Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01793:Vmn1r180'

155259

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r180

Ensembl Gene

ENSMUSG00000092473

Gene Name

vomeronasal 1 receptor 180

Synonyms

LOC232962, V1rd16

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.059) question?

Stock #

IGL01793

Quality Score

Status

Chromosome

Chromosomal Location

23950632-23955691 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 23953243 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 277 (V277A)

Ref Sequence

ENSEMBL: ENSMUSP00000134362 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000173816]

AlphaFold

B9EK86

Predicted Effect

probably benign
Transcript: ENSMUST00000173816
AA Change: V277A

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)

SMART Domains

Protein: ENSMUSP00000134362
Gene: ENSMUSG00000092473
AA Change: V277A

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	298	2.9e-15	PFAM
Pfam:7tm_1	31	286	6.7e-9	PFAM
Pfam:V1R	41	297	1.4e-17	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 29 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aox2	A	G	1: 58,336,624	I871V	possibly damaging	Het
Bbs7	A	T	3: 36,605,682		probably null	Het
D930020B18Rik	T	C	10: 121,671,831	I158T	probably damaging	Het
Drc7	T	C	8: 95,071,277	I441T	probably benign	Het
Etl4	T	C	2: 20,743,898	I147T	possibly damaging	Het
Fat1	G	A	8: 44,989,112	M1150I	probably benign	Het
Fbn1	T	C	2: 125,387,293	S523G	possibly damaging	Het
Gramd1a	C	T	7: 31,134,413		probably null	Het
Hc	A	G	2: 35,028,190	Y694H	probably damaging	Het
Kif6	T	A	17: 49,624,493	I73N	probably damaging	Het
Large1	A	G	8: 72,859,181		probably benign	Het
Luzp2	G	T	7: 55,172,249	L171F	probably damaging	Het
Naaladl1	C	A	19: 6,109,631		probably null	Het
Otop1	G	A	5: 38,299,871	A325T	possibly damaging	Het
Parp8	T	A	13: 116,910,879	Y219F	probably damaging	Het
Pkp3	A	G	7: 141,088,904	I660V	probably benign	Het
Plin3	T	C	17: 56,281,540	N238S	probably benign	Het
Ppef2	A	T	5: 92,246,756	D186E	probably damaging	Het
Rab40c	G	A	17: 25,884,622	L156F	probably damaging	Het
Scnn1a	T	C	6: 125,343,703	V547A	probably benign	Het
Spag6l	A	G	16: 16,781,857	V247A	probably damaging	Het
Syne1	T	C	10: 5,352,191	E853G	possibly damaging	Het
Synj2	T	A	17: 6,038,046	H1457Q	probably benign	Het
Synj2	C	T	17: 6,027,225	R460*	probably null	Het
Syt1	T	C	10: 108,583,975	D275G	possibly damaging	Het
Tmx1	A	G	12: 70,458,787	D108G	probably benign	Het
Vmn1r83	C	T	7: 12,321,577	M184I	probably benign	Het
Zfp750	G	T	11: 121,513,984	P22T	probably damaging	Het
Zscan2	A	G	7: 80,874,944	I138V	probably null	Het

Other mutations in Vmn1r180

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00487:Vmn1r180	APN	7	23952523	missense	probably benign	0.36
IGL01309:Vmn1r180	APN	7	23952999	missense	probably damaging	1.00
IGL02653:Vmn1r180	APN	7	23953075	missense	probably damaging	1.00
IGL03277:Vmn1r180	APN	7	23953285	missense	probably damaging	0.99
IGL03352:Vmn1r180	APN	7	23952652	nonsense	probably null
R1298:Vmn1r180	UTSW	7	23953147	missense	possibly damaging	0.84
R1701:Vmn1r180	UTSW	7	23952970	missense	possibly damaging	0.84
R1702:Vmn1r180	UTSW	7	23952969	missense	possibly damaging	0.52
R2122:Vmn1r180	UTSW	7	23953141	missense	probably damaging	1.00
R4241:Vmn1r180	UTSW	7	23952873	missense	probably damaging	1.00
R5683:Vmn1r180	UTSW	7	23953210	missense	possibly damaging	0.58
R7241:Vmn1r180	UTSW	7	23952466	missense	probably damaging	0.96
R7522:Vmn1r180	UTSW	7	23953260	missense	probably damaging	1.00
R8749:Vmn1r180	UTSW	7	23952990	missense	probably damaging	1.00
R8991:Vmn1r180	UTSW	7	23952651	missense	probably benign	0.06
R9442:Vmn1r180	UTSW	7	23952195	start gained	probably benign

Posted On

2014-02-04