Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02398:Fn1'

291785

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Fn1

Ensembl Gene

ENSMUSG00000026193

Gene Name

fibronectin 1

Synonyms

Fn-1, Fn

Accession Numbers

Is this an essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL02398

Quality Score

Status

Chromosome

Chromosomal Location

71585520-71653200 bp(-) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 71618670 bp

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000140816 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000055226] [ENSMUST00000186129] [ENSMUST00000187938] [ENSMUST00000188674] [ENSMUST00000188894] [ENSMUST00000189821] [ENSMUST00000190780]

Predicted Effect

probably null
Transcript: ENSMUST00000055226

SMART Domains

Protein: ENSMUSP00000054499
Gene: ENSMUSG00000026193

Domain	Start	End	E-Value	Type
low complexity region	2	19	N/A	INTRINSIC
FN1	53	93	6.38e-18	SMART
FN1	98	141	6.04e-19	SMART
FN1	142	185	6.94e-19	SMART
FN1	187	231	3.47e-19	SMART
FN1	232	276	6.04e-19	SMART
FN1	308	347	5.91e-13	SMART
FN2	353	401	6.66e-30	SMART
FN2	413	461	5.05e-30	SMART
FN1	470	513	2.59e-18	SMART
FN1	518	560	1.68e-17	SMART
FN1	561	604	5.69e-15	SMART
FN3	609	688	3.79e-2	SMART
FN3	719	798	1.27e-3	SMART
FN3	810	888	7.92e-14	SMART
FN3	906	985	4.28e-10	SMART
FN3	996	1074	2.53e-12	SMART
FN3	1086	1160	1.31e-5	SMART
FN3	1173	1255	1.13e-9	SMART
FN3	1264	1346	4.22e-9	SMART
FN3	1357	1437	9.6e-13	SMART
FN3	1448	1527	1.82e-13	SMART
FN3	1538	1617	6.69e-12	SMART
FN3	1632	1711	2.72e-12	SMART
FN3	1722	1801	8.9e-8	SMART
FN3	1812	1891	1.66e-7	SMART
FN3	1904	1983	4.92e-10	SMART
FN3	1993	2074	3.64e-13	SMART
low complexity region	2148	2165	N/A	INTRINSIC
FN3	2193	2272	2.9e0	SMART
FN1	2296	2340	3.72e-19	SMART
FN1	2341	2383	2.49e-20	SMART
FN1	2385	2425	2.69e-16	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000186129

SMART Domains

Protein: ENSMUSP00000141123
Gene: ENSMUSG00000026193

Domain	Start	End	E-Value	Type
low complexity region	2	19	N/A	INTRINSIC
FN1	53	93	6.38e-18	SMART
FN1	98	141	6.04e-19	SMART
FN1	142	185	6.94e-19	SMART
FN1	187	231	3.47e-19	SMART
FN1	232	276	6.04e-19	SMART
FN1	308	347	5.91e-13	SMART
FN2	353	401	6.66e-30	SMART
FN2	413	461	5.05e-30	SMART
FN1	470	513	2.59e-18	SMART
FN1	518	560	1.68e-17	SMART
FN1	561	604	5.69e-15	SMART
FN3	609	688	3.79e-2	SMART
FN3	719	798	1.27e-3	SMART
FN3	810	888	7.92e-14	SMART
FN3	906	985	4.28e-10	SMART
FN3	996	1074	2.53e-12	SMART
FN3	1086	1160	1.31e-5	SMART
FN3	1173	1255	1.13e-9	SMART
FN3	1266	1346	9.6e-13	SMART
FN3	1357	1436	1.82e-13	SMART
FN3	1447	1526	6.69e-12	SMART
FN3	1541	1620	2.72e-12	SMART
FN3	1631	1710	1.66e-7	SMART
FN3	1723	1802	4.92e-10	SMART
FN3	1812	1893	3.64e-13	SMART
low complexity region	1967	1984	N/A	INTRINSIC
FN3	2012	2091	2.9e0	SMART
FN1	2115	2159	3.72e-19	SMART
FN1	2160	2202	2.49e-20	SMART
FN1	2204	2244	2.69e-16	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000187938

