Incidental Mutation 'R6922:Camta2'
| ID |
539686 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Camta2
|
| Ensembl Gene |
ENSMUSG00000040712 |
| Gene Name |
calmodulin binding transcription activator 2 |
| Synonyms |
Kiaa0909-hp |
| MMRRC Submission |
045041-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.496)
|
| Stock # |
R6922 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
70560289-70578931 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 70564964 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Serine
at position 852
(I852S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000104185
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000018431]
[ENSMUST00000036299]
[ENSMUST00000100933]
[ENSMUST00000108544]
[ENSMUST00000108545]
[ENSMUST00000119120]
[ENSMUST00000120261]
[ENSMUST00000129434]
[ENSMUST00000145823]
|
| AlphaFold |
Q80Y50 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000018431
|
| SMART Domains |
Protein: ENSMUSP00000018431
Gene: ENSMUSG00000018287
| Domain | Start | End | E-Value | Type |
|---|
|
R3H
|
31 |
109 |
3.85e-21 |
SMART |
|
low complexity region
|
130 |
152 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000036299
AA Change: I881S
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000043792
Gene: ENSMUSG00000040712
AA Change: I881S
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
155 |
1.07e-83 |
SMART |
|
low complexity region
|
232 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
273 |
291 |
N/A |
INTRINSIC |
|
low complexity region
|
294 |
305 |
N/A |
INTRINSIC |
|
low complexity region
|
314 |
329 |
N/A |
INTRINSIC |
|
low complexity region
|
370 |
380 |
N/A |
INTRINSIC |
|
low complexity region
|
417 |
435 |
N/A |
INTRINSIC |
|
low complexity region
|
461 |
485 |
N/A |
INTRINSIC |
|
low complexity region
|
501 |
514 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
541 |
621 |
6.2e-13 |
PFAM |
|
low complexity region
|
660 |
679 |
N/A |
INTRINSIC |
|
Blast:ANK
|
717 |
750 |
7e-12 |
BLAST |
|
SCOP:d1myo__
|
718 |
816 |
2e-15 |
SMART |
|
Blast:ANK
|
762 |
792 |
4e-11 |
BLAST |
|
low complexity region
|
829 |
839 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
853 |
N/A |
INTRINSIC |
|
low complexity region
|
861 |
882 |
N/A |
INTRINSIC |
|
IQ
|
1053 |
1075 |
2.59e2 |
SMART |
|
IQ
|
1076 |
1092 |
2.38e2 |
SMART |
|
IQ
|
1106 |
1128 |
5.42e0 |
SMART |
|
low complexity region
|
1140 |
1157 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1190 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100933
AA Change: I878S
PolyPhen 2
Score 0.038 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000098493
Gene: ENSMUSG00000040712
AA Change: I878S
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
36 |
152 |
8.08e-88 |
SMART |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
270 |
288 |
N/A |
INTRINSIC |
|
low complexity region
|
291 |
302 |
N/A |
INTRINSIC |
|
low complexity region
|
311 |
326 |
N/A |
INTRINSIC |
|
low complexity region
|
367 |
377 |
N/A |
INTRINSIC |
|
low complexity region
|
414 |
432 |
N/A |
INTRINSIC |
|
low complexity region
|
458 |
482 |
N/A |
INTRINSIC |
|
low complexity region
|
498 |
511 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
538 |
618 |
1.2e-8 |
PFAM |
|
low complexity region
|
657 |
676 |
N/A |
INTRINSIC |
|
Blast:ANK
|
714 |
747 |
8e-12 |
BLAST |
|
SCOP:d1myo__
|
715 |
813 |
2e-15 |
SMART |
|
Blast:ANK
|
759 |
789 |
4e-11 |
BLAST |
|
low complexity region
|
826 |
836 |
N/A |
INTRINSIC |
|
low complexity region
|
841 |
850 |
N/A |
INTRINSIC |
|
low complexity region
|
858 |
879 |
N/A |
