Incidental Mutation 'R9127:Prrc2b'
| ID |
693300 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prrc2b
|
| Ensembl Gene |
ENSMUSG00000039262 |
| Gene Name |
proline-rich coiled-coil 2B |
| Synonyms |
5830434P21Rik, Bat2l |
| MMRRC Submission |
068926-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9127 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
32041094-32124549 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 32103764 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Serine
at position 1081
(R1081S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000064892
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036691]
[ENSMUST00000069817]
|
| AlphaFold |
Q7TPM1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000036691
|
| SMART Domains |
Protein: ENSMUSP00000035734
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
194 |
2.7e-85 |
PFAM |
|
low complexity region
|
359 |
374 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
394 |
N/A |
INTRINSIC |
|
low complexity region
|
413 |
424 |
N/A |
INTRINSIC |
|
coiled coil region
|
494 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
621 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
656 |
N/A |
INTRINSIC |
|
low complexity region
|
885 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
992 |
1007 |
N/A |
INTRINSIC |
|
low complexity region
|
1112 |
1126 |
N/A |
INTRINSIC |
|
low complexity region
|
1218 |
1233 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1275 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1421 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1437 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000069817
AA Change: R1081S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000064892
Gene: ENSMUSG00000039262
AA Change: R1081S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
191 |
3.1e-65 |
PFAM |
|
low complexity region
|
359 |
374 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
394 |
N/A |
INTRINSIC |
|
low complexity region
|
413 |
424 |
N/A |
INTRINSIC |
|
coiled coil region
|
494 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
621 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
656 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
977 |
N/A |
INTRINSIC |
|
low complexity region
|
1004 |
1018 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1094 |
N/A |
INTRINSIC |
|
low complexity region
|
1307 |
1325 |
N/A |
INTRINSIC |
|
low complexity region
|
1388 |
1401 |
N/A |
INTRINSIC |
|
low complexity region
|
1413 |
1426 |
N/A |
INTRINSIC |
|
low complexity region
|
1572 |
1587 |
N/A |
INTRINSIC |
|
low complexity region
|
1678 |
1693 |
N/A |
INTRINSIC |
|
low complexity region
|
1798 |
1812 |
N/A |
INTRINSIC |
|
low complexity region
|
1904 |
1919 |
N/A |
INTRINSIC |
|
low complexity region
|
1943 |
1961 |
N/A |
INTRINSIC |
|
low complexity region
|
2088 |
2107 |
N/A |
INTRINSIC |
|
low complexity region
|
2111 |
2123 |
N/A |
INTRINSIC |
|
low complexity region
|
2161 |
2174 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128936
|
| SMART Domains |
Protein: ENSMUSP00000121664
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
53 |
68 |
N/A |
INTRINSIC |
|
low complexity region
|
159 |
174 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132459
|
| SMART Domains |
Protein: ENSMUSP00000116429
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
119 |
9.8e-24 |
PFAM |
|
low complexity region
|
287 |
302 |
N/A |
INTRINSIC |
|
low complexity region
|
316 |
322 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
352 |
N/A |
INTRINSIC |
|
coiled coil region
|
421 |
471 |
N/A |
INTRINSIC |
|
low complexity region
|
528 |
549 |
N/A |
INTRINSIC |
|
low complexity region
|
566 |
584 |
N/A |
INTRINSIC |
