Incidental Mutation 'R7619:Pcdhga9'
| ID |
589079 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdhga9
|
| Ensembl Gene |
ENSMUSG00000102440 |
| Gene Name |
protocadherin gamma subfamily A, 9 |
| Synonyms |
|
| MMRRC Submission |
045686-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.120)
|
| Stock # |
R7619 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
37869989-37974916 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 37871805 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Glycine
at position 545
(S545G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000089555
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000003599]
[ENSMUST00000066149]
[ENSMUST00000073447]
[ENSMUST00000091935]
[ENSMUST00000115661]
[ENSMUST00000192511]
[ENSMUST00000192535]
[ENSMUST00000192931]
[ENSMUST00000193414]
[ENSMUST00000193869]
[ENSMUST00000194190]
[ENSMUST00000194418]
[ENSMUST00000194544]
[ENSMUST00000195112]
[ENSMUST00000195363]
[ENSMUST00000195823]
|
| AlphaFold |
Q91XX9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000003599
|
| SMART Domains |
Protein: ENSMUSP00000003599
Gene: ENSMUSG00000103088
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
47 |
131 |
8.06e-6 |
SMART |
|
CA
|
155 |
240 |
2.29e-19 |
SMART |
|
CA
|
264 |
345 |
3.36e-26 |
SMART |
|
CA
|
369 |
450 |
4.94e-24 |
SMART |
|
CA
|
474 |
560 |
7.6e-25 |
SMART |
|
CA
|
591 |
672 |
9.18e-10 |
SMART |
|
Pfam:Cadherin_C_2
|
687 |
768 |
3.5e-20 |
PFAM |
|
Pfam:Cadherin_tail
|
807 |
930 |
8.1e-38 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000066149
|
| SMART Domains |
Protein: ENSMUSP00000067728
Gene: ENSMUSG00000103897
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
29 |
N/A |
INTRINSIC |
|
CA
|
31 |
131 |
4.84e-2 |
SMART |
|
CA
|
155 |
240 |
1.48e-22 |
SMART |
|
CA
|
264 |
345 |
1.14e-23 |
SMART |
|
CA
|
369 |
450 |
9.44e-21 |
SMART |
|
CA
|
474 |
560 |
1.03e-26 |
SMART |
|
CA
|
591 |
669 |
3.64e-13 |
SMART |
|
Pfam:Cadherin_C_2
|
688 |
772 |
3e-25 |
PFAM |
|
Pfam:Cadherin_tail
|
809 |
932 |
8.1e-38 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000073447
|
| SMART Domains |
Protein: ENSMUSP00000073150
Gene: ENSMUSG00000104346
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
CA
|
42 |
128 |
2.15e-2 |
SMART |
|
CA
|
152 |
237 |
4.8e-13 |
SMART |
|
CA
|
261 |
342 |
9.36e-25 |
SMART |
|
CA
|
366 |
447 |
6.62e-25 |
SMART |
|
CA
|
471 |
557 |
6.72e-26 |
SMART |
|
CA
|
588 |
666 |
2.15e-15 |
SMART |
|
Pfam:Cadherin_C_2
|
685 |
768 |
4.8e-24 |
PFAM |
|
Pfam:Cadherin_tail
|
805 |
928 |
8.1e-38 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000091935
AA Change: S545G
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000089555
Gene: ENSMUSG00000102440
AA Change: S545G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
29 |
N/A |
INTRINSIC |
|
CA
|
32 |
132 |
8.37e-3 |
SMART |
|
CA
|
156 |
241 |
5.51e-22 |
SMART |
|
CA
|
265 |
346 |
8.27e-26 |
SMART |
|
CA
|
370 |
451 |
1.4e-23 |
SMART |
|
CA
|
475 |
561 |
2.97e-27 |
SMART |
|
CA
|
592 |
670 |
1.18e-12 |
SMART |
|
Pfam:Cadherin_C_2
|
688 |
772 |
3.9e-24 |
PFAM |
|
Pfam:Cadherin_tail
|
809 |
932 |
8.1e-38 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115661
