Incidental Mutation 'R7707:Traf7'
| ID |
628392 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Traf7
|
| Ensembl Gene |
ENSMUSG00000052752 |
| Gene Name |
TNF receptor-associated factor 7 |
| Synonyms |
RFWD1 |
| MMRRC Submission |
067893-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.644)
|
| Stock # |
R7707 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
24727824-24746912 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to T
at 24729683 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000134759
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000024958]
[ENSMUST00000070777]
[ENSMUST00000088464]
[ENSMUST00000176086]
[ENSMUST00000176178]
[ENSMUST00000176237]
[ENSMUST00000176324]
[ENSMUST00000176353]
[ENSMUST00000176652]
[ENSMUST00000176668]
[ENSMUST00000177025]
[ENSMUST00000177154]
[ENSMUST00000177193]
[ENSMUST00000177401]
[ENSMUST00000177405]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000024958
|
| SMART Domains |
Protein: ENSMUSP00000024958
Gene: ENSMUSG00000033597
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
48 |
77 |
9.93e-5 |
SMART |
|
ANK
|
81 |
110 |
1.9e-1 |
SMART |
|
ANK
|
114 |
143 |
1.51e-4 |
SMART |
|
ANK
|
147 |
176 |
1.15e0 |
SMART |
|
ANK
|
188 |
217 |
2.6e-8 |
SMART |
|
ANK
|
220 |
249 |
3.31e-1 |
SMART |
|
SH3
|
284 |
346 |
3.62e-5 |
SMART |
|
Pfam:Caskin1-CID
|
373 |
421 |
3e-26 |
PFAM |
|
SAM
|
473 |
539 |
3.63e-15 |
SMART |
|
SAM
|
542 |
609 |
5.41e-14 |
SMART |
|
low complexity region
|
631 |
647 |
N/A |
INTRINSIC |
|
low complexity region
|
667 |
679 |
N/A |
INTRINSIC |
|
low complexity region
|
715 |
724 |
N/A |
INTRINSIC |
|
low complexity region
|
841 |
863 |
N/A |
INTRINSIC |
|
Pfam:Caskin-Pro-rich
|
878 |
966 |
3e-37 |
PFAM |
|
low complexity region
|
1163 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1190 |
1216 |
N/A |
INTRINSIC |
|
low complexity region
|
1222 |
1232 |
N/A |
INTRINSIC |
|
low complexity region
|
1269 |
1288 |
N/A |
INTRINSIC |
|
low complexity region
|
1294 |
1312 |
N/A |
INTRINSIC |
|
low complexity region
|
1315 |
1333 |
N/A |
INTRINSIC |
|
low complexity region
|
1344 |
1359 |
N/A |
INTRINSIC |
|
Pfam:Caskin-tail
|
1369 |
1431 |
7.2e-33 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000070777
|
| SMART Domains |
Protein: ENSMUSP00000069334
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
RING
|
92 |
125 |
4.73e-6 |
SMART |
|
coiled coil region
|
264 |
332 |
N/A |
INTRINSIC |
|
WD40
|
344 |
383 |
8.35e-11 |
SMART |
|
WD40
|
387 |
424 |
8.42e-7 |
SMART |
|
WD40
|
427 |
463 |
2.09e-2 |
SMART |
|
WD40
|
468 |
504 |
1.92e0 |
SMART |
|
WD40
|
507 |
544 |
5.15e-2 |
SMART |
|
WD40
|
547 |
588 |
1.78e-5 |
SMART |
|
WD40
|
591 |
628 |
1.63e-4 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000088464
|
| SMART Domains |
Protein: ENSMUSP00000085812
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
117 |
N/A |
INTRINSIC |
|
RING
|
130 |
163 |
4.73e-6 |
SMART |
|
Pfam:zf-TRAF
|
221 |
277 |
3.4e-8 |
PFAM |
|
coiled coil region
|
304 |
372 |
N/A |
INTRINSIC |
|
WD40
|
384 |
423 |
8.35e-11 |
SMART |
|
WD40
|
427 |
464 |
8.42e-7 |
SMART |
|
WD40
|
467 |
503 |