|
low complexity region
|
813 |
828 |
N/A |
INTRINSIC |
|
low complexity region
|
920 |
935 |
N/A |
INTRINSIC |
|
low complexity region
|
1040 |
1054 |
N/A |
INTRINSIC |
|
low complexity region
|
1146 |
1161 |
N/A |
INTRINSIC |
|
low complexity region
|
1185 |
1203 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1349 |
N/A |
INTRINSIC |
|
low complexity region
|
1353 |
1365 |
N/A |
INTRINSIC |
|
low complexity region
|
1403 |
1416 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156313
|
| SMART Domains |
Protein: ENSMUSP00000114994
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
125 |
140 |
N/A |
INTRINSIC |
|
low complexity region
|
231 |
246 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
100% (82/82) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
T |
G |
11: 9,242,080 (GRCm39) |
D1314E |
probably benign |
Het |
| Abcb1a |
A |
T |
5: 8,724,707 (GRCm39) |
R47W |
probably benign |
Het |
| Abcc6 |
T |
C |
7: 45,629,184 (GRCm39) |
N1354S |
probably damaging |
Het |
| Abracl |
T |
C |
10: 17,887,444 (GRCm39) |
Y61C |
probably damaging |
Het |
| Adamtsl1 |
A |
G |
4: 86,208,027 (GRCm39) |
T633A |
probably benign |
Het |
| Agap3 |
G |
A |
5: 24,681,439 (GRCm39) |
|
probably benign |
Het |
| Ago4 |
A |
T |
4: 126,400,904 (GRCm39) |
M647K |
probably damaging |
Het |
| Akap7 |
G |
T |
10: 25,155,676 (GRCm39) |
S72R |
unknown |
Het |
| Arhgef12 |
A |
G |
9: 42,885,870 (GRCm39) |
L1251S |
possibly damaging |
Het |
| Astn2 |
A |
T |
4: 66,322,164 (GRCm39) |
V145E |
unknown |
Het |
| Atxn2l |
A |
T |
7: 126,097,393 (GRCm39) |
S304R |
probably damaging |
Het |
| Cd226 |
A |
T |
18: 89,287,155 (GRCm39) |
I318F |
probably damaging |
Het |
| Cep250 |
C |
T |
2: 155,812,042 (GRCm39) |
A446V |
unknown |
Het |
| Cfap65 |
A |
T |
1: 74,958,510 (GRCm39) |
|
probably benign |
Het |
| Cfap96 |
T |
G |
8: 46,415,403 (GRCm39) |
D201A |
probably benign |
Het |
| Chtf8 |
A |
G |
8: 107,613,640 (GRCm39) |
V18A |
probably benign |
Het |
| Cit |
G |
T |
5: 116,074,896 (GRCm39) |
E683* |
probably null |
Het |
| Ckmt2 |
T |
C |
13: 92,007,337 (GRCm39) |
R286G |
probably damaging |
Het |
| Clec4a2 |
T |
A |
6: 123,116,218 (GRCm39) |
W128R |
probably damaging |
Het |
| Clec4n |
T |
G |
6: 123,212,447 (GRCm39) |
S88A |
probably damaging |
Het |
| Cndp2 |
G |
A |
18: 84,699,121 (GRCm39) |
A48V |
probably benign |
Het |
| Csmd1 |
T |
C |
8: 16,273,286 (GRCm39) |
T849A |
probably benign |
Het |
| Cts3 |
A |
T |
13: 61,715,235 (GRCm39) |
Y199* |
probably null |
Het |
| Dag1 |
A |
T |
9: 108,085,734 (GRCm39) |
L469* |
probably null |
Het |
| Dclre1c |
T |
C |
2: 3,439,125 (GRCm39) |
V225A |
|
Het |
| Dedd |
A |
G |
1: 171,166,409 (GRCm39) |
D115G |
probably damaging |
Het |
| Efcab3 |
T |
A |
11: 104,741,407 (GRCm39) |
V2166D |
probably benign |
Het |
| Eif2ak3 |
T |
A |
6: 70,860,704 (GRCm39) |
W427R |
probably damaging |
Het |
| Fbln2 |
T |
A |
6: 91,210,473 (GRCm39) |
V139D |
probably damaging |
Het |
| Fbn1 |
A |
T |
2: 125,223,985 (GRCm39) |
M588K |
possibly damaging |
Het |
| Gm17019 |
A |
T |
5: 15,081,113 (GRCm39) |
Y109* |
probably null |
Het |
| Gm32742 |
T |
A |
9: 51,056,015 (GRCm39) |
N1255Y |
probably damaging |
Het |
| Gm5431 |
T |
A |
11: 48,779,600 (GRCm39) |
K441* |
probably null |
Het |
| Golga2 |
A |
G |
2: 32,196,079 (GRCm39) |
D898G |
|
Het |
| Gramd4 |
G |
A |
15: 85,975,525 (GRCm39) |
R39H |
probably benign |
Het |
| Gucy1a2 |
A |
G |
9: 3,634,553 (GRCm39) |
N199S |
probably damaging |
Het |
| Heyl |
G |
A |
4: 123,139,885 (GRCm39) |
R148H |
probably damaging |
Het |
| Ifi208 |
A |
T |
1: 173,523,400 (GRCm39) |
M557L |
probably benign |
Het |
| Igf2r |
A |
G |
17: 12,958,238 (GRCm39) |
V145A |
probably damaging |
Het |
| Ighv1-4 |
A |
T |
12: 114,450,879 (GRCm39) |