|
| SMART Domains |
Protein: ENSMUSP00000111325
Gene: ENSMUSG00000103458
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
20 |
131 |
5.3e-2 |
SMART |
|
CA
|
155 |
240 |
1.51e-19 |
SMART |
|
CA
|
264 |
348 |
7.6e-25 |
SMART |
|
CA
|
372 |
453 |
1.42e-24 |
SMART |
|
CA
|
477 |
563 |
1.42e-24 |
SMART |
|
CA
|
594 |
674 |
4.12e-12 |
SMART |
|
low complexity region
|
706 |
721 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_tail
|
796 |
930 |
3.9e-58 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192511
|
| SMART Domains |
Protein: ENSMUSP00000141704
Gene: ENSMUSG00000103472
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
47 |
133 |
1.57e-2 |
SMART |
|
CA
|
157 |
242 |
3.24e-19 |
SMART |
|
CA
|
266 |
347 |
3.21e-23 |
SMART |
|
CA
|
371 |
452 |
9.08e-23 |
SMART |
|
CA
|
476 |
562 |
1.32e-24 |
SMART |
|
CA
|
593 |
671 |
3.5e-15 |
SMART |
|
transmembrane domain
|
694 |
716 |
N/A |
INTRINSIC |
|
low complexity region
|
916 |
935 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192535
|
| SMART Domains |
Protein: ENSMUSP00000142010
Gene: ENSMUSG00000103749
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
25 |
N/A |
INTRINSIC |
|
CA
|
56 |
131 |
8e-3 |
SMART |
|
CA
|
155 |
240 |
2.49e-20 |
SMART |
|
CA
|
264 |
341 |
4.97e-29 |
SMART |
|
CA
|
365 |
446 |
1.09e-25 |
SMART |
|
CA
|
470 |
556 |
1.75e-24 |
SMART |
|
CA
|
587 |
668 |
9.18e-10 |
SMART |
|
transmembrane domain
|
687 |
709 |
N/A |
INTRINSIC |
|
low complexity region
|
907 |
926 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192931
|
| SMART Domains |
Protein: ENSMUSP00000141348
Gene: ENSMUSG00000103037
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
36 |
119 |
8e-3 |
SMART |
|
CA
|
143 |
228 |
1.34e-20 |
SMART |
|
CA
|
252 |
333 |
1.52e-24 |
SMART |
|
CA
|
357 |
438 |
9.22e-24 |
SMART |
|
CA
|
462 |
548 |
1.24e-24 |
SMART |
|
CA
|
579 |
660 |
1.3e-9 |
SMART |
|
transmembrane domain
|
679 |
701 |
N/A |
INTRINSIC |
|
low complexity region
|
899 |
918 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193414
|
| SMART Domains |
Protein: ENSMUSP00000141893
Gene: ENSMUSG00000103567
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
45 |
131 |
2.45e-1 |
SMART |
|
CA
|
155 |
240 |
1.05e-18 |
SMART |
|
CA
|
264 |
345 |
6.52e-24 |
SMART |
|
CA
|
369 |
450 |
5.99e-23 |
SMART |
|
CA
|
474 |
560 |
6.99e-24 |
SMART |
|
CA
|
591 |
669 |
5.31e-15 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
932 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193869
|
| SMART Domains |
Protein: ENSMUSP00000141482
Gene: ENSMUSG00000103332
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
CA
|
45 |
131 |
1.64e-2 |
SMART |
|
CA
|
155 |
240 |
6.42e-23 |
SMART |
|
CA
|
264 |
345 |
1.76e-20 |
SMART |
|
CA
|
369 |
450 |
2.27e-23 |
SMART |
|
CA
|
474 |
560 |
1.5e-23 |
SMART |
|
CA
|
591 |
669 |
1.17e-16 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
912 |
931 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193984
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194190
|
| SMART Domains |
Protein: ENSMUSP00000142062
Gene: ENSMUSG00000103144
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
CA
|
