Mutagenetix > Incidental Mutation

Incidental Mutation 'R1861:Fcgbpl1'

203914

Institutional Source

Beutler Lab

Gene Symbol

Fcgbpl1

Ensembl Gene

ENSMUSG00000078776

Gene Name

Fc fragment of IgG binding protein like 1

Synonyms

9530053A07Rik

MMRRC Submission

039884-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.103) question?

Stock #

R1861 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

27828891-27864236 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 27854157 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Cysteine at position 1707 (Y1707C)

Ref Sequence

ENSEMBL: ENSMUSP00000114986 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000059886] [ENSMUST00000150948]

AlphaFold

E9PVG8

Predicted Effect

probably damaging
Transcript: ENSMUST00000059886
AA Change: Y1707C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000056479
Gene: ENSMUSG00000078776
AA Change: Y1707C

Domain	Start	End	E-Value	Type
low complexity region	8	24	N/A	INTRINSIC
FOLN	27	49	1.23e-4	SMART
VWD	46	211	1.5e-40	SMART
C8	251	326	4.31e-33	SMART
Pfam:TIL	329	383	2e-13	PFAM
VWC	385	448	1.02e0	SMART
VWD	439	603	4.32e-32	SMART
C8	640	715	4.54e-9	SMART
Pfam:TIL	718	771	1.6e-12	PFAM
VWC	773	826	1.1e0	SMART
FOLN	805	827	6.87e1	SMART
VWD	825	988	7.92e-40	SMART
C8	1033	1108	5.1e-35	SMART
Pfam:TIL	1111	1164	7.6e-11	PFAM
VWC	1166	1224	1.1e-2	SMART
FOLN	1197	1219	9.55e-1	SMART
FOLN	1223	1245	5.38e1	SMART
VWD	1241	1410	9.04e-35	SMART
C8	1450	1526	9.54e-26	SMART
low complexity region	1540	1550	N/A	INTRINSIC
EGF_like	1557	1580	5.34e1	SMART
VWC	1588	1681	3.21e-3	SMART
VWD	1639	1806	7.3e-30	SMART
C8	1838	1913	2.44e-32	SMART
EGF_like	1941	1964	4.46e1	SMART
VWC	1971	2062	2.85e-1	SMART
VWD	2022	2178	1.32e-27	SMART
low complexity region	2199	2212	N/A	INTRINSIC
C8	2219	2294	1.43e-29	SMART
Pfam:TIL	2297	2350	1.1e-11	PFAM
FOLN	2383	2405	5.68e1	SMART
VWD	2402	2564	4.58e-4	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000150948
AA Change: Y1707C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000114986
Gene: ENSMUSG00000078776
AA Change: Y1707C

Domain	Start	End	E-Value	Type
low complexity region	8	24	N/A	INTRINSIC
FOLN	27	49	1.23e-4	SMART
VWD	46	211	1.5e-40	SMART
C8	251	326	4.31e-33	SMART
Pfam:TIL	329	383	2e-13	PFAM
VWC	385	448	1.02e0	SMART
VWD	439	603	4.32e-32	SMART
C8	640	715	4.54e-9	SMART
Pfam:TIL	718	771	1.6e-12	PFAM
VWC	773	826	1.1e0	SMART
FOLN	805	827	6.87e1	SMART
VWD	825	988	7.92e-40	SMART
C8	1033	1108	5.1e-35	SMART
Pfam:TIL	1111	1164	7.6e-11	PFAM
VWC	1166	1224	1.1e-2	SMART
FOLN	1197	1219	9.55e-1	SMART
FOLN	1223	1245	5.38e1	SMART
VWD	1241	1410	9.04e-35	SMART
C8	1450	1526	9.54e-26	SMART
low complexity region	1540	1550	N/A	INTRINSIC
EGF_like	1557	1580	5.34e1	SMART
VWC	1588	1681	3.21e-3	SMART
VWD	1639	1806	7.3e-30	SMART
C8	1838	1913	2.44e-32	SMART
EGF_like	1941	1964	4.46e1	SMART
VWC	1971	2062	2.85e-1	SMART
VWD	2022	2178	1.32e-27	SMART
low complexity region	2199	2212	N/A	INTRINSIC
C8	2219	2294	1.43e-29	SMART
Pfam:TIL	2297	2350	1.1e-11	PFAM
FOLN	2383	2405	5.68e1	SMART
VWD	2402	2564	4.58e-4	SMART

