Incidental Mutation 'R2137:Rcbtb2'
| ID |
235910 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rcbtb2
|
| Ensembl Gene |
ENSMUSG00000022106 |
| Gene Name |
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| Synonyms |
Rc/btb2, 2810420M18Rik, 2610028E02Rik, Chc1l |
| MMRRC Submission |
040140-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.274)
|
| Stock # |
R2137 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
14 |
| Chromosomal Location |
73376185-73421495 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 73399491 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Serine
at position 52
(G52S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000130732
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000022702]
[ENSMUST00000110952]
[ENSMUST00000163339]
[ENSMUST00000163533]
[ENSMUST00000163797]
[ENSMUST00000164298]
[ENSMUST00000164822]
[ENSMUST00000167401]
[ENSMUST00000165567]
[ENSMUST00000171070]
[ENSMUST00000165429]
[ENSMUST00000170370]
[ENSMUST00000169479]
[ENSMUST00000170368]
[ENSMUST00000171767]
[ENSMUST00000170677]
[ENSMUST00000169513]
[ENSMUST00000167021]
[ENSMUST00000165727]
|
| AlphaFold |
Q99LJ7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000022702
AA Change: G52S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000022702
Gene: ENSMUSG00000022106
AA Change: G52S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
117 |
167 |
1.1e-16 |
PFAM |
|
Pfam:RCC1_2
|
154 |
183 |
7.1e-15 |
PFAM |
|
Pfam:RCC1
|
170 |
220 |
1.7e-14 |
PFAM |
|
Pfam:RCC1
|
223 |
272 |
7.1e-18 |
PFAM |
|
Pfam:RCC1_2
|
259 |
288 |
1.7e-12 |
PFAM |
|
Pfam:RCC1
|
275 |
324 |
8e-16 |
PFAM |
|
BTB
|
394 |
487 |
2.69e-21 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000110952
AA Change: G52S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000106577
Gene: ENSMUSG00000022106
AA Change: G52S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
117 |
167 |
3e-16 |
PFAM |
|
Pfam:RCC1_2
|
154 |
183 |
7.8e-15 |
PFAM |
|
Pfam:RCC1
|
170 |
220 |
1.4e-15 |
PFAM |
|
Pfam:RCC1
|
223 |
272 |
9.4e-18 |
PFAM |
|
Pfam:RCC1_2
|
259 |
288 |
2.6e-11 |
PFAM |
|
Pfam:RCC1
|
275 |
324 |
1.2e-13 |
PFAM |
|
BTB
|
394 |
487 |
2.69e-21 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163339
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000163533
AA Change: G52S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000130828
Gene: ENSMUSG00000022106
AA Change: G52S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
117 |
150 |
4.3e-10 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000163797
AA Change: G38S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000132125
Gene: ENSMUSG00000022106
AA Change: G38S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
136 |
174 |
7.7e-12 |
PFAM |
|
low complexity region
|
199 |
207 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000164298
AA Change: G38S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000126651
Gene: ENSMUSG00000022106
AA Change: G38S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
103 |
153 |
2.9e-17 |
PFAM |
|
Pfam:RCC1_2
|
140 |
169 |
2.2e-15 |
PFAM |
|
Pfam:RCC1
|
156 |
206 |
4.4e-15 |
PFAM |
|
Pfam:RCC1
|
209 |
247 |
1.2e-11 |
PFAM |
|
low complexity region
|
272 |
280 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000164822
AA Change: G52S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000131588
Gene: ENSMUSG00000022106
AA Change: G52S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
117 |
167 |
1.1e-16 |
PFAM |
|
Pfam:RCC1_2
|
154 |
183 |
7.1e-15 |
PFAM |
|
Pfam:RCC1
|
170 |
220 |
1.7e-14 |
PFAM |
|
Pfam:RCC1
|
223 |
272 |
7.1e-18 |
PFAM |
|
Pfam:RCC1_2
|
259 |
288 |
1.7e-12 |
PFAM |
|
Pfam:RCC1
|
275 |
324 |
8e-16 |
PFAM |
|
BTB
|
394 |
487 |
2.69e-21 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000167401
