Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00678:Ifi213'

13711

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ifi213

Ensembl Gene

ENSMUSG00000073491

Gene Name

interferon activated gene 213

Synonyms

Pyr-A, Pydc4, E030037K03Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.060) question?

Stock #

IGL00678

Quality Score

Status

Chromosome

Chromosomal Location

173393849-173426840 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 173421619 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000136238 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000097462] [ENSMUST00000150649] [ENSMUST00000180215]

AlphaFold

D3Z5G0

Predicted Effect

probably benign
Transcript: ENSMUST00000097462

SMART Domains

Protein: ENSMUSP00000095070
Gene: ENSMUSG00000073491

Domain	Start	End	E-Value	Type
PYRIN	10	88	3.71e-20	SMART
low complexity region	101	112	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000150649

SMART Domains

Protein: ENSMUSP00000117222
Gene: ENSMUSG00000073491

Domain	Start	End	E-Value	Type
PYRIN	10	88	3.71e-20	SMART
low complexity region	101	112	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000180215

SMART Domains

Protein: ENSMUSP00000136238
Gene: ENSMUSG00000073491

Domain	Start	End	E-Value	Type
PYRIN	10	88	3.71e-20	SMART
low complexity region	101	112	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 14 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Baz2b	T	C	2: 59,836,527 (GRCm39)	E2G	unknown	Het
Bbs2	T	A	8: 94,815,795 (GRCm39)		probably null	Het
Cdk14	T	C	5: 5,299,237 (GRCm39)		probably benign	Het
Cubn	A	T	2: 13,472,521 (GRCm39)	I477N	possibly damaging	Het
Dtl	A	C	1: 191,278,738 (GRCm39)		probably null	Het
Ercc6l2	T	A	13: 63,992,427 (GRCm39)	V292E	probably damaging	Het
Eri3	A	G	4: 117,422,088 (GRCm39)	H122R	probably benign	Het
Glrx3	T	A	7: 137,054,442 (GRCm39)	V75D	probably damaging	Het
Ppp1cb	T	A	5: 32,642,682 (GRCm39)		probably benign	Het
Rb1cc1	A	G	1: 6,304,309 (GRCm39)	T66A	probably damaging	Het
Slco6d1	A	G	1: 98,424,069 (GRCm39)	S574G	probably benign	Het
Tas2r136	A	T	6: 132,754,161 (GRCm39)	L322Q	probably damaging	Het
Tead1	A	G	7: 112,441,087 (GRCm39)		probably null	Het
Tsfm	G	A	10: 126,864,311 (GRCm39)	Q135*	probably null	Het

Other mutations in Ifi213

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00908:Ifi213	APN	1	173,422,649 (GRCm39)	missense	probably damaging	1.00
IGL00964:Ifi213	APN	1	173,421,518 (GRCm39)	missense	possibly damaging	0.91
IGL02217:Ifi213	APN	1	173,422,598 (GRCm39)	missense	possibly damaging	0.91
R0709:Ifi213	UTSW	1	173,417,366 (GRCm39)	missense	possibly damaging	0.70
R1518:Ifi213	UTSW	1	173,417,229 (GRCm39)	missense	probably damaging	0.99
R1559:Ifi213	UTSW	1	173,394,784 (GRCm39)	missense	probably benign	0.18
R1822:Ifi213	UTSW	1	173,417,408 (GRCm39)	missense	probably damaging	0.99
R1839:Ifi213	UTSW	1	173,417,166 (GRCm39)	missense	probably damaging	0.98
R1989:Ifi213	UTSW	1	173,396,374 (GRCm39)	critical splice donor site	probably null
R2108:Ifi213	UTSW	1	173,396,668 (GRCm39)	critical splice acceptor site	probably null
R2696:Ifi213	UTSW	1	173,417,590 (GRCm39)	missense	probably benign
R3890:Ifi213	UTSW	1	173,394,822 (GRCm39)	missense	probably benign	0.33
R4544:Ifi213	UTSW	1	173,409,693 (GRCm39)	splice site	probably null
R4611:Ifi213	UTSW	1	173,417,480 (GRCm39)	missense	possibly damaging	0.91
R4689:Ifi213	UTSW	1	173,417,986 (GRCm39)	missense	possibly damaging	0.92
R4710:Ifi213	UTSW	1	173,394,738 (GRCm39)	utr 3 prime	probably benign
R5126:Ifi213	UTSW	1	173,417,581 (GRCm39)	missense	possibly damaging	0.85
R5472:Ifi213	UTSW	1	173,394,838 (GRCm39)	splice site	probably null
R5625:Ifi213	UTSW	1	173,396,629 (GRCm39)	missense	possibly damaging	0.73
R5789:Ifi213	UTSW	1	173,396,360 (GRCm39)	splice site	probably benign
R5898:Ifi213	UTSW	1	173,396,545 (GRCm39)	missense	probably benign	0.01
R6025:Ifi213	UTSW	1	173,422,800 (GRCm39)	missense	probably damaging	0.99
R6149:Ifi213	UTSW	1	173,421,581 (GRCm39)	missense	probably benign	0.18
R6348:Ifi213	UTSW	1	173,417,848 (GRCm39)	missense	possibly damaging	0.46
R6564:Ifi213	UTSW	1	173,422,862 (GRCm39)	start codon destroyed	probably null	0.06
R7254:Ifi213	UTSW	1	173,421,529 (GRCm39)	missense	probably damaging	0.98
R7292:Ifi213	UTSW	1	173,422,691 (GRCm39)	missense	probably damaging	0.99
R7752:Ifi213	UTSW	1	173,394,784 (GRCm39)	missense	probably benign	0.18
R7901:Ifi213	UTSW	1	173,394,784 (GRCm39)	missense	probably benign	0.18
R8100:Ifi213	UTSW	1	173,422,748 (GRCm39)	missense	probably damaging	1.00
R8352:Ifi213	UTSW	1	173,422,835 (GRCm39)	missense	possibly damaging	0.92
R8425:Ifi213	UTSW	1	173,417,426 (GRCm39)	missense	probably benign
R8452:Ifi213	UTSW	1	173,422,835 (GRCm39)	missense	possibly damaging	0.92
R9357:Ifi213	UTSW	1	173,396,392 (GRCm39)	missense	probably benign	0.01
RF010:Ifi213	UTSW	1	173,409,719 (GRCm39)	missense	probably damaging	0.98

Posted On

2012-12-06