Meta Mutation Damage Score

0.6467

Coding Region Coverage

1x: 97.4%
3x: 96.9%
10x: 95.2%
20x: 92.0%

Validation Efficiency

97% (117/121)

Allele List at MGI

Other mutations in this stock

Total: 113 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930579C12Rik	C	A	9: 89,034,884 (GRCm39)		noncoding transcript	Het
Abra	C	A	15: 41,732,430 (GRCm39)	R212L	probably damaging	Het
Actr1a	T	C	19: 46,372,714 (GRCm39)	E87G	probably damaging	Het
Adam26a	A	G	8: 44,022,578 (GRCm39)	V304A	possibly damaging	Het
Alg2	T	A	4: 47,471,670 (GRCm39)	K379N	probably benign	Het
Alk	G	T	17: 72,181,933 (GRCm39)		probably benign	Het
Aopep	A	G	13: 63,163,597 (GRCm39)	Y206C	probably damaging	Het
Arhgef17	A	G	7: 100,531,475 (GRCm39)	Y331H	probably damaging	Het
Art3	A	G	5: 92,560,094 (GRCm39)		probably benign	Het
Asap1	G	A	15: 64,007,647 (GRCm39)		probably benign	Het
Atad2	A	T	15: 57,960,114 (GRCm39)		probably null	Het
Atp8b5	G	A	4: 43,372,906 (GRCm39)	R1150H	probably damaging	Het
Bltp2	C	T	11: 78,178,755 (GRCm39)		probably benign	Het
Brdt	T	C	5: 107,507,324 (GRCm39)	S575P	probably benign	Het
Capn3	T	A	2: 120,316,963 (GRCm39)		probably benign	Het
Casd1	T	A	6: 4,640,951 (GRCm39)	Y691N	probably damaging	Het
Ccdc127	T	G	13: 74,505,098 (GRCm39)	H215Q	possibly damaging	Het
Cenpe	T	C	3: 134,974,740 (GRCm39)	L2300P	probably damaging	Het
Clasp1	T	C	1: 118,498,661 (GRCm39)	F898L	possibly damaging	Het
Clcn1	C	A	6: 42,290,925 (GRCm39)	P933Q	possibly damaging	Het
Cntn3	T	A	6: 102,222,032 (GRCm39)	N489I	probably benign	Het
Col16a1	T	C	4: 129,955,517 (GRCm39)		probably benign	Het
Col24a1	G	A	3: 145,243,022 (GRCm39)		probably null	Het
Col8a2	C	T	4: 126,205,417 (GRCm39)		probably benign	Het
Cpd	T	C	11: 76,675,208 (GRCm39)		probably benign	Het
Csmd3	A	T	15: 47,522,588 (GRCm39)	C2694S	probably damaging	Het
Cyp2c40	T	C	19: 39,775,319 (GRCm39)	Y311C	probably benign	Het
Dennd5b	T	A	6: 148,969,760 (GRCm39)	N231I	probably damaging	Het
Dgkh	T	A	14: 78,816,232 (GRCm39)	H936L	probably benign	Het
Dmtf1	T	C	5: 9,170,347 (GRCm39)		probably null	Het
Dnai2	T	C	11: 114,643,777 (GRCm39)	V481A	possibly damaging	Het
Dnai3	T	C	3: 145,788,801 (GRCm39)	Y260C	probably damaging	Het
Dpyd	T	G	3: 118,710,780 (GRCm39)	V396G	probably damaging	Het
Elmo3	A	G	8: 106,035,213 (GRCm39)	D448G	probably damaging	Het
Emsy	A	T	7: 98,290,822 (GRCm39)	V100E	probably damaging	Het
