Mutagenetix > Incidental Mutation

Incidental Mutation 'R3004:Gm21903'

257401

Institutional Source

Beutler Lab

Gene Symbol

Gm21903

Ensembl Gene

ENSMUSG00000094168

Gene Name

predicted gene, 21903

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

R3004 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

39353525-39354232 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

A to T at 39353547 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000137640 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000178039] [ENSMUST00000180245]

AlphaFold

J3QMQ1

Predicted Effect

unknown
Transcript: ENSMUST00000178039
AA Change: V23D

Predicted Effect

probably benign
Transcript: ENSMUST00000180245

SMART Domains

Protein: ENSMUSP00000137640
Gene: ENSMUSG00000095625

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
Pfam:ESP	24	63	3e-11	PFAM

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.0%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 22 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Alpk3	G	A	7: 80,753,103 (GRCm39)	W1553*	probably null	Het
Art2a	T	C	7: 101,203,972 (GRCm39)	I189V	probably benign	Het
BC049715	A	G	6: 136,816,790 (GRCm39)	E10G	possibly damaging	Het
Ccdc158	A	G	5: 92,796,929 (GRCm39)	L469P	probably damaging	Het
Cspg4b	T	C	13: 113,502,688 (GRCm39)	F131S	probably damaging	Het
Ctsm	T	C	13: 61,687,682 (GRCm39)	I59V	possibly damaging	Het
Daam2	A	G	17: 49,767,682 (GRCm39)	F970L	probably damaging	Het
Gpr158	T	A	2: 21,831,810 (GRCm39)	M970K	probably damaging	Het
H2bc7	G	A	13: 23,758,355 (GRCm39)		probably benign	Het
Hoxd10	T	A	2: 74,522,706 (GRCm39)	V128D	probably benign	Het
Ighv5-9	T	C	12: 113,625,567 (GRCm39)	T59A	probably benign	Het
Nlrp4c	G	A	7: 6,068,524 (GRCm39)	V142M	probably benign	Het
Npc1	A	G	18: 12,330,311 (GRCm39)	F947L	probably benign	Het
Or1ak2	T	A	2: 36,827,221 (GRCm39)	I30N	possibly damaging	Het
Or56b1b	G	T	7: 108,164,151 (GRCm39)	H284N	probably benign	Het
Piezo2	G	T	18: 63,157,506 (GRCm39)	Y223*	probably null	Het
Rhog	A	T	7: 101,889,345 (GRCm39)	V36E	probably damaging	Het
Sbno1	G	A	5: 124,519,771 (GRCm39)	T1168I	probably damaging	Het
Sin3a	T	A	9: 57,004,118 (GRCm39)	L290*	probably null	Het
Slco1c1	G	T	6: 141,478,380 (GRCm39)	A48S	probably damaging	Het
Slfn9	A	T	11: 82,872,590 (GRCm39)	S715R	possibly damaging	Het
Sox17	T	C	1: 4,562,840 (GRCm39)	E120G	probably damaging	Het

Other mutations in Gm21903

Allele	Source	Chr	Coord	Type	Predicted Effect
R8357:Gm21903	UTSW	17	39,354,211 (GRCm39)	missense	unknown
R8457:Gm21903	UTSW	17	39,354,211 (GRCm39)	missense	unknown
R9773:Gm21903	UTSW	17	39,353,541 (GRCm39)	missense	unknown

Predicted Primers

PCR Primer
(F):5'- GAGATAGGACACCCAAATGACT -3'
(R):5'- GGAAACATGAAAGTCTCCCTATGAA -3'

Sequencing Primer
(F):5'- ACCCAAATGACTAACACTATTTCTC -3'
(R):5'- GAAAGTCTCCCTATGAATGAAATTGC -3'

Posted On

2015-01-11