Incidental Mutation 'R4964:Caskin1'
| ID |
383842 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Caskin1
|
| Ensembl Gene |
ENSMUSG00000033597 |
| Gene Name |
CASK interacting protein 1 |
| Synonyms |
3300002N10Rik, C630036E02Rik |
| MMRRC Submission |
042561-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.114)
|
| Stock # |
R4964 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
24707575-24727645 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 24726135 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 1414
(D1414V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000024958
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000024958]
[ENSMUST00000070777]
[ENSMUST00000088464]
[ENSMUST00000176086]
[ENSMUST00000176353]
[ENSMUST00000176668]
[ENSMUST00000176652]
|
| AlphaFold |
Q6P9K8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000024958
AA Change: D1414V
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000024958
Gene: ENSMUSG00000033597
AA Change: D1414V
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
48 |
77 |
9.93e-5 |
SMART |
|
ANK
|
81 |
110 |
1.9e-1 |
SMART |
|
ANK
|
114 |
143 |
1.51e-4 |
SMART |
|
ANK
|
147 |
176 |
1.15e0 |
SMART |
|
ANK
|
188 |
217 |
2.6e-8 |
SMART |
|
ANK
|
220 |
249 |
3.31e-1 |
SMART |
|
SH3
|
284 |
346 |
3.62e-5 |
SMART |
|
Pfam:Caskin1-CID
|
373 |
421 |
3e-26 |
PFAM |
|
SAM
|
473 |
539 |
3.63e-15 |
SMART |
|
SAM
|
542 |
609 |
5.41e-14 |
SMART |
|
low complexity region
|
631 |
647 |
N/A |
INTRINSIC |
|
low complexity region
|
667 |
679 |
N/A |
INTRINSIC |
|
low complexity region
|
715 |
724 |
N/A |
INTRINSIC |
|
low complexity region
|
841 |
863 |
N/A |
INTRINSIC |
|
Pfam:Caskin-Pro-rich
|
878 |
966 |
3e-37 |
PFAM |
|
low complexity region
|
1163 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1190 |
1216 |
N/A |
INTRINSIC |
|
low complexity region
|
1222 |
1232 |
N/A |
INTRINSIC |
|
low complexity region
|
1269 |
1288 |
N/A |
INTRINSIC |
|
low complexity region
|
1294 |
1312 |
N/A |
INTRINSIC |
|
low complexity region
|
1315 |
1333 |
N/A |
INTRINSIC |
|
low complexity region
|
1344 |
1359 |
N/A |
INTRINSIC |
|
Pfam:Caskin-tail
|
1369 |
1431 |
7.2e-33 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000070777
|
| SMART Domains |
Protein: ENSMUSP00000069334
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
RING
|
92 |
125 |
4.73e-6 |
SMART |
|
coiled coil region
|
264 |
332 |
N/A |
INTRINSIC |
|
WD40
|
344 |
383 |
8.35e-11 |
SMART |
|
WD40
|
387 |
424 |
8.42e-7 |
SMART |
|
WD40
|
427 |
463 |
2.09e-2 |
SMART |
|
WD40
|
468 |
504 |
1.92e0 |
SMART |
|
WD40
|
507 |
544 |
5.15e-2 |
SMART |
|
WD40
|
547 |
588 |
1.78e-5 |
SMART |
|
WD40
|
591 |
628 |
1.63e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000088464
|
| SMART Domains |
Protein: ENSMUSP00000085812
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
117 |
N/A |
INTRINSIC |
|
RING
|
130 |
163 |
4.73e-6 |
SMART |
|
Pfam:zf-TRAF
|
221 |
277 |
3.4e-8 |
PFAM |
|
coiled coil region
|
304 |
372 |
N/A |
INTRINSIC |
|
WD40
|
384 |
423 |
8.35e-11 |
SMART |
|
WD40
|
427 |
464 |
8.42e-7 |
SMART |
|
WD40
|
467 |
503 |
2.09e-2 |
SMART |
|
WD40
|
508 |
544 |
1.92e0 |
SMART |