INTRINSIC |
|
IQ
|
1050 |
1072 |
2.59e2 |
SMART |
|
IQ
|
1073 |
1095 |
1.18e1 |
SMART |
|
IQ
|
1096 |
1118 |
5.42e0 |
SMART |
|
low complexity region
|
1130 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1180 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108544
AA Change: I876S
PolyPhen 2
Score 0.011 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000104184
Gene: ENSMUSG00000040712
AA Change: I876S
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
150 |
8.08e-88 |
SMART |
|
low complexity region
|
227 |
238 |
N/A |
INTRINSIC |
|
low complexity region
|
268 |
286 |
N/A |
INTRINSIC |
|
low complexity region
|
289 |
300 |
N/A |
INTRINSIC |
|
low complexity region
|
309 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
365 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
430 |
N/A |
INTRINSIC |
|
low complexity region
|
456 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
496 |
509 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
536 |
616 |
1.2e-8 |
PFAM |
|
low complexity region
|
655 |
674 |
N/A |
INTRINSIC |
|
Blast:ANK
|
712 |
745 |
7e-12 |
BLAST |
|
SCOP:d1myo__
|
713 |
811 |
2e-15 |
SMART |
|
Blast:ANK
|
757 |
787 |
4e-11 |
BLAST |
|
low complexity region
|
824 |
834 |
N/A |
INTRINSIC |
|
low complexity region
|
839 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
856 |
877 |
N/A |
INTRINSIC |
|
IQ
|
1048 |
1070 |
2.59e2 |
SMART |
|
IQ
|
1071 |
1087 |
2.38e2 |
SMART |
|
IQ
|
1101 |
1123 |
5.42e0 |
SMART |
|
low complexity region
|
1135 |
1152 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1185 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108545
AA Change: I852S
PolyPhen 2
Score 0.038 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000104185
Gene: ENSMUSG00000040712
AA Change: I852S
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
126 |
3.23e-55 |
SMART |
|
low complexity region
|
203 |
214 |
N/A |
INTRINSIC |
|
low complexity region
|
244 |
262 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
285 |
300 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
351 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
406 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
456 |
N/A |
INTRINSIC |
|
low complexity region
|
472 |
485 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
512 |
592 |
1.1e-8 |
PFAM |
|
low complexity region
|
631 |
650 |
N/A |
INTRINSIC |
|
Blast:ANK
|
688 |
721 |
7e-12 |
BLAST |
|
SCOP:d1myo__
|
689 |
787 |
2e-15 |
SMART |
|
Blast:ANK
|
733 |
763 |
5e-13 |
BLAST |
|
low complexity region
|
800 |
810 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
824 |
N/A |
INTRINSIC |
|
low complexity region
|
832 |
853 |
N/A |
INTRINSIC |
|
IQ
|
1024 |
1046 |
2.59e2 |
SMART |
|
IQ
|
1047 |
1069 |
1.18e1 |
SMART |
|
IQ
|
1070 |
1092 |
5.42e0 |
SMART |
|
low complexity region
|
1104 |
1121 |
N/A |
INTRINSIC |
|
low complexity region
|
1144 |
1154 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000119120
AA Change: I876S
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000113847
Gene: ENSMUSG00000040712
AA Change: I876S
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
150 |
8.08e-88 |
SMART |
|
low complexity region
|
227 |
238 |
N/A |
INTRINSIC |
|
low complexity region
|
268 |
286 |
N/A |
INTRINSIC |
|
low complexity region
|
289 |
300 |
N/A |
INTRINSIC |
|
low complexity region
|
309 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
365 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
430 |
N/A |
INTRINSIC |
|
low complexity region
|
456 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
496 |
