Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01951:Gm5862'

279192

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm5862

Ensembl Gene

ENSMUSG00000067700

Gene Name

predicted gene 5862

Synonyms

Accession Numbers

Is this an essential gene?

Possibly non essential (E-score: 0.253) question?

Stock #

IGL01951

Quality Score

Status

Chromosome

Chromosomal Location

26017278-26022916 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 26022771 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Glycine at position 41 (W41G)

Ref Sequence

ENSEMBL: ENSMUSP00000072133 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000072286]

AlphaFold

K7N5V5

Predicted Effect

probably benign
Transcript: ENSMUST00000072286
AA Change: W41G

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000072133
Gene: ENSMUSG00000067700
AA Change: W41G

Domain	Start	End	E-Value	Type
Pfam:Takusan	50	134	1.6e-25	PFAM
low complexity region	154	168	N/A	INTRINSIC
low complexity region	235	259	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921539E11Rik	A	G	4: 103,235,668	I152T	probably damaging	Het
A2m	C	T	6: 121,667,190	T949I	possibly damaging	Het
Begain	T	A	12: 109,033,645	Y605F	probably benign	Het
C130026I21Rik	A	G	1: 85,254,186		probably benign	Het
Cavin2	A	G	1: 51,289,411	E9G	possibly damaging	Het
Cdh16	A	G	8: 104,617,691	V72A	probably damaging	Het
Dgkd	T	C	1: 87,916,916	L268P	probably damaging	Het
Eps8	T	A	6: 137,537,671	Y28F	possibly damaging	Het
Erap1	T	C	13: 74,675,295	I816T	probably damaging	Het
Fli1	A	T	9: 32,461,364	F126Y	probably damaging	Het
Gm10717	C	T	9: 3,025,616	S67L	probably benign	Het
Gm10718	A	T	9: 3,025,118	Y194F	probably benign	Het
Gm21957	A	T	7: 125,219,832		noncoding transcript	Het
Gm9833	G	A	3: 10,089,058	V296M	probably damaging	Het
Hectd1	T	A	12: 51,794,497	R618*	probably null	Het
Homez	T	C	14: 54,858,176	E25G	probably damaging	Het
Ifngr1	C	A	10: 19,609,454	N400K	possibly damaging	Het
Lin7a	G	A	10: 107,412,025	V186I	possibly damaging	Het
Lpcat2	G	T	8: 92,918,047	S448I	probably damaging	Het
Lrp10	C	A	14: 54,468,662	Y436*	probably null	Het
Myo1f	A	G	17: 33,598,017	H707R	possibly damaging	Het
Neurl4	A	G	11: 69,909,623	N1147D	probably damaging	Het
Olfr1272	G	T	2: 90,282,007	D189E	probably damaging	Het
Olfr1414	T	C	1: 92,511,131	D299G	probably null	Het
Pak6	T	C	2: 118,693,260	S299P	probably benign	Het
Panx2	A	G	15: 89,068,767	D487G	probably damaging	Het
Sbspon	T	C	1: 15,858,934	N211S	probably benign	Het
Sgsm1	T	A	5: 113,286,767		probably benign	Het
Slc38a4	T	C	15: 97,019,763	Y27C	probably benign	Het
Sorbs1	A	G	19: 40,318,016		probably benign	Het
Ssh1	A	T	5: 113,966,247	Y35N	possibly damaging	Het
Stx2	A	T	5: 128,992,265	F127L	probably damaging	Het
Synm	A	T	7: 67,739,137	I325N	probably damaging	Het
Szt2	A	G	4: 118,376,493		probably benign	Het
Tbc1d23	A	G	16: 57,186,685		probably benign	Het
Tmem50a	T	C	4: 134,898,428		probably benign	Het
Tpx2	T	G	2: 152,884,176	L354V	probably benign	Het
Trafd1	G	A	5: 121,374,031	R399C	possibly damaging	Het
Trem3	C	T	17: 48,249,875	R125W	probably damaging	Het
Ubp1	T	A	9: 113,951,618	Y92*	probably null	Het
Wnk1	T	A	6: 119,963,485	T62S	probably damaging	Het
Zbtb6	T	C	2: 37,429,331	E195G	probably benign	Het
Zc3h15	A	G	2: 83,661,485	D306G	probably damaging	Het

Other mutations in Gm5862

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01606:Gm5862	APN	5	26019516	missense	probably benign
IGL01863:Gm5862	APN	5	26022771	missense	probably benign
IGL01868:Gm5862	APN	5	26022771	missense	probably benign
IGL01873:Gm5862	APN	5	26022771	missense	probably benign
IGL01881:Gm5862	APN	5	26022771	missense	probably benign
IGL01902:Gm5862	APN	5	26022771	missense	probably benign
IGL01905:Gm5862	APN	5	26022771	missense	probably benign
IGL01909:Gm5862	APN	5	26022771	missense	probably benign
IGL01917:Gm5862	APN	5	26022771	missense	probably benign
IGL01924:Gm5862	APN	5	26022771	missense	probably benign
IGL01927:Gm5862	APN	5	26022771	missense	probably benign
IGL03374:Gm5862	APN	5	26019512	missense	probably damaging	0.98
R2475:Gm5862	UTSW	5	26019492	missense	probably damaging	1.00
R3828:Gm5862	UTSW	5	26019347	missense	probably benign	0.27
R4591:Gm5862	UTSW	5	26019488	missense	possibly damaging	0.95
R6916:Gm5862	UTSW	5	26019348	missense	probably benign
R8291:Gm5862	UTSW	5	26019446	missense	probably benign	0.32
R8927:Gm5862	UTSW	5	26021680	missense	probably damaging	0.98
R8928:Gm5862	UTSW	5	26021680	missense	probably damaging	0.98
R9074:Gm5862	UTSW	5	26021626	missense	probably damaging	0.98
Z1176:Gm5862	UTSW	5	26018487	frame shift	probably null

Posted On

2015-04-16