SMART Domains

Protein: ENSMUSP00000140975
Gene: ENSMUSG00000026193

Domain	Start	End	E-Value	Type
low complexity region	2	19	N/A	INTRINSIC
FN1	53	93	6.38e-18	SMART
FN1	98	141	6.04e-19	SMART
FN1	142	185	6.94e-19	SMART
FN1	187	231	3.47e-19	SMART
FN1	232	276	6.04e-19	SMART
FN1	308	347	5.91e-13	SMART
FN2	353	401	6.66e-30	SMART
FN2	413	461	5.05e-30	SMART
FN1	470	513	2.59e-18	SMART
FN1	518	560	1.68e-17	SMART
FN1	561	604	5.69e-15	SMART
FN3	609	688	3.79e-2	SMART
FN3	719	798	1.27e-3	SMART
FN3	810	888	7.92e-14	SMART
FN3	906	985	4.28e-10	SMART
FN3	996	1074	2.53e-12	SMART
FN3	1086	1160	1.31e-5	SMART
FN3	1173	1255	1.13e-9	SMART
FN3	1266	1346	9.6e-13	SMART
FN3	1357	1436	1.82e-13	SMART
FN3	1447	1526	6.69e-12	SMART
FN3	1541	1620	2.72e-12	SMART
FN3	1631	1710	8.9e-8	SMART
FN3	1721	1800	1.66e-7	SMART
FN3	1813	1892	4.92e-10	SMART
FN3	1902	1983	3.64e-13	SMART
low complexity region	2032	2049	N/A	INTRINSIC
FN3	2077	2156	2.9e0	SMART
FN1	2180	2224	3.72e-19	SMART
FN1	2225	2267	2.49e-20	SMART
FN1	2269	2309	2.69e-16	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000188674

SMART Domains

Protein: ENSMUSP00000140907
Gene: ENSMUSG00000026193

Domain	Start	End	E-Value	Type
low complexity region	2	19	N/A	INTRINSIC
FN1	53	93	6.38e-18	SMART
FN1	98	141	6.04e-19	SMART
FN1	142	185	6.94e-19	SMART
FN1	187	231	3.47e-19	SMART
FN1	232	276	6.04e-19	SMART
FN1	308	347	5.91e-13	SMART
FN2	353	401	6.66e-30	SMART
FN2	413	461	5.05e-30	SMART
FN1	470	513	2.59e-18	SMART
FN1	518	560	1.68e-17	SMART
FN1	561	604	5.69e-15	SMART
FN3	609	688	3.79e-2	SMART
FN3	719	798	1.27e-3	SMART
FN3	810	888	7.92e-14	SMART
FN3	906	985	4.28e-10	SMART
FN3	996	1074	2.53e-12	SMART
FN3	1086	1160	1.31e-5	SMART
FN3	1173	1255	1.13e-9	SMART
FN3	1266	1346	9.6e-13	SMART
FN3	1357	1436	1.82e-13	SMART
FN3	1447	1526	6.69e-12	SMART
FN3	1541	1620	2.72e-12	SMART
FN3	1631	1710	8.9e-8	SMART
FN3	1721	1800	1.66e-7	SMART
FN3	1813	1892	4.92e-10	SMART
FN3	1902	1981	6.79e-13	SMART
FN3	1983	2061	1.01e1	SMART
FN1	2085	2129	3.72e-19	SMART
FN1	2130	2172	2.49e-20	SMART
FN1	2174	2214	2.69e-16	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000188894

SMART Domains

Protein: ENSMUSP00000140471
Gene: ENSMUSG00000026193

Domain	Start	End	E-Value	Type
low complexity region	2	19	N/A	INTRINSIC
FN1	53	93	6.38e-18	SMART
FN1	98	141	6.04e-19	SMART
FN1	142	185	6.94e-19	SMART
FN1	187	231	3.47e-19	SMART
FN1	232	276	6.04e-19	SMART
FN1	308	347	5.91e-13	SMART
FN2	353	401	6.66e-30	SMART
FN2	413	461	5.05e-30	SMART
FN1	470	513	2.59e-18	SMART
FN1	518	560	1.68e-17	SMART
FN1	561	604	5.69e-15	SMART
FN3	609	688	3.79e-2	SMART
FN3	719	798	1.27e-3	SMART
FN3	810	888	7.92e-14	SMART
FN3	906	985	4.28e-10	SMART
FN3	996	1074	2.53e-12	SMART
FN3	1086	1160	1.31e-5	SMART
FN3	1173	1255	1.13e-9	SMART
FN3	1266	1346	9.6e-13	SMART
FN3	1357	1436	1.82e-13	SMART
FN3	1447	1526	6.69e-12	SMART
FN3	1541	1620	2.72e-12	SMART
FN3	1631	1710	8.9e-8	SMART
FN3	1721	1800	1.66e-7	SMART
FN3	1813	1892	4.92e-10	SMART
FN3	1902	1983	3.64e-13	SMART
low complexity region	2057	2074	N/A	INTRINSIC
FN3	2102	2181	2.9e0	SMART
FN1	2205	2249	3.72e-19	SMART
FN1	2250	2292	2.49e-20	SMART
FN1	2294	2334	2.69e-16	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000189160

