|Institutional Source||Beutler Lab|
|Gene Name||IK cytokine|
|Is this an essential gene?||Probably essential (E-score: 0.969)|
|Stock #||R4819 (G1)|
|Chromosomal Location||36744656-36757639 bp(+) (GRCm38)|
|Type of Mutation||splice site|
|DNA Base Change (assembly)||T to A at 36753257 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000007042 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000007042]|
|Predicted Effect||probably null
|Predicted Effect||noncoding transcript
|Coding Region Coverage||
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2. [provided by RefSeq, Jul 2008]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Ik||
(F):5'- TTGGGTTTGAAGCATCAAGGAG -3'
(R):5'- TGGGAAAACCAGGTTCCAC -3'
(F):5'- TACCAGGTACATATGTGGTGCAC -3'
(R):5'- TGGGAAAACCAGGTTCCACTAATTG -3'