Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02607:Tex2'

300313

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tex2

Ensembl Gene

ENSMUSG00000040548

Gene Name

testis expressed gene 2

Synonyms

Def-5, Taz4, 4930568E07Rik

Accession Numbers

Is this an essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02607

Quality Score

Status

Chromosome

Chromosomal Location

106502147-106613423 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 106546747 bp

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 699 (E699G)

Ref Sequence

ENSEMBL: ENSMUSP00000099359 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000042780] [ENSMUST00000103070]

Predicted Effect

unknown
Transcript: ENSMUST00000042780
AA Change: E699G

SMART Domains

Protein: ENSMUSP00000041985
Gene: ENSMUSG00000040548
AA Change: E699G

Domain	Start	End	E-Value	Type
low complexity region	119	186	N/A	INTRINSIC
low complexity region	319	341	N/A	INTRINSIC
low complexity region	346	360	N/A	INTRINSIC
transmembrane domain	473	492	N/A	INTRINSIC
transmembrane domain	494	516	N/A	INTRINSIC
PH	543	712	5.05e-1	SMART
low complexity region	732	752	N/A	INTRINSIC
low complexity region	811	823	N/A	INTRINSIC
low complexity region	946	965	N/A	INTRINSIC
low complexity region	1003	1016	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000103070
AA Change: E699G

SMART Domains

Protein: ENSMUSP00000099359
Gene: ENSMUSG00000040548
AA Change: E699G

Domain	Start	End	E-Value	Type
low complexity region	119	186	N/A	INTRINSIC
low complexity region	319	341	N/A	INTRINSIC
low complexity region	346	360	N/A	INTRINSIC
transmembrane domain	473	492	N/A	INTRINSIC
transmembrane domain	494	516	N/A	INTRINSIC
PH	543	712	5.05e-1	SMART
low complexity region	732	752	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000207249
AA Change: E201G

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 25 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110004E09Rik	G	A	16: 90,929,947	T98M	probably damaging	Het
Abca17	C	T	17: 24,327,705	W307*	probably null	Het
Cit	A	G	5: 115,859,209	I84V	probably benign	Het
Cltc	T	C	11: 86,706,714	D1132G	probably benign	Het
Cobll1	A	T	2: 65,151,085	S54T	probably damaging	Het
Dcstamp	A	G	15: 39,754,584	R130G	possibly damaging	Het
Dennd4a	A	G	9: 64,862,327	M439V	probably damaging	Het
Dnajc15	T	A	14: 77,840,216	I110F	probably damaging	Het
Dock1	T	C	7: 134,851,513	F824L	probably benign	Het
Eml2	A	G	7: 19,206,111	H617R	probably damaging	Het
Fgd6	A	T	10: 94,044,448	Q388L	possibly damaging	Het
Fkbp4	A	T	6: 128,434,470		probably benign	Het
Fmnl3	A	T	15: 99,324,772	L431Q	probably damaging	Het
Gng8	T	C	7: 16,894,934		probably benign	Het
Hmcn1	T	A	1: 150,744,995	I1155F	possibly damaging	Het
Muc4	G	T	16: 32,775,819	C3135F	possibly damaging	Het
Mycbp2	C	T	14: 103,285,273	G685D	probably damaging	Het
Olfr1389	T	C	11: 49,430,512	F12S	probably damaging	Het
Pcdhb8	A	T	18: 37,357,581	I771F	probably benign	Het
Pkn2	A	G	3: 142,794,101		probably null	Het
Rrn3	G	T	16: 13,806,563	V420L	possibly damaging	Het
Samm50	A	T	15: 84,207,838	Y338F	probably benign	Het
Slc2a7	C	T	4: 150,154,705	T129I	probably benign	Het
Tbc1d8	T	C	1: 39,379,511	I806V	probably benign	Het
Vmn2r85	T	C	10: 130,426,421	K150E	possibly damaging	Het

Other mutations in Tex2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00090:Tex2	APN	11	106568535	missense	probably damaging	1.00
IGL01380:Tex2	APN	11	106544315	nonsense	probably null
IGL02680:Tex2	APN	11	106568232	unclassified	probably benign
IGL02699:Tex2	APN	11	106568433	missense	possibly damaging	0.53
IGL03187:Tex2	APN	11	106568077	unclassified	probably benign
IGL03398:Tex2	APN	11	106568272	missense	probably damaging	1.00
R0242:Tex2	UTSW	11	106519955	nonsense	probably null
R0242:Tex2	UTSW	11	106519955	nonsense	probably null
R1085:Tex2	UTSW	11	106568487	missense	probably damaging	0.98
R1491:Tex2	UTSW	11	106503640	missense	possibly damaging	0.72
R1664:Tex2	UTSW	11	106567782	unclassified	probably benign
R1794:Tex2	UTSW	11	106567902	unclassified	probably benign
R1855:Tex2	UTSW	11	106546876	missense	possibly damaging	0.87
R2077:Tex2	UTSW	11	106506864	splice site	probably null
R2151:Tex2	UTSW	11	106567335	unclassified	probably benign
R2175:Tex2	UTSW	11	106503687	missense	unknown
R2984:Tex2	UTSW	11	106546663	critical splice donor site	probably null
R3156:Tex2	UTSW	11	106533869	critical splice donor site	probably null
R3722:Tex2	UTSW	11	106546740	nonsense	probably null
R3724:Tex2	UTSW	11	106529330	missense	unknown
R3770:Tex2	UTSW	11	106544252	missense	unknown
R3771:Tex2	UTSW	11	106546894	missense	unknown
R3813:Tex2	UTSW	11	106511944	missense	unknown
R3947:Tex2	UTSW	11	106520003	missense	unknown
R4206:Tex2	UTSW	11	106567572	unclassified	probably benign
R4342:Tex2	UTSW	11	106567006	unclassified	probably benign
R4554:Tex2	UTSW	11	106544386	missense	unknown
R4896:Tex2	UTSW	11	106568404	missense	probably damaging	1.00
R5207:Tex2	UTSW	11	106546840	missense	unknown
R5249:Tex2	UTSW	11	106546789	missense	unknown
R5257:Tex2	UTSW	11	106567759	unclassified	probably benign
R5258:Tex2	UTSW	11	106567759	unclassified	probably benign
R5278:Tex2	UTSW	11	106567813	missense	probably benign	0.34
R5702:Tex2	UTSW	11	106544395	missense	possibly damaging	0.58
R5835:Tex2	UTSW	11	106519913	missense	unknown
R6150:Tex2	UTSW	11	106567080	missense	probably benign	0.34
R6785:Tex2	UTSW	11	106533950	missense	probably damaging	1.00
R6879:Tex2	UTSW	11	106534010	missense	unknown
R7038:Tex2	UTSW	11	106511900	critical splice donor site	probably null
R7117:Tex2	UTSW	11	106544245	missense	unknown
R7336:Tex2	UTSW	11	106548859	missense	unknown
R7568:Tex2	UTSW	11	106548736	missense	unknown
R7622:Tex2	UTSW	11	106546895	missense	unknown
R8228:Tex2	UTSW	11	106567171	missense	probably benign	0.34
R8407:Tex2	UTSW	11	106568395	missense	probably damaging	1.00
R8807:Tex2	UTSW	11	106544368	missense	unknown
R8807:Tex2	UTSW	11	106567588	missense	unknown
T0970:Tex2	UTSW	11	106546946	missense	unknown
Z1177:Tex2	UTSW	11	106534008	missense	unknown

Posted On

2015-04-16