Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01793:Vmn1r180'

155259

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r180

Ensembl Gene

ENSMUSG00000092473

Gene Name

vomeronasal 1 receptor 180

Synonyms

V1rd16, LOC232962

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.054) question?

Stock #

IGL01793

Quality Score

Status

Chromosome

Chromosomal Location

23651812-23652781 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 23652668 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 277 (V277A)

Ref Sequence

ENSEMBL: ENSMUSP00000134362 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000173816]

AlphaFold

B9EK86

Predicted Effect

probably benign
Transcript: ENSMUST00000173816
AA Change: V277A

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)

SMART Domains

Protein: ENSMUSP00000134362
Gene: ENSMUSG00000092473
AA Change: V277A

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	298	2.9e-15	PFAM
Pfam:7tm_1	31	286	6.7e-9	PFAM
Pfam:V1R	41	297	1.4e-17	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 29 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aox1	A	G	1: 58,375,783 (GRCm39)	I871V	possibly damaging	Het
Bbs7	A	T	3: 36,659,831 (GRCm39)		probably null	Het
D930020B18Rik	T	C	10: 121,507,736 (GRCm39)	I158T	probably damaging	Het
Drc7	T	C	8: 95,797,905 (GRCm39)	I441T	probably benign	Het
Etl4	T	C	2: 20,748,709 (GRCm39)	I147T	possibly damaging	Het
Fat1	G	A	8: 45,442,149 (GRCm39)	M1150I	probably benign	Het
Fbn1	T	C	2: 125,229,213 (GRCm39)	S523G	possibly damaging	Het
Gramd1a	C	T	7: 30,833,838 (GRCm39)		probably null	Het
Hc	A	G	2: 34,918,202 (GRCm39)	Y694H	probably damaging	Het
Kif6	T	A	17: 49,931,521 (GRCm39)	I73N	probably damaging	Het
Large1	A	G	8: 73,585,809 (GRCm39)		probably benign	Het
Luzp2	G	T	7: 54,821,997 (GRCm39)	L171F	probably damaging	Het
Naaladl1	C	A	19: 6,159,661 (GRCm39)		probably null	Het
Otop1	G	A	5: 38,457,215 (GRCm39)	A325T	possibly damaging	Het
Parp8	T	A	13: 117,047,415 (GRCm39)	Y219F	probably damaging	Het
Pkp3	A	G	7: 140,668,817 (GRCm39)	I660V	probably benign	Het
Plin3	T	C	17: 56,588,540 (GRCm39)	N238S	probably benign	Het
Ppef2	A	T	5: 92,394,615 (GRCm39)	D186E	probably damaging	Het
Rab40c	G	A	17: 26,103,596 (GRCm39)	L156F	probably damaging	Het
Scnn1a	T	C	6: 125,320,666 (GRCm39)	V547A	probably benign	Het
Spag6l	A	G	16: 16,599,721 (GRCm39)	V247A	probably damaging	Het
Syne1	T	C	10: 5,302,191 (GRCm39)	E853G	possibly damaging	Het
Synj2	C	T	17: 6,077,500 (GRCm39)	R460*	probably null	Het
Synj2	T	A	17: 6,088,321 (GRCm39)	H1457Q	probably benign	Het
Syt1	T	C	10: 108,419,836 (GRCm39)	D275G	possibly damaging	Het
Tmx1	A	G	12: 70,505,561 (GRCm39)	D108G	probably benign	Het
Vmn1r83	C	T	7: 12,055,504 (GRCm39)	M184I	probably benign	Het
Zfp750	G	T	11: 121,404,810 (GRCm39)	P22T	probably damaging	Het
Zscan2	A	G	7: 80,524,692 (GRCm39)	I138V	probably null	Het

Other mutations in Vmn1r180

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00487:Vmn1r180	APN	7	23,651,948 (GRCm39)	missense	probably benign	0.36
IGL01309:Vmn1r180	APN	7	23,652,424 (GRCm39)	missense	probably damaging	1.00
IGL02653:Vmn1r180	APN	7	23,652,500 (GRCm39)	missense	probably damaging	1.00
IGL03277:Vmn1r180	APN	7	23,652,710 (GRCm39)	missense	probably damaging	0.99
IGL03352:Vmn1r180	APN	7	23,652,077 (GRCm39)	nonsense	probably null
R1298:Vmn1r180	UTSW	7	23,652,572 (GRCm39)	missense	possibly damaging	0.84
R1701:Vmn1r180	UTSW	7	23,652,395 (GRCm39)	missense	possibly damaging	0.84
R1702:Vmn1r180	UTSW	7	23,652,394 (GRCm39)	missense	possibly damaging	0.52
R2122:Vmn1r180	UTSW	7	23,652,566 (GRCm39)	missense	probably damaging	1.00
R4241:Vmn1r180	UTSW	7	23,652,298 (GRCm39)	missense	probably damaging	1.00
R5683:Vmn1r180	UTSW	7	23,652,635 (GRCm39)	missense	possibly damaging	0.58
R7241:Vmn1r180	UTSW	7	23,651,891 (GRCm39)	missense	probably damaging	0.96
R7522:Vmn1r180	UTSW	7	23,652,685 (GRCm39)	missense	probably damaging	1.00
R8749:Vmn1r180	UTSW	7	23,652,415 (GRCm39)	missense	probably damaging	1.00
R8991:Vmn1r180	UTSW	7	23,652,076 (GRCm39)	missense	probably benign	0.06
R9442:Vmn1r180	UTSW	7	23,651,620 (GRCm39)	start gained	probably benign

Posted On

2014-02-04