31 |
131 |
3.16e-2 |
SMART |
|
CA
|
155 |
240 |
5.39e-16 |
SMART |
|
CA
|
264 |
345 |
6.72e-26 |
SMART |
|
CA
|
369 |
450 |
1.32e-24 |
SMART |
|
CA
|
474 |
560 |
4.17e-22 |
SMART |
|
CA
|
591 |
669 |
4.48e-13 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
912 |
931 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194418
|
| SMART Domains |
Protein: ENSMUSP00000142140
Gene: ENSMUSG00000103677
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
44 |
130 |
1.64e-2 |
SMART |
|
CA
|
154 |
239 |
3.93e-18 |
SMART |
|
CA
|
263 |
344 |
5.22e-23 |
SMART |
|
CA
|
368 |
449 |
5.02e-25 |
SMART |
|
CA
|
473 |
559 |
2.07e-26 |
SMART |
|
CA
|
590 |
668 |
6.84e-18 |
SMART |
|
transmembrane domain
|
690 |
712 |
N/A |
INTRINSIC |
|
low complexity region
|
911 |
930 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194544
|
| SMART Domains |
Protein: ENSMUSP00000141847
Gene: ENSMUSG00000102836
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:CA
|
18 |
66 |
5e-20 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195112
|
| SMART Domains |
Protein: ENSMUSP00000141449
Gene: ENSMUSG00000102748
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
24 |
130 |
8.18e-3 |
SMART |
|
CA
|
154 |
239 |
1.39e-18 |
SMART |
|
CA
|
263 |
344 |
7.91e-23 |
SMART |
|
CA
|
368 |
449 |
2.27e-23 |
SMART |
|
CA
|
473 |
559 |
1.24e-24 |
SMART |
|
CA
|
590 |
671 |
1.3e-9 |
SMART |
|
transmembrane domain
|
690 |
712 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
928 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195363
|
| SMART Domains |
Protein: ENSMUSP00000142227
Gene: ENSMUSG00000103585
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
25 |
N/A |
INTRINSIC |
|
CA
|
56 |
131 |
1.47e-2 |
SMART |
|
CA
|
155 |
240 |
1.23e-19 |
SMART |
|
CA
|
264 |
343 |
5.54e-27 |
SMART |
|
CA
|
367 |
448 |
5.09e-26 |
SMART |
|
CA
|
472 |
558 |
1.98e-23 |
SMART |
|
CA
|
589 |
670 |
1.3e-9 |
SMART |
|
transmembrane domain
|
689 |
711 |
N/A |
INTRINSIC |
|
low complexity region
|
893 |
912 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195823
|
| SMART Domains |
Protein: ENSMUSP00000141803
Gene: ENSMUSG00000103793
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
13 |
24 |
N/A |
INTRINSIC |
|
CA
|
45 |
131 |
2.41e-2 |
SMART |
|
CA
|
155 |
240 |
5.77e-16 |
SMART |
|
CA
|
264 |
345 |
1.1e-21 |
SMART |
|
CA
|
369 |
450 |
2.75e-22 |
SMART |
|
low complexity region
|
453 |
462 |
N/A |
INTRINSIC |
|
CA
|
474 |
560 |
9.22e-24 |
SMART |
|
CA
|
591 |
669 |
2.4e-13 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
932 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1204 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
96% (50/52) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 53 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc1 |
C |
G |
16: 14,263,283 (GRCm39) |
P748A |
probably damaging |
Het |
| Abcc12 |
A |
G |
8: 87,293,182 (GRCm39) |
V2A |
probably damaging |
Het |
| Anxa3 |
T |
C |
5: 96,978,263 (GRCm39) |
Y216H |
probably damaging |
Het |
| Arpc1a |
C |
A |
5: 145,041,668 (GRCm39) |
T317K |
probably benign |
Het |
| C330018D20Rik |
A |
G |
18: 57,095,483 (GRCm39) |
L34S |
probably damaging |
Het |