Erbb2	T	C	11: 98,303,563 (GRCm39)		probably null	Het
Faah	T	C	4: 115,865,432 (GRCm39)	K85R	probably benign	Het
Fam149a	A	T	8: 45,792,399 (GRCm39)	Y686*	probably null	Het
Fat4	T	C	3: 39,064,633 (GRCm39)	V4863A	probably benign	Het
Fbxl8	A	G	8: 105,995,561 (GRCm39)	T358A	probably damaging	Het
Fgfr3	A	G	5: 33,887,090 (GRCm39)	T165A	probably damaging	Het
Fnbp1l	A	T	3: 122,354,581 (GRCm39)	H180Q	probably damaging	Het
Gm8180	T	A	14: 44,021,196 (GRCm39)	H4L	probably benign	Het
Gon4l	T	C	3: 88,802,794 (GRCm39)	V1135A	probably damaging	Het
Gstcd	G	T	3: 132,688,868 (GRCm39)	N627K	probably damaging	Het
Gtf2a1l	G	A	17: 89,022,382 (GRCm39)	V458I	probably damaging	Het
Gtf3c3	T	C	1: 54,477,997 (GRCm39)	E26G	possibly damaging	Het
Hrct1	A	T	4: 43,727,404 (GRCm39)	T15S	probably benign	Het
Ift122	C	A	6: 115,868,889 (GRCm39)	R459S	probably damaging	Het
Irf1	T	A	11: 53,665,183 (GRCm39)	C187S	possibly damaging	Het
Kcnh7	A	G	2: 62,607,736 (GRCm39)	V615A	probably damaging	Het
Kif1c	T	C	11: 70,594,168 (GRCm39)	S61P	probably damaging	Het
Mamdc2	T	C	19: 23,336,517 (GRCm39)	T331A	probably damaging	Het
Mark2	T	C	19: 7,268,128 (GRCm39)	D25G	possibly damaging	Het
Me2	T	C	18: 73,918,785 (GRCm39)	D432G	probably benign	Het
Mfap3	T	C	11: 57,419,032 (GRCm39)	V64A	probably benign	Het
Nadk2	T	A	15: 9,108,399 (GRCm39)	M416K	probably benign	Het
Ndufs1	C	T	1: 63,186,576 (GRCm39)	G631D	probably benign	Het
Nomo1	G	A	7: 45,727,525 (GRCm39)	V1055I	probably benign	Het
Nuggc	T	A	14: 65,879,450 (GRCm39)		probably benign	Het
Nwd2	T	C	5: 63,962,197 (GRCm39)	S594P	probably damaging	Het
Or13c3	T	A	4: 52,856,373 (GRCm39)	I47L	probably benign	Het
Or4a27	T	G	2: 88,559,674 (GRCm39)	I90L	probably damaging	Het
Or4b1b	C	A	2: 90,112,502 (GRCm39)	C139F	probably damaging	Het
Or5b113	T	A	19: 13,342,705 (GRCm39)	S238T	possibly damaging	Het
Or6p1	T	C	1: 174,258,657 (GRCm39)	I221T	probably damaging	Het
Or8c10	C	T	9: 38,278,902 (GRCm39)	S10L	probably benign	Het
Pakap	A	G	4: 57,709,468 (GRCm39)	I138V	probably damaging	Het
Pcyt2	G	A	11: 120,501,968 (GRCm39)	P332S	probably benign	Het
Phaf1	A	G	8: 105,966,703 (GRCm39)	E150G	probably null	Het
Phf14	A	T	6: 11,987,610 (GRCm39)	M630L	probably benign	Het
Piezo1	T	C	8: 123,222,489 (GRCm39)	N919S	possibly damaging	Het
Pif1	A	T	9: 65,496,735 (GRCm39)	I283F	probably damaging	Het
Pknox2	G	A	9: 36,834,957 (GRCm39)	H171Y	probably damaging	Het
