Incidental Mutation 'R2184:Cep170'
| ID |
237322 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cep170
|
| Ensembl Gene |
ENSMUSG00000057335 |
| Gene Name |
centrosomal protein 170 |
| Synonyms |
A330004A13Rik, 4933426L22Rik |
| MMRRC Submission |
040186-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.728)
|
| Stock # |
R2184 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
176561219-176641633 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 176584542 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 612
(D612E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000141793
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057037]
[ENSMUST00000192927]
[ENSMUST00000194727]
[ENSMUST00000195433]
[ENSMUST00000195717]
|
| AlphaFold |
Q6A065 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000057037
AA Change: D612E
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000059562
Gene: ENSMUSG00000057335
AA Change: D612E
| Domain | Start | End | E-Value | Type |
|---|
|
FHA
|
22 |
73 |
1.27e-7 |
SMART |
|
low complexity region
|
118 |
133 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
731 |
N/A |
INTRINSIC |
|
low complexity region
|
738 |
750 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
782 |
N/A |
INTRINSIC |
|
Pfam:CEP170_C
|
801 |
1496 |
3.3e-264 |
PFAM |
|
low complexity region
|
1533 |
1545 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192664
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192927
|
| SMART Domains |
Protein: ENSMUSP00000142032
Gene: ENSMUSG00000057335
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
17 |
N/A |
INTRINSIC |
|
Pfam:CEP170_C
|
30 |
469 |
3.4e-129 |
PFAM |
|
Pfam:CEP170_C
|
449 |
708 |
7.4e-102 |
PFAM |
|
low complexity region
|
742 |
754 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194727
AA Change: D612E
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000141793
Gene: ENSMUSG00000057335
AA Change: D612E
| Domain | Start | End | E-Value | Type |
|---|
|
FHA
|
22 |
73 |
1.27e-7 |
SMART |
|
low complexity region
|
118 |
133 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
731 |
N/A |
INTRINSIC |
|
low complexity region
|
738 |
750 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
782 |
N/A |
INTRINSIC |
|
Pfam:CEP170_C
|
795 |
1509 |
8e-260 |
PFAM |
|
low complexity region
|
1543 |
1555 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194984
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195121
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195433
|
| SMART Domains |
Protein: ENSMUSP00000142108
Gene: ENSMUSG00000057335
| Domain | Start | End | E-Value | Type |
|---|
|
FHA
|
22 |
73 |
6.1e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195717
AA Change: D612E
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000141769
Gene: ENSMUSG00000057335
AA Change: D612E
| Domain | Start | End | E-Value | Type |
|---|
|
FHA
|
22 |
73 |
1.27e-7 |
SMART |
|
low complexity region
|
118 |
133 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
731 |
N/A |
INTRINSIC |
|
low complexity region
|
738 |
750 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
782 |
N/A |
INTRINSIC |
|
Pfam:CEP170_C
|
795 |
1499 |
1.8e-261 |
PFAM |
|
low complexity region
|
1533 |
1545 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195463