2.09e-2 |
SMART |
|
WD40
|
508 |
544 |
1.92e0 |
SMART |
|
WD40
|
547 |
584 |
5.15e-2 |
SMART |
|
WD40
|
587 |
628 |
1.78e-5 |
SMART |
|
WD40
|
631 |
668 |
1.63e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000175698
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176086
|
| SMART Domains |
Protein: ENSMUSP00000135845
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
103 |
132 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176178
|
| SMART Domains |
Protein: ENSMUSP00000134808
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176237
|
| SMART Domains |
Protein: ENSMUSP00000134946
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
RING
|
91 |
124 |
4.73e-6 |
SMART |
|
Pfam:zf-TRAF
|
182 |
238 |
8.4e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176324
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000176353
|
| SMART Domains |
Protein: ENSMUSP00000135267
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
RING
|
92 |
125 |
4.73e-6 |
SMART |
|
coiled coil region
|
264 |
332 |
N/A |
INTRINSIC |
|
WD40
|
344 |
383 |
8.35e-11 |
SMART |
|
WD40
|
387 |
424 |
8.42e-7 |
SMART |
|
WD40
|
427 |
463 |
2.09e-2 |
SMART |
|
WD40
|
468 |
504 |
1.92e0 |
SMART |
|
WD40
|
507 |
544 |
5.15e-2 |
SMART |
|
WD40
|
547 |
588 |
1.78e-5 |
SMART |
|
WD40
|
591 |
628 |
1.63e-4 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000176652
|
| SMART Domains |
Protein: ENSMUSP00000134759
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
117 |
N/A |
INTRINSIC |
|
RING
|
130 |
163 |
4.73e-6 |
SMART |
|
coiled coil region
|
304 |
372 |
N/A |
INTRINSIC |
|
WD40
|
384 |
423 |
8.35e-11 |
SMART |
|
WD40
|
427 |
464 |
8.42e-7 |
SMART |
|
WD40
|
467 |
503 |
2.09e-2 |
SMART |
|
WD40
|
508 |
544 |
1.92e0 |
SMART |
|
WD40
|
547 |
584 |
5.15e-2 |
SMART |
|
WD40
|
587 |
628 |
1.78e-5 |
SMART |
|
WD40
|
631 |
668 |
1.63e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176668
|
| SMART Domains |
Protein: ENSMUSP00000135586
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177025
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177154
|
| SMART Domains |
Protein: ENSMUSP00000135874
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
91 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
118 |
N/A |
INTRINSIC |
|
RING
|
131 |
164 |
4.73e-6 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177193
|
| SMART Domains |
Protein: ENSMUSP00000135288
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
117 |
N/A |
INTRINSIC |
|
RING
|
130 |
163 |
4.73e-6 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177401
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177405
|
| SMART Domains |
Protein: ENSMUSP00000135127
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177502
|
| SMART Domains |
Protein: ENSMUSP00000134970
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
11 |
N/A |
INTRINSIC |
|
RING
|
24 |
68 |
4.24e-2 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
99% (72/73) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.[supplied by OMIM, Apr 2004]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2900026A02Rik |
T |
A |