Predicted Effect

probably null
Transcript: ENSMUST00000189821

SMART Domains

Protein: ENSMUSP00000139702
Gene: ENSMUSG00000026193

Domain	Start	End	E-Value	Type
low complexity region	2	19	N/A	INTRINSIC
FN1	53	93	6.38e-18	SMART
FN1	98	141	6.04e-19	SMART
FN1	142	185	6.94e-19	SMART
FN1	187	231	3.47e-19	SMART
FN1	232	276	6.04e-19	SMART
FN1	308	347	5.91e-13	SMART
FN2	353	401	6.66e-30	SMART
FN2	413	461	5.05e-30	SMART
FN1	470	513	2.59e-18	SMART
FN1	518	560	1.68e-17	SMART
FN1	561	604	5.69e-15	SMART
FN3	609	688	3.79e-2	SMART
FN3	719	798	1.27e-3	SMART
FN3	810	888	7.92e-14	SMART
FN3	906	985	4.28e-10	SMART
FN3	996	1074	2.53e-12	SMART
FN3	1086	1160	1.31e-5	SMART
FN3	1173	1255	1.13e-9	SMART
FN3	1266	1346	9.6e-13	SMART
FN3	1357	1436	1.82e-13	SMART
FN3	1447	1526	6.69e-12	SMART
FN3	1541	1620	2.72e-12	SMART
FN3	1631	1710	1.66e-7	SMART
FN3	1723	1802	4.92e-10	SMART
FN3	1812	1891	6.79e-13	SMART
FN3	1893	1971	1.01e1	SMART
FN1	1995	2039	3.72e-19	SMART
FN1	2040	2082	2.49e-20	SMART
FN1	2084	2124	2.69e-16	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000190780

SMART Domains

Protein: ENSMUSP00000140816
Gene: ENSMUSG00000026193

Domain	Start	End	E-Value	Type
low complexity region	2	19	N/A	INTRINSIC
FN1	53	93	6.38e-18	SMART
FN1	98	141	6.04e-19	SMART
FN1	142	185	6.94e-19	SMART
FN1	187	231	3.47e-19	SMART
FN1	232	276	6.04e-19	SMART
FN1	308	347	5.91e-13	SMART
FN2	353	401	6.66e-30	SMART
FN2	413	461	5.05e-30	SMART
FN1	470	513	2.59e-18	SMART
FN1	518	560	1.68e-17	SMART
FN1	561	604	5.69e-15	SMART
FN3	609	688	3.79e-2	SMART
FN3	719	798	1.27e-3	SMART
FN3	810	888	7.92e-14	SMART
FN3	906	985	4.28e-10	SMART
FN3	996	1074	2.53e-12	SMART
FN3	1086	1160	1.31e-5	SMART
FN3	1173	1255	1.13e-9	SMART
FN3	1266	1346	9.6e-13	SMART
FN3	1357	1436	1.82e-13	SMART
FN3	1447	1526	6.69e-12	SMART
FN3	1541	1620	2.72e-12	SMART
FN3	1631	1710	1.66e-7	SMART
FN3	1723	1802	4.92e-10	SMART
FN3	1812	1893	3.64e-13	SMART
low complexity region	1942	1959	N/A	INTRINSIC
FN3	1987	2066	2.9e0	SMART
FN1	2090	2134	3.72e-19	SMART
FN1	2135	2177	2.49e-20	SMART
FN1	2179	2219	2.69e-16	SMART

