damaging |
Het |
| Spdye4c |
G |
A |
2: 128,434,273 (GRCm39) |
V5I |
possibly damaging |
Het |
| Spef2 |
A |
G |
15: 9,676,459 (GRCm39) |
V704A |
probably benign |
Het |
| Stard3nl |
T |
A |
13: 19,560,689 (GRCm39) |
N29Y |
probably damaging |
Het |
| Strap |
C |
A |
6: 137,712,384 (GRCm39) |
S11* |
probably null |
Het |
| Synpo2 |
A |
G |
3: 122,906,712 (GRCm39) |
L868P |
probably damaging |
Het |
| Tenm2 |
A |
G |
11: 35,901,314 (GRCm39) |
V2474A |
probably damaging |
Het |
| Tm9sf4 |
T |
A |
2: 153,029,228 (GRCm39) |
V92D |
probably damaging |
Het |
| Tmf1 |
A |
T |
6: 97,147,388 (GRCm39) |
M526K |
probably benign |
Het |
| Top2b |
T |
G |
14: 16,409,189 (GRCm38) |
I777M |
probably damaging |
Het |
| Ttc39d |
A |
G |
17: 80,525,068 (GRCm39) |
I576V |
probably benign |
Het |
| Upk1a |
T |
G |
7: 30,304,554 (GRCm39) |
T193P |
probably benign |
Het |
| Vmn2r67 |
A |
T |
7: 84,799,732 (GRCm39) |
V502E |
probably benign |
Het |
| Wdr17 |
A |
G |
8: 55,143,083 (GRCm39) |
V189A |
possibly damaging |
Het |
| Wrap73 |
A |
T |
4: 154,236,153 (GRCm39) |
S161C |
probably benign |
Het |
| Zfp568 |
A |
G |
7: 29,722,702 (GRCm39) |
H549R |
probably damaging |
Het |
| Zfp605 |
T |
A |
5: 110,275,227 (GRCm39) |
M115K |
possibly damaging |
Het |
| Zp1 |
T |
A |
19: 10,896,269 (GRCm39) |
H152L |
probably benign |
Het |
|
| Other mutations in Phf3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00234:Phf3
|
APN |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00704:Phf3
|
APN |
1 |
30,843,919 (GRCm39) |
missense |
probably benign |
|
|
IGL01147:Phf3
|
APN |
1 |
30,843,250 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01360:Phf3
|
APN |
1 |
30,847,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01376:Phf3
|
APN |
1 |
30,869,566 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL01396:Phf3
|
APN |
1 |
30,843,386 (GRCm39) |
nonsense |
probably null |
|
|
IGL01830:Phf3
|
APN |
1 |
30,853,148 (GRCm39) |
nonsense |
probably null |
|
|
IGL02108:Phf3
|
APN |
1 |
30,869,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02156:Phf3
|
APN |
1 |
30,847,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02576:Phf3
|
APN |
1 |
30,869,117 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03031:Phf3
|
APN |
1 |
30,843,734 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03334:Phf3
|
APN |
1 |
30,844,810 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03411:Phf3
|
APN |
1 |
30,843,482 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4976:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
utr 3 prime |
probably benign |
|
|
PIT4458001:Phf3
|
UTSW |
1 |
30,855,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0037:Phf3
|
UTSW |
1 |
30,843,999 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0052:Phf3
|
UTSW |
1 |
30,847,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0114:Phf3
|
UTSW |
1 |
30,844,524 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0123:Phf3
|
UTSW |
1 |
30,844,146 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0225:Phf3
|
UTSW |
1 |
30,844,146 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0715:Phf3
|
UTSW |
1 |
30,850,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0835:Phf3
|
UTSW |
1 |
30,869,632 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0848:Phf3
|
UTSW |
1 |
30,902,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Phf3
|
UTSW |
1 |
30,845,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1522:Phf3
|
UTSW |
1 |
30,844,729 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1549:Phf3
|
UTSW |
1 |
30,843,923 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1555:Phf3
|
UTSW |
1 |
30,844,958 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1780:Phf3
|
UTSW |
1 |
30,851,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Phf3
|
UTSW |
1 |
30,845,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Phf3
|
UTSW |
1 |
30,869,704 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1912:Phf3
|
UTSW |
1 |
30,843,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1957:Phf3
|
UTSW |
1 |
30,870,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2019:Phf3
|
UTSW |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2259:Phf3
|
UTSW |
1 |
30,843,424 (GRCm39) |
missense |
probably benign |
0.20 |
|
R2305:Phf3
|
UTSW |
1 |
30,844,556 (GRCm39) |
nonsense |
probably null |
|
|
R2345:Phf3
|
UTSW |
1 |
30,844,432 (GRCm39) |
nonsense |
probably null |
|
|
R2424:Phf3
|
UTSW |
1 |