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
All alleles(29) : Gene trapped(29)
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700088E04Rik |
T |
C |
15: 79,019,389 (GRCm39) |
R184G |
probably damaging |
Het |
| 2300002M23Rik |
C |
A |
17: 35,879,115 (GRCm39) |
A151E |
probably benign |
Het |
| A930011G23Rik |
C |
T |
5: 99,380,228 (GRCm39) |
R339Q |
possibly damaging |
Het |
| Abcd2 |
T |
C |
15: 91,075,642 (GRCm39) |
Y57C |
probably benign |
Het |
| Adprhl1 |
A |
G |
8: 13,292,559 (GRCm39) |
V244A |
probably benign |
Het |
| Agl |
T |
C |
3: 116,574,426 (GRCm39) |
N753D |
probably benign |
Het |
| Amotl1 |
T |
A |
9: 14,486,686 (GRCm39) |
M440L |
probably benign |
Het |
| Angpt2 |
A |
G |
8: 18,742,132 (GRCm39) |
Y475H |
probably benign |
Het |
| Angpt4 |
A |
T |
2: 151,780,874 (GRCm39) |
H374L |
probably damaging |
Het |
| Ank1 |
A |
T |
8: 23,599,270 (GRCm39) |
T801S |
probably damaging |
Het |
| Ap5m1 |
G |
T |
14: 49,323,752 (GRCm39) |
A481S |
probably damaging |
Het |
| AY358078 |
G |
T |
14: 52,063,445 (GRCm39) |
G364W |
probably damaging |
Het |
| C4b |
C |
A |
17: 34,956,676 (GRCm39) |
A641S |
probably benign |
Het |
| Capn13 |
T |
C |
17: 73,672,943 (GRCm39) |
Y120C |
probably damaging |
Het |
| Cbx6 |
T |
C |
15: 79,712,762 (GRCm39) |
T222A |
probably benign |
Het |
| Cckar |
T |
C |
5: 53,860,254 (GRCm39) |
T192A |
probably damaging |
Het |
| Cdc42bpb |
T |
C |
12: 111,262,478 (GRCm39) |
D30G |
probably damaging |
Het |
| Cdk18 |
A |
G |
1: 132,043,690 (GRCm39) |
Y385H |
probably damaging |
Het |
| Dennd4b |
G |
T |
3: 90,182,847 (GRCm39) |
R888L |
probably damaging |
Het |
| Egf |
A |
T |
3: 129,517,007 (GRCm39) |
C373* |
probably null |
Het |
| Gabrb2 |
T |
C |
11: 42,312,255 (GRCm39) |
|
probably null |
Het |
| Gle1 |
G |
T |
2: 29,839,030 (GRCm39) |
A482S |
probably damaging |
Het |
| Gm10644 |
T |
C |
8: 84,660,256 (GRCm39) |
T30A |
possibly damaging |
Het |
| Gmnn |
A |
G |
13: 24,937,706 (GRCm39) |
Y95H |
probably damaging |
Het |
| Hectd3 |
T |
A |
4: 116,858,100 (GRCm39) |
S643T |
possibly damaging |
Het |
| Hoga1 |
A |
G |
19: 42,049,830 (GRCm39) |
Y225C |
probably damaging |
Het |
| Hook3 |
T |
C |
8: 26,609,011 (GRCm39) |
E11G |
probably benign |
Het |
| Hsd17b1 |
C |
A |
11: 100,969,357 (GRCm39) |
S30R |
probably benign |
Het |
| Htr3b |
G |
A |
9: 48,858,544 (GRCm39) |
P112S |
probably damaging |
Het |
| Iqch |
T |
A |
9: 63,432,351 (GRCm39) |
D348V |
probably damaging |
Het |
| Irgm2 |
A |
T |
11: 58,111,254 (GRCm39) |
N327I |
probably benign |
Het |
| Itgb4 |
T |
C |
11: 115,870,450 (GRCm39) |
I93T |
probably damaging |
Het |
| Lamb2 |
T |
C |
9: 108,357,752 (GRCm39) |
F92L |
probably damaging |
Het |
| Lats2 |
T |
C |
14: 57,929,016 (GRCm39) |
H953R |
probably damaging |
Het |
| Lrp1b |
T |
C |
2: 40,620,714 (GRCm39) |
E3588G |
probably benign |
Het |
| Marchf1 |
A |
G |
8: 66,840,075 (GRCm39) |
E286G |
probably benign |
Het |
| Mc2r |
G |
T |
18: 68,541,196 (GRCm39) |
F32L |
probably benign |
Het |
| Mink1 |
C |
T |
11: 70,494,623 (GRCm39) |
T268M |
probably damaging |
Het |
| Mta1 |
G |
A |
12: 113,093,815 (GRCm39) |
|
probably null |
Het |
| Muc5b |
C |
A |
7: 141,412,601 (GRCm39) |
S1849* |
probably null |
Het |
| Myh15 |
A |
G |
16: 48,957,874 (GRCm39) |
E897G |
probably damaging |
Het |
| Nobox |
T |
C |
6: 43,281,819 (GRCm39) |