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016]
PHENOTYPE: Mutants are defective in mesodermal function. Null mutants are embryonic lethal with major patterning and organizational defects. Conditional mutants live and show increased neuronal apoptosis and susceptibility to induced cerebral ischemia. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 51 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgre1	T	A	17: 57,402,824	C160*	probably null	Het
Alkbh8	C	T	9: 3,345,870	P197S	possibly damaging	Het
Ankef1	A	C	2: 136,555,782	N761T	probably damaging	Het
Ankrd7	A	G	6: 18,866,697	Y72C	probably damaging	Het
Cfap36	T	G	11: 29,222,833	M231L	probably benign	Het
Cog7	A	G	7: 121,964,209	C227R	probably damaging	Het
Csgalnact1	C	A	8: 68,401,492	G219V	probably damaging	Het
Cspg4	A	T	9: 56,886,686	E568D	probably benign	Het
Cwc27	G	A	13: 104,804,254	T199I	possibly damaging	Het
Cyp26a1	A	G	19: 37,700,019	I330V	probably benign	Het
Dcaf7	T	C	11: 106,053,753	V254A	probably benign	Het
Dhrs7	G	A	12: 72,664,692	R24C	probably damaging	Het
Ehmt2	T	A	17: 34,908,479	C838S	probably damaging	Het
Gjb3	T	A	4: 127,326,062	S226C	probably benign	Het
Gm14496	A	G	2: 181,996,170	I346V	probably benign	Het
Gm5926	A	G	X: 32,651,386	D224G	probably damaging	Het
Gm8050	T	C	14: 6,717,330	E172G	probably damaging	Het
Higd1a	G	A	9: 121,852,524	R22W	probably damaging	Het
Hmcn1	A	G	1: 150,802,897	L491S	possibly damaging	Het
Igsf9b	T	C	9: 27,333,130	S794P	possibly damaging	Het
Irgm2	A	T	11: 58,219,929	I161F	probably damaging	Het
Lrp8	G	T	4: 107,847,494	V304F	probably damaging	Het
Lrp8	C	A	4: 107,869,048	S850R	probably damaging	Het
Lrrc9	A	T	12: 72,466,903	M513L	probably benign	Het
Myo18b	A	T	5: 112,830,312	V1248E	possibly damaging	Het
Myo1b	A	T	1: 51,757,891	N945K	probably damaging	Het
Nipbl	A	G	15: 8,327,090	L1604P	probably damaging	Het
Oas1f	A	T	5: 120,851,505	Y169F	probably benign	Het
Ogfod3	G	A	11: 121,203,025	T53I	probably benign	Het
Olfr1054	A	T	2: 86,332,524	Y277*	probably null	Het
Olfr444	A	T	6: 42,956,112	I205F	probably benign	Het
Olfr584	G	A	7: 103,086,106	C191Y	probably damaging	Het
Parp8	A	G	13: 116,910,863		probably null	Het
Pde4dip	T	C	3: 97,766,781	Y273C	probably benign	Het
Pgbd5	C	T	8: 124,384,518	A54T	probably damaging	Het
Pglyrp4	G	A	3: 90,739,117		probably benign	Het
Piezo1	A	T	8: 122,486,563	S1819R	probably benign	Het
Polr1a	T	C	6: 71,936,556		probably benign	Het
Polr1b	A	G	2: 129,102,966	I61V	probably benign	Het
Prlhr	G	T	19: 60,467,315	A271E	probably damaging	Het
Rad23b	C	T	4: 55,350,360		probably benign	Het
Rad51ap1	A	T	6: 126,928,151	S132R	probably damaging	Het
Ros1	T	A	10: 52,144,884		probably benign	Het
Ryr3	T	C	2: 112,847,422	D1327G	probably benign	Het
Slit1	A	C	19: 41,602,237	V1332G	probably damaging	Het
Tmem178b	A	G	6: 40,207,527	M120V	probably damaging	Het
Trim25	T	C	11: 88,999,804	C106R	probably damaging	Het
Trim35	A	G	14: 66,309,248	Y488C	probably damaging	Het
Tsc2	A	T	17: 24,621,729	H326Q	probably damaging	Het
Yap1	A	T	9: 7,950,535	I315K	probably benign	Het
Zfp654	A	G	16: 64,786,018	V607A	probably benign	Het

