Incidental Mutation 'IGL01951:Gm5862'
ID279192
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5862
Ensembl Gene ENSMUSG00000067700
Gene Namepredicted gene 5862
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.144) question?
Stock #IGL01951
Quality Score
Status
Chromosome5
Chromosomal Location26017278-26022916 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to C at 26022771 bp
ZygosityHeterozygous
Amino Acid Change Tryptophan to Glycine at position 41 (W41G)
Ref Sequence ENSEMBL: ENSMUSP00000072133 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072286]
Predicted Effect probably benign
Transcript: ENSMUST00000072286
AA Change: W41G

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000072133
Gene: ENSMUSG00000067700
AA Change: W41G

DomainStartEndE-ValueType
Pfam:Takusan 50 134 1.6e-25 PFAM
low complexity region 154 168 N/A INTRINSIC
low complexity region 235 259 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4921539E11Rik A G 4: 103,235,668 I152T probably damaging Het
A2m C T 6: 121,667,190 T949I possibly damaging Het
Begain T A 12: 109,033,645 Y605F probably benign Het
C130026I21Rik A G 1: 85,254,186 probably benign Het
Cavin2 A G 1: 51,289,411 E9G possibly damaging Het
Cdh16 A G 8: 104,617,691 V72A probably damaging Het
Dgkd T C 1: 87,916,916 L268P probably damaging Het
Eps8 T A 6: 137,537,671 Y28F possibly damaging Het
Erap1 T C 13: 74,675,295 I816T probably damaging Het
Fli1 A T 9: 32,461,364 F126Y probably damaging Het
Gm10717 C T 9: 3,025,616 S67L probably benign Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm21957 A T 7: 125,219,832 noncoding transcript Het
Gm9833 G A 3: 10,089,058 V296M probably damaging Het
Hectd1 T A 12: 51,794,497 R618* probably null Het
Homez T C 14: 54,858,176 E25G probably damaging Het
Ifngr1 C A 10: 19,609,454 N400K possibly damaging Het
Lin7a G A 10: 107,412,025 V186I possibly damaging Het
Lpcat2 G T 8: 92,918,047 S448I probably damaging Het
Lrp10 C A 14: 54,468,662 Y436* probably null Het
Myo1f A G 17: 33,598,017 H707R possibly damaging Het
Neurl4 A G 11: 69,909,623 N1147D probably damaging Het
Olfr1272 G T 2: 90,282,007 D189E probably damaging Het
Olfr1414 T C 1: 92,511,131 D299G probably null Het
Pak6 T C 2: 118,693,260 S299P probably benign Het
Panx2 A G 15: 89,068,767 D487G probably damaging Het
Sbspon T C 1: 15,858,934 N211S probably benign Het
Sgsm1 T A 5: 113,286,767 probably benign Het
Slc38a4 T C 15: 97,019,763 Y27C probably benign Het
Sorbs1 A G 19: 40,318,016 probably benign Het
Ssh1 A T 5: 113,966,247 Y35N possibly damaging Het
Stx2 A T 5: 128,992,265 F127L probably damaging Het
Synm A T 7: 67,739,137 I325N probably damaging Het
Szt2 A G 4: 118,376,493 probably benign Het
Tbc1d23 A G 16: 57,186,685 probably benign Het
Tmem50a T C 4: 134,898,428 probably benign Het
Tpx2 T G 2: 152,884,176 L354V probably benign Het
Trafd1 G A 5: 121,374,031 R399C possibly damaging Het
Trem3 C T 17: 48,249,875 R125W probably damaging Het
Ubp1 T A 9: 113,951,618 Y92* probably null Het
Wnk1 T A 6: 119,963,485 T62S probably damaging Het
Zbtb6 T C 2: 37,429,331 E195G probably benign Het
Zc3h15 A G 2: 83,661,485 D306G probably damaging Het
Other mutations in Gm5862
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01606:Gm5862 APN 5 26019516 missense probably benign
IGL01863:Gm5862 APN 5 26022771 missense probably benign
IGL01868:Gm5862 APN 5 26022771 missense probably benign
IGL01873:Gm5862 APN 5 26022771 missense probably benign
IGL01881:Gm5862 APN 5 26022771 missense probably benign
IGL01902:Gm5862 APN 5 26022771 missense probably benign
IGL01905:Gm5862 APN 5 26022771 missense probably benign
IGL01909:Gm5862 APN 5 26022771 missense probably benign
IGL01917:Gm5862 APN 5 26022771 missense probably benign
IGL01924:Gm5862 APN 5 26022771 missense probably benign
IGL01927:Gm5862 APN 5 26022771 missense probably benign
IGL03374:Gm5862 APN 5 26019512 missense probably damaging 0.98
R2475:Gm5862 UTSW 5 26019492 missense probably damaging 1.00
R3828:Gm5862 UTSW 5 26019347 missense probably benign 0.27
R4591:Gm5862 UTSW 5 26019488 missense possibly damaging 0.95
R6916:Gm5862 UTSW 5 26019348 missense probably benign
R8291:Gm5862 UTSW 5 26019446 missense probably benign 0.32
Z1176:Gm5862 UTSW 5 26018487 frame shift probably null
Posted On2015-04-16