Incidental Mutation 'R5338:Mprip'
| ID |
423647 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mprip
|
| Ensembl Gene |
ENSMUSG00000005417 |
| Gene Name |
myosin phosphatase Rho interacting protein |
| Synonyms |
p116 Rho interacting protein, p116Rip, Gm34094, RIP3, Rhoip3 |
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.669)
|
| Stock # |
R5338 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
59552973-59671686 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 59651399 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 1701
(Y1701C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071081
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066330]
[ENSMUST00000072031]
[ENSMUST00000108751]
[ENSMUST00000116371]
[ENSMUST00000133861]
|
| AlphaFold |
P97434 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066330
AA Change: Y1701C
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000071081
Gene: ENSMUSG00000005417
AA Change: Y1701C
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
44 |
152 |
3.33e-10 |
SMART |
|
low complexity region
|
179 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
221 |
234 |
N/A |
INTRINSIC |
|
Blast:PH
|
249 |
320 |
1e-10 |
BLAST |
|
PH
|
351 |
448 |
3.76e-18 |
SMART |
|
low complexity region
|
492 |
501 |
N/A |
INTRINSIC |
|
low complexity region
|
536 |
555 |
N/A |
INTRINSIC |
|
coiled coil region
|
636 |
671 |
N/A |
INTRINSIC |
|
Blast:PAC
|
806 |
848 |
2e-10 |
BLAST |
|
low complexity region
|
1005 |
1023 |
N/A |
INTRINSIC |
|
low complexity region
|
1047 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1114 |
1128 |
N/A |
INTRINSIC |
|
low complexity region
|
1183 |
1200 |
N/A |
INTRINSIC |
|
coiled coil region
|
1267 |
1300 |
N/A |
INTRINSIC |
|
coiled coil region
|
1617 |
1642 |
N/A |
INTRINSIC |
|
coiled coil region
|
1729 |
1779 |
N/A |
INTRINSIC |
|
coiled coil region
|
1899 |
1936 |
N/A |
INTRINSIC |
|
coiled coil region
|
1960 |
2110 |
N/A |
INTRINSIC |
|
coiled coil region
|
2132 |
2206 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000072031
|
| SMART Domains |
Protein: ENSMUSP00000071914
Gene: ENSMUSG00000005417
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
44 |
152 |
3.33e-10 |
SMART |
|
low complexity region
|
179 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
221 |
234 |
N/A |
INTRINSIC |
|
Blast:PH
|
254 |
320 |
1e-10 |
BLAST |
|
PH
|
387 |
484 |
3.76e-18 |
SMART |
|
low complexity region
|
528 |
537 |
N/A |
INTRINSIC |
|
low complexity region
|
572 |
591 |
N/A |
INTRINSIC |
|
coiled coil region
|
672 |
707 |
N/A |
INTRINSIC |
|
coiled coil region
|
728 |
878 |
N/A |
INTRINSIC |
|
coiled coil region
|
900 |
974 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108751
|
| SMART Domains |
Protein: ENSMUSP00000104382
Gene: ENSMUSG00000005417
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
44 |
152 |
3.33e-10 |
SMART |
|
low complexity region
|
183 |
196 |
N/A |
INTRINSIC |
|
Blast:PH
|
216 |
282 |
1e-10 |
BLAST |
|
PH
|
349 |
446 |
3.76e-18 |
SMART |
|
low complexity region
|
490 |
499 |
N/A |
INTRINSIC |
|
low complexity region
|
534 |
553 |
N/A |
INTRINSIC |
|
coiled coil region
|
634 |
669 |
N/A |
INTRINSIC |
|
coiled coil region
|
690 |
840 |
N/A |
INTRINSIC |
|
coiled coil region
|
862 |
936 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000116371
|
| SMART Domains |
Protein: ENSMUSP00000112072
Gene: ENSMUSG00000005417
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
44 |
152 |
3.33e-10 |
SMART |
|