Pramel17	A	T	4: 101,694,135 (GRCm39)	D249E	probably benign	Het
Prkg2	T	A	5: 99,095,275 (GRCm39)	D632V	probably damaging	Het
Prr29	G	A	11: 106,266,264 (GRCm39)	A6T	probably damaging	Het
Rims1	T	A	1: 22,635,639 (GRCm39)	Y114F	probably damaging	Het
Ryr1	A	T	7: 28,708,977 (GRCm39)	D4796E	unknown	Het
Scnn1b	G	A	7: 121,513,484 (GRCm39)	C399Y	probably damaging	Het
Scp2	T	C	4: 107,948,518 (GRCm39)	Y153C	probably damaging	Het
Sema3d	A	G	5: 12,547,570 (GRCm39)	K164R	probably benign	Het
Siglecf	A	G	7: 43,001,648 (GRCm39)	T153A	probably benign	Het
Siglecf	A	G	7: 43,004,967 (GRCm39)	N399S	probably benign	Het
Skint2	T	C	4: 112,504,315 (GRCm39)		probably benign	Het
Slc22a8	G	A	19: 8,583,503 (GRCm39)	R236H	probably damaging	Het
Slc25a40	T	A	5: 8,492,431 (GRCm39)		probably null	Het
Slc26a5	T	C	5: 22,021,956 (GRCm39)	D490G	possibly damaging	Het
Slc26a7	G	T	4: 14,522,873 (GRCm39)	D482E	probably benign	Het
Smarca2	A	T	19: 26,601,284 (GRCm39)	M77L	probably benign	Het
Sos2	A	G	12: 69,664,137 (GRCm39)	L449P	probably damaging	Het
Spaca1	A	G	4: 34,044,206 (GRCm39)	V96A	probably damaging	Het
Spata31d1b	T	A	13: 59,865,150 (GRCm39)	I766N	possibly damaging	Het
Specc1l	T	C	10: 75,145,693 (GRCm39)	Y1113H	probably damaging	Het
Speg	A	G	1: 75,365,649 (GRCm39)	R677G	probably damaging	Het
Taf5l	A	T	8: 124,724,729 (GRCm39)	D363E	probably damaging	Het
Tex56	A	T	13: 35,116,490 (GRCm39)	I80F	possibly damaging	Het
Tmem208	A	G	8: 106,061,438 (GRCm39)	K155E	possibly damaging	Het
Tppp2	A	C	14: 52,158,062 (GRCm39)	N169T	probably benign	Het
Trrap	T	A	5: 144,752,727 (GRCm39)		probably null	Het
Ttll6	T	A	11: 96,029,700 (GRCm39)	Y204*	probably null	Het
Ttn	A	T	2: 76,602,992 (GRCm39)	I18410K	probably benign	Het
V1rd19	T	A	7: 23,703,149 (GRCm39)	V205D	probably damaging	Het
Vdac3	A	T	8: 23,070,515 (GRCm39)	I132K	possibly damaging	Het
Vmn2r95	T	G	17: 18,672,530 (GRCm39)	C756G	probably damaging	Het
Zc3h15	A	G	2: 83,494,334 (GRCm39)	T421A	unknown	Het
Zc3hc1	T	C	6: 30,374,837 (GRCm39)	T235A	probably benign	Het
Zcchc14	A	G	8: 122,335,990 (GRCm39)		probably benign	Het
Zfp318	T	A	17: 46,722,366 (GRCm39)	N1456K	possibly damaging	Het
Zfp606	A	G	7: 12,214,858 (GRCm39)		probably benign	Het
Zfp811	T	A	17: 33,016,399 (GRCm39)	H546L	probably damaging	Het
Zfp94	A	T	7: 24,008,541 (GRCm39)	Y33N	probably damaging	Het
Zfyve9	G	T	4: 108,539,492 (GRCm39)		probably benign	Het