Other mutations in Fn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00236:Fn1	APN	1	71652873	missense	probably benign	0.28
IGL00402:Fn1	APN	1	71641163	missense	probably damaging	1.00
IGL00946:Fn1	APN	1	71645540	splice site	probably benign
IGL01311:Fn1	APN	1	71628140	missense	probably damaging	1.00
IGL01338:Fn1	APN	1	71626210	missense	probably damaging	0.98
IGL01353:Fn1	APN	1	71586939	missense	probably damaging	1.00
IGL01674:Fn1	APN	1	71606741	missense	probably damaging	1.00
IGL01701:Fn1	APN	1	71629853	splice site	probably benign
IGL01734:Fn1	APN	1	71619485	missense	probably damaging	1.00
IGL01788:Fn1	APN	1	71613837	missense	probably damaging	1.00
IGL02186:Fn1	APN	1	71638534	missense	probably damaging	1.00
IGL02425:Fn1	APN	1	71641143	splice site	probably benign
IGL02516:Fn1	APN	1	71637323	missense	possibly damaging	0.78
IGL02593:Fn1	APN	1	71602432	missense	probably benign
IGL02651:Fn1	APN	1	71597676	missense	possibly damaging	0.65
IGL02681:Fn1	APN	1	71619482	missense	probably damaging	1.00
IGL02890:Fn1	APN	1	71598372	critical splice donor site	probably null
IGL02929:Fn1	APN	1	71595662	critical splice donor site	probably null
IGL03036:Fn1	APN	1	71629773	missense	probably damaging	1.00
IGL03088:Fn1	APN	1	71614038	splice site	probably null
IGL03142:Fn1	APN	1	71637296	missense	probably damaging	1.00
IGL03172:Fn1	APN	1	71641262	missense	probably damaging	0.99
IGL03184:Fn1	APN	1	71609497	missense	probably benign	0.02
IGL03212:Fn1	APN	1	71641325	nonsense	probably null
IGL03246:Fn1	APN	1	71624296	missense	possibly damaging	0.89
IGL03367:Fn1	APN	1	71597553	missense	probably benign	0.27
PIT4514001:Fn1	UTSW	1	71628456	missense	probably benign	0.01
R0008:Fn1	UTSW	1	71595720	missense	probably damaging	0.98
R0112:Fn1	UTSW	1	71609653	missense	probably damaging	1.00
R0138:Fn1	UTSW	1	71624110	missense	possibly damaging	0.82
R0383:Fn1	UTSW	1	71597685	missense	probably damaging	0.99
R0386:Fn1	UTSW	1	71595786	missense	probably damaging	1.00
R0648:Fn1	UTSW	1	71597585	missense	possibly damaging	0.79
R0684:Fn1	UTSW	1	71595809	splice site	probably null
R1054:Fn1	UTSW	1	71586214	makesense	probably null
R1183:Fn1	UTSW	1	71586245	missense	probably damaging	0.98
R1405:Fn1	UTSW	1	71642078	missense	probably damaging	1.00
R1405:Fn1	UTSW	1	71642078	missense	probably damaging	1.00
R1414:Fn1	UTSW	1	71601303	splice site	probably benign
R1677:Fn1	UTSW	1	71597655	missense	probably benign	0.00
R1773:Fn1	UTSW	1	71637383	missense	probably damaging	1.00
R1830:Fn1	UTSW	1	71624259	missense	probably damaging	1.00
R1987:Fn1	UTSW	1	71651625	missense	probably damaging	1.00
R1989:Fn1	UTSW	1	71651625	missense	probably damaging	1.00
R2068:Fn1	UTSW	1	71600439	missense	probably damaging	1.00
R2113:Fn1	UTSW	1	71626164	missense	probably damaging	1.00
R2145:Fn1	UTSW	1	71606004	missense	probably damaging	1.00
R2246:Fn1	UTSW	1	71628535	missense	probably benign	0.10
R2273:Fn1	UTSW	1	71613943	missense	probably null	1.00
R2274:Fn1	UTSW	1	71613943	missense	probably null	1.00
R2275:Fn1	UTSW	1	71613943	missense	probably null	1.00
R2303:Fn1	UTSW	1	71614036	critical splice acceptor site	probably null
R2379:Fn1	UTSW	1	71649284	nonsense	probably null
R2382:Fn1	UTSW	1	71648119	missense	probably damaging	1.00
R2567:Fn1	UTSW	1	71597736	nonsense	probably null
R2864:Fn1	UTSW	1	71602419	missense	probably damaging	0.99
R3154:Fn1	UTSW	1	71593083	missense	probably damaging	1.00
R3837:Fn1	UTSW	1	71653155	splice site	probably null
R3844:Fn1	UTSW	1	71609574	missense	possibly damaging	0.61