509 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
536 |
616 |
1.1e-8 |
PFAM |
|
low complexity region
|
655 |
674 |
N/A |
INTRINSIC |
|
Blast:ANK
|
712 |
745 |
7e-12 |
BLAST |
|
SCOP:d1myo__
|
713 |
811 |
2e-15 |
SMART |
|
Blast:ANK
|
757 |
787 |
8e-13 |
BLAST |
|
low complexity region
|
824 |
834 |
N/A |
INTRINSIC |
|
low complexity region
|
839 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
856 |
877 |
N/A |
INTRINSIC |
|
IQ
|
1048 |
1070 |
2.59e2 |
SMART |
|
IQ
|
1071 |
1093 |
1.18e1 |
SMART |
|
IQ
|
1094 |
1116 |
5.42e0 |
SMART |
|
low complexity region
|
1128 |
1145 |
N/A |
INTRINSIC |
|
low complexity region
|
1168 |
1178 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000120261
AA Change: I852S
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000113667
Gene: ENSMUSG00000040712
AA Change: I852S
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
126 |
3.23e-55 |
SMART |
|
low complexity region
|
203 |
214 |
N/A |
INTRINSIC |
|
low complexity region
|
244 |
262 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
285 |
300 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
351 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
406 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
456 |
N/A |
INTRINSIC |
|
low complexity region
|
472 |
485 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
512 |
592 |
1e-8 |
PFAM |
|
low complexity region
|
631 |
650 |
N/A |
INTRINSIC |
|
Blast:ANK
|
688 |
721 |
7e-12 |
BLAST |
|
SCOP:d1myo__
|
689 |
787 |
2e-15 |
SMART |
|
Blast:ANK
|
733 |
763 |
7e-13 |
BLAST |
|
low complexity region
|
800 |
810 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
824 |
N/A |
INTRINSIC |
|
low complexity region
|
832 |
853 |
N/A |
INTRINSIC |
|
IQ
|
1024 |
1046 |
2.59e2 |
SMART |
|
IQ
|
1047 |
1063 |
2.38e2 |
SMART |
|
IQ
|
1077 |
1099 |
5.42e0 |
SMART |
|
low complexity region
|
1111 |
1128 |
N/A |
INTRINSIC |
|
low complexity region
|
1151 |
1161 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129434
|
| SMART Domains |
Protein: ENSMUSP00000115098
Gene: ENSMUSG00000018287
| Domain | Start | End | E-Value | Type |
|---|
|
R3H
|
22 |
99 |
3.06e-15 |
SMART |
|
low complexity region
|
120 |
142 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145823
|
| SMART Domains |
Protein: ENSMUSP00000123602
Gene: ENSMUSG00000040712
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
137 |
2.55e-44 |
SMART |
|
low complexity region
|
146 |
165 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.3%
- 20x: 97.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the calmodulin-binding transcription activator protein family. Members of this family share a common domain structure that consists of a transcription activation domain, a DNA-binding domain, and a calmodulin-binding domain. The encoded protein may be a transcriptional coactivator of genes involved in cardiac growth. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2010]
PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and free of obvious cardiac defects, but show reduced pathophysiologic cardiac hypertrophy in response to diverse stress stimuli. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 44 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ago2 |
T |
C |
15: 72,985,601 (GRCm39) |
I665V |
probably benign |
Het |
| Aoc1l3 |
T |
G |
6: 48,964,508 (GRCm39) |
F172C |
probably damaging |
Het |
| Arhgap32 |
A |
T |
9: 32,063,983 (GRCm39) |
M74L |
possibly damaging |
Het |
| Asb4 |
T |
C |
6: 5,398,304 (GRCm39) |
C90R |
possibly damaging |
Het |
| B3galt4 |
T |
A |
17: 34,169,821 (GRCm39) |
D139V |
