Incidental Mutation 'IGL03378:Svs5'
ID420573
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Svs5
Ensembl Gene ENSMUSG00000017004
Gene Nameseminal vesicle secretory protein 5
Synonymsseminal vesicle protein F, SVS V, Svp5, Svp-1, Svp1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.073) question?
Stock #IGL03378
Quality Score
Status
Chromosome2
Chromosomal Location164332740-164334396 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to A at 164333340 bp
ZygosityHeterozygous
Amino Acid Change Histidine to Glutamine at position 37 (H37Q)
Ref Sequence ENSEMBL: ENSMUSP00000017148 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000017148]
Predicted Effect probably benign
Transcript: ENSMUST00000017148
AA Change: H37Q

PolyPhen 2 Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
SMART Domains Protein: ENSMUSP00000017148
Gene: ENSMUSG00000017004
AA Change: H37Q

DomainStartEndE-ValueType
signal peptide 1 21 N/A INTRINSIC
low complexity region 45 51 N/A INTRINSIC
low complexity region 72 92 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000149370
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
9430069I07Rik T A 15: 34,355,632 I261N probably benign Het
Bace1 T A 9: 45,858,901 probably null Het
Caprin2 G T 6: 148,877,854 Q152K probably benign Het
Cdh16 C T 8: 104,619,285 D285N probably benign Het
Cnnm2 G A 19: 46,878,034 A874T possibly damaging Het
Dhx38 A T 8: 109,559,090 probably null Het
Dnhd1 A C 7: 105,713,733 E3834A possibly damaging Het
Erc2 A C 14: 28,011,723 S585R probably damaging Het
Gli3 A G 13: 15,644,420 E269G probably damaging Het
Gpr161 T C 1: 165,310,508 L204P probably damaging Het
Hp A G 8: 109,575,707 V203A probably damaging Het
Krtap6-5 A T 16: 89,047,789 C19S unknown Het
Lce1i A T 3: 92,777,726 S48T unknown Het
Lrp2 A T 2: 69,431,152 S4482T probably damaging Het
Mpdz A T 4: 81,419,048 probably benign Het
Olfr1049 T A 2: 86,255,019 I225L possibly damaging Het
Olfr1186 T A 2: 88,526,154 Y190* probably null Het
Olfr357 T C 2: 36,996,903 F31S probably damaging Het
Papola G T 12: 105,809,433 probably null Het
Prss23 T C 7: 89,510,144 D239G probably damaging Het
Setd2 A G 9: 110,553,152 T83A unknown Het
Sh3pxd2b T G 11: 32,381,443 L56V probably damaging Het
Ski A G 4: 155,160,872 S300P probably benign Het
Srebf2 T C 15: 82,169,788 S17P probably damaging Het
Tbx21 A G 11: 97,114,741 S133P probably benign Het
Tgfbr3 G T 5: 107,109,702 S830R probably damaging Het
Thsd1 A T 8: 22,243,778 K280N probably benign Het
Tnfrsf13c T A 15: 82,224,312 M1L probably benign Het
Ttll7 T C 3: 146,909,653 F291L probably benign Het
Ttn A G 2: 76,769,563 V10762A probably damaging Het
Other mutations in Svs5
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0781:Svs5 UTSW 2 164333587 missense probably benign 0.16
R1110:Svs5 UTSW 2 164333587 missense probably benign 0.16
R3103:Svs5 UTSW 2 164333393 missense probably benign 0.00
R7338:Svs5 UTSW 2 164332808 missense possibly damaging 0.96
R8019:Svs5 UTSW 2 164333421 missense possibly damaging 0.86
Z1176:Svs5 UTSW 2 164332791 missense possibly damaging 0.73
Posted On2016-08-02