AA Change: G52S
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000165567
AA Change: G52S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000130240
Gene: ENSMUSG00000022106
AA Change: G52S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
117 |
167 |
5.3e-17 |
PFAM |
|
Pfam:RCC1_2
|
154 |
172 |
6.7e-7 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000171070
AA Change: G52S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000165429
AA Change: G28S
PolyPhen 2
Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000127258
Gene: ENSMUSG00000022106
AA Change: G28S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
93 |
143 |
4.4e-17 |
PFAM |
|
Pfam:RCC1_2
|
130 |
157 |
5.2e-13 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000170370
AA Change: G52S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000130732
Gene: ENSMUSG00000022106
AA Change: G52S
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1a12a_
|
45 |
128 |
1e-14 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000169479
AA Change: G52S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000126898
Gene: ENSMUSG00000022106
AA Change: G52S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
117 |
167 |
1.1e-16 |
PFAM |
|
Pfam:RCC1_2
|
154 |
183 |
7.1e-15 |
PFAM |
|
Pfam:RCC1
|
170 |
220 |
1.7e-14 |
PFAM |
|
Pfam:RCC1
|
223 |
272 |
7.1e-18 |
PFAM |
|
Pfam:RCC1_2
|
259 |
288 |
1.7e-12 |
PFAM |
|
Pfam:RCC1
|
275 |
324 |
8e-16 |
PFAM |
|
BTB
|
394 |
487 |
2.69e-21 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000170368
AA Change: G52S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000126276
Gene: ENSMUSG00000022106
AA Change: G52S
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1a12a_
|
45 |
86 |
9e-3 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000171767
AA Change: G52S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000127397
Gene: ENSMUSG00000022106
AA Change: G52S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
117 |
167 |
1.7e-16 |
PFAM |
|
Pfam:RCC1_2
|
154 |
183 |
4.9e-15 |
PFAM |
|
Pfam:RCC1
|
170 |
220 |
8.4e-16 |
PFAM |
|
Pfam:RCC1
|
223 |
272 |
5.5e-18 |
PFAM |
|
Pfam:RCC1_2
|
259 |
288 |
1.7e-11 |
PFAM |
|
Pfam:RCC1
|
275 |
324 |
6.8e-14 |
PFAM |
|
BTB
|
394 |
487 |
2.69e-21 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000170677
AA Change: G28S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000126510
Gene: ENSMUSG00000022106
AA Change: G28S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
93 |
143 |
3.1e-16 |
PFAM |
|
Pfam:RCC1_2
|
130 |
159 |
1.9e-14 |
PFAM |
|
Pfam:RCC1
|
146 |
196 |
4.7e-14 |
PFAM |
|
Pfam:RCC1
|
199 |
248 |
1.9e-17 |
PFAM |
|
Pfam:RCC1_2
|
235 |
264 |
4.4e-12 |
PFAM |
|
Pfam:RCC1
|
251 |
300 |
2.2e-15 |
PFAM |
|
BTB
|
370 |
463 |
2.69e-21 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000169513
AA Change: G28S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000128579
Gene: ENSMUSG00000022106
AA Change: G28S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
93 |
143 |
3.1e-16 |
PFAM |
|
Pfam:RCC1_2
|
130 |
159 |
1.9e-14 |
PFAM |
|
Pfam:RCC1
|
146 |
196 |
4.7e-14 |
PFAM |
|
Pfam:RCC1
|
199 |
248 |
1.9e-17 |
PFAM |
|
Pfam:RCC1_2
|
235 |
264 |
4.4e-12 |
PFAM |
|
Pfam:RCC1
|
251 |
300 |
2.2e-15 |
PFAM |
|
BTB
|
370 |
463 |
2.69e-21 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000171163
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167021
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000165727
|
| SMART Domains |
Protein: ENSMUSP00000128479
Gene: ENSMUSG00000022106
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RCC1
|
11 |
60 |
2.3e-14 |
PFAM |
|
Pfam:RCC1
|
63 |
90 |
6e-9 |
PFAM |
|
| Meta Mutation Damage Score |
0.3483 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.4%
|
