Incidental Mutation 'IGL02082:Vmn1r222'
| ID |
283389 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r222
|
| Ensembl Gene |
ENSMUSG00000061022 |
| Gene Name |
vomeronasal 1 receptor 222 |
| Synonyms |
V1rh16 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.079)
|
| Stock # |
IGL02082
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
13 |
| Chromosomal Location |
23416285-23417211 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 23416499 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Threonine
at position 238
(M238T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000076365
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000077116]
|
| AlphaFold |
Q8R269 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000077116
AA Change: M238T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000076365
Gene: ENSMUSG00000061022
AA Change: M238T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:V1R
|
32 |
297 |
3.6e-39 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000225143
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 23 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Atp9b |
A |
C |
18: 80,935,145 (GRCm39) |
|
probably benign |
Het |
| Brinp3 |
T |
C |
1: 146,627,600 (GRCm39) |
C278R |
probably damaging |
Het |
| Cfap54 |
T |
C |
10: 92,917,320 (GRCm39) |
S47G |
unknown |
Het |
| Clec16a |
T |
C |
16: 10,432,432 (GRCm39) |
L484P |
probably damaging |
Het |
| Cnksr1 |
C |
A |
4: 133,963,363 (GRCm39) |
G71C |
probably damaging |
Het |
| Dnah12 |
A |
T |
14: 26,428,317 (GRCm39) |
N246I |
possibly damaging |
Het |
| Fbh1 |
T |
C |
2: 11,768,938 (GRCm39) |
D285G |
probably benign |
Het |
| Focad |
C |
T |
4: 88,148,815 (GRCm39) |
Q511* |
probably null |
Het |
| Gpr63 |
A |
G |
4: 25,008,564 (GRCm39) |
|
probably benign |
Het |
| Iah1 |
C |
A |
12: 21,367,405 (GRCm39) |
S37* |
probably null |
Het |
| Inpp4a |
T |
A |
1: 37,405,708 (GRCm39) |
|
probably benign |
Het |
| Mcm2 |
A |
T |
6: 88,865,218 (GRCm39) |
Y486* |
probably null |
Het |
| Mtmr10 |
A |
G |
7: 63,983,238 (GRCm39) |
|
probably benign |
Het |
| Nbea |
A |
G |
3: 55,875,588 (GRCm39) |
L1694S |
possibly damaging |
Het |
| Pafah1b1 |
A |
G |
11: 74,590,159 (GRCm39) |
S4P |
probably benign |
Het |
| Rnase10 |
A |
T |
14: 51,246,856 (GRCm39) |
E41V |
probably damaging |
Het |
| Slc17a6 |
G |
T |
7: 51,318,777 (GRCm39) |
R473L |
probably benign |
Het |
| Spata31g1 |
A |
G |
4: 42,970,198 (GRCm39) |
T2A |
probably benign |
Het |
| Tbc1d9b |
A |
G |
11: 50,054,709 (GRCm39) |
D951G |
probably benign |
Het |
| Tk1 |
C |
A |
11: 117,716,553 (GRCm39) |
|
probably null |
Het |
| Trim46 |
C |
A |
3: 89,146,307 (GRCm39) |
A395S |
probably benign |
Het |
| Vmn1r113 |
C |
T |
7: 20,521,672 (GRCm39) |
H155Y |
probably benign |
Het |
| Vmn2r72 |
A |
T |
7: 85,387,374 (GRCm39) |
V730E |
probably benign |
Het |
|
| Other mutations in Vmn1r222 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01539:Vmn1r222
|
APN |
13 |
23,417,059 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL01960:Vmn1r222
|
APN |
13 |
23,416,315 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02616:Vmn1r222
|
APN |
13 |
23,416,311 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL03155:Vmn1r222
|
APN |
13 |
23,416,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03333:Vmn1r222
|
APN |
13 |
23,417,177 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL03391:Vmn1r222
|
APN |
13 |
23,416,632 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0137:Vmn1r222
|
UTSW |
13 |
23,416,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1584:Vmn1r222
|
UTSW |
13 |
23,416,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2352:Vmn1r222
|
UTSW |
13 |
23,416,683 (GRCm39) |
missense |
probably benign |
0.35 |
|
R3079:Vmn1r222
|
UTSW |
13 |
23,416,631 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R3080:Vmn1r222
|
UTSW |
13 |
23,416,631 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R3963:Vmn1r222
|
UTSW |
13 |
23,417,102 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4448:Vmn1r222
|
UTSW |
13 |
23,416,830 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4448:Vmn1r222
|
UTSW |
13 |
23,416,463 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4979:Vmn1r222
|
UTSW |
13 |
23,416,602 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R5054:Vmn1r222
|
UTSW |
13 |
23,416,901 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5182:Vmn1r222
|
UTSW |
13 |
23,416,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5230:Vmn1r222
|
UTSW |
13 |
23,417,172 (GRCm39) |
missense |
probably benign |
|
|
R5462:Vmn1r222
|
UTSW |
13 |
23,417,045 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5611:Vmn1r222
|
UTSW |
13 |
23,416,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5677:Vmn1r222
|
UTSW |
13 |
23,416,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6298:Vmn1r222
|
UTSW |
13 |
23,416,965 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6655:Vmn1r222
|
UTSW |
13 |
23,416,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6748:Vmn1r222
|
UTSW |
13 |
23,417,117 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6912:Vmn1r222
|
UTSW |
13 |
23,416,374 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7663:Vmn1r222
|
UTSW |
13 |
23,416,601 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7764:Vmn1r222
|
UTSW |
13 |
23,416,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8675:Vmn1r222
|
UTSW |
13 |
23,416,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8774:Vmn1r222
|
UTSW |
13 |
23,416,418 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8774-TAIL:Vmn1r222
|
UTSW |
13 |
23,416,418 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9320:Vmn1r222
|
UTSW |
13 |
23,416,418 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1177:Vmn1r222
|
UTSW |
13 |
23,416,630 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
| Posted On |
2015-04-16 |
Incidental Mutation