Incidental Mutation 'R6629:Fam136b-ps'
Institutional Source Beutler Lab
Gene Symbol Fam136b-ps
Ensembl Gene ENSMUSG00000055416
Gene Namefamily with sequence similarity 136, member B, pseudogene
MMRRC Submission
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.152) question?
Stock #R6629 (G1)
Quality Score225.009
Status Validated
Chromosomal Location31276491-31276907 bp(+) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) G to A at 31276816 bp
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000140481 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000044524] [ENSMUST00000068987] [ENSMUST00000185618] [ENSMUST00000186109] [ENSMUST00000186425] [ENSMUST00000186547]
Predicted Effect probably benign
Transcript: ENSMUST00000044524
SMART Domains Protein: ENSMUSP00000047186
Gene: ENSMUSG00000039168

Pfam:DAP 12 102 3.3e-34 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000068987
SMART Domains Protein: ENSMUSP00000125904
Gene: ENSMUSG00000055416

Pfam:DUF842 5 132 2.4e-48 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000185618
SMART Domains Protein: ENSMUSP00000140568
Gene: ENSMUSG00000039168

Pfam:DAP 3 62 4.5e-15 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000186109
Predicted Effect probably benign
Transcript: ENSMUST00000186425
SMART Domains Protein: ENSMUSP00000140007
Gene: ENSMUSG00000039168

Pfam:DAP 1 79 6.5e-20 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000186547
SMART Domains Protein: ENSMUSP00000140481
Gene: ENSMUSG00000039168

Pfam:DAP 1 79 6.5e-20 PFAM
Coding Region Coverage
  • 1x: 99.9%
  • 3x: 99.5%
  • 10x: 97.7%
  • 20x: 92.8%
Validation Efficiency 97% (38/39)
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700011I03Rik T C 18: 57,730,780 S219P possibly damaging Het
Atxn3 A T 12: 101,937,406 M180K probably benign Het
Bnip2 G T 9: 70,002,111 R236L probably null Het
Boc T C 16: 44,492,361 D582G probably benign Het
Cacul1 T C 19: 60,580,367 S118G probably benign Het
Cpa2 A T 6: 30,554,194 D271V probably damaging Het
Cubn G A 2: 13,430,872 T1091M probably damaging Het
Dlgap2 A G 8: 14,831,465 T846A probably benign Het
Eif5 G T 12: 111,543,608 A329S probably damaging Het
Gnrhr A G 5: 86,182,309 V284A probably benign Het
Grin3a A G 4: 49,844,991 S31P probably damaging Het
Hectd2 T C 19: 36,615,538 L701P probably damaging Het
Hook1 C T 4: 96,001,270 T241I probably benign Het
Kif5a A G 10: 127,248,254 V52A probably damaging Het
Lasp1 T A 11: 97,806,896 Y11* probably null Het
Meltf A G 16: 31,885,076 Y207C probably damaging Het
Nek1 A G 8: 61,054,333 probably null Het
Notch2 C A 3: 98,120,881 N969K possibly damaging Het
Olfr1221 T A 2: 89,112,162 M117L probably benign Het
Pcnx2 C T 8: 125,891,112 G135R probably benign Het
Pla2g4f A T 2: 120,308,242 L242Q probably damaging Het
Plcxd2 T G 16: 45,965,107 T312P probably damaging Het
Prpf4 G A 4: 62,417,860 V275I possibly damaging Het
Prpf8 G A 11: 75,495,426 probably null Het
Pxn T C 5: 115,554,062 L401P probably damaging Het
Rab44 A T 17: 29,135,780 probably benign Het
Rfx6 C A 10: 51,725,490 T669K probably benign Het
Rgs16 A G 1: 153,743,674 N142S probably damaging Het
Rhobtb1 A G 10: 69,270,316 E237G possibly damaging Het
Rsbn1 A C 3: 103,928,441 D265A probably damaging Het
Rufy4 A G 1: 74,132,367 probably null Het
Slc4a1 C A 11: 102,361,222 E19* probably null Het
Tctn1 A G 5: 122,242,668 S526P probably damaging Het
Tspear A T 10: 77,870,509 H371L probably benign Het
Vmn1r34 A T 6: 66,637,515 F80I probably benign Het
Wdr75 G A 1: 45,812,056 S264N probably damaging Het
Zfp652 A T 11: 95,763,790 N340Y probably damaging Het
Zp3 A G 5: 135,987,336 T306A probably benign Het
Other mutations in Fam136b-ps
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01289:Fam136b-ps APN 15 31276864 unclassified probably benign
R1080:Fam136b-ps UTSW 15 31276593 unclassified probably benign
R5033:Fam136b-ps UTSW 15 31276897 unclassified probably benign
R5070:Fam136b-ps UTSW 15 31276716 unclassified probably benign
R5110:Fam136b-ps UTSW 15 31276710 unclassified probably benign
Predicted Primers PCR Primer

Sequencing Primer
Posted On2018-06-22