R3886:Fn1	UTSW	1	71640306	missense	probably damaging	1.00
R3887:Fn1	UTSW	1	71640306	missense	probably damaging	1.00
R3888:Fn1	UTSW	1	71640306	missense	probably damaging	1.00
R3889:Fn1	UTSW	1	71640306	missense	probably damaging	1.00
R3905:Fn1	UTSW	1	71607913	missense	probably damaging	1.00
R3906:Fn1	UTSW	1	71607913	missense	probably damaging	1.00
R3907:Fn1	UTSW	1	71607913	missense	probably damaging	1.00
R3909:Fn1	UTSW	1	71607913	missense	probably damaging	1.00
R4611:Fn1	UTSW	1	71624178	nonsense	probably null
R4724:Fn1	UTSW	1	71648148	critical splice acceptor site	probably null
R4732:Fn1	UTSW	1	71602512	splice site	probably null
R4733:Fn1	UTSW	1	71602512	splice site	probably null
R4756:Fn1	UTSW	1	71590808	missense	probably damaging	1.00
R4809:Fn1	UTSW	1	71652800	intron	probably benign
R4839:Fn1	UTSW	1	71642083	missense	probably damaging	1.00
R4915:Fn1	UTSW	1	71595809	splice site	probably null
R4917:Fn1	UTSW	1	71595809	splice site	probably null
R4918:Fn1	UTSW	1	71595809	splice site	probably null
R5002:Fn1	UTSW	1	71629728	missense	possibly damaging	0.48
R5015:Fn1	UTSW	1	71626177	missense	probably damaging	0.98
R5022:Fn1	UTSW	1	71624179	missense	probably damaging	1.00
R5109:Fn1	UTSW	1	71649235	missense	probably damaging	1.00
R5267:Fn1	UTSW	1	71629704	missense	probably damaging	1.00
R5323:Fn1	UTSW	1	71597432	missense	probably benign	0.09
R5333:Fn1	UTSW	1	71624180	missense	probably damaging	1.00
R5631:Fn1	UTSW	1	71590196	missense	probably damaging	1.00
R5644:Fn1	UTSW	1	71627250	missense	probably damaging	1.00
R5754:Fn1	UTSW	1	71600322	missense	probably damaging	1.00
R5807:Fn1	UTSW	1	71648059	missense	probably damaging	1.00
R6053:Fn1	UTSW	1	71599290	missense	probably damaging	1.00
R6133:Fn1	UTSW	1	71597727	missense	probably damaging	1.00
R6186:Fn1	UTSW	1	71637290	missense	probably damaging	1.00
R6270:Fn1	UTSW	1	71637275	missense	probably damaging	1.00
R6332:Fn1	UTSW	1	71628071	missense	probably benign	0.01
R6431:Fn1	UTSW	1	71647844	splice site	probably null
R6571:Fn1	UTSW	1	71626190	missense	probably damaging	1.00
R6596:Fn1	UTSW	1	71609482	missense	probably damaging	1.00
R6862:Fn1	UTSW	1	71613907	missense	probably benign	0.43
R6898:Fn1	UTSW	1	71600413	missense	probably damaging	1.00
R6984:Fn1	UTSW	1	71626079	missense	probably damaging	1.00
R7107:Fn1	UTSW	1	71627249	missense	probably damaging	1.00
R7121:Fn1	UTSW	1	71600538	intron	probably benign
R7127:Fn1	UTSW	1	71597544	missense	probably benign	0.16
R7194:Fn1	UTSW	1	71602323	missense	probably damaging	1.00
R7274:Fn1	UTSW	1	71628113	missense	probably benign
R7285:Fn1	UTSW	1	71637339	missense	probably damaging	1.00
R7426:Fn1	UTSW	1	71649225	missense	probably damaging	1.00
R7453:Fn1	UTSW	1	71590880	missense	probably damaging	1.00
R7508:Fn1	UTSW	1	71597516	missense	probably benign	0.01
R7724:Fn1	UTSW	1	71603735	missense	probably benign	0.02
R7848:Fn1	UTSW	1	71650601	missense	probably damaging	1.00
R7992:Fn1	UTSW	1	71599666	missense	probably benign	0.34
R8036:Fn1	UTSW	1	71590151	nonsense	probably null
R8077:Fn1	UTSW	1	71612602	missense	probably damaging	1.00
R8175:Fn1	UTSW	1	71599665	missense	probably damaging	1.00
R8177:Fn1	UTSW	1	71609587	missense	probably benign
R8212:Fn1	UTSW	1	71642905	missense	probably benign	0.01
R8322:Fn1	UTSW	1	71628459	missense	probably benign	0.04
X0023:Fn1	UTSW	1	71598373	critical splice donor site	probably null
Z1088:Fn1	UTSW	1	71649292	missense	probably damaging	1.00
Z1176:Fn1	UTSW	1	71597411	missense	probably benign	0.10

Posted On

2015-04-16