Mutagenetix > Incidental Mutations

Incidental Mutation 'R7016:Gm40460'

545310

Institutional Source

Beutler Lab

Gene Symbol

Gm40460

Ensembl Gene

ENSMUSG00000110324

Gene Name

predicted gene, 40460

Synonyms

MMRRC Submission

Accession Numbers

Is this an essential gene?

Not available question?

Stock #

R7016 (G1)

Quality Score

157.526

Status

Not validated

Chromosome

Chromosomal Location

142240344-142241078 bp(-) (GRCm38)

Type of Mutation

small deletion (10 aa in frame mutation)

DNA Base Change (assembly)

CACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAG to CACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAGGAACTACAGCCTCCCTTGCAGCCCCCACAG at 142240817 bp

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000147331 (fasta)

Predicted Effect

probably benign
Transcript: ENSMUST00000211591

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.5%
20x: 98.2%

Validation Efficiency

98% (63/64)

Allele List at MGI

Other mutations in this stock

Total: 65 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1810043G02Rik	T	A	10: 77,982,956	C154S	probably benign	Het
Abcb4	T	A	5: 8,936,843	V754D	probably benign	Het
Actn1	T	A	12: 80,172,968	M710L	possibly damaging	Het
Adam1a	A	G	5: 121,521,038	F64S	probably benign	Het
Aip	G	T	19: 4,121,402	D11E	probably benign	Het
Ak7	T	A	12: 105,781,679	Y714*	probably null	Het
Amhr2	A	G	15: 102,454,364	E522G	possibly damaging	Het
Amotl1	A	G	9: 14,593,699	L108P	probably damaging	Het
Arhgef17	A	G	7: 100,878,977	S677P	probably benign	Het
Asph	T	C	4: 9,630,604		probably null	Het
Atp11b	T	C	3: 35,841,036	S908P	probably benign	Het
Atp13a3	C	A	16: 30,338,490	V903L	possibly damaging	Het
Bcam	G	A	7: 19,758,443	R576*	probably null	Het
Btbd2	A	G	10: 80,648,615	S141P	probably damaging	Het
Cacna1b	T	C	2: 24,762,848	N67S	possibly damaging	Het
Cc2d2b	A	G	19: 40,795,804	T872A	possibly damaging	Het
Ccdc24	T	A	4: 117,871,116	I144F	probably null	Het
Cep44	A	T	8: 56,544,199	F101L	possibly damaging	Het
Disp1	C	A	1: 183,087,466	R1130L	probably damaging	Het
Dnajc21	G	T	15: 10,461,407	Y152*	probably null	Het
Edem2	A	G	2: 155,716,072	F214L	possibly damaging	Het
Fam118b	G	A	9: 35,223,718	R198W	probably damaging	Het
Fam208b	A	T	13: 3,576,857	V1031E	possibly damaging	Het
Fgb	A	G	3: 83,046,064	V133A	probably benign	Het
Fsip2	A	G	2: 82,990,635	T5571A	probably benign	Het
Hjurp	CTCTGGGAGGGCTTGCTCCGGGGGCAGTGTGTCCTGTTCTTGTGCAGCCCCT	C	1: 88,266,277		probably benign	Het
Hjurp	TCTGGGAGGGCTTGCTCCGGGGGCAGTGTGTCCTGTTCTTGTGCAGCCCCTGCT	TCT	1: 88,266,278		probably benign	Het
Hnf4a	T	A	2: 163,564,273	Y277N	probably damaging	Het
Htatip2	A	G	7: 49,770,835	D143G	possibly damaging	Het
Itgae	A	G	11: 73,119,516	N611D	probably damaging	Het
Ksr1	A	T	11: 79,027,536	N515K	probably damaging	Het
Lrp1	C	A	10: 127,559,967		probably null	Het
Map3k20	T	A	2: 72,378,635	V195D	probably damaging	Het
Meox2	A	G	12: 37,109,224	S132G	probably benign	Het
Mmp1a	TG	TGG	9: 7,465,083		probably null	Het
Nell2	T	A	15: 95,229,151	N781I	possibly damaging	Het
Odf3l2	T	C	10: 79,639,956	Y258C	probably damaging	Het
Olfr106-ps	G	A	17: 37,395,203	G221D	possibly damaging	Het
Olfr513	A	G	7: 108,755,711	N285S	probably damaging	Het
Olfr535	A	G	7: 140,493,240	T201A	probably benign	Het
Olfr631	A	G	7: 103,929,530	I236V	probably benign	Het
Otoa	A	T	7: 121,147,766	Q918L	probably damaging	Het
Palld	T	G	8: 61,515,998	K1022T	probably damaging	Het
Parp8	A	T	13: 116,895,091	S362T	probably damaging	Het
Phrf1	A	G	7: 141,237,563	E95G	probably damaging	Het
Pls1	A	T	9: 95,786,941	F76I	probably damaging	Het
Pnp	T	A	14: 50,950,249		probably null	Het
Ptdss1	A	C	13: 66,972,621	M294L	probably benign	Het
Rictor	T	A	15: 6,774,880		probably null	Het
Rilp	A	G	11: 75,510,919	E175G	probably damaging	Het
Serpina16	T	A	12: 103,675,371	T32S	probably benign	Het
Sim1	C	T	10: 50,984,250	S736L	probably benign	Het
Smarcc2	T	G	10: 128,485,329		probably null	Het
Smtn	A	G	11: 3,530,368		probably null	Het
Sspo	T	A	6: 48,449,164	W98R	probably damaging	Het
St8sia3	A	T	18: 64,269,583	I98F	probably benign	Het
Taf10	A	T	7: 105,743,998		probably null	Het
Tbc1d4	T	A	14: 101,487,441	N580I	probably damaging	Het
Trim12c	A	T	7: 104,348,206	C48S		Het
Tsc22d1	C	A	14: 76,417,542	T405K	probably damaging	Het
Tubgcp5	A	G	7: 55,794,229	D2G	possibly damaging	Het
Wwc2	T	C	8: 47,847,548	E960G	unknown	Het
Yme1l1	T	A	2: 23,186,355		probably null	Het
Zbtb2	G	C	10: 4,368,646	P460R	probably damaging	Het
Zfp62	T	G	11: 49,215,937	I285S	probably damaging	Het