low complexity region
|
179 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
221 |
234 |
N/A |
INTRINSIC |
|
Blast:PH
|
254 |
320 |
1e-10 |
BLAST |
|
PH
|
387 |
484 |
3.76e-18 |
SMART |
|
low complexity region
|
528 |
537 |
N/A |
INTRINSIC |
|
low complexity region
|
572 |
591 |
N/A |
INTRINSIC |
|
coiled coil region
|
672 |
707 |
N/A |
INTRINSIC |
|
coiled coil region
|
728 |
878 |
N/A |
INTRINSIC |
|
coiled coil region
|
900 |
974 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132620
|
| SMART Domains |
Protein: ENSMUSP00000119422
Gene: ENSMUSG00000005417
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
26 |
37 |
N/A |
INTRINSIC |
|
low complexity region
|
68 |
81 |
N/A |
INTRINSIC |
|
Blast:PH
|
101 |
167 |
9e-11 |
BLAST |
|
PH
|
198 |
295 |
3.76e-18 |
SMART |
|
low complexity region
|
339 |
348 |
N/A |
INTRINSIC |
|
low complexity region
|
383 |
402 |
N/A |
INTRINSIC |
|
coiled coil region
|
482 |
517 |
N/A |
INTRINSIC |
|
coiled coil region
|
538 |
688 |
N/A |
INTRINSIC |
|
coiled coil region
|
710 |
784 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000133861
|
| SMART Domains |
Protein: ENSMUSP00000119562
Gene: ENSMUSG00000005417
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
18 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
47 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
89 |
102 |
N/A |
INTRINSIC |
|
low complexity region
|
152 |
162 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
269 |
N/A |
INTRINSIC |
|
PH
|
373 |
470 |
3.76e-18 |
SMART |
|
low complexity region
|
514 |
523 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
577 |
N/A |
INTRINSIC |
|
coiled coil region
|
658 |
693 |
N/A |
INTRINSIC |
|
coiled coil region
|
714 |
864 |
N/A |
INTRINSIC |
|
coiled coil region
|
886 |
960 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156111
|
| SMART Domains |
Protein: ENSMUSP00000114446
Gene: ENSMUSG00000005417
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
5 |
38 |
1.61e-7 |
PROSPERO |
|
internal_repeat_2
|
9 |
51 |
2.4e-6 |
PROSPERO |
|
internal_repeat_1
|
59 |
92 |
1.61e-7 |
PROSPERO |
|
internal_repeat_2
|
85 |
129 |
2.4e-6 |
PROSPERO |
|
coiled coil region
|
140 |
177 |
N/A |
INTRINSIC |
|
coiled coil region
|
201 |
351 |
N/A |
INTRINSIC |
|
coiled coil region
|
373 |
447 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.5%
- 20x: 95.8%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 67 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A4gnt |
T |
A |
9: 99,502,597 (GRCm39) |
N252K |
probably damaging |
Het |
| Abhd16a |
A |
G |
17: 35,313,278 (GRCm39) |
E132G |
probably damaging |
Het |
| Adgrv1 |
G |
A |
13: 81,677,165 (GRCm39) |
R1889W |
possibly damaging |
Het |
| Aftph |
A |
T |
11: 20,677,203 (GRCm39) |
D135E |
probably benign |
Het |
| Arf1 |
A |
C |
11: 59,104,041 (GRCm39) |
F63V |
probably damaging |
Het |
| Atg14 |
G |
A |
14: 47,805,656 (GRCm39) |
R70C |
probably damaging |
Het |
| B3gnt7 |
T |
A |
1: 86,233,366 (GRCm39) |
F87Y |
probably damaging |
Het |
| Bcat1 |
A |
G |
6: 144,953,353 (GRCm39) |
Y345H |
possibly damaging |
Het |
| Birc2 |
G |
T |
9: 7,857,360 (GRCm39) |
T371K |
probably benign |
Het |
| Ccdc175 |
A |
T |
12: 72,231,745 (GRCm39) |
S5T |
probably damaging |
Het |
| Ccdc186 |
A |
T |
19: 56,801,689 (GRCm39) |
S143T |
possibly damaging |
Het |
| Cct6b |
A |
T |
11: 82,653,015 (GRCm39) |
M28K |
possibly damaging |
Het |
| Cers4 |
C |
A |
8: 4,565,680 (GRCm39) |
A42D |
probably damaging |
Het |
| Crmp1 |
G |
T |
