Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02026:Vmn1r64'

184165

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r64

Ensembl Gene

ENSMUSG00000058399

Gene Name

vomeronasal 1 receptor 64

Synonyms

V1rd11

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.053) question?

Stock #

IGL02026

Quality Score

Status

Chromosome

Chromosomal Location

5886579-5887541 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 5886649 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Proline to Leucine at position 298 (P298L)

Ref Sequence

ENSEMBL: ENSMUSP00000077568 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000078475]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000078475
AA Change: P298L

PolyPhen 2 Score 0.843 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000077568
Gene: ENSMUSG00000058399
AA Change: P298L

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	296	3.3e-13	PFAM
Pfam:V1R	41	296	1.5e-19	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adamdec1	A	T	14: 68,809,251 (GRCm39)	V237E	possibly damaging	Het
Amh	T	C	10: 80,641,242 (GRCm39)	L54P	probably damaging	Het
Aoc3	T	C	11: 101,228,421 (GRCm39)	S743P	probably benign	Het
Arhgap23	T	A	11: 97,342,407 (GRCm39)	W19R	probably damaging	Het
Atm	C	T	9: 53,353,717 (GRCm39)		probably null	Het
Ccdc47	T	C	11: 106,095,853 (GRCm39)	E281G	probably damaging	Het
Col7a1	A	C	9: 108,797,097 (GRCm39)	K1650N	probably damaging	Het
Cstdc5	C	A	16: 36,187,848 (GRCm39)	V6F	possibly damaging	Het
Evi2b	T	C	11: 79,406,613 (GRCm39)	S321G	probably damaging	Het
Fancm	T	G	12: 65,152,508 (GRCm39)	V988G	probably benign	Het
Gbp2	A	G	3: 142,339,241 (GRCm39)	Y431C	probably damaging	Het
Gclc	T	C	9: 77,699,342 (GRCm39)	V530A	probably benign	Het
Gm5885	T	C	6: 133,508,291 (GRCm39)		noncoding transcript	Het
Hlcs	A	T	16: 93,935,564 (GRCm39)	I576N	probably damaging	Het
Hnrnpul1	A	T	7: 25,444,587 (GRCm39)	F240L	probably damaging	Het
Itgb6	C	A	2: 60,458,410 (GRCm39)	V448F	possibly damaging	Het
Lama1	A	G	17: 68,116,287 (GRCm39)	T2385A	possibly damaging	Het
Lamc2	C	T	1: 153,020,482 (GRCm39)		probably benign	Het
Lrrc32	C	T	7: 98,148,767 (GRCm39)	R516C	probably benign	Het
Lrrtm3	T	C	10: 63,924,231 (GRCm39)	N312S	probably damaging	Het
Ltbp4	G	A	7: 27,026,842 (GRCm39)	R468*	probably null	Het
Man1a	T	C	10: 53,890,569 (GRCm39)	E373G	probably damaging	Het
Myo1h	A	T	5: 114,461,505 (GRCm39)	Q250L	probably null	Het
Myo9a	T	C	9: 59,813,245 (GRCm39)	V2077A	probably damaging	Het
Or14j3	A	G	17: 37,900,298 (GRCm39)		probably benign	Het
Otud5	C	T	X: 7,738,232 (GRCm39)		probably benign	Het
Pcsk1	A	G	13: 75,260,772 (GRCm39)	S332G	probably benign	Het
Pde8b	A	G	13: 95,170,869 (GRCm39)	V549A	probably damaging	Het
Pgap1	A	T	1: 54,533,978 (GRCm39)	M645K	probably benign	Het
Pm20d1	A	T	1: 131,729,497 (GRCm39)	R175*	probably null	Het
Polr2b	A	G	5: 77,480,099 (GRCm39)	N585S	probably benign	Het
Recql	T	A	6: 142,312,394 (GRCm39)	K41*	probably null	Het
Sccpdh	A	T	1: 179,505,634 (GRCm39)	H138L	possibly damaging	Het
Sec31a	A	T	5: 100,517,485 (GRCm39)	S951T	probably benign	Het
Slc44a4	A	T	17: 35,140,832 (GRCm39)		probably benign	Het
Tchhl1	G	T	3: 93,377,862 (GRCm39)	A189S	probably damaging	Het
Tdrd12	G	A	7: 35,203,658 (GRCm39)		probably benign	Het
Tesl2	T	G	X: 23,824,233 (GRCm39)	H314P	probably damaging	Het
Trbv12-1	A	G	6: 41,090,928 (GRCm39)	D100G	probably damaging	Het
Ttll13	T	A	7: 79,910,127 (GRCm39)	S757T	probably benign	Het
Vipas39	T	A	12: 87,298,483 (GRCm39)		probably benign	Het
Vmn1r81	A	G	7: 11,994,432 (GRCm39)	S59P	probably damaging	Het
Vsx1	A	T	2: 150,530,447 (GRCm39)	V145D	probably benign	Het
Wdfy4	T	A	14: 32,815,257 (GRCm39)	N1586I	probably damaging	Het
Zan	T	A	5: 137,403,726 (GRCm39)		probably benign	Het
Zfp318	C	T	17: 46,707,736 (GRCm39)	R265*	probably null	Het
Zzef1	T	A	11: 72,772,164 (GRCm39)	M1707K	probably benign	Het