Other mutations in Fcgbpl1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00435:Fcgbpl1	APN	7	27,863,953 (GRCm39)	missense	probably damaging	1.00
IGL00757:Fcgbpl1	APN	7	27,853,870 (GRCm39)	missense	probably damaging	1.00
IGL01015:Fcgbpl1	APN	7	27,854,743 (GRCm39)	missense	probably damaging	1.00
IGL01079:Fcgbpl1	APN	7	27,839,203 (GRCm39)	missense	probably damaging	0.99
IGL01343:Fcgbpl1	APN	7	27,850,127 (GRCm39)	missense	probably benign	0.19
IGL01420:Fcgbpl1	APN	7	27,839,558 (GRCm39)	missense	probably benign	0.28
IGL01604:Fcgbpl1	APN	7	27,854,749 (GRCm39)	missense	probably benign	0.11
IGL01666:Fcgbpl1	APN	7	27,852,717 (GRCm39)	missense	probably damaging	1.00
IGL02002:Fcgbpl1	APN	7	27,852,221 (GRCm39)	missense	probably damaging	1.00
IGL02036:Fcgbpl1	APN	7	27,836,950 (GRCm39)	missense	possibly damaging	0.82
IGL02126:Fcgbpl1	APN	7	27,839,281 (GRCm39)	missense	probably damaging	1.00
IGL02150:Fcgbpl1	APN	7	27,846,204 (GRCm39)	nonsense	probably null
IGL02219:Fcgbpl1	APN	7	27,854,060 (GRCm39)	missense	probably damaging	1.00
IGL02563:Fcgbpl1	APN	7	27,857,317 (GRCm39)	missense	probably benign
IGL02804:Fcgbpl1	APN	7	27,852,795 (GRCm39)	missense	probably benign	0.00
IGL02830:Fcgbpl1	APN	7	27,862,348 (GRCm39)	missense	probably damaging	1.00
IGL02943:Fcgbpl1	APN	7	27,846,613 (GRCm39)	missense	probably damaging	1.00
IGL02977:Fcgbpl1	APN	7	27,863,797 (GRCm39)	missense	possibly damaging	0.83
IGL03231:Fcgbpl1	APN	7	27,853,147 (GRCm39)	missense	possibly damaging	0.95
IGL03304:Fcgbpl1	APN	7	27,841,667 (GRCm39)	missense	probably damaging	0.99
herz	UTSW	7	27,853,264 (GRCm39)	missense	possibly damaging	0.72
pulse	UTSW	7	27,853,174 (GRCm39)	missense	probably damaging	1.00
Sinusoidal	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
PIT4378001:Fcgbpl1	UTSW	7	27,853,889 (GRCm39)	missense	possibly damaging	0.61
R0023:Fcgbpl1	UTSW	7	27,852,837 (GRCm39)	missense	probably benign	0.00
R0131:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0131:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0132:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0158:Fcgbpl1	UTSW	7	27,854,917 (GRCm39)	missense	probably damaging	1.00
R0230:Fcgbpl1	UTSW	7	27,856,250 (GRCm39)	missense	probably damaging	1.00
R0310:Fcgbpl1	UTSW	7	27,841,699 (GRCm39)	missense	probably benign	0.04
R0448:Fcgbpl1	UTSW	7	27,839,660 (GRCm39)	missense	probably benign	0.03
R0462:Fcgbpl1	UTSW	7	27,836,765 (GRCm39)	missense	probably damaging	1.00
R0481:Fcgbpl1	UTSW	7	27,853,174 (GRCm39)	missense	probably damaging	1.00
R0497:Fcgbpl1	UTSW	7	27,846,890 (GRCm39)	missense	probably damaging	1.00
R0556:Fcgbpl1	UTSW	7	27,858,803 (GRCm39)	missense	probably benign
R0562:Fcgbpl1	UTSW	7	27,862,115 (GRCm39)	missense	probably benign	0.30
R0586:Fcgbpl1	UTSW	7	27,836,516 (GRCm39)	missense	probably damaging	0.99