|
WD40
|
547 |
584 |
5.15e-2 |
SMART |
|
WD40
|
587 |
628 |
1.78e-5 |
SMART |
|
WD40
|
631 |
668 |
1.63e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000175698
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000175732
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176086
|
| SMART Domains |
Protein: ENSMUSP00000135845
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
103 |
132 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176353
|
| SMART Domains |
Protein: ENSMUSP00000135267
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
RING
|
92 |
125 |
4.73e-6 |
SMART |
|
coiled coil region
|
264 |
332 |
N/A |
INTRINSIC |
|
WD40
|
344 |
383 |
8.35e-11 |
SMART |
|
WD40
|
387 |
424 |
8.42e-7 |
SMART |
|
WD40
|
427 |
463 |
2.09e-2 |
SMART |
|
WD40
|
468 |
504 |
1.92e0 |
SMART |
|
WD40
|
507 |
544 |
5.15e-2 |
SMART |
|
WD40
|
547 |
588 |
1.78e-5 |
SMART |
|
WD40
|
591 |
628 |
1.63e-4 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176805
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000177024
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176900
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176530
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177502
|
| SMART Domains |
Protein: ENSMUSP00000134970
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
11 |
N/A |
INTRINSIC |
|
RING
|
24 |
68 |
4.24e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176668
|
| SMART Domains |
Protein: ENSMUSP00000135586
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176652
|
| SMART Domains |
Protein: ENSMUSP00000134759
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
117 |
N/A |
INTRINSIC |
|
RING
|
130 |
163 |
4.73e-6 |
SMART |
|
coiled coil region
|
304 |
372 |
N/A |
INTRINSIC |
|
WD40
|
384 |
423 |
8.35e-11 |
SMART |
|
WD40
|
427 |
464 |
8.42e-7 |
SMART |
|
WD40
|
467 |
503 |
2.09e-2 |
SMART |
|
WD40
|
508 |
544 |
1.92e0 |
SMART |
|
WD40
|
547 |
584 |
5.15e-2 |
SMART |
|
WD40
|
587 |
628 |
1.78e-5 |
SMART |
|
WD40
|
631 |
668 |
1.63e-4 |
SMART |
|
| Meta Mutation Damage Score |
0.3496 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.0%
|
| Validation Efficiency |
98% (100/102) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4833420G17Rik |
T |
C |
13: 119,610,757 (GRCm39) |
|
probably benign |
Het |
| 9030619P08Rik |
T |
A |
15: 75,303,267 (GRCm39) |
|
noncoding transcript |
Het |
| A430033K04Rik |
G |
T |
5: 138,645,119 (GRCm39) |
E335* |
probably null |
Het |
| Abcb1b |
A |
T |
5: 8,862,671 (GRCm39) |
T118S |
probably benign |
Het |
| Abcb1b |
T |
A |
5: 8,911,602 (GRCm39) |
I133N |
probably damaging |
Het |
| Acox3 |
A |
G |
5: 35,747,080 (GRCm39) |
N166D |
probably damaging |
Het |
| Adam5 |
T |
C |
8: 25,276,248 (GRCm39) |
Y473C |
probably damaging |
Het |
| Ankmy2 |
A |
G |
12: 36,236,917 (GRCm39) |
K242E |
possibly damaging |
Het |
| Apc2 |
A |
C |
10: 80,149,841 (GRCm39) |
I1603L |
probably benign |
Het |
| Arhgef25 |
T |
A |
10: 127,021,472 (GRCm39) |
I249F |
probably damaging |
Het |
| Birc2 |
T |
C |
9: 7,860,553 (GRCm39) |
H255R |
probably benign |
Het |
| Cables1 |
A |
T |
18: 12,074,334 (GRCm39) |
R486W |
possibly damaging |
Het |