| Validation Efficiency |
97% (60/62) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 63 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ankrd24 |
C |
T |
10: 81,482,143 (GRCm39) |
T88I |
probably damaging |
Het |
| Atm |
A |
T |
9: 53,364,675 (GRCm39) |
V49D |
probably damaging |
Het |
| Bub1b |
G |
T |
2: 118,467,199 (GRCm39) |
E841* |
probably null |
Het |
| Cdh20 |
A |
T |
1: 110,027,836 (GRCm39) |
N527I |
probably damaging |
Het |
| Cdh22 |
G |
A |
2: 164,958,314 (GRCm39) |
|
probably benign |
Het |
| Cog1 |
T |
C |
11: 113,550,127 (GRCm39) |
L262P |
probably damaging |
Het |
| Col22a1 |
T |
C |
15: 71,878,797 (GRCm39) |
H120R |
possibly damaging |
Het |
| Col4a2 |
T |
C |
8: 11,483,749 (GRCm39) |
S890P |
probably benign |
Het |
| Cubn |
T |
C |
2: 13,340,978 (GRCm39) |
I2248V |
probably benign |
Het |
| Evpl |
T |
C |
11: 116,112,665 (GRCm39) |
E1675G |
probably damaging |
Het |
| Faiml |
G |
A |
9: 99,114,545 (GRCm39) |
P115S |
probably benign |
Het |
| Fgg |
A |
T |
3: 82,915,745 (GRCm39) |
D62V |
possibly damaging |
Het |
| Gak |
C |
T |
5: 108,754,743 (GRCm39) |
|
probably null |
Het |
| Galntl6 |
C |
T |
8: 58,988,939 (GRCm39) |
|
probably null |
Het |
| Glyr1 |
T |
C |
16: 4,836,346 (GRCm39) |
Y501C |
probably benign |
Het |
| Gm9847 |
G |
T |
12: 14,545,082 (GRCm39) |
|
noncoding transcript |
Het |
| Gria4 |
T |
G |
9: 4,427,026 (GRCm39) |
|
probably benign |
Het |
| Il36b |
A |
G |
2: 24,044,672 (GRCm39) |
N24S |
probably benign |
Het |
| Il6st |
C |
A |
13: 112,639,392 (GRCm39) |
H606N |
possibly damaging |
Het |
| Itprid1 |
A |
G |
6: 55,866,174 (GRCm39) |
Q189R |
probably damaging |
Het |
| Kctd10 |
A |
G |
5: 114,505,389 (GRCm39) |
F202L |
probably damaging |
Het |
| Kif17 |
T |
A |
4: 137,989,978 (GRCm39) |
D55E |
probably damaging |
Het |
| Klf1 |
C |
T |
8: 85,629,775 (GRCm39) |
A200V |
possibly damaging |
Het |
| Klhl32 |
A |
T |
4: 24,629,275 (GRCm39) |
Y497* |
probably null |
Het |
| Kng2 |
G |
T |
16: 22,816,076 (GRCm39) |
|
probably benign |
Het |
| Lats1 |
T |
C |
10: 7,577,611 (GRCm39) |
V245A |
possibly damaging |
Het |
| Mbd3l2 |
A |
T |
9: 18,356,254 (GRCm39) |
D193V |
probably damaging |
Het |
| Ms4a18 |
A |
T |
19: 10,974,695 (GRCm39) |
V332D |
possibly damaging |
Het |
| Mss51 |
T |
C |
14: 20,537,591 (GRCm39) |
I47V |
probably benign |
Het |
| Myoz2 |
G |
A |
3: 122,827,861 (GRCm39) |
T19M |
probably benign |
Het |
| Nampt |
T |
A |
12: 32,880,309 (GRCm39) |
N67K |
probably benign |
Het |
| Ncor2 |
A |
T |
5: 125,107,776 (GRCm39) |
I1607K |
probably damaging |
Het |
| Nudt4 |
T |
C |
10: 95,399,600 (GRCm39) |
Q7R |
probably damaging |
Het |
| Or5b119 |
A |
G |
19: 13,457,173 (GRCm39) |
Y130H |
probably damaging |
Het |
| Or5b121 |
T |
A |
19: 13,507,802 (GRCm39) |
I255N |
probably damaging |
Het |
| Or8b12i |
T |
A |
9: 20,082,463 (GRCm39) |
I135F |
probably damaging |
Het |
| Pgm2 |
A |
T |
5: 64,273,709 (GRCm39) |
M565L |
probably benign |
Het |
| Phactr1 |
T |
G |
13: 43,288,651 (GRCm39) |
F639V |
possibly damaging |
Het |
| Plod3 |
C |
A |
5: 137,017,571 (GRCm39) |
R165S |
probably damaging |
Het |
| Polr2b |
T |
A |
5: 77,468,193 (GRCm39) |
N164K |
probably benign |
Het |
| Rfc1 |
A |
G |
5: 65,468,382 (GRCm39) |
|
probably null |
Het |
| Rheb |
A |
G |
5: 25,012,601 (GRCm39) |
|
probably null |
Het |
| Rin2 |
C |
T |
2: 145,702,366 (GRCm39) |
T354I |
probably benign |
Het |
| Ripor2 |
G |
A |
13: 24,905,817 (GRCm39) |
|
probably null |
Het |
| Rsf1 |
ATGGCG |
ATGGCGACGGTGGCG |
7: 97,229,111 (GRCm39) |
|
probably benign |
Het |
| Scg3 |
A |
T |
9: 75,584,092 (GRCm39) |
D136E |
probably damaging |
Het |
| Slc10a4 |
C |
T |
5: 73,164,923 (GRCm39) |
L172F |
probably damaging |
Het |
| Slc35c2 |
A |
G |
2: 165,123,299 (GRCm39) |
Y113H |
probably damaging |