R0924:Fcgbpl1	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
R0930:Fcgbpl1	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
R1103:Fcgbpl1	UTSW	7	27,853,945 (GRCm39)	missense	probably damaging	1.00
R1213:Fcgbpl1	UTSW	7	27,857,098 (GRCm39)	missense	probably damaging	1.00
R1292:Fcgbpl1	UTSW	7	27,842,219 (GRCm39)	splice site	probably benign
R1368:Fcgbpl1	UTSW	7	27,858,903 (GRCm39)	missense	possibly damaging	0.89
R1451:Fcgbpl1	UTSW	7	27,836,582 (GRCm39)	missense	probably damaging	1.00
R1477:Fcgbpl1	UTSW	7	27,856,518 (GRCm39)	missense	probably benign	0.01
R1538:Fcgbpl1	UTSW	7	27,854,917 (GRCm39)	missense	probably damaging	1.00
R1655:Fcgbpl1	UTSW	7	27,846,535 (GRCm39)	missense	probably damaging	0.98
R1697:Fcgbpl1	UTSW	7	27,853,772 (GRCm39)	missense	probably damaging	1.00
R1741:Fcgbpl1	UTSW	7	27,857,279 (GRCm39)	missense	probably damaging	0.98
R1796:Fcgbpl1	UTSW	7	27,854,797 (GRCm39)	missense	probably damaging	1.00
R1853:Fcgbpl1	UTSW	7	27,854,971 (GRCm39)	nonsense	probably null
R1909:Fcgbpl1	UTSW	7	27,843,773 (GRCm39)	missense	possibly damaging	0.52
R1971:Fcgbpl1	UTSW	7	27,830,937 (GRCm39)	missense	possibly damaging	0.90
R1990:Fcgbpl1	UTSW	7	27,853,785 (GRCm39)	missense	probably damaging	0.98
R2020:Fcgbpl1	UTSW	7	27,855,019 (GRCm39)	missense	probably benign
R2084:Fcgbpl1	UTSW	7	27,856,960 (GRCm39)	missense	probably damaging	1.00
R2125:Fcgbpl1	UTSW	7	27,857,447 (GRCm39)	missense	probably benign	0.00
R2132:Fcgbpl1	UTSW	7	27,854,899 (GRCm39)	missense	probably damaging	1.00
R2513:Fcgbpl1	UTSW	7	27,831,060 (GRCm39)	missense	probably damaging	0.99
R2913:Fcgbpl1	UTSW	7	27,863,732 (GRCm39)	missense	probably damaging	1.00
R3150:Fcgbpl1	UTSW	7	27,853,620 (GRCm39)	missense	probably benign	0.21
R3499:Fcgbpl1	UTSW	7	27,853,980 (GRCm39)	missense	probably benign	0.42
R3702:Fcgbpl1	UTSW	7	27,857,203 (GRCm39)	missense	probably damaging	1.00
R3881:Fcgbpl1	UTSW	7	27,839,463 (GRCm39)	nonsense	probably null
R3938:Fcgbpl1	UTSW	7	27,853,719 (GRCm39)	missense	probably damaging	1.00
R4050:Fcgbpl1	UTSW	7	27,852,410 (GRCm39)	missense	possibly damaging	0.55
R4152:Fcgbpl1	UTSW	7	27,856,322 (GRCm39)	missense	possibly damaging	0.47
R4168:Fcgbpl1	UTSW	7	27,836,534 (GRCm39)	missense	probably benign	0.05
R4235:Fcgbpl1	UTSW	7	27,856,073 (GRCm39)	missense	probably damaging	0.99
R4241:Fcgbpl1	UTSW	7	27,853,760 (GRCm39)	missense	probably damaging	1.00
R4363:Fcgbpl1	UTSW	7	27,846,331 (GRCm39)	missense	probably damaging	1.00
R4460:Fcgbpl1	UTSW	7	27,852,281 (GRCm39)	missense	probably benign	0.17
R4463:Fcgbpl1	UTSW	7	27,850,144 (GRCm39)	missense	probably benign
R4841:Fcgbpl1	UTSW	7	27,850,147 (GRCm39)	missense	probably damaging	1.00
R4842:Fcgbpl1	UTSW	7	27,850,147 (GRCm39)	missense	probably damaging	1.00
R4876:Fcgbpl1	UTSW	7	27,842,225 (GRCm39)	intron	probably benign