| C5ar1 |
A |
G |
7: 15,982,504 (GRCm39) |
F172S |
probably damaging |
Het |
| Ccl27a |
G |
A |
4: 41,774,166 (GRCm39) |
|
probably benign |
Het |
| Clip1 |
T |
C |
5: 123,752,342 (GRCm39) |
N480D |
|
Het |
| Cttnbp2nl |
A |
G |
3: 104,912,076 (GRCm39) |
S603P |
possibly damaging |
Het |
| Dmc1 |
A |
T |
15: 79,480,443 (GRCm39) |
|
probably null |
Het |
| Dnhd1 |
A |
G |
7: 105,323,475 (GRCm39) |
I626V |
probably benign |
Het |
| Dnm2 |
A |
G |
9: 21,416,930 (GRCm39) |
N821S |
probably benign |
Het |
| Dst |
T |
C |
1: 34,238,509 (GRCm39) |
L1723S |
probably benign |
Het |
| Ep300 |
T |
A |
15: 81,492,399 (GRCm39) |
M245K |
unknown |
Het |
| Fam227a |
T |
C |
15: 79,501,967 (GRCm39) |
T536A |
probably benign |
Het |
| Fbn2 |
G |
T |
18: 58,213,299 (GRCm39) |
R963S |
possibly damaging |
Het |
| Fbxo42 |
T |
G |
4: 140,927,673 (GRCm39) |
I651S |
possibly damaging |
Het |
| Ggnbp1 |
T |
A |
17: 27,237,105 (GRCm39) |
M1K |
probably null |
Het |
| Gm10800 |
AAAGAAAACTGAA |
ACAAGAAAACTGAA |
2: 98,497,378 (GRCm39) |
|
probably null |
Het |
| Grid2 |
T |
C |
6: 63,908,085 (GRCm39) |
F242L |
possibly damaging |
Het |
| Igf2r |
A |
G |
17: 12,917,160 (GRCm39) |
V1580A |
possibly damaging |
Het |
| Marchf4 |
A |
G |
1: 72,574,148 (GRCm39) |
V50A |
possibly damaging |
Het |
| Mettl15 |
T |
A |
2: 108,923,220 (GRCm39) |
R401* |
probably null |
Het |
| Mki67 |
A |
T |
7: 135,301,106 (GRCm39) |
H1309Q |
probably benign |
Het |
| Mtor |
T |
C |
4: 148,547,252 (GRCm39) |
Y412H |
probably damaging |
Het |
| Myef2 |
C |
T |
2: 124,965,396 (GRCm39) |
G15S |
probably benign |
Het |
| Napepld |
A |
T |
5: 21,880,846 (GRCm39) |
I183N |
probably damaging |
Het |
| Nbeal2 |
T |
C |
9: 110,454,886 (GRCm39) |
E2644G |
probably benign |
Het |
| Neb |
C |
T |
2: 52,186,438 (GRCm39) |
R878Q |
possibly damaging |
Het |
| Or52l1 |
A |
G |
7: 104,829,956 (GRCm39) |
V203A |
probably damaging |
Het |
| Otol1 |
A |
T |
3: 69,935,202 (GRCm39) |
H398L |
probably damaging |
Het |
| Pramel19 |
T |
G |
4: 101,798,497 (GRCm39) |
F156C |
probably benign |
Het |
| Rhbdl1 |
T |
C |
17: 26,055,991 (GRCm39) |
S4G |
possibly damaging |
Het |
| Ric1 |
A |
G |
19: 29,557,175 (GRCm39) |
E420G |
probably benign |
Het |
| Sap30l |
G |
A |
11: 57,698,887 (GRCm39) |
R120H |
probably damaging |
Het |
| Scn2a |
T |
C |
2: 65,546,247 (GRCm39) |
F937L |
probably damaging |
Het |
| Sdf2 |
G |
A |
11: 78,141,989 (GRCm39) |
G108D |
probably damaging |
Het |
| Skint5 |
T |
C |
4: 113,381,305 (GRCm39) |
S1263G |
unknown |
Het |
| Stab1 |
A |
G |
14: 30,867,194 (GRCm39) |
I1722T |
probably benign |
Het |
| Syn3 |
A |
G |
10: 85,893,428 (GRCm39) |
S472P |
unknown |
Het |
| Tcp11l2 |
T |
C |
10: 84,430,622 (GRCm39) |
F249S |
probably damaging |
Het |
| Thoc7 |
T |
A |
14: 13,961,819 (GRCm38) |
|
probably null |
Het |
| Tvp23a |
C |
A |
16: 10,246,602 (GRCm39) |
C61F |
probably damaging |
Het |
| Ubfd1 |
G |
A |
7: 121,666,606 (GRCm39) |
G34D |
probably benign |
Het |
| Vmn1r160 |
A |
T |
7: 22,570,967 (GRCm39) |
T107S |
probably damaging |
Het |
| Vmn2r108 |
T |
A |
17: 20,692,457 (GRCm39) |
K133I |
probably benign |
Het |
| Vmn2r15 |
A |
T |
5: 109,436,190 (GRCm39) |
|