Y76* |
probably null |
Het |
| Ikzf4 |
T |
C |
10: 128,468,487 (GRCm39) |
D664G |
unknown |
Het |
| Il1a |
T |
A |
2: 129,146,715 (GRCm39) |
Y126F |
possibly damaging |
Het |
| Lmf2 |
C |
A |
15: 89,239,771 (GRCm39) |
|
probably benign |
Het |
| Lyst |
T |
C |
13: 13,808,827 (GRCm39) |
S166P |
probably damaging |
Het |
| Mgat5 |
A |
C |
1: 127,294,197 (GRCm39) |
T180P |
probably benign |
Het |
| Mical2 |
A |
C |
7: 111,870,589 (GRCm39) |
K26T |
possibly damaging |
Het |
| Mov10 |
G |
T |
3: 104,711,659 (GRCm39) |
Y209* |
probably null |
Het |
| Nol8 |
T |
C |
13: 49,815,475 (GRCm39) |
Y528H |
probably benign |
Het |
| Numa1 |
T |
A |
7: 101,641,869 (GRCm39) |
S106T |
possibly damaging |
Het |
| Or1e1d-ps1 |
A |
T |
11: 73,819,167 (GRCm39) |
E39V |
probably damaging |
Het |
| Or4c124 |
G |
A |
2: 89,156,474 (GRCm39) |
Q17* |
probably null |
Het |
| Or5b107 |
A |
G |
19: 13,142,396 (GRCm39) |
N6S |
probably damaging |
Het |
| Or7g27 |
A |
G |
9: 19,250,026 (GRCm39) |
H90R |
probably benign |
Het |
| Pcdhb14 |
A |
G |
18: 37,582,091 (GRCm39) |
N399S |
probably damaging |
Het |
| Plcl2 |
T |
A |
17: 50,918,032 (GRCm39) |
S944T |
probably benign |
Het |
| Pml |
A |
T |
9: 58,127,660 (GRCm39) |
I695N |
probably benign |
Het |
| Ppard |
G |
T |
17: 28,505,349 (GRCm39) |
R12L |
unknown |
Het |
| Ppip5k1 |
C |
T |
2: 121,158,125 (GRCm39) |
|
probably null |
Het |
| Ppp1r3g |
T |
C |
13: 36,152,621 (GRCm39) |
S14P |
probably benign |
Het |
| Pramel55 |
A |
G |
5: 95,951,623 (GRCm39) |
Y470C |
probably damaging |
Het |
| Rasgrp2 |
A |
T |
19: 6,454,438 (GRCm39) |
E160D |
possibly damaging |
Het |
| Rb1cc1 |
G |
A |
1: 6,333,073 (GRCm39) |
V1331I |
probably damaging |
Het |
| Rnd3 |
A |
T |
2: 51,022,413 (GRCm39) |
S210T |
probably benign |
Het |
| Scaf11 |
T |
C |
15: 96,312,764 (GRCm39) |
T1426A |
probably benign |
Het |
| Sin3b |
C |
T |
8: 73,460,034 (GRCm39) |
T207I |
possibly damaging |
Het |
| Slc26a7 |
A |
T |
4: 14,593,873 (GRCm39) |
Y81N |
probably damaging |
Het |
| Slc28a3 |
C |
T |
13: 58,724,581 (GRCm39) |
M224I |
probably benign |
Het |
| Slc30a1 |
T |
C |
1: 191,639,342 (GRCm39) |
I75T |
probably damaging |
Het |
| Slc6a21 |
T |
A |
7: 44,929,674 (GRCm39) |
|
probably benign |
Het |
| Slco2a1 |
T |
A |
9: 102,945,243 (GRCm39) |
L206Q |
probably damaging |
Het |
| Spata31d1e |
A |
G |
13: 59,890,828 (GRCm39) |
S331P |
probably benign |
Het |
| Sptbn1 |
A |
G |
11: 30,104,356 (GRCm39) |
V116A |
probably damaging |
Het |
| Syngap1 |
G |
A |
17: 27,181,095 (GRCm39) |
D1008N |
probably damaging |
Het |
| Syt11 |
T |
C |
3: 88,669,643 (GRCm39) |
D83G |
probably benign |
Het |
| Syt14 |
G |
A |
1: 192,584,131 (GRCm39) |
T428I |
probably damaging |
Het |
| Taf15 |
T |
A |
11: 83,395,085 (GRCm39) |
Y338* |
probably null |
Het |
| Tfap4 |
A |
T |
16: 4,365,183 (GRCm39) |
M253K |
possibly damaging |
Het |
| Tnr |
T |
C |
1: 159,713,680 (GRCm39) |
S703P |
possibly damaging |
Het |
| Trrap |
G |
A |
5: 144,767,830 (GRCm39) |
D2577N |
probably benign |
Het |
| Uqcc6 |
A |
T |
10: 82,458,588 (GRCm39) |
M21K |
probably benign |
Het |
| Wdr20 |
C |
T |
12: 110,759,597 (GRCm39) |
S161L |
possibly damaging |
Het |
| Zfp503 |
C |
A |
14: 22,037,418 (GRCm39) |
V62L |
probably benign |
Het |
|
| Other mutations in Prrc2b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00156:Prrc2b
|
APN |
2 |
32,098,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00846:Prrc2b
|
APN |
2 |
32,089,109 (GRCm39) |
splice site |
probably benign |
|
|
IGL00977:Prrc2b
|
APN |
2 |
32,103,822 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01372:Prrc2b
|
APN |
2 |
32,113,942 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01993:Prrc2b
|
APN |
2 |
32,114,057 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02097:Prrc2b
|
APN |
2 |
32,081,513 (GRCm39) |
splice site |
probably benign |
|
|
IGL02165:Prrc2b
|
APN |
2 |
32,104,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02184:Prrc2b
|
APN |
2 |
32,111,467 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02238:Prrc2b
|
APN |
2 |
32,103,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02338:Prrc2b
|
APN |
2 |
32,104,047 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02399:Prrc2b
|
APN |
2 |
32,116,973 (GRCm39) |
nonsense |
probably null |
|
|
IGL02597:Prrc2b
|
APN |
2 |
32,109,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02729:Prrc2b
|
APN |
2 |
32,098,770 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02743:Prrc2b
|
APN |
2 |
32,084,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02815:Prrc2b
|
APN |
2 |
32,094,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03159:Prrc2b
|
APN |
2 |
32,084,498 (GRCm39) |
missense |
probably damaging |
0.98 |
|
BB002:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB012:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4304:Prrc2b
|
UTSW |
2 |
32,111,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0082:Prrc2b
|
UTSW |
2 |
32,102,310 (GRCm39) |
splice site |
probably benign |
|
|
R0105:Prrc2b
|
UTSW |
2 |
32,103,323 (GRCm39) |
nonsense |
probably null |
|
|
R0276:Prrc2b
|
UTSW |
2 |
32,109,666 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0325:Prrc2b
|
UTSW |
2 |
32,089,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0436:Prrc2b
|
UTSW |
2 |
32,120,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0595:Prrc2b
|
UTSW |
2 |
32,073,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0607:Prrc2b
|
UTSW |
2 |
32,103,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0650:Prrc2b
|
UTSW |
2 |
32,119,267 (GRCm39) |
splice site |
probably benign |
|
|
R1282:Prrc2b
|
UTSW |
2 |
32,113,456 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1421:Prrc2b
|
UTSW |
2 |
32,090,990 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R1452:Prrc2b
|
UTSW |
2 |
32,084,997 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1535:Prrc2b
|
UTSW |
2 |
32,094,301 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1709:Prrc2b
|
UTSW |
2 |
32,084,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1710:Prrc2b
|
UTSW |
2 |
32,102,234 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2094:Prrc2b
|
UTSW |
2 |
32,072,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2202:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2203:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2204:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2428:Prrc2b
|
UTSW |
2 |
32,106,067 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2435:Prrc2b
|
UTSW |
2 |
32,109,741 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3439:Prrc2b
|
UTSW |
2 |
32,096,359 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4175:Prrc2b
|
UTSW |
2 |
32,108,820 (GRCm39) |
intron |
probably benign |
|
|
R4710:Prrc2b
|
UTSW |
2 |
32,083,869 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4728:Prrc2b
|
UTSW |
2 |
32,120,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4791:Prrc2b
|
UTSW |
2 |
32,107,351 (GRCm39) |
splice site |
probably null |
|
|
R4876:Prrc2b
|
UTSW |
2 |
32,104,212 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4908:Prrc2b
|
UTSW |
2 |
32,116,330 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4997:Prrc2b
|
UTSW |
2 |
32,112,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5240:Prrc2b
|
UTSW |
2 |
32,096,408 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5276:Prrc2b
|
UTSW |
2 |
32,104,734 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5455:Prrc2b
|
UTSW |
2 |
