Incidental Mutation 'IGL01917:Gm5862'
ID279107
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5862
Ensembl Gene ENSMUSG00000067700
Gene Namepredicted gene 5862
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.188) question?
Stock #IGL01917
Quality Score
Status
Chromosome5
Chromosomal Location26017278-26022916 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to C at 26022771 bp
ZygosityHeterozygous
Amino Acid Change Tryptophan to Glycine at position 41 (W41G)
Ref Sequence ENSEMBL: ENSMUSP00000072133 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072286]
Predicted Effect probably benign
Transcript: ENSMUST00000072286
AA Change: W41G

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000072133
Gene: ENSMUSG00000067700
AA Change: W41G

DomainStartEndE-ValueType
Pfam:Takusan 50 134 1.6e-25 PFAM
low complexity region 154 168 N/A INTRINSIC
low complexity region 235 259 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 23 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abt1 A T 13: 23,423,789 M15K unknown Het
Adal A G 2: 121,142,554 S31G possibly damaging Het
C2cd5 T C 6: 143,072,596 Y300C probably benign Het
Chia1 T A 3: 106,128,220 V184E probably damaging Het
Fat4 T A 3: 38,889,730 V924D possibly damaging Het
Fstl5 A T 3: 76,707,846 H738L probably damaging Het
Gimap4 T C 6: 48,690,920 M75T probably benign Het
Gm10238 A T 15: 75,237,712 noncoding transcript Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm21738 G A 14: 19,416,979 S144L probably benign Het
Gsdmc A G 15: 63,778,585 Y307H probably benign Het
Iqub A G 6: 24,479,319 L408P probably damaging Het
Lbx1 T A 19: 45,234,213 K124* probably null Het
Naip2 C A 13: 100,162,083 V482L probably benign Het
Olfr596 T A 7: 103,310,357 L212* probably null Het
Pdcd11 C A 19: 47,101,165 Q325K possibly damaging Het
Pik3c3 T A 18: 30,274,446 S82R probably damaging Het
Pramef6 T A 4: 143,897,714 E71V probably benign Het
Prickle1 T C 15: 93,503,527 K359E probably damaging Het
Ptprj A G 2: 90,469,749 V236A probably damaging Het
Serpinb3d T A 1: 107,079,681 T192S probably damaging Het
Usp31 T C 7: 121,679,485 N219S probably benign Het
Vmn2r-ps159 C T 4: 156,338,254 noncoding transcript Het
Other mutations in Gm5862
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01606:Gm5862 APN 5 26019516 missense probably benign
IGL01863:Gm5862 APN 5 26022771 missense probably benign
IGL01868:Gm5862 APN 5 26022771 missense probably benign
IGL01873:Gm5862 APN 5 26022771 missense probably benign
IGL01881:Gm5862 APN 5 26022771 missense probably benign
IGL01902:Gm5862 APN 5 26022771 missense probably benign
IGL01905:Gm5862 APN 5 26022771 missense probably benign
IGL01909:Gm5862 APN 5 26022771 missense probably benign
IGL01924:Gm5862 APN 5 26022771 missense probably benign
IGL01927:Gm5862 APN 5 26022771 missense probably benign
IGL01951:Gm5862 APN 5 26022771 missense probably benign
IGL03374:Gm5862 APN 5 26019512 missense probably damaging 0.98
R2475:Gm5862 UTSW 5 26019492 missense probably damaging 1.00
R3828:Gm5862 UTSW 5 26019347 missense probably benign 0.27
R4591:Gm5862 UTSW 5 26019488 missense possibly damaging 0.95
R6916:Gm5862 UTSW 5 26019348 missense probably benign
R8291:Gm5862 UTSW 5 26019446 missense probably benign 0.32
Z1176:Gm5862 UTSW 5 26018487 frame shift probably null
Posted On2015-04-16