30,845,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2497:Phf3
|
UTSW |
1 |
30,869,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Phf3
|
UTSW |
1 |
30,849,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3522:Phf3
|
UTSW |
1 |
30,844,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3816:Phf3
|
UTSW |
1 |
30,844,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4152:Phf3
|
UTSW |
1 |
30,870,539 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4403:Phf3
|
UTSW |
1 |
30,843,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4658:Phf3
|
UTSW |
1 |
30,902,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4663:Phf3
|
UTSW |
1 |
30,860,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4706:Phf3
|
UTSW |
1 |
30,844,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4757:Phf3
|
UTSW |
1 |
30,859,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4766:Phf3
|
UTSW |
1 |
30,853,020 (GRCm39) |
unclassified |
probably benign |
|
|
R4786:Phf3
|
UTSW |
1 |
30,855,638 (GRCm39) |
nonsense |
probably null |
|
|
R5107:Phf3
|
UTSW |
1 |
30,870,566 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5155:Phf3
|
UTSW |
1 |
30,863,457 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R5310:Phf3
|
UTSW |
1 |
30,842,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5823:Phf3
|
UTSW |
1 |
30,843,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5944:Phf3
|
UTSW |
1 |
30,859,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5979:Phf3
|
UTSW |
1 |
30,844,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6007:Phf3
|
UTSW |
1 |
30,843,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Phf3
|
UTSW |
1 |
30,902,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6072:Phf3
|
UTSW |
1 |
30,869,769 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6533:Phf3
|
UTSW |
1 |
30,845,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6649:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6653:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6852:Phf3
|
UTSW |
1 |
30,843,711 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6855:Phf3
|
UTSW |
1 |
30,859,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6862:Phf3
|
UTSW |
1 |
30,853,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6930:Phf3
|
UTSW |
1 |
30,850,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7135:Phf3
|
UTSW |
1 |
30,870,190 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7323:Phf3
|
UTSW |
1 |
30,852,211 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7352:Phf3
|
UTSW |
1 |
30,843,407 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7455:Phf3
|
UTSW |
1 |
30,876,239 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7549:Phf3
|
UTSW |
1 |
30,870,556 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7609:Phf3
|
UTSW |
1 |
30,844,582 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7720:Phf3
|
UTSW |
1 |
30,868,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7745:Phf3
|
UTSW |
1 |
30,843,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8134:Phf3
|
UTSW |
1 |
30,863,552 (GRCm39) |
missense |
unknown |
|
|
R8264:Phf3
|
UTSW |
1 |
30,870,138 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8545:Phf3
|
UTSW |
1 |
30,863,391 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8821:Phf3
|
UTSW |
1 |
30,860,347 (GRCm39) |
nonsense |
probably null |
|
|
R8831:Phf3
|
UTSW |
1 |
30,860,347 (GRCm39) |
nonsense |
probably null |
|
|
R8873:Phf3
|
UTSW |
1 |
30,843,773 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R9101:Phf3
|
UTSW |
1 |
30,843,026 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9402:Phf3
|
UTSW |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9426:Phf3
|
UTSW |
1 |
30,870,625 (GRCm39) |
nonsense |
probably null |
|
|
R9594:Phf3
|
UTSW |
1 |
30,869,003 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9707:Phf3
|
UTSW |
1 |
30,868,923 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9803:Phf3
|
UTSW |
1 |
30,869,872 (GRCm39) |
missense |
probably benign |
0.16 |
|
Z1177:Phf3
|
UTSW |
1 |
30,851,049 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Phf3
|
UTSW |
1 |
30,844,132 (GRCm39) |
missense |
unknown |
|
|
Z1177:Phf3
|
UTSW |
1 |
30,843,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCACAGATCCCAATCCTCATTCTAG -3'
(R):5'- ACACTTGGTGCATTCCAGTC -3'
Sequencing Primer
(F):5'- TCTAGAAGTTTCCCAATGTACACAC -3'
(R):5'- CTTGGTGCATTCCAGTCAAAAACAG -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation