Mutagenetix > Incidental Mutation

Incidental Mutation 'R4600:Dnah3'

345527

Institutional Source

Beutler Lab

Gene Symbol

Dnah3

Ensembl Gene

ENSMUSG00000052273

Gene Name

dynein, axonemal, heavy chain 3

Synonyms

Dnahc3

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

R4600 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

119521894-119694503 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 119689169 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Leucine at position 82 (M82L)

Ref Sequence

ENSEMBL: ENSMUSP00000151144 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000046993] [ENSMUST00000209154] [ENSMUST00000213149]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000046993
AA Change: M92L

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000042857
Gene: ENSMUSG00000052273
AA Change: M92L

Domain	Start	End	E-Value	Type
low complexity region	121	133	N/A	INTRINSIC
low complexity region	805	820	N/A	INTRINSIC
Pfam:DHC_N2	826	1235	3.3e-144	PFAM
AAA	1388	1527	1.59e-1	SMART
low complexity region	1594	1606	N/A	INTRINSIC
Blast:AAA	1669	1897	9e-84	BLAST
AAA	2033	2180	1.33e-3	SMART
Pfam:AAA_8	2362	2632	1.5e-63	PFAM
Pfam:MT	2644	2994	7.4e-52	PFAM
Pfam:AAA_9	3015	3240	3.5e-92	PFAM
low complexity region	3338	3349	N/A	INTRINSIC
Pfam:Dynein_heavy	3376	4079	4.4e-285	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000209154
AA Change: M92L

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

Predicted Effect

probably benign
Transcript: ENSMUST00000213149
AA Change: M82L

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000213993

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.2%
20x: 95.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]

Allele List at MGI

Other mutations in this stock

Total: 94 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2700049A03Rik	T	C	12: 71,195,037 (GRCm39)	F145L	possibly damaging	Het
Aars2	T	A	17: 45,827,847 (GRCm39)	D555E	probably damaging	Het
Ago1	C	A	4: 126,354,185 (GRCm39)	M208I	probably benign	Het
Ak7	G	A	12: 105,679,834 (GRCm39)	V123M	probably benign	Het
Amfr	A	G	8: 94,700,849 (GRCm39)	L537P	probably damaging	Het
Apob	A	G	12: 8,058,568 (GRCm39)	D2317G	probably damaging	Het
Asb6	T	A	2: 30,714,483 (GRCm39)	D209V	probably damaging	Het
AY358078	T	A	14: 52,063,532 (GRCm39)	C393S	possibly damaging	Het
Baz2a	T	A	10: 127,957,052 (GRCm39)	C932S	probably damaging	Het
Btnl10	A	G	11: 58,814,426 (GRCm39)	I369V	probably benign	Het
Ccdc66	T	C	14: 27,222,377 (GRCm39)	N122S	probably damaging	Het
Cfap96	A	T	8: 46,423,505 (GRCm39)	I69N	probably damaging	Het
Clic4	A	T	4: 134,966,300 (GRCm39)		probably null	Het
Col6a3	A	G	1: 90,709,626 (GRCm39)	S1857P	unknown	Het
Cracr2a	A	C	6: 127,580,851 (GRCm39)	D9A	probably benign	Het
Cspg4b	A	G	13: 113,455,783 (GRCm39)	R610G	possibly damaging	Het
Dcst1	T	C	3: 89,263,643 (GRCm39)	E384G	probably benign	Het
Ddx4	T	C	13: 112,748,594 (GRCm39)	K435E	probably damaging	Het
Deaf1	T	A	7: 140,890,884 (GRCm39)	T433S	possibly damaging	Het
Dnhd1	G	T	7: 105,352,851 (GRCm39)	R2668L	probably damaging	Het
Efcab6	C	T	15: 83,831,126 (GRCm39)	G596D	probably benign	Het
Ercc3	G	A	18: 32,378,624 (GRCm39)	A202T	probably benign	Het
Fam181b	C	A	7: 92,729,992 (GRCm39)	A255E	possibly damaging	Het
Fam83e	T	A	7: 45,372,924 (GRCm39)	D178E	probably benign	Het
Frem2	A	G	3: 53,455,228 (GRCm39)	L2116S	possibly damaging	Het
Gm16494	T	A	17: 47,327,723 (GRCm39)	K54*	probably null	Het
Golgb1	A	G	16: 36,738,987 (GRCm39)	D2442G	probably damaging	Het
Greb1l	G	A	18: 10,553,705 (GRCm39)	A1569T	probably damaging	Het
Grik5	C	G	7: 24,767,489 (GRCm39)	E64Q	probably damaging	Het
Gstm5	A	G	3: 107,805,302 (GRCm39)	Y130C	probably damaging	Het
Gucy2e	C	G	11: 69,126,994 (GRCm39)	A160P	possibly damaging	Het
Hydin	A	T	8: 111,293,582 (GRCm39)	T3510S	probably benign	Het
Ift70a1	T	C	2: 75,810,977 (GRCm39)	T369A	probably benign	Het
Itgb2	A	G	10: 77,381,949 (GRCm39)	I84V	probably benign	Het
Itsn1	A	G	16: 91,696,475 (GRCm39)	Q26R	probably damaging	Het
Kat6a	A	G	8: 23,429,327 (GRCm39)	S1561G	probably benign	Het
Khnyn	G	A	14: 56,124,438 (GRCm39)	V231I	probably benign	Het
Kif21b	A	G	1: 136,075,602 (GRCm39)	D243G	probably benign	Het
Klk4	T	A	7: 43,534,762 (GRCm39)	N240K	probably damaging	Het
Knl1	T	C	2: 118,901,025 (GRCm39)	S909P	possibly damaging	Het
Lamb1	A	C	12: 31,373,528 (GRCm39)	D1419A	probably benign	Het
Lin9	T	A	1: 180,508,759 (GRCm39)	V421D	probably damaging	Het
Lipt2	T	C	7: 99,809,519 (GRCm39)	L202P	probably benign	Het
Mbd5	T	G	2: 49,147,209 (GRCm39)	M473R	probably benign	Het
Mcc	A	T	18: 44,652,587 (GRCm39)	I279N	probably damaging	Het
Mcpt9	C	T	14: 56,266,049 (GRCm39)	V60M	probably damaging	Het
Mrc2	G	A	11: 105,239,257 (GRCm39)		probably null	Het
Mslnl	G	A	17: 25,961,908 (GRCm39)	V128M	probably damaging	Het
Mylk2	G	A	2: 152,759,476 (GRCm39)	V389M	probably damaging	Het
Ndufs7	T	A	10: 80,092,501 (GRCm39)	Y203*	probably null	Het
Nup160	T	A	2: 90,515,541 (GRCm39)		probably null	Het
Nup88	G	A	11: 70,860,522 (GRCm39)	R62*	probably null	Het
Or2g7	T	C	17: 38,378,853 (GRCm39)	S264P	probably damaging	Het
Or51af1	T	A	7: 103,141,788 (GRCm39)	Q99L	probably damaging	Het
Or6c207	G	A	10: 129,104,274 (GRCm39)	A306V	probably benign	Het
Or8b8	T	A	9: 37,809,622 (GRCm39)	S307R	probably benign	Het
Or8g33	A	G	9: 39,337,731 (GRCm39)	M212T	probably benign	Het
Os9	T	C	10: 126,934,223 (GRCm39)	N471S	probably benign	Het
Otof	C	T	5: 30,529,244 (GRCm39)	V1757M	probably damaging	Het
Pakap	A	T	4: 57,709,954 (GRCm39)	T300S	probably benign	Het
Pald1	T	C	10: 61,184,395 (GRCm39)	T241A	probably benign	Het
Pappa2	G	A	1: 158,642,015 (GRCm39)	S1347L	probably damaging	Het
Pccb	T	C	9: 100,916,832 (GRCm39)	T27A	probably benign	Het
Pde4dip	A	T	3: 97,603,260 (GRCm39)	V2243D	probably damaging	Het
Pkd2l2	C	A	18: 34,571,254 (GRCm39)	Q590K	probably benign	Het
Pmepa1	G	A	2: 173,070,120 (GRCm39)	P145L	possibly damaging	Het
Ppp3cb	T	C	14: 20,570,714 (GRCm39)	N339S	possibly damaging	Het
Rnf133	T	C	6: 23,649,041 (GRCm39)	E296G	possibly damaging	Het
Secisbp2l	C	T	2: 125,582,657 (GRCm39)	G933D	possibly damaging	Het
Serpinb12	T	A	1: 106,876,883 (GRCm39)	D66E	probably benign	Het
Slc35e2	T	C	4: 155,702,106 (GRCm39)	F290S	probably benign	Het
Slc46a2	C	T	4: 59,911,886 (GRCm39)	C442Y	probably damaging	Het
Slc7a1	A	G	5: 148,278,869 (GRCm39)	L301P	probably damaging	Het
Spg21	A	G	9: 65,383,257 (GRCm39)	T148A	probably benign	Het
Stox2	A	G	8: 47,645,970 (GRCm39)	S497P	probably damaging	Het
Sult1c2	C	A	17: 54,280,983 (GRCm39)	W40L	probably benign	Het
Sytl2	T	C	7: 90,024,977 (GRCm39)	S322P	probably benign	Het
Telo2	C	A	17: 25,324,122 (GRCm39)	R531L	possibly damaging	Het
Thbs3	T	C	3: 89,131,897 (GRCm39)	V719A	probably damaging	Het
Tlr9	T	A	9: 106,101,732 (GRCm39)	L341Q	probably damaging	Het
Tmprss5	A	G	9: 49,024,548 (GRCm39)	N230D	possibly damaging	Het
Tns2	C	T	15: 102,017,369 (GRCm39)	R281C	probably damaging	Het
Tpo	C	T	12: 30,148,228 (GRCm39)	V558M	probably benign	Het
Trex1	T	G	9: 108,887,352 (GRCm39)	Q213P	possibly damaging	Het
Ttc7b	G	A	12: 100,466,376 (GRCm39)	R79C	probably damaging	Het
Ugt1a6a	A	G	1: 88,066,586 (GRCm39)	K131E	probably benign	Het
Vipr1	T	A	9: 121,494,202 (GRCm39)		probably null	Het
Vmn1r22	T	C	6: 57,877,860 (GRCm39)	D39G	probably damaging	Het
Vmn2r58	A	T	7: 41,522,046 (GRCm39)	C17S	probably benign	Het
Vps41	T	C	13: 18,929,453 (GRCm39)	Y63H	probably damaging	Het
Xdh	G	T	17: 74,217,195 (GRCm39)	T691N	probably benign	Het
Zfp518b	T	C	5: 38,830,970 (GRCm39)	N345S	probably damaging	Het
Zfp536	T	A	7: 37,267,918 (GRCm39)	K499N	probably damaging	Het
Zfp963	A	T	8: 70,195,510 (GRCm39)		probably null	Het

Other mutations in Dnah3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00650:Dnah3	APN	7	119,538,128 (GRCm39)	missense	possibly damaging	0.88
IGL01095:Dnah3	APN	7	119,550,820 (GRCm39)	missense	probably benign	0.02
IGL01329:Dnah3	APN	7	119,622,164 (GRCm39)	missense	probably damaging	1.00
IGL01380:Dnah3	APN	7	119,525,787 (GRCm39)	missense	probably damaging	1.00
IGL01410:Dnah3	APN	7	119,566,943 (GRCm39)	missense	possibly damaging	0.91
IGL01487:Dnah3	APN	7	119,564,753 (GRCm39)	nonsense	probably null
IGL01843:Dnah3	APN	7	119,542,798 (GRCm39)	missense	probably benign	0.12
IGL01929:Dnah3	APN	7	119,550,874 (GRCm39)	nonsense	probably null
IGL01994:Dnah3	APN	7	119,550,437 (GRCm39)	missense	possibly damaging	0.58
IGL02115:Dnah3	APN	7	119,628,277 (GRCm39)	missense	probably damaging	1.00
IGL02273:Dnah3	APN	7	119,550,494 (GRCm39)	missense	probably damaging	1.00
IGL02299:Dnah3	APN	7	119,566,802 (GRCm39)	missense	probably benign	0.39
IGL02421:Dnah3	APN	7	119,550,215 (GRCm39)	missense	possibly damaging	0.87
IGL02514:Dnah3	APN	7	119,565,470 (GRCm39)	missense	probably damaging	1.00
IGL02596:Dnah3	APN	7	119,538,137 (GRCm39)	missense	probably benign	0.19
IGL02716:Dnah3	APN	7	119,536,246 (GRCm39)	missense	probably damaging	0.97
IGL02738:Dnah3	APN	7	119,564,720 (GRCm39)	missense	probably benign
IGL03404:Dnah3	APN	7	119,538,200 (GRCm39)	missense	probably damaging	1.00
R0964_Dnah3_480	UTSW	7	119,551,962 (GRCm39)	splice site	probably benign
R1778_Dnah3_238	UTSW	7	119,677,625 (GRCm39)	missense	probably damaging	1.00
R4658_Dnah3_599	UTSW	7	119,549,874 (GRCm39)	missense	probably damaging	1.00
BB004:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
BB014:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
R0011:Dnah3	UTSW	7	119,618,924 (GRCm39)	missense	probably damaging	1.00
R0195:Dnah3	UTSW	7	119,676,998 (GRCm39)	critical splice donor site	probably null
R0241:Dnah3	UTSW	7	119,521,953 (GRCm39)	missense	probably damaging	1.00
R0241:Dnah3	UTSW	7	119,521,953 (GRCm39)	missense	probably damaging	1.00
R0312:Dnah3	UTSW	7	119,644,882 (GRCm39)	missense	probably damaging	1.00
R0316:Dnah3	UTSW	7	119,564,882 (GRCm39)	missense	possibly damaging	0.94
R0370:Dnah3	UTSW	7	119,685,943 (GRCm39)	missense	possibly damaging	0.91
R0426:Dnah3	UTSW	7	119,542,795 (GRCm39)	missense	probably benign	0.11
R0525:Dnah3	UTSW	7	119,527,977 (GRCm39)	missense	probably damaging	1.00
R0625:Dnah3	UTSW	7	119,671,110 (GRCm39)	missense	possibly damaging	0.68
R0627:Dnah3	UTSW	7	119,620,138 (GRCm39)	missense	probably damaging	1.00
R0632:Dnah3	UTSW	7	119,567,128 (GRCm39)	missense	probably benign	0.11
R0928:Dnah3	UTSW	7	119,629,274 (GRCm39)	missense	probably damaging	1.00
R0964:Dnah3	UTSW	7	119,551,962 (GRCm39)	splice site	probably benign
R0972:Dnah3	UTSW	7	119,634,563 (GRCm39)	splice site	probably null
R1066:Dnah3	UTSW	7	119,660,232 (GRCm39)	missense	probably damaging	1.00
R1082:Dnah3	UTSW	7	119,677,668 (GRCm39)	missense	probably damaging	1.00
R1127:Dnah3	UTSW	7	119,522,253 (GRCm39)	missense	probably damaging	1.00
R1132:Dnah3	UTSW	7	119,538,227 (GRCm39)	missense	possibly damaging	0.50
R1222:Dnah3	UTSW	7	119,689,899 (GRCm39)	missense	probably benign	0.28
R1420:Dnah3	UTSW	7	119,551,202 (GRCm39)	missense	probably damaging	0.99
R1456:Dnah3	UTSW	7	119,646,853 (GRCm39)	missense	probably damaging	1.00
R1472:Dnah3	UTSW	7	119,670,181 (GRCm39)	missense	probably benign	0.12
R1617:Dnah3	UTSW	7	119,689,169 (GRCm39)	missense	probably benign	0.01
R1624:Dnah3	UTSW	7	119,618,918 (GRCm39)	missense	probably damaging	0.99
R1654:Dnah3	UTSW	7	119,525,672 (GRCm39)	missense	probably damaging	1.00
R1673:Dnah3	UTSW	7	119,570,402 (GRCm39)	nonsense	probably null
R1677:Dnah3	UTSW	7	119,527,963 (GRCm39)	missense	probably damaging	1.00
R1687:Dnah3	UTSW	7	119,645,009 (GRCm39)	splice site	probably null
R1711:Dnah3	UTSW	7	119,677,794 (GRCm39)	missense	probably damaging	1.00
R1738:Dnah3	UTSW	7	119,634,582 (GRCm39)	missense	probably damaging	1.00
R1778:Dnah3	UTSW	7	119,677,625 (GRCm39)	missense	probably damaging	1.00
R1866:Dnah3	UTSW	7	119,528,079 (GRCm39)	splice site	probably null
R1883:Dnah3	UTSW	7	119,677,142 (GRCm39)	missense	probably benign	0.06
R1894:Dnah3	UTSW	7	119,685,557 (GRCm39)	missense	probably benign	0.05
R1929:Dnah3	UTSW	7	119,574,352 (GRCm39)	missense	probably benign	0.10
R1988:Dnah3	UTSW	7	119,567,182 (GRCm39)	missense	probably damaging	0.99
R1988:Dnah3	UTSW	7	119,566,793 (GRCm39)	missense	possibly damaging	0.92
R2010:Dnah3	UTSW	7	119,694,400 (GRCm39)	start codon destroyed	probably benign	0.00
R2022:Dnah3	UTSW	7	119,550,465 (GRCm39)	missense	probably damaging	1.00
R2026:Dnah3	UTSW	7	119,638,629 (GRCm39)	missense	probably damaging	1.00
R2063:Dnah3	UTSW	7	119,551,132 (GRCm39)	missense	probably damaging	0.96
R2131:Dnah3	UTSW	7	119,566,982 (GRCm39)	missense	possibly damaging	0.93
R2152:Dnah3	UTSW	7	119,551,236 (GRCm39)	missense	probably benign	0.02
R2199:Dnah3	UTSW	7	119,550,792 (GRCm39)	missense	possibly damaging	0.89
R2271:Dnah3	UTSW	7	119,574,352 (GRCm39)	missense	probably benign	0.10
R2350:Dnah3	UTSW	7	119,645,011 (GRCm39)	splice site	probably null
R2567:Dnah3	UTSW	7	119,551,920 (GRCm39)	missense	possibly damaging	0.83
R2848:Dnah3	UTSW	7	119,567,161 (GRCm39)	missense	probably benign	0.01
R2902:Dnah3	UTSW	7	119,550,722 (GRCm39)	missense	possibly damaging	0.61
R2926:Dnah3	UTSW	7	119,550,338 (GRCm39)	missense	probably damaging	1.00
R2944:Dnah3	UTSW	7	119,550,333 (GRCm39)	missense	probably damaging	1.00
R3022:Dnah3	UTSW	7	119,677,704 (GRCm39)	missense	possibly damaging	0.93
R3401:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3402:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3403:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3919:Dnah3	UTSW	7	119,550,303 (GRCm39)	missense	probably damaging	1.00
R3972:Dnah3	UTSW	7	119,685,943 (GRCm39)	missense	probably damaging	0.99
R4162:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4184:Dnah3	UTSW	7	119,682,516 (GRCm39)	missense	probably damaging	1.00
R4198:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4199:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4200:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4239:Dnah3	UTSW	7	119,628,248 (GRCm39)	nonsense	probably null
R4478:Dnah3	UTSW	7	119,671,086 (GRCm39)	missense	probably benign	0.00
R4579:Dnah3	UTSW	7	119,608,554 (GRCm39)	missense	probably damaging	1.00
R4649:Dnah3	UTSW	7	119,646,921 (GRCm39)	missense	probably damaging	1.00
R4658:Dnah3	UTSW	7	119,549,874 (GRCm39)	missense	probably damaging	1.00
R4728:Dnah3	UTSW	7	119,658,589 (GRCm39)	missense	probably damaging	0.99
R4739:Dnah3	UTSW	7	119,677,169 (GRCm39)	missense	possibly damaging	0.54
R4758:Dnah3	UTSW	7	119,678,629 (GRCm39)	missense	probably benign	0.00
R4785:Dnah3	UTSW	7	119,567,047 (GRCm39)	missense	probably benign	0.29
R4789:Dnah3	UTSW	7	119,610,295 (GRCm39)	missense	probably damaging	1.00
R4930:Dnah3	UTSW	7	119,550,904 (GRCm39)	nonsense	probably null
R4935:Dnah3	UTSW	7	119,615,700 (GRCm39)	nonsense	probably null
R4946:Dnah3	UTSW	7	119,530,783 (GRCm39)	missense	probably damaging	1.00
R4981:Dnah3	UTSW	7	119,555,424 (GRCm39)	missense	probably benign	0.03
R4984:Dnah3	UTSW	7	119,528,002 (GRCm39)	missense	probably benign	0.04
R5025:Dnah3	UTSW	7	119,671,128 (GRCm39)	missense	probably benign	0.02
R5046:Dnah3	UTSW	7	119,550,803 (GRCm39)	missense	probably damaging	1.00
R5056:Dnah3	UTSW	7	119,620,169 (GRCm39)	missense	probably damaging	1.00
R5068:Dnah3	UTSW	7	119,632,013 (GRCm39)	missense	probably benign
R5069:Dnah3	UTSW	7	119,632,013 (GRCm39)	missense	probably benign
R5154:Dnah3	UTSW	7	119,551,642 (GRCm39)	missense	probably damaging	1.00
R5208:Dnah3	UTSW	7	119,631,861 (GRCm39)	missense	probably damaging	1.00
R5323:Dnah3	UTSW	7	119,620,234 (GRCm39)	missense	probably damaging	1.00
R5330:Dnah3	UTSW	7	119,542,871 (GRCm39)	missense	probably benign	0.00
R5385:Dnah3	UTSW	7	119,524,126 (GRCm39)	missense	probably damaging	1.00
R5391:Dnah3	UTSW	7	119,689,299 (GRCm39)	missense	probably benign	0.02
R5564:Dnah3	UTSW	7	119,570,689 (GRCm39)	critical splice donor site	probably null
R5594:Dnah3	UTSW	7	119,570,844 (GRCm39)	missense	possibly damaging	0.89
R5610:Dnah3	UTSW	7	119,538,288 (GRCm39)	splice site	probably null
R5673:Dnah3	UTSW	7	119,550,812 (GRCm39)	missense	possibly damaging	0.91
R5678:Dnah3	UTSW	7	119,677,074 (GRCm39)	missense	probably benign	0.00
R5737:Dnah3	UTSW	7	119,658,421 (GRCm39)	missense	probably benign	0.03
R5766:Dnah3	UTSW	7	119,577,445 (GRCm39)	missense	probably damaging	1.00
R5769:Dnah3	UTSW	7	119,689,175 (GRCm39)	nonsense	probably null
R5789:Dnah3	UTSW	7	119,542,822 (GRCm39)	missense	possibly damaging	0.70
R5791:Dnah3	UTSW	7	119,530,696 (GRCm39)	missense	probably benign	0.00
R5841:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5843:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5844:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5846:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5851:Dnah3	UTSW	7	119,638,585 (GRCm39)	missense	possibly damaging	0.51
R5853:Dnah3	UTSW	7	119,538,056 (GRCm39)	missense	probably damaging	1.00
R5857:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5865:Dnah3	UTSW	7	119,574,331 (GRCm39)	missense	probably benign	0.00
R5885:Dnah3	UTSW	7	119,668,927 (GRCm39)	missense	probably benign	0.10
R5898:Dnah3	UTSW	7	119,677,724 (GRCm39)	missense	probably benign	0.37
R5917:Dnah3	UTSW	7	119,615,749 (GRCm39)	missense	probably damaging	1.00
R5964:Dnah3	UTSW	7	119,522,103 (GRCm39)	missense	probably benign	0.00
R5990:Dnah3	UTSW	7	119,672,764 (GRCm39)	missense	probably benign
R6004:Dnah3	UTSW	7	119,685,520 (GRCm39)	missense	probably benign	0.10
R6033:Dnah3	UTSW	7	119,670,870 (GRCm39)	missense	probably benign	0.00
R6033:Dnah3	UTSW	7	119,670,870 (GRCm39)	missense	probably benign	0.00
R6045:Dnah3	UTSW	7	119,566,745 (GRCm39)	missense	probably damaging	0.99
R6056:Dnah3	UTSW	7	119,629,254 (GRCm39)	missense	probably damaging	1.00
R6133:Dnah3	UTSW	7	119,685,469 (GRCm39)	missense	probably benign	0.10
R6229:Dnah3	UTSW	7	119,564,711 (GRCm39)	missense	probably benign	0.11
R6237:Dnah3	UTSW	7	119,608,607 (GRCm39)	missense	probably damaging	1.00
R6333:Dnah3	UTSW	7	119,653,856 (GRCm39)	missense	probably damaging	1.00
R6408:Dnah3	UTSW	7	119,522,191 (GRCm39)	splice site	probably null
R6447:Dnah3	UTSW	7	119,522,277 (GRCm39)	missense	probably benign	0.12
R6606:Dnah3	UTSW	7	119,660,179 (GRCm39)	missense	probably benign	0.02
R6666:Dnah3	UTSW	7	119,670,172 (GRCm39)	missense	probably benign	0.16
R6733:Dnah3	UTSW	7	119,522,197 (GRCm39)	missense	probably benign	0.22
R6815:Dnah3	UTSW	7	119,570,950 (GRCm39)	missense	probably benign
R6882:Dnah3	UTSW	7	119,570,407 (GRCm39)	missense	possibly damaging	0.95
R6934:Dnah3	UTSW	7	119,653,824 (GRCm39)	critical splice donor site	probably null
R6966:Dnah3	UTSW	7	119,631,977 (GRCm39)	missense	probably damaging	1.00
R7025:Dnah3	UTSW	7	119,629,233 (GRCm39)	missense	possibly damaging	0.90
R7207:Dnah3	UTSW	7	119,570,312 (GRCm39)	missense	probably damaging	1.00
R7214:Dnah3	UTSW	7	119,521,965 (GRCm39)	missense	probably damaging	1.00
R7222:Dnah3	UTSW	7	119,670,746 (GRCm39)	missense	probably benign	0.00
R7235:Dnah3	UTSW	7	119,631,893 (GRCm39)	missense	probably damaging	1.00
R7241:Dnah3	UTSW	7	119,542,856 (GRCm39)	missense	probably benign	0.03
R7313:Dnah3	UTSW	7	119,580,567 (GRCm39)	missense	probably benign	0.39
R7342:Dnah3	UTSW	7	119,629,208 (GRCm39)	missense	probably damaging	1.00
R7368:Dnah3	UTSW	7	119,628,239 (GRCm39)	missense	probably benign
R7375:Dnah3	UTSW	7	119,550,900 (GRCm39)	missense	probably damaging	1.00
R7395:Dnah3	UTSW	7	119,660,183 (GRCm39)	missense	probably benign	0.00
R7395:Dnah3	UTSW	7	119,565,474 (GRCm39)	missense
R7431:Dnah3	UTSW	7	119,650,967 (GRCm39)	missense	probably damaging	1.00
R7499:Dnah3	UTSW	7	119,660,135 (GRCm39)	missense	probably damaging	0.99
R7515:Dnah3	UTSW	7	119,672,815 (GRCm39)	missense	probably benign	0.21
R7564:Dnah3	UTSW	7	119,570,817 (GRCm39)	missense	probably benign
R7618:Dnah3	UTSW	7	119,577,601 (GRCm39)	missense	probably damaging	0.97
R7697:Dnah3	UTSW	7	119,566,657 (GRCm39)	missense
R7728:Dnah3	UTSW	7	119,538,051 (GRCm39)	missense	probably damaging	1.00
R7757:Dnah3	UTSW	7	119,570,438 (GRCm39)	splice site	probably null
R7757:Dnah3	UTSW	7	119,670,793 (GRCm39)	missense	probably benign
R7774:Dnah3	UTSW	7	119,550,975 (GRCm39)	nonsense	probably null
R7804:Dnah3	UTSW	7	119,610,235 (GRCm39)	missense	probably damaging	1.00
R7804:Dnah3	UTSW	7	119,551,841 (GRCm39)	missense	probably damaging	1.00
R7857:Dnah3	UTSW	7	119,550,927 (GRCm39)	missense	probably damaging	1.00
R7871:Dnah3	UTSW	7	119,566,775 (GRCm39)	missense
R7903:Dnah3	UTSW	7	119,641,351 (GRCm39)	missense	probably damaging	1.00
R7927:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
R7989:Dnah3	UTSW	7	119,677,012 (GRCm39)	missense	probably benign
R8142:Dnah3	UTSW	7	119,660,189 (GRCm39)	missense	probably benign	0.00
R8164:Dnah3	UTSW	7	119,566,837 (GRCm39)	missense	probably damaging	1.00
R8237:Dnah3	UTSW	7	119,525,636 (GRCm39)	missense	probably benign	0.01
R8313:Dnah3	UTSW	7	119,550,375 (GRCm39)	missense	probably benign	0.38
R8338:Dnah3	UTSW	7	119,671,104 (GRCm39)	missense	probably benign	0.01
R8355:Dnah3	UTSW	7	119,551,431 (GRCm39)	missense	probably damaging	1.00
R8408:Dnah3	UTSW	7	119,551,728 (GRCm39)	missense	probably damaging	1.00
R8411:Dnah3	UTSW	7	119,610,253 (GRCm39)	missense	probably damaging	1.00
R8455:Dnah3	UTSW	7	119,551,431 (GRCm39)	missense	probably damaging	1.00
R8483:Dnah3	UTSW	7	119,536,253 (GRCm39)	missense	probably benign	0.00
R8531:Dnah3	UTSW	7	119,550,591 (GRCm39)	missense	probably damaging	1.00
R8885:Dnah3	UTSW	7	119,561,375 (GRCm39)	missense
R8912:Dnah3	UTSW	7	119,689,869 (GRCm39)	missense	probably benign	0.06
R8966:Dnah3	UTSW	7	119,549,881 (GRCm39)	nonsense	probably null
R8982:Dnah3	UTSW	7	119,536,294 (GRCm39)	missense	probably damaging	1.00
R9043:Dnah3	UTSW	7	119,551,272 (GRCm39)	missense	probably benign
R9053:Dnah3	UTSW	7	119,618,987 (GRCm39)	missense	possibly damaging	0.67
R9059:Dnah3	UTSW	7	119,684,368 (GRCm39)	missense	probably benign	0.01
R9182:Dnah3	UTSW	7	119,684,351 (GRCm39)	missense	probably damaging	0.98
R9365:Dnah3	UTSW	7	119,566,859 (GRCm39)	missense
R9383:Dnah3	UTSW	7	119,646,819 (GRCm39)	missense	probably benign	0.23
R9430:Dnah3	UTSW	7	119,628,205 (GRCm39)	missense	probably damaging	1.00
R9449:Dnah3	UTSW	7	119,551,473 (GRCm39)	missense	probably benign	0.12
R9462:Dnah3	UTSW	7	119,551,523 (GRCm39)	missense	probably benign	0.05
R9505:Dnah3	UTSW	7	119,644,912 (GRCm39)	missense	probably damaging	1.00
R9559:Dnah3	UTSW	7	119,650,951 (GRCm39)	missense	probably benign	0.07
R9562:Dnah3	UTSW	7	119,610,114 (GRCm39)	missense	probably benign	0.05
R9565:Dnah3	UTSW	7	119,610,114 (GRCm39)	missense	probably benign	0.05
R9609:Dnah3	UTSW	7	119,670,236 (GRCm39)	missense	probably damaging	0.98
R9622:Dnah3	UTSW	7	119,561,356 (GRCm39)	missense
R9633:Dnah3	UTSW	7	119,550,216 (GRCm39)	missense	probably benign
R9654:Dnah3	UTSW	7	119,641,396 (GRCm39)	nonsense	probably null
R9665:Dnah3	UTSW	7	119,644,981 (GRCm39)	missense	probably benign	0.01
R9681:Dnah3	UTSW	7	119,677,611 (GRCm39)	missense	probably benign	0.04
R9717:Dnah3	UTSW	7	119,574,299 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnah3	UTSW	7	119,610,096 (GRCm39)	missense	probably null	1.00
Z1088:Dnah3	UTSW	7	119,685,520 (GRCm39)	missense	probably benign	0.00
Z1176:Dnah3	UTSW	7	119,567,026 (GRCm39)	missense
Z1177:Dnah3	UTSW	7	119,607,085 (GRCm39)	missense	probably benign
Z1177:Dnah3	UTSW	7	119,567,124 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- AACACAAGTTTCTAGGTGTTGTGG -3'
(R):5'- AACTTGGTCTCAGTGGGAGC -3'

Sequencing Primer
(F):5'- GAGATCTTGAGCTTGAACTACGC -3'
(R):5'- AGGCTCACTGTCTCTGACTATG -3'

Posted On

2015-09-25