5: 37,437,018 (GRCm39) |
V236L |
probably benign |
Het |
| Ctdspl2 |
T |
A |
2: 121,811,793 (GRCm39) |
N212K |
probably benign |
Het |
| Dclk3 |
T |
C |
9: 111,298,127 (GRCm39) |
V557A |
possibly damaging |
Het |
| Dnmt1 |
A |
T |
9: 20,864,015 (GRCm39) |
H23Q |
probably benign |
Het |
| Dpp8 |
G |
T |
9: 64,971,206 (GRCm39) |
E609* |
probably null |
Het |
| Dtx3 |
C |
A |
10: 127,028,919 (GRCm39) |
M106I |
probably benign |
Het |
| Ero1b |
A |
C |
13: 12,589,732 (GRCm39) |
D45A |
probably damaging |
Het |
| Fcho2 |
T |
A |
13: 98,867,399 (GRCm39) |
D688V |
probably damaging |
Het |
| Fhod3 |
A |
T |
18: 25,161,138 (GRCm39) |
S557C |
probably damaging |
Het |
| Flnc |
T |
C |
6: 29,444,063 (GRCm39) |
S626P |
possibly damaging |
Het |
| Foxi3 |
G |
T |
6: 70,937,602 (GRCm39) |
G278V |
probably damaging |
Het |
| Gbp10 |
A |
G |
5: 105,372,166 (GRCm39) |
L198P |
probably damaging |
Het |
| Gcn1 |
A |
G |
5: 115,721,462 (GRCm39) |
T458A |
probably benign |
Het |
| Gigyf1 |
C |
T |
5: 137,521,422 (GRCm39) |
|
probably benign |
Het |
| Gtpbp2 |
A |
C |
17: 46,478,760 (GRCm39) |
T526P |
probably damaging |
Het |
| Gys2 |
A |
G |
6: 142,400,239 (GRCm39) |
L324S |
probably damaging |
Het |
| Hpn |
C |
A |
7: 30,802,781 (GRCm39) |
V119L |
probably benign |
Het |
| Ino80d |
C |
A |
1: 63,098,098 (GRCm39) |
V599L |
probably benign |
Het |
| Kcnh3 |
G |
T |
15: 99,140,275 (GRCm39) |
G1054* |
probably null |
Het |
| Maml1 |
A |
T |
11: 50,157,778 (GRCm39) |
D132E |
probably benign |
Het |
| Mastl |
A |
T |
2: 23,023,503 (GRCm39) |
S407T |
probably benign |
Het |
| Mettl1 |
T |
C |
10: 126,878,954 (GRCm39) |
W3R |
probably damaging |
Het |
| Mylk3 |
T |
C |
8: 86,069,350 (GRCm39) |
N484D |
probably damaging |
Het |
| Nod2 |
G |
A |
8: 89,399,413 (GRCm39) |
|
probably null |
Het |
| Nrde2 |
A |
T |
12: 100,097,037 (GRCm39) |
F921Y |
probably damaging |
Het |
| Nup88 |
G |
T |
11: 70,835,734 (GRCm39) |
T575N |
probably damaging |
Het |
| Nxpe3 |
T |
C |
16: 55,686,706 (GRCm39) |
T101A |
possibly damaging |
Het |
| Or1o3 |
T |
A |
17: 37,574,532 (GRCm39) |
T8S |
probably benign |
Het |
| Or2r11 |
A |
G |
6: 42,437,908 (GRCm39) |
M15T |
probably benign |
Het |
| Or4c109 |
C |
T |
2: 88,817,809 (GRCm39) |
V246I |
possibly damaging |
Het |
| Or52e15 |
A |
G |
7: 104,645,514 (GRCm39) |
L199S |
possibly damaging |
Het |
| Or8g32 |
A |
T |
9: 39,305,371 (GRCm39) |
I92F |
probably damaging |
Het |
| Pcnx3 |
A |
T |
19: 5,722,624 (GRCm39) |
L1356Q |
probably damaging |
Het |
| Pkd1 |
A |
T |
17: 24,813,510 (GRCm39) |
M4017L |
probably benign |
Het |
| Polg2 |
A |
G |
11: 106,670,064 (GRCm39) |
C69R |
possibly damaging |
Het |
| Prr5l |
T |
G |
2: 101,547,452 (GRCm39) |
S358R |
probably benign |
Het |
| Ptprg |
A |
G |
14: 12,154,111 (GRCm38) |
T611A |
probably benign |
Het |
| Ryk |
G |
T |
9: 102,774,516 (GRCm39) |
E417* |
probably null |
Het |
| Sbp |
T |
C |
17: 24,161,396 (GRCm39) |
|
probably benign |
Het |
| Sema4a |
T |
C |
3: 88,358,804 (GRCm39) |
T155A |
probably benign |
Het |
| Shank3 |
A |
G |
15: 89,415,914 (GRCm39) |
|
probably null |
Het |
| Slc35d2 |
A |
T |
13: 64,245,496 (GRCm39) |
M294K |
possibly damaging |
Het |
| Slc41a3 |
A |
T |
6: 90,589,153 (GRCm39) |
N88I |
possibly damaging |
Het |
| Slit3 |
A |
G |
11: 35,512,975 (GRCm39) |
T534A |
probably benign |
Het |
| Ssx2ip |
A |
G |
3: 146,142,296 (GRCm39) |
|
probably null |
Het |
| Stard13 |
T |
C |
5: 150,983,063 (GRCm39) |
K648R |
probably damaging |
Het |
| Tanc1 |
A |
T |