Het |
| Slc47a1 |
T |
A |
11: 61,235,318 (GRCm39) |
D505V |
probably benign |
Het |
| Snap29 |
C |
A |
16: 17,246,113 (GRCm39) |
D244E |
possibly damaging |
Het |
| Taar1 |
T |
C |
10: 23,797,168 (GRCm39) |
F289L |
probably benign |
Het |
| Thbs2 |
T |
A |
17: 14,893,568 (GRCm39) |
N871Y |
probably damaging |
Het |
| Tmem108 |
T |
A |
9: 103,377,162 (GRCm39) |
T96S |
possibly damaging |
Het |
| Tnk2 |
G |
T |
16: 32,489,620 (GRCm39) |
|
probably null |
Het |
| Trak1 |
T |
A |
9: 121,302,028 (GRCm39) |
M928K |
possibly damaging |
Het |
| Tuba3b |
A |
G |
6: 145,564,559 (GRCm39) |
I110V |
probably benign |
Het |
| Tyk2 |
A |
G |
9: 21,022,281 (GRCm39) |
|
probably benign |
Het |
| Ugt1a9 |
T |
A |
1: 87,998,759 (GRCm39) |
C70S |
probably benign |
Het |
| Vmn2r10 |
A |
T |
5: 109,151,410 (GRCm39) |
I68K |
possibly damaging |
Het |
| Wfs1 |
T |
C |
5: 37,124,845 (GRCm39) |
E682G |
probably damaging |
Het |
| Zfp213 |
T |
C |
17: 23,778,481 (GRCm39) |
|
probably null |
Het |
| Zfp809 |
T |
C |
9: 22,146,434 (GRCm39) |
V41A |
probably benign |
Het |
| Zfp831 |
A |
G |
2: 174,547,539 (GRCm39) |
K1574R |
possibly damaging |
Het |
|
| Other mutations in Rcbtb2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01981:Rcbtb2
|
APN |
14 |
73,402,222 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02550:Rcbtb2
|
APN |
14 |
73,399,459 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02800:Rcbtb2
|
APN |
14 |
73,405,543 (GRCm39) |
nonsense |
probably null |
|
|
IGL02811:Rcbtb2
|
APN |
14 |
73,411,851 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0319:Rcbtb2
|
UTSW |
14 |
73,415,909 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0390:Rcbtb2
|
UTSW |
14 |
73,415,987 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0448:Rcbtb2
|
UTSW |
14 |
73,415,869 (GRCm39) |
splice site |
probably benign |
|
|
R1298:Rcbtb2
|
UTSW |
14 |
73,399,828 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1567:Rcbtb2
|
UTSW |
14 |
73,399,902 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2014:Rcbtb2
|
UTSW |
14 |
73,411,826 (GRCm39) |
splice site |
probably benign |
|
|
R2218:Rcbtb2
|
UTSW |
14 |
73,416,005 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4505:Rcbtb2
|
UTSW |
14 |
73,411,345 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5832:Rcbtb2
|
UTSW |
14 |
73,404,262 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5898:Rcbtb2
|
UTSW |
14 |
73,399,405 (GRCm39) |
nonsense |
probably null |
|
|
R6484:Rcbtb2
|
UTSW |
14 |
73,414,490 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7252:Rcbtb2
|
UTSW |
14 |
73,404,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7606:Rcbtb2
|
UTSW |
14 |
73,419,806 (GRCm39) |
splice site |
probably null |
|
|
R7654:Rcbtb2
|
UTSW |
14 |
73,411,941 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7762:Rcbtb2
|
UTSW |
14 |
73,415,906 (GRCm39) |
missense |
probably benign |
|
|
R7951:Rcbtb2
|
UTSW |
14 |
73,403,992 (GRCm39) |
nonsense |
probably null |
|
|
R7960:Rcbtb2
|
UTSW |
14 |
73,399,384 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8086:Rcbtb2
|
UTSW |
14 |
73,411,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8366:Rcbtb2
|
UTSW |
14 |
73,444,632 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8696:Rcbtb2
|
UTSW |
14 |
73,404,305 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9206:Rcbtb2
|
UTSW |
14 |
73,414,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9208:Rcbtb2
|
UTSW |
14 |
73,414,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9237:Rcbtb2
|
UTSW |
14 |
73,411,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTCAGGCCAGGTTAATGACTCTG -3'
(R):5'- AGCAAACTGCCTCGTCACAG -3'
Sequencing Primer
(F):5'- CCAGGTTAATGACTCTGGAGAAAC -3'
(R):5'- AGTTTCCCTGGATGTCTTC -3'
|
| Posted On |
2014-10-01 |
Incidental Mutation