probably null |
Het |
| Wdr25 |
G |
A |
12: 108,958,819 (GRCm39) |
G344S |
possibly damaging |
Het |
| Zfp354c |
C |
T |
11: 50,708,635 (GRCm39) |
|
probably null |
Het |
| Zfp560 |
G |
T |
9: 20,260,206 (GRCm39) |
Q219K |
probably benign |
Het |
| Zfp691 |
C |
T |
4: 119,028,181 (GRCm39) |
G17E |
probably damaging |
Het |
| Zfp930 |
T |
A |
8: 69,661,810 (GRCm39) |
M1K |
probably null |
Het |
| Zkscan14 |
A |
G |
5: 145,132,169 (GRCm39) |
F454S |
probably benign |
Het |
|
| Other mutations in Pcdhga9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
PIT4468001:Pcdhga9
|
UTSW |
18 |
37,872,527 (GRCm39) |
nonsense |
probably null |
|
|
R2870:Pcdhga9
|
UTSW |
18 |
37,870,524 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2870:Pcdhga9
|
UTSW |
18 |
37,870,524 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2871:Pcdhga9
|
UTSW |
18 |
37,870,524 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2871:Pcdhga9
|
UTSW |
18 |
37,870,524 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2872:Pcdhga9
|
UTSW |
18 |
37,870,524 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2872:Pcdhga9
|
UTSW |
18 |
37,870,524 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2873:Pcdhga9
|
UTSW |
18 |
37,870,524 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R3727:Pcdhga9
|
UTSW |
18 |
37,871,995 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3918:Pcdhga9
|
UTSW |
18 |
37,871,995 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3939:Pcdhga9
|
UTSW |
18 |
37,871,995 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3940:Pcdhga9
|
UTSW |
18 |
37,871,995 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3946:Pcdhga9
|
UTSW |
18 |
37,870,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4397:Pcdhga9
|
UTSW |
18 |
37,871,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4576:Pcdhga9
|
UTSW |
18 |
37,870,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4617:Pcdhga9
|
UTSW |
18 |
37,871,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4810:Pcdhga9
|
UTSW |
18 |
37,871,601 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4903:Pcdhga9
|
UTSW |
18 |
37,872,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4941:Pcdhga9
|
UTSW |
18 |
37,871,185 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5042:Pcdhga9
|
UTSW |
18 |
37,870,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5641:Pcdhga9
|
UTSW |
18 |
37,871,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5743:Pcdhga9
|
UTSW |
18 |
37,871,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6762:Pcdhga9
|
UTSW |
18 |
37,870,321 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7140:Pcdhga9
|
UTSW |
18 |
37,872,184 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7804:Pcdhga9
|
UTSW |
18 |
37,871,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8088:Pcdhga9
|
UTSW |
18 |
37,870,007 (GRCm39) |
intron |
probably benign |
|
|
R8506:Pcdhga9
|
UTSW |
18 |
37,871,737 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTCAGTTAGCGCCCATGAC -3'
(R):5'- GACAACCAAGCATTCTGTCCAG -3'
Sequencing Primer
(F):5'- GAGGAGAATGCTAAGGTTACTTACTC -3'
(R):5'- AAGCATTCTGTCCAGAGTCTTTG -3'
|
| Posted On |
2019-10-24 |
Incidental Mutation