Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01510:Tcerg1l'

89199

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tcerg1l

Ensembl Gene

ENSMUSG00000091002

Gene Name

transcription elongation regulator 1-like

Synonyms

5730476P14Rik

Accession Numbers

Is this an essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01510

Quality Score

Status

Chromosome

Chromosomal Location

138208974-138397730 bp(-) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 138394305 bp

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000124476 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000160436]

Predicted Effect

probably benign
Transcript: ENSMUST00000160436

SMART Domains

Protein: ENSMUSP00000124476
Gene: ENSMUSG00000091002

Domain	Start	End	E-Value	Type
low complexity region	6	44	N/A	INTRINSIC
low complexity region	52	97	N/A	INTRINSIC
WW	146	178	2.11e1	SMART
low complexity region	235	249	N/A	INTRINSIC
WW	344	376	3.29e-4	SMART
low complexity region	402	415	N/A	INTRINSIC
FF	454	507	4.57e-12	SMART
FF	520	574	1.53e-4	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000162222

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 44 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca1	T	C	4: 53,143,979	Q6R	probably damaging	Het
Adam5	A	T	8: 24,804,465	C373S	probably damaging	Het
Adgre4	T	C	17: 55,818,760		probably null	Het
Akap10	A	T	11: 61,878,020	M614K	possibly damaging	Het
Amigo2	T	C	15: 97,245,081	T487A	probably benign	Het
Asap1	T	C	15: 64,158,928	D300G	probably damaging	Het
Atp4a	C	A	7: 30,720,791	L788M	probably benign	Het
Bcl3	T	A	7: 19,809,614	H309L	probably damaging	Het
Cblc	T	C	7: 19,785,275	N376S	probably benign	Het
Cd200r2	A	T	16: 44,909,311	I110L	probably benign	Het
Ceacam3	T	C	7: 17,159,842	M426T	probably benign	Het
Cep295	G	A	9: 15,354,626	R29*	probably null	Het
Ces1a	G	T	8: 93,045,098	P24T	probably damaging	Het
Ctps	G	T	4: 120,558,844	T194K	probably damaging	Het
Cul3	A	G	1: 80,282,679	S318P	probably damaging	Het
Fasl	A	T	1: 161,781,953	S155T	possibly damaging	Het
Gldc	C	T	19: 30,113,721		probably null	Het
Gpr21	T	A	2: 37,518,421	C326*	probably null	Het
Gtf2a1	A	G	12: 91,567,833	S216P	probably benign	Het
Hoxb5	A	T	11: 96,303,992	S127C	possibly damaging	Het
Htt	A	T	5: 34,907,512	Q3023L	probably damaging	Het
Kalrn	T	A	16: 34,235,330	H855L	possibly damaging	Het
Lars	T	C	18: 42,242,109	I289V	probably benign	Het
Lrig3	C	A	10: 126,008,698	T677K	probably damaging	Het
Mapk7	A	T	11: 61,491,160	W309R	probably damaging	Het
Mmp12	A	G	9: 7,358,307	T468A	possibly damaging	Het
Muc5b	A	T	7: 141,859,061	N1915Y	unknown	Het
Naprt	A	G	15: 75,890,988		probably benign	Het
Nfatc1	T	C	18: 80,698,188	Y199C	probably damaging	Het
Olfr857	A	T	9: 19,713,279	I151F	probably benign	Het
Olfr919	T	C	9: 38,697,905	I158V	probably benign	Het
Phip	T	A	9: 82,913,871	I566F	probably benign	Het
Pnpla3	T	A	15: 84,171,072		probably benign	Het
Ptpn13	C	T	5: 103,562,300	T1567I	probably damaging	Het
Ptpn20	A	G	14: 33,638,386		probably null	Het
Ptprq	G	T	10: 107,712,048	T163K	probably damaging	Het
Slc8a1	A	G	17: 81,648,365	C415R	probably damaging	Het
Slco4c1	A	G	1: 96,867,953	S127P	probably damaging	Het
Thbd	C	T	2: 148,406,974	V325M	probably damaging	Het
Trim37	G	A	11: 87,177,860	R344H	probably damaging	Het
Ttn	T	C	2: 76,872,765		probably benign	Het
Uvrag	G	A	7: 99,004,589	Q65*	probably null	Het
Wrap53	G	A	11: 69,562,740	S342L	possibly damaging	Het
Zbtb11	T	G	16: 55,990,343	V288G	probably damaging	Het

Other mutations in Tcerg1l

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00504:Tcerg1l	APN	7	138209804	missense	probably damaging	0.99
IGL01402:Tcerg1l	APN	7	138259839	missense	probably damaging	0.98
IGL01638:Tcerg1l	APN	7	138280076	missense	probably damaging	1.00
IGL01710:Tcerg1l	APN	7	138395060	missense	possibly damaging	0.81
IGL02547:Tcerg1l	APN	7	138248371	critical splice donor site	probably null
IGL02887:Tcerg1l	APN	7	138229890	missense	probably damaging	1.00
IGL03105:Tcerg1l	APN	7	138248444	splice site	probably benign
IGL03348:Tcerg1l	APN	7	138213371	missense	probably damaging	0.97
R0378:Tcerg1l	UTSW	7	138276655	missense	probably benign	0.01
R1474:Tcerg1l	UTSW	7	138280075	missense	probably damaging	0.99
R1589:Tcerg1l	UTSW	7	138361767	missense	probably damaging	0.99
R1658:Tcerg1l	UTSW	7	138394180	missense	probably damaging	0.98
R1792:Tcerg1l	UTSW	7	138361866	missense	probably benign	0.07
R1807:Tcerg1l	UTSW	7	138395097	missense	probably benign	0.34
R2920:Tcerg1l	UTSW	7	138248379	missense	probably damaging	0.99
R3148:Tcerg1l	UTSW	7	138259867	missense	probably benign
R4106:Tcerg1l	UTSW	7	138259944	missense	probably damaging	0.99
R4180:Tcerg1l	UTSW	7	138276676	critical splice acceptor site	probably null
R4241:Tcerg1l	UTSW	7	138397632	missense	unknown
R4898:Tcerg1l	UTSW	7	138218057	missense	probably damaging	0.99
R5652:Tcerg1l	UTSW	7	138280046	missense	probably damaging	0.97
R6646:Tcerg1l	UTSW	7	138395183	splice site	probably null
R6824:Tcerg1l	UTSW	7	138394115	critical splice donor site	probably null
R7414:Tcerg1l	UTSW	7	138218057	missense	probably damaging	0.97
R7490:Tcerg1l	UTSW	7	138259828	missense	probably damaging	1.00
R8810:Tcerg1l	UTSW	7	138209797	missense	not run

Posted On

2013-12-03