5: 113,285,852 (GRCm39) |
M1L |
probably benign |
Het |
| Ap1s3 |
T |
C |
1: 79,591,964 (GRCm39) |
K129E |
probably benign |
Het |
| Ap3b2 |
C |
T |
7: 81,126,530 (GRCm39) |
V357I |
possibly damaging |
Het |
| Aplp1 |
A |
T |
7: 30,142,523 (GRCm39) |
C140S |
probably damaging |
Het |
| Arhgef1 |
G |
A |
7: 24,616,306 (GRCm39) |
D317N |
probably damaging |
Het |
| Asb4 |
A |
G |
6: 5,430,968 (GRCm39) |
H401R |
probably benign |
Het |
| Bpi |
A |
T |
2: 158,103,093 (GRCm39) |
E79D |
probably benign |
Het |
| Cant1 |
C |
T |
11: 118,301,724 (GRCm39) |
V198M |
possibly damaging |
Het |
| Casp9 |
C |
T |
4: 141,532,778 (GRCm39) |
R225C |
probably benign |
Het |
| Ccdc88b |
C |
A |
19: 6,834,837 (GRCm39) |
R82L |
probably benign |
Het |
| Cfap251 |
A |
T |
5: 123,391,950 (GRCm39) |
E28V |
probably benign |
Het |
| Chrm4 |
A |
G |
2: 91,757,699 (GRCm39) |
T36A |
probably benign |
Het |
| Cntln |
A |
T |
4: 84,802,853 (GRCm39) |
D51V |
probably damaging |
Het |
| Commd8 |
A |
T |
5: 72,320,081 (GRCm39) |
F120Y |
probably damaging |
Het |
| Cpne6 |
A |
C |
14: 55,753,771 (GRCm39) |
T410P |
probably damaging |
Het |
| Ctnnb1 |
A |
T |
9: 120,781,931 (GRCm39) |
I315F |
possibly damaging |
Het |
| Dnah9 |
A |
G |
11: 66,009,784 (GRCm39) |
V701A |
probably damaging |
Het |
| Efcab9 |
A |
G |
11: 32,472,851 (GRCm39) |
Y199H |
possibly damaging |
Het |
| Endou |
T |
A |
15: 97,610,983 (GRCm39) |
|
probably null |
Het |
| Fhip1a |
A |
G |
3: 85,583,560 (GRCm39) |
V412A |
probably benign |
Het |
| Foxc2 |
C |
T |
8: 121,844,641 (GRCm39) |
P430S |
probably benign |
Het |
| Gas2l3 |
T |
A |
10: 89,250,220 (GRCm39) |
K299N |
probably damaging |
Het |
| Gm10375 |
G |
A |
14: 43,842,332 (GRCm39) |
Q133* |
probably null |
Het |
| Gorab |
T |
C |
1: 163,220,009 (GRCm39) |
D211G |
probably damaging |
Het |
| Grin3b |
T |
A |
10: 79,811,735 (GRCm39) |
S747T |
possibly damaging |
Het |
| Gucd1 |
C |
A |
10: 75,347,120 (GRCm39) |
|
probably benign |
Het |
| Gucy2d |
T |
C |
7: 98,100,876 (GRCm39) |
F400L |
possibly damaging |
Het |
| Hivep3 |
G |
A |
4: 119,591,156 (GRCm39) |
V55M |
|
Het |
| Igsf3 |
A |
G |
3: 101,367,238 (GRCm39) |
N1157S |
probably benign |
Het |
| Irak3 |
A |
T |
10: 119,982,489 (GRCm39) |
D324E |
probably damaging |
Het |
| Jup |
G |
T |
11: 100,273,878 (GRCm39) |
A221D |
possibly damaging |
Het |
| Kctd17 |
CAGCTGGAGGAGC |
CAGC |
15: 78,321,113 (GRCm39) |
|
probably benign |
Het |
| Lgr4 |
A |
G |
2: 109,827,936 (GRCm39) |
|
probably null |
Het |
| Lrrc34 |
T |
C |
3: 30,679,041 (GRCm39) |
D352G |
probably benign |
Het |
| Metrn |
C |
A |
17: 26,014,384 (GRCm39) |
A175S |
probably benign |
Het |
| Nr2c1 |
T |
A |
10: 94,024,027 (GRCm39) |
S411T |
probably benign |
Het |
| Or4c11 |
A |
G |
2: 88,695,153 (GRCm39) |
D68G |
possibly damaging |
Het |
| Or5h22 |
T |
A |
16: 58,894,634 (GRCm39) |
I270F |
possibly damaging |
Het |
| Orc3 |
T |
A |
4: 34,598,691 (GRCm39) |
K172* |
probably null |
Het |
| Oxnad1 |
A |
G |
14: 31,823,965 (GRCm39) |
|
probably null |
Het |
| Pcdh7 |
A |
G |
5: 57,877,672 (GRCm39) |
N409S |
probably damaging |
Het |
| Pcdha11 |
A |
T |
18: 37,144,845 (GRCm39) |