2: 59,626,178 (GRCm39) |
T512S |
probably damaging |
Het |
| Tbcc |
T |
C |
17: 47,202,082 (GRCm39) |
V156A |
probably benign |
Het |
| Terf1 |
T |
G |
1: 15,901,787 (GRCm39) |
I273R |
possibly damaging |
Het |
| Tesc |
A |
G |
5: 118,197,523 (GRCm39) |
Y179C |
probably damaging |
Het |
| Ttc3 |
T |
G |
16: 94,184,900 (GRCm39) |
V40G |
probably damaging |
Het |
| Tysnd1 |
T |
A |
10: 61,532,028 (GRCm39) |
F227I |
probably damaging |
Het |
| Vps53 |
T |
C |
11: 75,972,034 (GRCm39) |
E271G |
probably damaging |
Het |
| Wdfy4 |
C |
T |
14: 32,812,823 (GRCm39) |
R1650H |
probably damaging |
Het |
|
| Other mutations in Mprip |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00334:Mprip
|
APN |
11 |
59,639,417 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00563:Mprip
|
APN |
11 |
59,643,443 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00905:Mprip
|
APN |
11 |
59,662,994 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL00928:Mprip
|
APN |
11 |
59,635,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01161:Mprip
|
APN |
11 |
59,622,399 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01991:Mprip
|
APN |
11 |
59,645,838 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02491:Mprip
|
APN |
11 |
59,660,857 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL03030:Mprip
|
APN |
11 |
59,631,941 (GRCm39) |
splice site |
probably null |
|
|
IGL03056:Mprip
|
APN |
11 |
59,662,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03293:Mprip
|
APN |
11 |
59,586,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0049:Mprip
|
UTSW |
11 |
59,657,571 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0097:Mprip
|
UTSW |
11 |
59,649,317 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0097:Mprip
|
UTSW |
11 |
59,649,317 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0147:Mprip
|
UTSW |
11 |
59,627,899 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0319:Mprip
|
UTSW |
11 |
59,587,864 (GRCm39) |
splice site |
probably benign |
|
|
R0471:Mprip
|
UTSW |
11 |
59,650,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0539:Mprip
|
UTSW |
11 |
59,631,943 (GRCm39) |
splice site |
probably benign |
|
|
R0627:Mprip
|
UTSW |
11 |
59,660,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0864:Mprip
|
UTSW |
11 |
59,649,587 (GRCm39) |
missense |
probably benign |
|
|
R1218:Mprip
|
UTSW |
11 |
59,634,640 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Mprip
|
UTSW |
11 |
59,650,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Mprip
|
UTSW |
11 |
59,650,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1695:Mprip
|
UTSW |
11 |
59,643,357 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1698:Mprip
|
UTSW |
11 |
59,651,084 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1802:Mprip
|
UTSW |
11 |
59,645,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1837:Mprip
|
UTSW |
11 |
59,657,571 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1862:Mprip
|
UTSW |
11 |
59,649,047 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R2094:Mprip
|
UTSW |
11 |
59,640,334 (GRCm39) |
splice site |
probably benign |
|
|
R2107:Mprip
|
UTSW |
11 |
59,660,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2108:Mprip
|
UTSW |
11 |
59,660,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2510:Mprip
|
UTSW |
11 |
59,640,334 (GRCm39) |
splice site |
probably benign |
|
|
R3003:Mprip
|
UTSW |
11 |
59,618,381 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3115:Mprip
|
UTSW |
11 |
59,656,229 (GRCm39) |
splice site |