Other mutations in Gm40460

Allele	Source	Chr	Coord	Type	Predicted Effect
R6822:Gm40460	UTSW	7	142240713	small deletion	probably benign
R7053:Gm40460	UTSW	7	142240817	small deletion	probably benign
R7083:Gm40460	UTSW	7	142240713	small deletion	probably benign
R7087:Gm40460	UTSW	7	142240434	small deletion	probably benign
R7110:Gm40460	UTSW	7	142240817	small deletion	probably benign
R7184:Gm40460	UTSW	7	142240713	small deletion	probably benign
R7224:Gm40460	UTSW	7	142240434	small deletion	probably benign
R7367:Gm40460	UTSW	7	142240434	small deletion	probably benign
R7411:Gm40460	UTSW	7	142240817	small deletion	probably benign
R7481:Gm40460	UTSW	7	142240817	small deletion	probably benign
R7491:Gm40460	UTSW	7	142240713	small deletion	probably benign
R7553:Gm40460	UTSW	7	142240713	small deletion	probably benign
R7637:Gm40460	UTSW	7	142240713	small deletion	probably benign
R7643:Gm40460	UTSW	7	142240713	small deletion	probably benign
R7663:Gm40460	UTSW	7	142240713	small deletion	probably benign
R7785:Gm40460	UTSW	7	142240434	small deletion	probably benign
R7871:Gm40460	UTSW	7	142240817	small deletion	probably benign
R7895:Gm40460	UTSW	7	142240713	small deletion	probably benign
R8054:Gm40460	UTSW	7	142240817	small deletion	probably benign
R8355:Gm40460	UTSW	7	142240817	small deletion	probably benign
R8389:Gm40460	UTSW	7	142240434	small deletion	probably benign
R8501:Gm40460	UTSW	7	142240713	small deletion	probably benign
R8509:Gm40460	UTSW	7	142240817	small deletion	probably benign
R8736:Gm40460	UTSW	7	142240713	small deletion	probably benign
RF040:Gm40460	UTSW	7	142240817	small deletion	probably benign
Z1177:Gm40460	UTSW	7	142240772	missense	unknown
Z1177:Gm40460	UTSW	7	142240906	missense	unknown

Predicted Primers

PCR Primer
(F):5'- CTAGATTGACAGCAGCAGGG -3'
(R):5'- AGAACCATGACCTGCTGTGG -3'

Sequencing Primer
(F):5'- GCTTGCAGCAACTGGACTG -3'
(R):5'- CTGCTGCAAGCCTGTGTG -3'

Posted On

2019-05-13