N312I |
probably benign |
Het |
| Pds5a |
G |
T |
5: 65,767,476 (GRCm39) |
P121Q |
unknown |
Het |
| Phc1 |
A |
G |
6: 122,300,739 (GRCm39) |
I380T |
unknown |
Het |
| Phldb3 |
C |
A |
7: 24,326,022 (GRCm39) |
H535N |
possibly damaging |
Het |
| Proser3 |
T |
C |
7: 30,239,216 (GRCm39) |
Q600R |
probably benign |
Het |
| Ptprz1 |
A |
G |
6: 23,002,295 (GRCm39) |
M1462V |
probably benign |
Het |
| Pyroxd2 |
T |
C |
19: 42,726,586 (GRCm39) |
T243A |
probably damaging |
Het |
| Ralgapa1 |
C |
A |
12: 55,824,077 (GRCm39) |
D268Y |
probably null |
Het |
| Rapgef5 |
A |
C |
12: 117,679,079 (GRCm39) |
Y419S |
probably damaging |
Het |
| Rbm24 |
C |
A |
13: 46,582,605 (GRCm39) |
Q175K |
possibly damaging |
Het |
| Robo4 |
A |
T |
9: 37,324,418 (GRCm39) |
D982V |
probably damaging |
Het |
| Sbf2 |
T |
C |
7: 109,929,920 (GRCm39) |
|
probably null |
Het |
| Serping1 |
A |
T |
2: 84,604,043 (GRCm39) |
|
probably null |
Het |
| Shank1 |
C |
T |
7: 43,993,725 (GRCm39) |
S798F |
unknown |
Het |
| Slc15a5 |
A |
T |
6: 138,056,745 (GRCm39) |
M57K |
probably damaging |
Het |
| Slc35g1 |
T |
A |
19: 38,391,571 (GRCm39) |
C284* |
probably null |
Het |
| Src |
G |
A |
2: 157,306,578 (GRCm39) |
D194N |
probably damaging |
Het |
| Srfbp1 |
A |
G |
18: 52,616,726 (GRCm39) |
T84A |
probably damaging |
Het |
| Sspo |
A |
T |
6: 48,438,461 (GRCm39) |
T1510S |
probably benign |
Het |
| Taar1 |
A |
T |
10: 23,797,135 (GRCm39) |
I278F |
possibly damaging |
Het |
| Taf1a |
T |
C |
1: 183,185,583 (GRCm39) |
Y281H |
possibly damaging |
Het |
| Thbs3 |
A |
T |
3: 89,132,207 (GRCm39) |
Y798F |
possibly damaging |
Het |
| Tnpo1 |
T |
C |
13: 99,027,295 (GRCm39) |
T7A |
probably benign |
Het |
| Trbv19 |
G |
A |
6: 41,155,547 (GRCm39) |
V9I |
possibly damaging |
Het |
| Trim17 |
C |
T |
11: 58,856,110 (GRCm39) |
Q56* |
probably null |
Het |
| Ttn |
G |
T |
2: 76,732,406 (GRCm39) |
A4643E |
unknown |
Het |
| Ugt2b36 |
A |
G |
5: 87,229,367 (GRCm39) |
|
probably null |
Het |
| Uso1 |
A |
G |
5: 92,349,795 (GRCm39) |
*960W |
probably null |
Het |
| Usp2 |
G |
T |
9: 43,984,757 (GRCm39) |
|
probably null |
Het |
| Wdr20rt |
A |
G |
12: 65,272,981 (GRCm39) |
D148G |
probably damaging |
Het |
| Wif1 |
T |
C |
10: 120,919,864 (GRCm39) |
F204L |
probably damaging |
Het |
| Wwp1 |
T |
C |
4: 19,627,645 (GRCm39) |
D750G |
probably benign |
Het |
| Zfp1006 |
A |
T |
8: 129,945,660 (GRCm39) |
C388* |
probably null |
Het |
| Zmynd12 |
A |
T |
4: 119,302,063 (GRCm39) |
D234V |
probably damaging |
Het |
|
| Other mutations in Traf7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01674:Traf7
|
APN |
17 |
24,729,349 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01821:Traf7
|
APN |
17 |
24,729,473 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02263:Traf7
|
APN |
17 |
24,732,020 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02307:Traf7
|
APN |
17 |
24,732,020 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02321:Traf7
|
APN |
17 |
24,732,020 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02323:Traf7
|
APN |
17 |
24,732,020 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02636:Traf7