| Ccdc175 |
A |
G |
12: 72,227,619 (GRCm39) |
S55P |
probably damaging |
Het |
| Ccdc57 |
A |
T |
11: 120,751,978 (GRCm39) |
S868T |
probably benign |
Het |
| Ccny |
A |
T |
18: 9,449,516 (GRCm39) |
|
probably null |
Het |
| Cdc34b |
A |
T |
11: 94,633,087 (GRCm39) |
I96F |
probably damaging |
Het |
| Ctnnd1 |
A |
G |
2: 84,452,417 (GRCm39) |
F69L |
possibly damaging |
Het |
| Cul9 |
C |
T |
17: 46,849,451 (GRCm39) |
D565N |
probably damaging |
Het |
| Cxcl16 |
A |
G |
11: 70,346,519 (GRCm39) |
V208A |
probably benign |
Het |
| Cyb5rl |
A |
G |
4: 106,926,329 (GRCm39) |
|
probably benign |
Het |
| Ddx18 |
T |
C |
1: 121,493,823 (GRCm39) |
K54E |
probably benign |
Het |
| Ddx60 |
G |
A |
8: 62,432,372 (GRCm39) |
V885I |
probably damaging |
Het |
| Dlg1 |
C |
T |
16: 31,573,626 (GRCm39) |
T9I |
probably benign |
Het |
| Dnase1 |
T |
C |
16: 3,855,771 (GRCm39) |
|
probably benign |
Het |
| Drd4 |
T |
C |
7: 140,873,690 (GRCm39) |
M114T |
probably damaging |
Het |
| Egfr |
A |
T |
11: 16,858,949 (GRCm39) |
D976V |
probably damaging |
Het |
| Eif2s1 |
T |
A |
12: 78,926,785 (GRCm39) |
N178K |
probably benign |
Het |
| Exoc3l4 |
A |
G |
12: 111,395,155 (GRCm39) |
H591R |
probably benign |
Het |
| Galntl6 |
T |
C |
8: 59,152,945 (GRCm39) |
|
probably benign |
Het |
| Glipr1l2 |
T |
A |
10: 111,942,904 (GRCm39) |
I253K |
possibly damaging |
Het |
| Gnat1 |
A |
T |
9: 107,554,433 (GRCm39) |
M115K |
probably benign |
Het |
| Gtsf2 |
T |
C |
15: 103,352,755 (GRCm39) |
E88G |
possibly damaging |
Het |
| Hormad1 |
T |
A |
3: 95,492,531 (GRCm39) |
|
probably null |
Het |
| Hydin |
A |
T |
8: 111,217,305 (GRCm39) |
I1398F |
possibly damaging |
Het |
| Ifnar1 |
T |
C |
16: 91,301,974 (GRCm39) |
V483A |
probably benign |
Het |
| Ints11 |
T |
C |
4: 155,971,385 (GRCm39) |
F278L |
probably damaging |
Het |
| Ints6 |
A |
G |
14: 62,939,911 (GRCm39) |
L593P |
probably damaging |
Het |
| Krt7 |
C |
T |
15: 101,311,853 (GRCm39) |
R104C |
probably damaging |
Het |
| Map4k1 |
A |
T |
7: 28,682,427 (GRCm39) |
H16L |
probably benign |
Het |
| Mef2d |
T |
A |
3: 88,075,404 (GRCm39) |
I422N |
probably damaging |
Het |
| Mipep |
G |
T |
14: 61,022,231 (GRCm39) |
R32L |
probably damaging |
Het |
| Mon1a |
A |
G |
9: 107,779,850 (GRCm39) |
E473G |
probably damaging |
Het |
| Mterf2 |
T |
A |
10: 84,955,979 (GRCm39) |
Q215L |
probably damaging |
Het |
| Mybpc1 |
T |
A |
10: 88,391,525 (GRCm39) |
Y324F |
probably benign |
Het |
| Myh11 |
T |
C |
16: 14,023,818 (GRCm39) |
E1512G |
probably damaging |
Het |
| Myo1g |
A |
T |
11: 6,465,976 (GRCm39) |
F370I |
probably damaging |
Het |
| Myo5c |
T |
A |
9: 75,204,791 (GRCm39) |
M1548K |
possibly damaging |
Het |
| Myof |
T |
A |
19: 37,924,300 (GRCm39) |
I1306F |
probably damaging |
Het |
| Nle1 |
A |
G |
11: 82,799,018 (GRCm39) |
F21S |
probably damaging |
Het |
| Noc2l |
C |
G |
4: 156,330,368 (GRCm39) |
D513E |
probably damaging |
Het |
| Or1e17 |
A |
T |
11: 73,832,028 (GRCm39) |
I319F |
probably benign |
Het |
| Or2z2 |
A |
G |
11: 58,346,733 (GRCm39) |
V14A |
probably benign |
Het |
| Orc1 |
T |
C |
4: 108,471,670 (GRCm39) |
*841R |
probably null |
Het |
| Patz1 |
A |
G |
