Incidental Mutation 'IGL03493:Zfp955b'
| ID |
490708 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp955b
|
| Ensembl Gene |
ENSMUSG00000096910 |
| Gene Name |
zinc finger protein 955B |
| Synonyms |
C430039G02Rik, A430003O12Rik, Gm4455 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.065)
|
| Stock # |
IGL03493
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
33508518-33526215 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 33521519 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 329
(H329Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097011
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099414]
|
| AlphaFold |
L7N232 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000099414
AA Change: H329Q
PolyPhen 2
Score 0.348 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000097011
Gene: ENSMUSG00000096910
AA Change: H329Q
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
10 |
70 |
3.04e-14 |
SMART |
|
ZnF_C2H2
|
230 |
252 |
7.68e0 |
SMART |
|
ZnF_C2H2
|
258 |
280 |
5.72e-1 |
SMART |
|
ZnF_C2H2
|
290 |
312 |
6.75e0 |
SMART |
|
ZnF_C2H2
|
318 |
340 |
5.81e-2 |
SMART |
|
ZnF_C2H2
|
346 |
368 |
3.16e-3 |
SMART |
|
ZnF_C2H2
|
374 |
396 |
1.18e-2 |
SMART |
|
ZnF_C2H2
|
402 |
424 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
430 |
452 |
3.16e-3 |
SMART |
|
ZnF_C2H2
|
458 |
480 |
1.1e-2 |
SMART |
|
ZnF_C2H2
|
486 |
508 |
2.09e-3 |
SMART |
|
ZnF_C2H2
|
514 |
536 |
6.67e-2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182230
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 29 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aldoart1 |
G |
A |
4: 72,769,884 (GRCm39) |
T253I |
probably damaging |
Het |
| Ampd2 |
T |
C |
3: 107,982,674 (GRCm39) |
E694G |
probably damaging |
Het |
| Atcay |
C |
A |
10: 81,046,407 (GRCm39) |
E306* |
probably null |
Het |
| Atp13a5 |
G |
T |
16: 29,116,342 (GRCm39) |
D546E |
probably benign |
Het |
| C2cd2 |
T |
C |
16: 97,682,861 (GRCm39) |
D125G |
probably damaging |
Het |
| Col23a1 |
T |
C |
11: 51,455,632 (GRCm39) |
|
probably null |
Het |
| Col9a1 |
T |
A |
1: 24,260,651 (GRCm39) |
|
probably benign |
Het |
| Cyp4a31 |
T |
A |
4: 115,427,952 (GRCm39) |
|
probably null |
Het |
| Dnah11 |
G |
A |
12: 117,976,533 (GRCm39) |
R2708C |
probably benign |
Het |
| Dzip3 |
T |
C |
16: 48,772,059 (GRCm39) |
I537V |
probably benign |
Het |
| Ezh1 |
T |
C |
11: 101,094,617 (GRCm39) |
T392A |
probably benign |
Het |
| Hsd17b14 |
A |
T |
7: 45,205,515 (GRCm39) |
D42V |
probably damaging |
Het |
| Hsf2 |
A |
T |
10: 57,381,462 (GRCm39) |
I294F |
probably damaging |
Het |
| Ibtk |
G |
T |
9: 85,600,972 (GRCm39) |
S797R |
probably benign |
Het |
| Kif20b |
T |
A |
19: 34,936,950 (GRCm39) |
C183* |
probably null |
Het |
| Lnpep |
G |
T |
17: 17,799,433 (GRCm39) |
A74E |
probably damaging |
Het |
| Map4k1 |
A |
T |
7: 28,683,576 (GRCm39) |
|
probably benign |
Het |
| Matn1 |
A |
G |
4: 130,677,309 (GRCm39) |
R173G |
probably benign |
Het |
| Nyap1 |
A |
G |
5: 137,733,278 (GRCm39) |
I585T |
probably damaging |
Het |
| Or13a27 |
A |
T |
7: 139,925,066 (GRCm39) |
Y279N |
probably damaging |
Het |
| Or52e7 |
A |
G |
7: 104,685,151 (GRCm39) |
T249A |
probably damaging |
Het |
| Or5d39 |
G |
A |
2: 87,980,280 (GRCm39) |
P28S |
probably benign |
Het |
| Phactr2 |
A |
G |
10: 13,133,413 (GRCm39) |
V190A |
probably benign |
Het |
| Podnl1 |
G |
A |
8: 84,858,818 (GRCm39) |
V548I |
probably benign |
Het |
| Rad51c |
A |
T |
11: 87,288,579 (GRCm39) |
H201Q |
probably benign |
Het |
| Sec63 |
C |
A |
10: 42,704,937 (GRCm39) |
D730E |
probably benign |
Het |
| Smarcc2 |
A |
G |
10: 128,297,226 (GRCm39) |
I39M |
probably damaging |
Het |
| Trav2 |
A |
G |
14: 52,804,745 (GRCm39) |
|
probably benign |
Het |
| Ugt3a1 |
A |
G |
15: 9,361,569 (GRCm39) |
Y115C |
probably damaging |
Het |
|
| Other mutations in Zfp955b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00537:Zfp955b
|
APN |
17 |
33,521,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02073:Zfp955b
|
APN |
17 |
33,519,564 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02126:Zfp955b
|
APN |
17 |
33,521,238 (GRCm39) |
nonsense |
probably null |
|
|
IGL02237:Zfp955b
|
APN |
17 |
33,520,893 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02587:Zfp955b
|
APN |
17 |
33,519,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02971:Zfp955b
|
APN |
17 |
33,519,940 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03034:Zfp955b
|
APN |
17 |
33,521,142 (GRCm39) |
missense |
probably benign |
0.22 |
|
R0269:Zfp955b
|
UTSW |
17 |
33,524,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0373:Zfp955b
|
UTSW |
17 |
33,521,496 (GRCm39) |
missense |
probably benign |
|
|
R0617:Zfp955b
|
UTSW |
17 |
33,524,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0684:Zfp955b
|
UTSW |
17 |
33,521,947 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1778:Zfp955b
|
UTSW |
17 |
33,521,788 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1874:Zfp955b
|
UTSW |
17 |
33,524,427 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3893:Zfp955b
|
UTSW |
17 |
33,521,968 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3938:Zfp955b
|
UTSW |
17 |
33,524,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4082:Zfp955b
|
UTSW |
17 |
33,521,129 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4672:Zfp955b
|
UTSW |
17 |
33,524,233 (GRCm39) |
unclassified |
probably benign |
|
|
R4956:Zfp955b
|
UTSW |
17 |
33,524,209 (GRCm39) |
unclassified |
probably benign |
|
|
R4998:Zfp955b
|
UTSW |
17 |
33,524,125 (GRCm39) |
unclassified |
probably benign |
|
|
R5276:Zfp955b
|
UTSW |
17 |
33,522,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5341:Zfp955b
|
UTSW |
17 |
33,524,095 (GRCm39) |
unclassified |
probably benign |
|
|
R5558:Zfp955b
|
UTSW |
17 |
33,521,161 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6086:Zfp955b
|
UTSW |
17 |
33,521,478 (GRCm39) |
missense |
probably benign |
|
|
R6170:Zfp955b
|
UTSW |
17 |
33,521,084 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6306:Zfp955b
|
UTSW |
17 |
33,522,160 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6519:Zfp955b
|
UTSW |
17 |
33,521,051 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R9286:Zfp955b
|
UTSW |
17 |
33,521,683 (GRCm39) |
missense |
probably benign |
0.04 |
|
| Posted On |
2017-10-20 |
Incidental Mutation