R4905:Fcgbpl1	UTSW	7	27,856,408 (GRCm39)	missense	possibly damaging	0.93
R4997:Fcgbpl1	UTSW	7	27,843,349 (GRCm39)	missense	possibly damaging	0.77
R5091:Fcgbpl1	UTSW	7	27,856,383 (GRCm39)	missense	probably benign	0.44
R5159:Fcgbpl1	UTSW	7	27,852,733 (GRCm39)	missense	probably benign	0.09
R5326:Fcgbpl1	UTSW	7	27,854,914 (GRCm39)	missense	probably damaging	0.98
R5396:Fcgbpl1	UTSW	7	27,839,608 (GRCm39)	missense	probably benign
R5441:Fcgbpl1	UTSW	7	27,856,339 (GRCm39)	missense	probably damaging	1.00
R5480:Fcgbpl1	UTSW	7	27,857,424 (GRCm39)	nonsense	probably null
R5542:Fcgbpl1	UTSW	7	27,854,914 (GRCm39)	missense	probably damaging	0.98
R5571:Fcgbpl1	UTSW	7	27,855,994 (GRCm39)	missense	probably damaging	0.99
R5613:Fcgbpl1	UTSW	7	27,842,303 (GRCm39)	intron	probably benign
R5637:Fcgbpl1	UTSW	7	27,852,277 (GRCm39)	missense	probably benign	0.00
R5766:Fcgbpl1	UTSW	7	27,836,754 (GRCm39)	nonsense	probably null
R6174:Fcgbpl1	UTSW	7	27,839,384 (GRCm39)	missense	probably damaging	0.96
R6233:Fcgbpl1	UTSW	7	27,830,885 (GRCm39)	missense	probably damaging	0.99
R6250:Fcgbpl1	UTSW	7	27,850,139 (GRCm39)	missense	probably damaging	1.00
R6379:Fcgbpl1	UTSW	7	27,857,017 (GRCm39)	missense	probably damaging	1.00
R6442:Fcgbpl1	UTSW	7	27,843,611 (GRCm39)	missense	possibly damaging	0.88
R6478:Fcgbpl1	UTSW	7	27,854,798 (GRCm39)	missense	probably damaging	1.00
R6699:Fcgbpl1	UTSW	7	27,843,793 (GRCm39)	missense	probably damaging	1.00
R6852:Fcgbpl1	UTSW	7	27,846,560 (GRCm39)	missense	probably damaging	1.00
R6883:Fcgbpl1	UTSW	7	27,852,260 (GRCm39)	missense	possibly damaging	0.89
R6902:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6903:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6904:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6992:Fcgbpl1	UTSW	7	27,839,608 (GRCm39)	missense	probably benign	0.04
R7023:Fcgbpl1	UTSW	7	27,839,463 (GRCm39)	nonsense	probably null
R7039:Fcgbpl1	UTSW	7	27,839,573 (GRCm39)	missense	possibly damaging	0.80
R7171:Fcgbpl1	UTSW	7	27,853,944 (GRCm39)	nonsense	probably null
R7282:Fcgbpl1	UTSW	7	27,843,833 (GRCm39)	missense	probably benign	0.02
R7291:Fcgbpl1	UTSW	7	27,839,645 (GRCm39)	missense	probably benign
R7344:Fcgbpl1	UTSW	7	27,852,185 (GRCm39)	missense	possibly damaging	0.46
R7344:Fcgbpl1	UTSW	7	27,839,704 (GRCm39)	missense	possibly damaging	0.79
R7392:Fcgbpl1	UTSW	7	27,863,797 (GRCm39)	missense	possibly damaging	0.83
R7531:Fcgbpl1	UTSW	7	27,839,656 (GRCm39)	missense	probably benign
R7541:Fcgbpl1	UTSW	7	27,843,681 (GRCm39)	nonsense	probably null
R7577:Fcgbpl1	UTSW	7	27,853,848 (GRCm39)	missense	possibly damaging	0.65
R7594:Fcgbpl1	UTSW	7	27,830,885 (GRCm39)	missense	probably damaging	0.99
R7647:Fcgbpl1	UTSW	7	27,839,470 (GRCm39)	missense	probably benign	0.00
R7718:Fcgbpl1	UTSW	7	27,846,626 (GRCm39)	missense	probably damaging	1.00