|
APN |
17 |
24,731,964 (GRCm39) |
missense |
probably benign |
|
|
Antediluvian
|
UTSW |
17 |
24,729,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Caveman
|
UTSW |
17 |
24,728,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Oldhat
|
UTSW |
17 |
24,731,266 (GRCm39) |
missense |
probably benign |
0.28 |
|
R0109:Traf7
|
UTSW |
17 |
24,732,900 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0109:Traf7
|
UTSW |
17 |
24,732,900 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0193:Traf7
|
UTSW |
17 |
24,729,525 (GRCm39) |
missense |
probably benign |
0.22 |
|
R1426:Traf7
|
UTSW |
17 |
24,730,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1484:Traf7
|
UTSW |
17 |
24,730,785 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1574:Traf7
|
UTSW |
17 |
24,729,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1574:Traf7
|
UTSW |
17 |
24,729,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1728:Traf7
|
UTSW |
17 |
24,731,353 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1729:Traf7
|
UTSW |
17 |
24,731,353 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1784:Traf7
|
UTSW |
17 |
24,731,353 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1959:Traf7
|
UTSW |
17 |
24,732,255 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1994:Traf7
|
UTSW |
17 |
24,729,476 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2484:Traf7
|
UTSW |
17 |
24,730,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4682:Traf7
|
UTSW |
17 |
24,732,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4778:Traf7
|
UTSW |
17 |
24,729,412 (GRCm39) |
unclassified |
probably benign |
|
|
R4779:Traf7
|
UTSW |
17 |
24,729,412 (GRCm39) |
unclassified |
probably benign |
|
|
R4781:Traf7
|
UTSW |
17 |
24,729,412 (GRCm39) |
unclassified |
probably benign |
|
|
R5120:Traf7
|
UTSW |
17 |
24,737,718 (GRCm39) |
nonsense |
probably null |
|
|
R6594:Traf7
|
UTSW |
17 |
24,728,813 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6885:Traf7
|
UTSW |
17 |
24,731,266 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7396:Traf7
|
UTSW |
17 |
24,728,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7669:Traf7
|
UTSW |
17 |
24,732,282 (GRCm39) |
nonsense |
probably null |
|
|
R8087:Traf7
|
UTSW |
17 |
24,731,038 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R8557:Traf7
|
UTSW |
17 |
24,729,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8932:Traf7
|
UTSW |
17 |
24,731,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Traf7
|
UTSW |
17 |
24,746,737 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R9539:Traf7
|
UTSW |
17 |
24,729,333 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9679:Traf7
|
UTSW |
17 |
24,746,737 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R9680:Traf7
|
UTSW |
17 |
24,746,737 (GRCm39) |
critical splice donor site |
probably benign |
|
|
Z1177:Traf7
|
UTSW |
17 |
24,728,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCATGTTGTGGGAAGACACC -3'
(R):5'- CAGCTCAGCCGTCAAATGATTC -3'
Sequencing Primer
(F):5'- CACCAGTGTGCATACAGGGTTG -3'
(R):5'- GCCGTCAAATGATTCCCAGTCTAG -3'
|
| Posted On |
2020-03-19 |
Incidental Mutation