Other mutations in Vmn1r64

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Vmn1r64	APN	7	5,886,827 (GRCm39)	missense	probably damaging	0.98
IGL01070:Vmn1r64	APN	7	5,886,941 (GRCm39)	missense	probably benign	0.04
IGL01817:Vmn1r64	APN	7	5,887,222 (GRCm39)	missense	probably damaging	1.00
IGL02657:Vmn1r64	APN	7	5,886,727 (GRCm39)	missense	probably benign	0.33
IGL03352:Vmn1r64	APN	7	5,887,070 (GRCm39)	missense	probably benign	0.12
R0200:Vmn1r64	UTSW	7	5,886,817 (GRCm39)	missense	probably benign	0.38
R0540:Vmn1r64	UTSW	7	5,887,096 (GRCm39)	missense	probably damaging	1.00
R0655:Vmn1r64	UTSW	7	5,887,207 (GRCm39)	missense	probably benign	0.25
R1212:Vmn1r64	UTSW	7	5,887,210 (GRCm39)	missense	probably damaging	1.00
R1579:Vmn1r64	UTSW	7	5,886,803 (GRCm39)	missense	probably damaging	1.00
R2034:Vmn1r64	UTSW	7	5,886,988 (GRCm39)	missense	probably benign	0.09
R2221:Vmn1r64	UTSW	7	5,887,448 (GRCm39)	missense	probably benign	0.00
R2240:Vmn1r64	UTSW	7	5,887,369 (GRCm39)	nonsense	probably null
R2305:Vmn1r64	UTSW	7	5,887,535 (GRCm39)	missense	probably benign	0.04
R3019:Vmn1r64	UTSW	7	5,887,226 (GRCm39)	missense	probably damaging	1.00
R4256:Vmn1r64	UTSW	7	5,886,895 (GRCm39)	missense	probably benign	0.05
R4666:Vmn1r64	UTSW	7	5,887,357 (GRCm39)	missense	probably damaging	0.99
R4996:Vmn1r64	UTSW	7	5,887,052 (GRCm39)	missense	probably benign	0.03
R5682:Vmn1r64	UTSW	7	5,886,622 (GRCm39)	missense	possibly damaging	0.79
R5730:Vmn1r64	UTSW	7	5,887,522 (GRCm39)	missense	probably benign	0.01
R7397:Vmn1r64	UTSW	7	5,887,013 (GRCm39)	missense	possibly damaging	0.87
R9697:Vmn1r64	UTSW	7	5,886,859 (GRCm39)	missense	probably benign	0.04
X0063:Vmn1r64	UTSW	7	5,887,349 (GRCm39)	missense	probably benign	0.00

Posted On

2014-05-07