32,111,355 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5821:Prrc2b
|
UTSW |
2 |
32,102,144 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5835:Prrc2b
|
UTSW |
2 |
32,096,485 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5958:Prrc2b
|
UTSW |
2 |
32,102,092 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6052:Prrc2b
|
UTSW |
2 |
32,102,297 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6218:Prrc2b
|
UTSW |
2 |
32,098,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6428:Prrc2b
|
UTSW |
2 |
32,116,508 (GRCm39) |
splice site |
probably null |
|
|
R6505:Prrc2b
|
UTSW |
2 |
32,112,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6812:Prrc2b
|
UTSW |
2 |
32,103,153 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6826:Prrc2b
|
UTSW |
2 |
32,112,300 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6827:Prrc2b
|
UTSW |
2 |
32,090,963 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7021:Prrc2b
|
UTSW |
2 |
32,111,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7078:Prrc2b
|
UTSW |
2 |
32,103,531 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7081:Prrc2b
|
UTSW |
2 |
32,103,075 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7101:Prrc2b
|
UTSW |
2 |
32,117,005 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7215:Prrc2b
|
UTSW |
2 |
32,119,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7228:Prrc2b
|
UTSW |
2 |
32,104,318 (GRCm39) |
nonsense |
probably null |
|
|
R7566:Prrc2b
|
UTSW |
2 |
32,084,402 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7719:Prrc2b
|
UTSW |
2 |
32,107,280 (GRCm39) |
nonsense |
probably null |
|
|
R7925:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7999:Prrc2b
|
UTSW |
2 |
32,084,426 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8099:Prrc2b
|
UTSW |
2 |
32,098,686 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8154:Prrc2b
|
UTSW |
2 |
32,108,689 (GRCm39) |
missense |
probably benign |
0.42 |
|
R8252:Prrc2b
|
UTSW |
2 |
32,109,392 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8379:Prrc2b
|
UTSW |
2 |
32,104,666 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8485:Prrc2b
|
UTSW |
2 |
32,102,105 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8845:Prrc2b
|
UTSW |
2 |
32,106,162 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Prrc2b
|
UTSW |
2 |
32,102,105 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8919:Prrc2b
|
UTSW |
2 |
32,104,953 (GRCm39) |
missense |
probably benign |
|
|
R8982:Prrc2b
|
UTSW |
2 |
32,102,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9065:Prrc2b
|
UTSW |
2 |
32,109,304 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9217:Prrc2b
|
UTSW |
2 |
32,103,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9338:Prrc2b
|
UTSW |
2 |
32,098,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9344:Prrc2b
|
UTSW |
2 |
32,103,600 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9386:Prrc2b
|
UTSW |
2 |
32,104,125 (GRCm39) |
missense |
probably benign |
|
|
R9601:Prrc2b
|
UTSW |
2 |
32,090,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9607:Prrc2b
|
UTSW |
2 |
32,098,794 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9670:Prrc2b
|
UTSW |
2 |
32,103,199 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9706:Prrc2b
|
UTSW |
2 |
32,107,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Prrc2b
|
UTSW |
2 |
32,106,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Prrc2b
|
UTSW |
2 |
32,104,441 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1177:Prrc2b
|
UTSW |
2 |
32,116,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTAGAGAGGAGAGCTCACAGC -3'
(R):5'- GGGCAGCTCTTCATACTCAG -3'
Sequencing Primer
(F):5'- TGGAGGACAAGGCTGCCTC -3'
(R):5'- TGAGTCTCGCTGGCAATGC -3'
|
| Posted On |
2022-01-20 |
Incidental Mutation