Q418R |
possibly damaging |
Het |
| Obsl1 |
G |
T |
1: 75,478,861 (GRCm39) |
Q626K |
probably benign |
Het |
| Or11h4 |
A |
G |
14: 50,974,059 (GRCm39) |
S187P |
probably damaging |
Het |
| Or13a24 |
T |
C |
7: 140,154,315 (GRCm39) |
V83A |
probably benign |
Het |
| Or1j12 |
A |
G |
2: 36,343,046 (GRCm39) |
T150A |
probably benign |
Het |
| Or2w25 |
T |
A |
11: 59,503,964 (GRCm39) |
M58K |
probably damaging |
Het |
| Or5w14 |
G |
A |
2: 87,541,549 (GRCm39) |
R234C |
probably damaging |
Het |
| Or8k24 |
G |
A |
2: 86,216,489 (GRCm39) |
T91I |
probably benign |
Het |
| Or9i1 |
A |
G |
19: 13,839,399 (GRCm39) |
I81V |
probably benign |
Het |
| Pald1 |
C |
T |
10: 61,182,915 (GRCm39) |
A345T |
possibly damaging |
Het |
| Pde8b |
G |
A |
13: 95,162,723 (GRCm39) |
P800S |
probably damaging |
Het |
| Pgm2l1 |
G |
A |
7: 99,917,362 (GRCm39) |
C493Y |
possibly damaging |
Het |
| Pias3 |
A |
G |
3: 96,609,537 (GRCm39) |
S311G |
possibly damaging |
Het |
| Pkhd1l1 |
A |
G |
15: 44,362,692 (GRCm39) |
N573D |
possibly damaging |
Het |
| Plaat3 |
A |
G |
19: 7,556,583 (GRCm39) |
D128G |
probably damaging |
Het |
| Plxnc1 |
T |
G |
10: 94,780,131 (GRCm39) |
S104R |
probably damaging |
Het |
| Pofut2 |
T |
A |
10: 77,103,059 (GRCm39) |
F179I |
probably damaging |
Het |
| Prkcsh |
T |
A |
9: 21,916,028 (GRCm39) |
C112S |
probably damaging |
Het |
| Prss32 |
G |
A |
17: 24,078,297 (GRCm39) |
A328T |
probably benign |
Het |
| Ptgir |
G |
T |
7: 16,642,708 (GRCm39) |
R103L |
probably damaging |
Het |
| Ptpn5 |
G |
A |
7: 46,738,350 (GRCm39) |
S244F |
probably damaging |
Het |
| Rnpepl1 |
G |
A |
1: 92,844,545 (GRCm39) |
V346I |
probably benign |
Het |
| Sh3rf1 |
T |
A |
8: 61,825,688 (GRCm39) |
V561D |
probably damaging |
Het |
| Slc22a19 |
A |
T |
19: 7,687,026 (GRCm39) |
Y160N |
probably benign |
Het |
| Sorbs3 |
A |
G |
14: 70,428,880 (GRCm39) |
|
probably null |
Het |
| Sostdc1 |
T |
G |
12: 36,367,295 (GRCm39) |
I157S |
probably damaging |
Het |
| Svil |
G |
T |
18: 5,099,534 (GRCm39) |
R1777L |
probably damaging |
Het |
| Svil |
A |
T |
18: 5,099,615 (GRCm39) |
E1804V |
probably damaging |
Het |
| Tasor |
T |
A |
14: 27,188,141 (GRCm39) |
N862K |
possibly damaging |
Het |
| Thbs4 |
A |
G |
13: 92,911,302 (GRCm39) |
S294P |
probably benign |
Het |
| Tle2 |
A |
G |
10: 81,426,111 (GRCm39) |
Y750C |
probably damaging |
Het |
| Tmcc3 |
T |
C |
10: 94,418,168 (GRCm39) |
L312P |
probably damaging |
Het |
| Tnip2 |
TCTCCT |
TCT |
5: 34,656,957 (GRCm39) |
|
probably benign |
Het |
| Tnpo2 |
T |
A |
8: 85,780,475 (GRCm39) |
M734K |
probably benign |
Het |
| Trmt2a |
A |
T |
16: 18,070,859 (GRCm39) |
R531W |
probably benign |
Het |
| Ubn2 |
C |
T |
6: 38,461,029 (GRCm39) |
R483W |
probably damaging |
Het |
| Zc3hav1 |
T |
A |
6: 38,284,343 (GRCm39) |
Y924F |
probably damaging |
Het |
|
| Other mutations in Cep170 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00773:Cep170
|
APN |
1 |
176,582,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00925:Cep170
|
APN |
1 |
176,621,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00972:Cep170
|
APN |
1 |
176,563,262 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01488:Cep170
|
APN |
1 |
176,583,941 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01916:Cep170
|
APN |
1 |
176,567,476 (GRCm39) |
splice site |