probably damaging |
Het |
| Cd200l1 |
A |
T |
16: 45,264,294 (GRCm39) |
M88K |
probably benign |
Het |
| Cox4i2 |
G |
T |
2: 152,599,015 (GRCm39) |
E57D |
probably benign |
Het |
| Dip2b |
T |
C |
15: 100,091,724 (GRCm39) |
I1055T |
probably benign |
Het |
| Eif1ad18 |
T |
A |
12: 88,050,602 (GRCm39) |
W46R |
probably benign |
Het |
| Eif4g3 |
C |
T |
4: 137,824,646 (GRCm39) |
P284S |
probably damaging |
Het |
| Ephb1 |
C |
A |
9: 101,806,463 (GRCm39) |
|
probably null |
Het |
| Fbxw7 |
A |
T |
3: 84,879,723 (GRCm39) |
|
probably null |
Het |
| Frem1 |
C |
A |
4: 82,840,506 (GRCm39) |
D1789Y |
probably damaging |
Het |
| Gm29106 |
A |
T |
1: 118,127,524 (GRCm39) |
R405S |
probably damaging |
Het |
| Greb1l |
G |
A |
18: 10,547,482 (GRCm39) |
V1567M |
possibly damaging |
Het |
| Hapstr1 |
A |
G |
16: 8,648,553 (GRCm39) |
|
probably null |
Het |
| Heatr1 |
C |
A |
13: 12,449,956 (GRCm39) |
D1983E |
probably benign |
Het |
| Lhfpl2 |
G |
T |
13: 94,311,029 (GRCm39) |
A100S |
probably damaging |
Het |
| Lrp5 |
A |
T |
19: 3,655,301 (GRCm39) |
V1073D |
probably damaging |
Het |
| Naip6 |
G |
A |
13: 100,438,706 (GRCm39) |
L364F |
possibly damaging |
Het |
| Nek9 |
A |
G |
12: 85,350,311 (GRCm39) |
L921P |
probably damaging |
Het |
| Nim1k |
C |
T |
13: 120,189,263 (GRCm39) |
E49K |
probably damaging |
Het |
| Nsun5 |
A |
C |
5: 135,399,046 (GRCm39) |
N32T |
probably damaging |
Het |
| Nuggc |
T |
C |
14: 65,855,092 (GRCm39) |
S325P |
probably damaging |
Het |
| Or2d36 |
A |
G |
7: 106,747,290 (GRCm39) |
I256V |
probably damaging |
Het |
| Or5w12 |
T |
A |
2: 87,501,797 (GRCm39) |
K305* |
probably null |
Het |
| Pcdhga7 |
A |
G |
18: 37,848,710 (GRCm39) |
D239G |
probably damaging |
Het |
| Pld2 |
A |
G |
11: 70,444,273 (GRCm39) |
D523G |
probably benign |
Het |
| Prokr1 |
C |
A |
6: 87,565,455 (GRCm39) |
W130L |
probably damaging |
Het |
| Prpf8 |
A |
G |
11: 75,381,562 (GRCm39) |
N266S |
probably damaging |
Het |
| Rdh10 |
T |
C |
1: 16,176,255 (GRCm39) |
V5A |
probably benign |
Het |
| Rp1l1 |
T |
C |
14: 64,267,834 (GRCm39) |
L1140P |
possibly damaging |
Het |
| Sacs |
A |
G |
14: 61,448,874 (GRCm39) |
D3640G |
probably damaging |
Het |
| Smarca2 |
A |
G |
19: 26,668,749 (GRCm39) |
E916G |
probably damaging |
Het |
| Steap3 |
A |
T |
1: 120,171,624 (GRCm39) |
H160Q |
probably damaging |
Het |
| Tlk2 |
T |
C |
11: 105,147,779 (GRCm39) |
|
probably null |
Het |
| Tmprss4 |
A |
G |
9: 45,097,220 (GRCm39) |
V15A |
probably benign |
Het |
| Togaram2 |
T |
C |
17: 72,014,129 (GRCm39) |
L559P |
probably damaging |
Het |
| Topbp1 |
T |
A |
9: 103,213,045 (GRCm39) |
L990H |
probably damaging |
Het |
| Ttll7 |
A |
G |
3: 146,615,369 (GRCm39) |
T278A |
possibly damaging |
Het |
| Ttn |
G |
A |
2: 76,604,780 (GRCm39) |
L18385F |
probably damaging |
Het |
| Upf3a |
G |
T |
8: 13,841,911 (GRCm39) |
A149S |
probably damaging |
Het |
| Vmn2r111 |
T |
C |
17: 22,778,032 (GRCm39) |
N549S |
possibly damaging |
Het |
| Zfp316 |
A |
T |
5: 143,239,280 (GRCm39) |
F913Y |
probably damaging |
Het |
|
| Other mutations in Camta2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01022:Camta2
|
APN |
11 |
70,562,308 (GRCm39) |
nonsense |
probably null |
|
|
IGL01472:Camta2
|
APN |
11 |
70,574,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02548:Camta2
|
APN |
11 |
70,561,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Camta2
|
APN |
11 |
70,566,484 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02983:Camta2
|
APN |
11 |
70,562,848 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03035:Camta2
|
APN |
11 |
70,562,335 (GRCm39) |
nonsense |