probably null |
|
|
R3941:Mprip
|
UTSW |
11 |
59,622,328 (GRCm39) |
splice site |
probably benign |
|
|
R4347:Mprip
|
UTSW |
11 |
59,650,279 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4603:Mprip
|
UTSW |
11 |
59,622,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4807:Mprip
|
UTSW |
11 |
59,648,846 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5011:Mprip
|
UTSW |
11 |
59,650,721 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5549:Mprip
|
UTSW |
11 |
59,651,644 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5569:Mprip
|
UTSW |
11 |
59,651,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5604:Mprip
|
UTSW |
11 |
59,649,293 (GRCm39) |
missense |
probably benign |
|
|
R5615:Mprip
|
UTSW |
11 |
59,649,313 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5846:Mprip
|
UTSW |
11 |
59,649,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5970:Mprip
|
UTSW |
11 |
59,648,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6054:Mprip
|
UTSW |
11 |
59,649,251 (GRCm39) |
missense |
probably benign |
|
|
R6452:Mprip
|
UTSW |
11 |
59,643,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6457:Mprip
|
UTSW |
11 |
59,649,815 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6544:Mprip
|
UTSW |
11 |
59,648,552 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6750:Mprip
|
UTSW |
11 |
59,586,957 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6843:Mprip
|
UTSW |
11 |
59,650,554 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R6851:Mprip
|
UTSW |
11 |
59,649,841 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6867:Mprip
|
UTSW |
11 |
59,640,456 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7002:Mprip
|
UTSW |
11 |
59,652,016 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7023:Mprip
|
UTSW |
11 |
59,628,215 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7764:Mprip
|
UTSW |
11 |
59,655,242 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7765:Mprip
|
UTSW |
11 |
59,649,047 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7828:Mprip
|
UTSW |
11 |
59,627,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7866:Mprip
|
UTSW |
11 |
59,643,756 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R7911:Mprip
|
UTSW |
11 |
59,651,681 (GRCm39) |
missense |
|
|
|
R7979:Mprip
|
UTSW |
11 |
59,657,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8292:Mprip
|
UTSW |
11 |
59,650,340 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8481:Mprip
|
UTSW |
11 |
59,648,982 (GRCm39) |
nonsense |
probably null |
|
|
R8717:Mprip
|
UTSW |
11 |
59,650,526 (GRCm39) |
missense |
probably benign |
|
|
R8810:Mprip
|
UTSW |
11 |
59,587,851 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R8981:Mprip
|
UTSW |
11 |
59,622,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9214:Mprip
|
UTSW |
11 |
59,650,901 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9245:Mprip
|
UTSW |
11 |
59,628,403 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9748:Mprip
|
UTSW |
11 |
59,656,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Mprip
|
UTSW |
11 |
59,650,310 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1176:Mprip
|
UTSW |
11 |
59,628,230 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
Z1177:Mprip
|
UTSW |
11 |
59,648,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATTTCAGCTGCCTTGCCAG -3'
(R):5'- TCTGCTGATGGTCCATCTGG -3'
Sequencing Primer
(F):5'- AGTCCTGCCTCCTACAGAG -3'
(R):5'- ACTTTGGCCTTGAGCTCAG -3'
|
| Posted On |
2016-08-04 |
Incidental Mutation