probably benign |
|
|
IGL02212:Cep170
|
APN |
1 |
176,563,502 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02269:Cep170
|
APN |
1 |
176,596,932 (GRCm39) |
missense |
probably benign |
|
|
IGL02732:Cep170
|
APN |
1 |
176,564,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02740:Cep170
|
APN |
1 |
176,621,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02812:Cep170
|
APN |
1 |
176,570,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03036:Cep170
|
APN |
1 |
176,596,903 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL03201:Cep170
|
APN |
1 |
176,564,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03333:Cep170
|
APN |
1 |
176,597,092 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
BB003:Cep170
|
UTSW |
1 |
176,588,979 (GRCm39) |
missense |
probably damaging |
0.97 |
|
BB013:Cep170
|
UTSW |
1 |
176,588,979 (GRCm39) |
missense |
probably damaging |
0.97 |
|
PIT4520001:Cep170
|
UTSW |
1 |
176,607,765 (GRCm39) |
missense |
unknown |
|
|
R0031:Cep170
|
UTSW |
1 |
176,583,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0039:Cep170
|
UTSW |
1 |
176,610,061 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0053:Cep170
|
UTSW |
1 |
176,609,946 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0053:Cep170
|
UTSW |
1 |
176,609,946 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0113:Cep170
|
UTSW |
1 |
176,586,021 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0144:Cep170
|
UTSW |
1 |
176,620,161 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0613:Cep170
|
UTSW |
1 |
176,602,246 (GRCm39) |
missense |
probably benign |
|
|
R0755:Cep170
|
UTSW |
1 |
176,583,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1132:Cep170
|
UTSW |
1 |
176,577,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1367:Cep170
|
UTSW |
1 |
176,563,290 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1399:Cep170
|
UTSW |
1 |
176,585,969 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1462:Cep170
|
UTSW |
1 |
176,584,211 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1462:Cep170
|
UTSW |
1 |
176,584,211 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1481:Cep170
|
UTSW |
1 |
176,609,951 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1526:Cep170
|
UTSW |
1 |
176,616,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1540:Cep170
|
UTSW |
1 |
176,567,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1552:Cep170
|
UTSW |
1 |
176,610,060 (GRCm39) |
splice site |
probably benign |
|
|
R1570:Cep170
|
UTSW |
1 |
176,583,367 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1846:Cep170
|
UTSW |
1 |
176,583,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1884:Cep170
|
UTSW |
1 |
176,602,245 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1945:Cep170
|
UTSW |
1 |
176,621,100 (GRCm39) |
nonsense |
probably null |
|
|
R1954:Cep170
|
UTSW |
1 |
176,583,950 (GRCm39) |
missense |
probably benign |
|
|
R1957:Cep170
|
UTSW |
1 |
176,597,013 (GRCm39) |
missense |
probably benign |
0.24 |
|
R2280:Cep170
|
UTSW |
1 |
176,602,071 (GRCm39) |
missense |
probably benign |
0.17 |
|
R2426:Cep170
|
UTSW |
1 |
176,602,201 (GRCm39) |
missense |
probably benign |
|
|
R3415:Cep170
|
UTSW |
1 |
176,583,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3417:Cep170
|
UTSW |
1 |
176,583,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3752:Cep170
