Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02984:Mfsd4b3-ps'

406666

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Mfsd4b3-ps

Ensembl Gene

ENSMUSG00000071335

Gene Name

major facilitator superfamily domain containing 4B3, pseudogene

Synonyms

G630090E17Rik, Mfsd4b3

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.096) question?

Stock #

IGL02984 (G1)

Quality Score

Status

Chromosome

Chromosomal Location

39822919-39836086 bp(-) (GRCm39)

Type of Mutation

utr 3 prime

DNA Base Change (assembly)

G to A at 39823184 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000093420 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000095749]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000095749

SMART Domains

Protein: ENSMUSP00000093420
Gene: ENSMUSG00000071335

Domain	Start	End	E-Value	Type
transmembrane domain	2	21	N/A	INTRINSIC
transmembrane domain	31	53	N/A	INTRINSIC
transmembrane domain	66	88	N/A	INTRINSIC
transmembrane domain	125	147	N/A	INTRINSIC
transmembrane domain	173	195	N/A	INTRINSIC
transmembrane domain	236	258	N/A	INTRINSIC
transmembrane domain	265	287	N/A	INTRINSIC
transmembrane domain	297	319	N/A	INTRINSIC
transmembrane domain	326	348	N/A	INTRINSIC

Coding Region Coverage

1x: 0.0%
3x: 0.0%
10x: 0.0%
20x: 0.0%

Validation Efficiency

100% (43/43)

Allele List at MGI

Other mutations in this stock

Total: 36 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310003L06Rik	T	A	5: 88,120,662 (GRCm39)	I473N	probably damaging	Het
4933416I08Rik	TCC	TCCC	X: 52,692,862 (GRCm39)		noncoding transcript	Het
A530064D06Rik	T	C	17: 48,470,448 (GRCm39)	I178V	probably benign	Het
Acvr1b	A	G	15: 101,100,959 (GRCm39)	R374G	probably damaging	Het
Aldh1l2	G	A	10: 83,363,199 (GRCm39)	P55S	probably damaging	Het
Bglap3	T	C	3: 88,276,098 (GRCm39)	T85A	possibly damaging	Het
Cilp	TGGG	TGG	9: 65,187,412 (GRCm39)		probably null	Het
Crb1	CG	C	1: 139,164,824 (GRCm39)		probably null	Het
Csrnp3	A	G	2: 65,852,553 (GRCm39)	D315G	probably benign	Het
Dclk3	T	C	9: 111,317,643 (GRCm39)	Y760H	probably damaging	Het
Eef1akmt2	A	G	7: 132,438,935 (GRCm39)	*52R	probably null	Het
Epc2	A	G	2: 49,418,866 (GRCm39)	K225E	probably damaging	Het
Fcna	G	C	2: 25,520,693 (GRCm39)		probably benign	Het
Foxi2	C	T	7: 135,012,127 (GRCm39)	T5M	possibly damaging	Het
Frmd4b	T	A	6: 97,273,221 (GRCm39)	T670S	probably damaging	Het
Gm14137	G	T	2: 119,005,961 (GRCm39)	E173D	probably damaging	Het
Kif12	GGGGC	GGGGCCTCCACCCGGCGGGC	4: 63,089,660 (GRCm39)		probably benign	Het
Mlst8	A	G	17: 24,695,127 (GRCm39)	F252S	probably damaging	Het
Mmp1a	TG	TGG	9: 7,465,083 (GRCm38)		probably null	Het
Mogs	A	G	6: 83,094,296 (GRCm39)	K371R	probably benign	Het
Nsun2	T	C	13: 69,691,727 (GRCm39)		probably benign	Het
Otog	T	A	7: 45,954,932 (GRCm39)	C2702S	probably damaging	Het
Plekhg4	A	G	8: 106,107,020 (GRCm39)	E905G	probably damaging	Het
Rtn4rl1	T	C	11: 75,156,087 (GRCm39)	V173A	probably benign	Het
Sall3	T	C	18: 81,016,665 (GRCm39)	E421G	probably benign	Het
Setd6	G	A	8: 96,442,903 (GRCm39)		probably null	Het
Sh3tc1	T	C	5: 35,871,403 (GRCm39)		probably null	Het
Slc35f5	T	A	1: 125,490,250 (GRCm39)	Y71N	probably benign	Het
Snx1	A	G	9: 65,996,390 (GRCm39)		probably benign	Het
Speer4c1	A	C	5: 15,919,214 (GRCm39)		probably benign	Het
Sspo	T	C	6: 48,472,089 (GRCm39)	V792A	probably benign	Het
Sufu	C	A	19: 46,462,038 (GRCm39)	D350E	probably benign	Het
Trav18	C	A	14: 54,069,026 (GRCm39)	Q23K	probably damaging	Het
Ugt1a1	AT	A	1: 88,140,093 (GRCm39)		probably null	Het
Usp17le	T	A	7: 104,418,311 (GRCm39)	H277L	probably benign	Het
Wdsub1	A	G	2: 59,707,173 (GRCm39)	S20P	probably damaging	Het

Other mutations in Mfsd4b3-ps

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01135:Mfsd4b3-ps	APN	10	39,824,068 (GRCm39)	missense	probably benign	0.30
IGL02903:Mfsd4b3-ps	APN	10	39,823,639 (GRCm39)	missense	possibly damaging	0.76
IGL03013:Mfsd4b3-ps	APN	10	39,823,891 (GRCm39)	missense	probably benign	0.00
R0322:Mfsd4b3-ps	UTSW	10	39,823,526 (GRCm39)	missense	probably damaging	0.99
R1238:Mfsd4b3-ps	UTSW	10	39,823,222 (GRCm39)	missense	probably damaging	0.97
R1750:Mfsd4b3-ps	UTSW	10	39,823,929 (GRCm39)	missense	probably benign
R2345:Mfsd4b3-ps	UTSW	10	39,824,069 (GRCm39)	missense	probably benign
R4027:Mfsd4b3-ps	UTSW	10	39,823,343 (GRCm39)	missense	probably benign
R4906:Mfsd4b3-ps	UTSW	10	39,824,056 (GRCm39)	missense	probably damaging	1.00
R4965:Mfsd4b3-ps	UTSW	10	39,823,686 (GRCm39)	nonsense	probably null
R6456:Mfsd4b3-ps	UTSW	10	39,823,316 (GRCm39)	missense	probably benign	0.00
R8955:Mfsd4b3-ps	UTSW	10	39,824,072 (GRCm39)	missense	probably benign	0.00
R9115:Mfsd4b3-ps	UTSW	10	39,824,012 (GRCm39)	nonsense	probably null
R9256:Mfsd4b3-ps	UTSW	10	39,824,010 (GRCm39)	missense	probably damaging	0.99
R9461:Mfsd4b3-ps	UTSW	10	39,823,247 (GRCm39)	missense	probably benign
X0026:Mfsd4b3-ps	UTSW	10	39,823,429 (GRCm39)	missense	probably damaging	1.00

Posted On

2016-08-02