11: 3,257,720 (GRCm39) |
D573G |
probably damaging |
Het |
| Pcdhga3 |
A |
G |
18: 37,809,154 (GRCm39) |
T536A |
probably benign |
Het |
| Pde6h |
C |
T |
6: 136,938,201 (GRCm39) |
T58I |
possibly damaging |
Het |
| Pip5k1a |
T |
C |
3: 94,978,094 (GRCm39) |
I275V |
probably benign |
Het |
| Pkd1 |
T |
C |
17: 24,805,042 (GRCm39) |
|
probably null |
Het |
| Polr1e |
G |
A |
4: 45,029,429 (GRCm39) |
A297T |
probably damaging |
Het |
| Polrmt |
A |
G |
10: 79,582,385 (GRCm39) |
M1T |
probably null |
Het |
| Rbm34 |
T |
C |
8: 127,678,087 (GRCm39) |
D269G |
possibly damaging |
Het |
| Rnf122 |
T |
A |
8: 31,602,177 (GRCm39) |
M1K |
probably null |
Het |
| Rnf32 |
G |
A |
5: 29,403,576 (GRCm39) |
R7H |
probably benign |
Het |
| Ryr2 |
T |
C |
13: 11,729,497 (GRCm39) |
E2375G |
possibly damaging |
Het |
| Ryr2 |
T |
C |
13: 11,848,878 (GRCm39) |
T361A |
probably benign |
Het |
| Serpina3m |
T |
C |
12: 104,355,360 (GRCm39) |
I9T |
probably benign |
Het |
| Serpinb9 |
T |
A |
13: 33,192,847 (GRCm39) |
W135R |
probably damaging |
Het |
| Sf3b1 |
T |
C |
1: 55,038,871 (GRCm39) |
N804S |
probably benign |
Het |
| Shroom1 |
A |
G |
11: 53,355,999 (GRCm39) |
T350A |
probably benign |
Het |
| Slc24a5 |
G |
A |
2: 124,910,188 (GRCm39) |
V30I |
probably benign |
Het |
| Slc38a8 |
A |
T |
8: 120,209,423 (GRCm39) |
|
probably null |
Het |
| Smarcd1 |
A |
G |
15: 99,605,862 (GRCm39) |
S378G |
possibly damaging |
Het |
| Stx1b |
T |
C |
7: 127,407,093 (GRCm39) |
I55V |
probably damaging |
Het |
| Sult2a8 |
A |
G |
7: 14,159,457 (GRCm39) |
V54A |
probably damaging |
Het |
| Tacc2 |
T |
C |
7: 130,330,507 (GRCm39) |
S264P |
probably damaging |
Het |
| Tbc1d4 |
A |
T |
14: 101,695,610 (GRCm39) |
Y943N |
probably damaging |
Het |
| Tlr5 |
T |
C |
1: 182,801,038 (GRCm39) |
I114T |
probably benign |
Het |
| Tmco6 |
T |
C |
18: 36,868,555 (GRCm39) |
|
probably null |
Het |
| Treh |
T |
C |
9: 44,593,945 (GRCm39) |
L144P |
probably damaging |
Het |
| Trmt2a |
T |
A |
16: 18,067,418 (GRCm39) |
C30* |
probably null |
Het |
| Ttbk2 |
A |
T |
2: 120,603,758 (GRCm39) |
F258L |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,785,380 (GRCm39) |
D665G |
probably damaging |
Het |
| Unc93b1 |
T |
C |
19: 3,992,023 (GRCm39) |
|
probably null |
Het |
| Uroc1 |
T |
C |
6: 90,322,376 (GRCm39) |
L300P |
probably damaging |
Het |
| Vps35l |
T |
C |
7: 118,379,491 (GRCm39) |
I426T |
possibly damaging |
Het |
| Xbp1 |
A |
G |
11: 5,471,125 (GRCm39) |
E44G |
probably damaging |
Het |
| Zfp451 |
A |
T |
1: 33,816,942 (GRCm39) |
V119D |
probably damaging |
Het |
| Zfp457 |
T |
A |
13: 67,441,342 (GRCm39) |
H315L |
probably damaging |
Het |
| Zfp518a |
T |
A |
19: 40,904,295 (GRCm39) |
V1408D |
possibly damaging |
Het |
| Zfp52 |
T |
G |
17: 21,780,665 (GRCm39) |
L171R |
probably benign |
Het |
| Zfp712 |
C |
T |
13: 67,188,676 (GRCm39) |
C617Y |
probably damaging |
Het |
| Zfp770 |
T |
C |
2: 114,027,868 (GRCm39) |
N67S |
probably benign |
Het |
|
| Other mutations in Caskin1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00402:Caskin1
|
APN |
17 |
24,722,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00846:Caskin1
|
APN |
17 |