|
UTSW |
1 |
176,610,061 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R3848:Cep170
|
UTSW |
1 |
176,583,409 (GRCm39) |
missense |
probably benign |
0.14 |
|
R3849:Cep170
|
UTSW |
1 |
176,583,409 (GRCm39) |
missense |
probably benign |
0.14 |
|
R4752:Cep170
|
UTSW |
1 |
176,584,254 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4910:Cep170
|
UTSW |
1 |
176,609,829 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5007:Cep170
|
UTSW |
1 |
176,597,380 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5052:Cep170
|
UTSW |
1 |
176,621,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5093:Cep170
|
UTSW |
1 |
176,596,896 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5530:Cep170
|
UTSW |
1 |
176,597,076 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5622:Cep170
|
UTSW |
1 |
176,563,433 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R5892:Cep170
|
UTSW |
1 |
176,582,953 (GRCm39) |
splice site |
probably null |
|
|
R5942:Cep170
|
UTSW |
1 |
176,583,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6083:Cep170
|
UTSW |
1 |
176,602,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6091:Cep170
|
UTSW |
1 |
176,583,397 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6190:Cep170
|
UTSW |
1 |
176,609,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6253:Cep170
|
UTSW |
1 |
176,607,960 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6476:Cep170
|
UTSW |
1 |
176,607,917 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6622:Cep170
|
UTSW |
1 |
176,583,898 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6932:Cep170
|
UTSW |
1 |
176,589,003 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7030:Cep170
|
UTSW |
1 |
176,584,051 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7163:Cep170
|
UTSW |
1 |
176,602,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7352:Cep170
|
UTSW |
1 |
176,597,423 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7499:Cep170
|
UTSW |
1 |
176,602,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7502:Cep170
|
UTSW |
1 |
176,583,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7773:Cep170
|
UTSW |
1 |
176,567,642 (GRCm39) |
missense |
|
|
|
R7926:Cep170
|
UTSW |
1 |
176,588,979 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8043:Cep170
|
UTSW |
1 |
176,596,808 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8203:Cep170
|
UTSW |
1 |
176,596,877 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8350:Cep170
|
UTSW |
1 |
176,564,445 (GRCm39) |
missense |
|
|
|
R8450:Cep170
|
UTSW |
1 |
176,564,445 (GRCm39) |
missense |
|
|
|
R8835:Cep170
|
UTSW |
1 |
176,584,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8931:Cep170
|
UTSW |
1 |
176,597,377 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9108:Cep170
|
UTSW |
1 |
176,616,051 (GRCm39) |
nonsense |
probably null |
|
|
R9323:Cep170
|
UTSW |
1 |
176,586,068 (GRCm39) |
missense |
probably benign |
|
|
R9586:Cep170
|
UTSW |
1 |
176,563,463 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9629:Cep170
|
UTSW |
1 |
176,583,821 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTCGCTTTGGTATACCTGGGC -3'
(R):5'- TGCTAAAAGCTAAGATATTTTGCCC -3'
Sequencing Primer
(F):5'- TGCAGTTCCGTGTCTTGC -3'
(R):5'- GGCATTCATTTTATACTGAGG -3'
|
| Posted On |
2014-10-02 |
Incidental Mutation