R7733:Fcgbpl1	UTSW	7	27,839,390 (GRCm39)	missense	probably damaging	1.00
R7737:Fcgbpl1	UTSW	7	27,856,498 (GRCm39)	missense	probably damaging	1.00
R7908:Fcgbpl1	UTSW	7	27,846,921 (GRCm39)	missense	probably benign	0.12
R8013:Fcgbpl1	UTSW	7	27,836,966 (GRCm39)	missense	probably benign	0.14
R8014:Fcgbpl1	UTSW	7	27,836,966 (GRCm39)	missense	probably benign	0.14
R8151:Fcgbpl1	UTSW	7	27,852,766 (GRCm39)	missense	possibly damaging	0.95
R8175:Fcgbpl1	UTSW	7	27,863,873 (GRCm39)	nonsense	probably null
R8254:Fcgbpl1	UTSW	7	27,846,774 (GRCm39)	missense	possibly damaging	0.63
R8345:Fcgbpl1	UTSW	7	27,854,785 (GRCm39)	missense	probably damaging	1.00
R8414:Fcgbpl1	UTSW	7	27,842,158 (GRCm39)	missense	probably damaging	1.00
R8419:Fcgbpl1	UTSW	7	27,843,346 (GRCm39)	missense	probably damaging	1.00
R8496:Fcgbpl1	UTSW	7	27,843,377 (GRCm39)	missense	possibly damaging	0.81
R8691:Fcgbpl1	UTSW	7	27,853,264 (GRCm39)	missense	possibly damaging	0.72
R8785:Fcgbpl1	UTSW	7	27,854,132 (GRCm39)	missense	probably damaging	1.00
R8863:Fcgbpl1	UTSW	7	27,831,006 (GRCm39)	missense	probably damaging	1.00
R8926:Fcgbpl1	UTSW	7	27,853,869 (GRCm39)	missense	probably damaging	1.00
R8950:Fcgbpl1	UTSW	7	27,863,751 (GRCm39)	missense	probably benign	0.32
R9014:Fcgbpl1	UTSW	7	27,854,876 (GRCm39)	missense	probably damaging	1.00
R9045:Fcgbpl1	UTSW	7	27,853,856 (GRCm39)	missense	probably damaging	1.00
R9115:Fcgbpl1	UTSW	7	27,853,754 (GRCm39)	missense	possibly damaging	0.74
R9233:Fcgbpl1	UTSW	7	27,839,519 (GRCm39)	missense	possibly damaging	0.83
R9330:Fcgbpl1	UTSW	7	27,856,410 (GRCm39)	missense	probably benign	0.02
R9426:Fcgbpl1	UTSW	7	27,843,281 (GRCm39)	missense	possibly damaging	0.92
R9477:Fcgbpl1	UTSW	7	27,852,265 (GRCm39)	missense	probably damaging	1.00
R9502:Fcgbpl1	UTSW	7	27,836,891 (GRCm39)	missense	probably benign	0.09
R9505:Fcgbpl1	UTSW	7	27,841,909 (GRCm39)	nonsense	probably null
R9601:Fcgbpl1	UTSW	7	27,853,805 (GRCm39)	missense	possibly damaging	0.78
R9630:Fcgbpl1	UTSW	7	27,836,624 (GRCm39)	missense	probably damaging	1.00
R9632:Fcgbpl1	UTSW	7	27,841,726 (GRCm39)	missense	probably benign
R9673:Fcgbpl1	UTSW	7	27,856,044 (GRCm39)	missense	probably benign	0.25
R9735:Fcgbpl1	UTSW	7	27,856,435 (GRCm39)	missense	probably damaging	1.00
Z1176:Fcgbpl1	UTSW	7	27,854,187 (GRCm39)	missense	probably benign	0.03
Z1176:Fcgbpl1	UTSW	7	27,841,811 (GRCm39)	missense	probably benign	0.06
Z1177:Fcgbpl1	UTSW	7	27,839,323 (GRCm39)	missense	probably benign	0.25
Z1186:Fcgbpl1	UTSW	7	27,856,411 (GRCm39)	missense	probably benign	0.01
Z1186:Fcgbpl1	UTSW	7	27,846,130 (GRCm39)	missense	probably benign	0.00
Z1186:Fcgbpl1	UTSW	7	27,830,997 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- TGACTCCTTGGTCTGCAAGC -3'
(R):5'- TAAGCTGAACCGGTCTCACAC -3'

Sequencing Primer
(F):5'- GAGATCGGCTGCCAACCTATAAG -3'
(R):5'- ACACTCCCGCCATGCTG -3'

Posted On

2014-06-23