24,718,323 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01120:Caskin1
|
APN |
17 |
24,724,343 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL01543:Caskin1
|
APN |
17 |
24,723,522 (GRCm39) |
missense |
probably benign |
|
|
IGL01622:Caskin1
|
APN |
17 |
24,722,914 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01623:Caskin1
|
APN |
17 |
24,722,914 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02120:Caskin1
|
APN |
17 |
24,719,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02816:Caskin1
|
APN |
17 |
24,721,144 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02898:Caskin1
|
APN |
17 |
24,721,383 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03353:Caskin1
|
APN |
17 |
24,718,331 (GRCm39) |
splice site |
probably benign |
|
|
PIT4151001:Caskin1
|
UTSW |
17 |
24,721,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4453001:Caskin1
|
UTSW |
17 |
24,718,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0057:Caskin1
|
UTSW |
17 |
24,723,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0057:Caskin1
|
UTSW |
17 |
24,723,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0190:Caskin1
|
UTSW |
17 |
24,723,596 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0443:Caskin1
|
UTSW |
17 |
24,724,374 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0885:Caskin1
|
UTSW |
17 |
24,724,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1035:Caskin1
|
UTSW |
17 |
24,724,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1253:Caskin1
|
UTSW |
17 |
24,724,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1497:Caskin1
|
UTSW |
17 |
24,723,515 (GRCm39) |
nonsense |
probably null |
|
|
R1589:Caskin1
|
UTSW |
17 |
24,724,452 (GRCm39) |
splice site |
probably null |
|
|
R1651:Caskin1
|
UTSW |
17 |
24,721,186 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1944:Caskin1
|
UTSW |
17 |
24,719,745 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1969:Caskin1
|
UTSW |
17 |
24,725,824 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2057:Caskin1
|
UTSW |
17 |
24,715,433 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2127:Caskin1
|
UTSW |
17 |
24,715,970 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2158:Caskin1
|
UTSW |
17 |
24,724,128 (GRCm39) |
missense |
probably benign |
|
|
R2402:Caskin1
|
UTSW |
17 |
24,722,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2895:Caskin1
|
UTSW |
17 |
24,708,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3423:Caskin1
|
UTSW |
17 |
24,718,539 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3800:Caskin1
|
UTSW |
17 |
24,720,246 (GRCm39) |
missense |
probably benign |
|
|
R4108:Caskin1
|
UTSW |
17 |
24,721,121 (GRCm39) |
missense |
probably benign |
|
|
R4419:Caskin1
|
UTSW |
17 |
24,723,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4510:Caskin1
|
UTSW |
17 |
24,725,602 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4511:Caskin1
|
UTSW |
17 |
24,725,602 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4552:Caskin1
|
UTSW |
17 |
24,725,602 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4638:Caskin1
|
UTSW |
17 |
24,725,602 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4642:Caskin1