probably null |
|
|
weeping
|
UTSW |
11 |
70,574,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Willow
|
UTSW |
11 |
70,569,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0027:Camta2
|
UTSW |
11 |
70,574,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0360:Camta2
|
UTSW |
11 |
70,574,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0364:Camta2
|
UTSW |
11 |
70,574,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0541:Camta2
|
UTSW |
11 |
70,572,447 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0600:Camta2
|
UTSW |
11 |
70,564,785 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0630:Camta2
|
UTSW |
11 |
70,569,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1301:Camta2
|
UTSW |
11 |
70,567,230 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1346:Camta2
|
UTSW |
11 |
70,567,293 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1826:Camta2
|
UTSW |
11 |
70,574,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1881:Camta2
|
UTSW |
11 |
70,562,842 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1980:Camta2
|
UTSW |
11 |
70,573,308 (GRCm39) |
missense |
probably benign |
0.43 |
|
R2144:Camta2
|
UTSW |
11 |
70,562,401 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2145:Camta2
|
UTSW |
11 |
70,562,401 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2763:Camta2
|
UTSW |
11 |
70,573,356 (GRCm39) |
nonsense |
probably null |
|
|
R2881:Camta2
|
UTSW |
11 |
70,570,490 (GRCm39) |
splice site |
probably null |
|
|
R2917:Camta2
|
UTSW |
11 |
70,571,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4115:Camta2
|
UTSW |
11 |
70,567,300 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4321:Camta2
|
UTSW |
11 |
70,569,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4470:Camta2
|
UTSW |
11 |
70,571,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4499:Camta2
|
UTSW |
11 |
70,565,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4509:Camta2
|
UTSW |
11 |
70,571,844 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6154:Camta2
|
UTSW |
11 |
70,569,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6166:Camta2
|
UTSW |
11 |
70,565,087 (GRCm39) |
splice site |
probably null |
|
|
R6287:Camta2
|
UTSW |
11 |
70,572,295 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6382:Camta2
|
UTSW |
11 |
70,562,867 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6864:Camta2
|
UTSW |
11 |
70,562,792 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7438:Camta2
|
UTSW |
11 |
70,574,714 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7611:Camta2
|
UTSW |
11 |
70,572,372 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7883:Camta2
|
UTSW |
11 |
70,566,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8094:Camta2
|
UTSW |
11 |
70,576,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8232:Camta2
|
UTSW |
11 |
70,573,841 (GRCm39) |
missense |
unknown |
|
|
R8271:Camta2
|
UTSW |
11 |
70,561,886 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8973:Camta2
|
UTSW |
11 |
70,561,184 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9072:Camta2
|
UTSW |
11 |
70,567,234 (GRCm39) |
missense |
probably benign |
0.21 |
|
T0722:Camta2
|
UTSW |
11 |
70,574,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Camta2
|
UTSW |
11 |
70,572,504 (GRCm39) |
missense |
probably benign |
0.08 |
|
Z1177:Camta2
|
UTSW |
11 |
70,566,047 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAATGTGTTTCACCCAGCCTC -3'
(R):5'- ACTGAGGAGGCTGCAGCTC -3'
Sequencing Primer
(F):5'- GCAGTACCGGGATCACATC -3'
(R):5'- GCTCCTGCTGCTATCCCTAC -3'
|
| Posted On |
2018-11-06 |
Incidental Mutation