|
UTSW |
17 |
24,725,602 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4644:Caskin1
|
UTSW |
17 |
24,725,602 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4824:Caskin1
|
UTSW |
17 |
24,720,103 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4882:Caskin1
|
UTSW |
17 |
24,723,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4966:Caskin1
|
UTSW |
17 |
24,726,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5809:Caskin1
|
UTSW |
17 |
24,723,521 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5841:Caskin1
|
UTSW |
17 |
24,715,183 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5877:Caskin1
|
UTSW |
17 |
24,724,239 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5960:Caskin1
|
UTSW |
17 |
24,717,869 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5994:Caskin1
|
UTSW |
17 |
24,715,935 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6022:Caskin1
|
UTSW |
17 |
24,715,709 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6209:Caskin1
|
UTSW |
17 |
24,726,095 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6228:Caskin1
|
UTSW |
17 |
24,726,154 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6287:Caskin1
|
UTSW |
17 |
24,715,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6497:Caskin1
|
UTSW |
17 |
24,723,522 (GRCm39) |
missense |
probably benign |
|
|
R6873:Caskin1
|
UTSW |
17 |
24,723,153 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7079:Caskin1
|
UTSW |
17 |
24,717,858 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7156:Caskin1
|
UTSW |
17 |
24,719,657 (GRCm39) |
splice site |
probably null |
|
|
R7385:Caskin1
|
UTSW |
17 |
24,722,898 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7953:Caskin1
|
UTSW |
17 |
24,723,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7993:Caskin1
|
UTSW |
17 |
24,718,279 (GRCm39) |
nonsense |
probably null |
|
|
R8410:Caskin1
|
UTSW |
17 |
24,721,123 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8511:Caskin1
|
UTSW |
17 |
24,724,910 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8749:Caskin1
|
UTSW |
17 |
24,723,774 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8881:Caskin1
|
UTSW |
17 |
24,718,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8979:Caskin1
|
UTSW |
17 |
24,717,899 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R9005:Caskin1
|
UTSW |
17 |
24,718,111 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9341:Caskin1
|
UTSW |
17 |
24,723,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9343:Caskin1
|
UTSW |
17 |
24,723,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0022:Caskin1
|
UTSW |
17 |
24,724,140 (GRCm39) |
missense |
probably benign |
0.34 |
|
X0063:Caskin1
|
UTSW |
17 |
24,726,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Caskin1
|
UTSW |
17 |
24,724,012 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Caskin1
|
UTSW |
17 |
24,715,661 (GRCm39) |
missense |
probably damaging |
0.97 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGCCAGTGGACTGCTATG -3'
(R):5'- AGTTGTTGCACAGGGAGCAG -3'
Sequencing Primer
(F):5'- CCAGTGGACTGCTATGGGTAG -3'
(R):5'- ATCTGCTCAGAGCCCTTGGAG -3'
|
| Posted On |
2016-04-27 |
Incidental Mutation